Production of DNA strand breaks by N-nitrosodimethylamine and 2-amino- 3-methylimidazo[4,5-f]quinoline in THLE cells expressing human CYP isoenzymes and inhibition by sulforaphane

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 402, Issue 1-2, 1998, Pages 111-120

  Barcelo S ^a,b   Mace K ^c   Pfeifer, A M A ^c   Chipman, J K ^b  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Chemoprevention; Comet assay; CYP1A2; CYP2E1; Sulforaphane

Indexed keywords

2 AMINO 3 METHYLIMIDAZO[4,5 F]QUINOLINE; DIMETHYLNITROSAMINE;

ANTINEOPLASTIC ACTIVITY; CANCER PREVENTION; CHEMICAL CARCINOGENESIS; CONFERENCE PAPER; CYTOTOXICITY; DNA STRAND BREAKAGE; GENOTOXICITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANTIMUTAGENIC AGENTS; CELL LINE; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP2E1; DIMETHYLNITROSAMINE; DNA DAMAGE; ENZYME INHIBITORS; HUMANS; MUTAGENS; QUINOLINES; THIOCYANATES;

EID: 0032543382     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00288-1     Document Type: Conference Paper

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