-
1
-
-
9044254525
-
P450 superfamily: Update on new sequences, gene mapping, accession numbers and nomenclature
-
Nelson, D.R. et al. (1996) P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature. Pharmacogenetics, 12, 1-51.
-
(1996)
Pharmacogenetics
, vol.12
, pp. 1-51
-
-
Nelson, D.R.1
-
2
-
-
0027178457
-
Hydroxylation and dealkylation of methyl-n-butylnitrosamine and role of certain cytochrome P-450 isozymes in these reactions
-
Huang, Q., Wang, S., Chen, S.C., Babcook, D.M., Park, S.S., Gelboin, H.V. and Mirvish, S.S. (1993) Hydroxylation and dealkylation of methyl-n-butylnitrosamine and role of certain cytochrome P-450 isozymes in these reactions. Cancer Lett., 69, 107-116.
-
(1993)
Cancer Lett.
, vol.69
, pp. 107-116
-
-
Huang, Q.1
Wang, S.2
Chen, S.C.3
Babcook, D.M.4
Park, S.S.5
Gelboin, H.V.6
Mirvish, S.S.7
-
3
-
-
0024514295
-
Substrate specificity and alkyl group selectivity in the metabolism of N-nitrosodialkylamines
-
Lee, M., Ishizaki, H., Brady, J.F. and Yang, C.S. (1989) Substrate specificity and alkyl group selectivity in the metabolism of N-nitrosodialkylamines. Cancer Res., 49, 1470-1474.
-
(1989)
Cancer Res.
, vol.49
, pp. 1470-1474
-
-
Lee, M.1
Ishizaki, H.2
Brady, J.F.3
Yang, C.S.4
-
4
-
-
0026593478
-
N-Nitrosodialkylamine dealkylation in reconstituted systems containing cytochrome P-450 purified from phenobarbital and β-naphthoflavone treated rats
-
Kawanishi, T., Ohno, Y., Takanaka, A., Kawano, S., Yamazoe, Y., Kato, R. and Omori, Y. (1992) N-Nitrosodialkylamine dealkylation in reconstituted systems containing cytochrome P-450 purified from phenobarbital and β-naphthoflavone treated rats. Arch. Toxicol., 66, 137-142.
-
(1992)
Arch. Toxicol.
, vol.66
, pp. 137-142
-
-
Kawanishi, T.1
Ohno, Y.2
Takanaka, A.3
Kawano, S.4
Yamazoe, Y.5
Kato, R.6
Omori, Y.7
-
5
-
-
0023877321
-
Metabolism of N-nitrosodialkylamines by human liver microsomes
-
Yoo, J.S.H., Guengerich, F.P. and Yang, C.S. (1988) Metabolism of N-nitrosodialkylamines by human liver microsomes. Cancer Res., 88, 1499-1504.
-
(1988)
Cancer Res.
, vol.88
, pp. 1499-1504
-
-
Yoo, J.S.H.1
Guengerich, F.P.2
Yang, C.S.3
-
6
-
-
0027270458
-
High variability of metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans
-
Camus, A.M., Geneste, O., Honkakoski, P., Béréziat, J.C., Henderson, C.J., Wolf, C.R., Bartsch, H. and Lang, M.A. (1993) High variability of metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans. Mol. Carcinogen., 7, 268-275.
-
(1993)
Mol. Carcinogen.
, vol.7
, pp. 268-275
-
-
Camus, A.M.1
Geneste, O.2
Honkakoski, P.3
Béréziat, J.C.4
Henderson, C.J.5
Wolf, C.R.6
Bartsch, H.7
Lang, M.A.8
-
7
-
-
0026744568
-
Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes
-
Yamazaki, H., Inui, Y., Yun, C.H., Guengerich, F.P. and Shimada, T. (1992) Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes. Carcinogenesis, 13, 1789-1794.
-
(1992)
Carcinogenesis
, vol.13
, pp. 1789-1794
-
-
Yamazaki, H.1
Inui, Y.2
Yun, C.H.3
Guengerich, F.P.4
Shimada, T.5
-
8
-
-
0025992864
-
Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes
-
Guengerich, F.P. and Shimada, T. (1991) Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes. Chem. Res. Toxicol., 4, 391-407.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 391-407
-
-
Guengerich, F.P.1
Shimada, T.2
-
9
-
-
0026035519
-
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects
-
Guengerich, F.P., Kim, D.H. and Iwasaki, M. (1991) Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. Chem. Res. Toxicol., 4, 168-179.
-
(1991)
Chem. Res. Toxicol.
, vol.4
, pp. 168-179
-
-
Guengerich, F.P.1
Kim, D.H.2
Iwasaki, M.3
-
10
-
-
0022827585
-
Ethanol oxidation and toxicity: Role of alcohol P-450 oxygenase
-
Koop, D.R. and Coon, M.J. (1986) Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase. Alcohol Clin. Exp. Res., 10, 445-495.
-
(1986)
Alcohol Clin. Exp. Res.
, vol.10
, pp. 445-495
-
-
Koop, D.R.1
Coon, M.J.2
-
11
-
-
0026082836
-
cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment
-
Gonzalez, F.J., Crespi, C.L. and Gelboin, H.V. (1991) cDNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment. Mutat. Res., 247, 113-127.
-
(1991)
Mutat. Res.
, vol.247
, pp. 113-127
-
-
Gonzalez, F.J.1
Crespi, C.L.2
Gelboin, H.V.3
-
12
-
-
0021806780
-
Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P450 of rabbit liver microsomes by diverse agents: Ethanol, imidazole, trichlorethylene, acetone, pyrazole and isoniazid
-
Koop, D., Crump, B.L., Nordblom, G.D. and Coon, M.J. (1985) Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichlorethylene, acetone, pyrazole and isoniazid. Proc. Natl Acad. Sci. USA, 82, 4065-4069.
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, pp. 4065-4069
-
-
Koop, D.1
Crump, B.L.2
Nordblom, G.D.3
Coon, M.J.4
-
13
-
-
0024506260
-
Comparison of caffeine metabolism by slices, microsomes and hepatocyte cultures from adult human liver
-
Berthou, F., Ratanasavanh, D., Riché, C., Picart, D., Voirin, T. and Guillouzo, A. (1989) Comparison of caffeine metabolism by slices, microsomes and hepatocyte cultures from adult human liver. Xenobiotica, 19, 401-417.
-
(1989)
Xenobiotica
, vol.19
, pp. 401-417
-
-
Berthou, F.1
Ratanasavanh, D.2
Riché, C.3
Picart, D.4
Voirin, T.5
Guillouzo, A.6
-
14
-
-
0028232498
-
Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes
-
Berthou, F., Dréano, Y., Belloc, C., Kangas, L., Gautier, J.C. and Beaune, P. (1994) Involvement of cytochrome P450 3A enzyme family in the major metabolic pathways of toremifene in human liver microsomes. Biochem. Pharmacol., 47, 1883-1895.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 1883-1895
-
-
Berthou, F.1
Dréano, Y.2
Belloc, C.3
Kangas, L.4
Gautier, J.C.5
Beaune, P.6
-
15
-
-
0023060630
-
Determination of free acetaldehyde in blood as the dinitrophenylhydrazone derivative by high-performance liquid chromatography
-
Lucas, D., Ménez, J.F., Berthou, F., Pennec, Y. and Floch, H.H. (1986) Determination of free acetaldehyde in blood as the dinitrophenylhydrazone derivative by high-performance liquid chromatography. J. Chromatogr., 382, 57-66.
-
(1986)
J. Chromatogr.
, vol.382
, pp. 57-66
-
-
Lucas, D.1
Ménez, J.F.2
Berthou, F.3
Pennec, Y.4
Floch, H.H.5
-
16
-
-
0028106482
-
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat
-
Burke, M.D., Thompson, S., Weaver, R.J., Wolf, C.R. and Mayer, R.T. (1994) Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat. Biochem. Pharmacol., 48, 923-936.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 923-936
-
-
Burke, M.D.1
Thompson, S.2
Weaver, R.J.3
Wolf, C.R.4
Mayer, R.T.5
-
17
-
-
0025014594
-
Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP 2C subfamily
-
Relling, M.V., Aoyama, T., Gonzalez, F.J. and Meyer, U.A. (1990) Tolbutamide and mephenytoin hydroxylation by human cytochrome P450s in the CYP 2C subfamily. J. Pharmacol. Exp. Ther., 252, 442-447.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 442-447
-
-
Relling, M.V.1
Aoyama, T.2
Gonzalez, F.J.3
Meyer, U.A.4
-
18
-
-
0027265750
-
P450 2D6 and P450 3A-dependent metabolism of dextromethorphan in humans
-
Jacqz-Aigrin, C., Funck-Brentano, C. and Cresteil, T. (1993) P450 2D6 and P450 3A-dependent metabolism of dextromethorphan in humans. Pharmacogenetics, 3, 197-204.
-
(1993)
Pharmacogenetics
, vol.3
, pp. 197-204
-
-
Jacqz-Aigrin, C.1
Funck-Brentano, C.2
Cresteil, T.3
-
19
-
-
0027438967
-
Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone
-
Carrière, V., Goasduff, T., Ratanasavanh, D., Morel, F., Gautier, J.C., Guillouzo, A., Beaune, P. and Berthou, F. (1993) Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone. Chem. Res. Toxicol., 6, 852-857.
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 852-857
-
-
Carrière, V.1
Goasduff, T.2
Ratanasavanh, D.3
Morel, F.4
Gautier, J.C.5
Guillouzo, A.6
Beaune, P.7
Berthou, F.8
-
20
-
-
0027253618
-
HPLC assay for 4-nitrophenol hydroxylation, a putative cytochrome P-450 2E1 activity, in human liver microsomes
-
Tassaneeyakul, W., Veronese, M.E., Birkett, D.J. and Miners, J.O. (1993) HPLC assay for 4-nitrophenol hydroxylation, a putative cytochrome P-450 2E1 activity, in human liver microsomes. J. Chromatogr., 616, 73-78.
-
(1993)
J. Chromatogr.
, vol.616
, pp. 73-78
-
-
Tassaneeyakul, W.1
Veronese, M.E.2
Birkett, D.J.3
Miners, J.O.4
-
21
-
-
0022998708
-
Characterization of rat and human liver microsomal cytochrome P450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism
-
Guengerich, F.P., Martin, M.V., Beaune, P.H., Kremers, F., Wolff, T. and Waxman, D.J. (1986) Characterization of rat and human liver microsomal cytochrome P450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. J. Biol. Chem., 261, 5051-5060.
-
(1986)
J. Biol. Chem.
, vol.261
, pp. 5051-5060
-
-
Guengerich, F.P.1
Martin, M.V.2
Beaune, P.H.3
Kremers, F.4
Wolff, T.5
Waxman, D.J.6
-
22
-
-
0013794926
-
A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes
-
Creaven, P.J., Parke, D.V. and Williams, R.T. (1965) A spectrofluorimetric study of the 7-hydroxylation of coumarin by liver microsomes. Biochem. J., 96, 390-398.
-
(1965)
Biochem. J.
, vol.96
, pp. 390-398
-
-
Creaven, P.J.1
Parke, D.V.2
Williams, R.T.3
-
23
-
-
0029071838
-
Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC
-
Mirvish, S.S. (1995) Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC. Cancer Lett., 93, 17-48
-
(1995)
Cancer Lett.
, vol.93
, pp. 17-48
-
-
Mirvish, S.S.1
-
24
-
-
0021680014
-
Relevance of nitrosamines to human cancer
-
Bartsh, H. and Montesano, R. (1984) Relevance of nitrosamines to human cancer. Carcinogenesis, 5, 1381-1393.
-
(1984)
Carcinogenesis
, vol.5
, pp. 1381-1393
-
-
Bartsh, H.1
Montesano, R.2
-
25
-
-
0025635625
-
Roles of cytochrome P450 IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes
-
Yoo, J.S.H., Ishizaki, H. and Yang, C.S. (1990) Roles of cytochrome P450 IIE1 in the dealkylation and denitrosation of N-nitrosodimethylamine and N-nitrosodiethylamine in rat liver microsomes. Carcinogenesis, 11, 2239-2243.
-
(1990)
Carcinogenesis
, vol.11
, pp. 2239-2243
-
-
Yoo, J.S.H.1
Ishizaki, H.2
Yang, C.S.3
-
26
-
-
0025757011
-
Comparison of levels of several human microsomal cytochrome P450 enzyme and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples
-
Guengerich, F.P. and Turvy, C.G. (1991) Comparison of levels of several human microsomal cytochrome P450 enzyme and epoxide hydrolase in normal and disease states using immunochemical analysis of surgical liver samples. J. Pharmacol. Exp. Ther., 256, 1189-1194.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.256
, pp. 1189-1194
-
-
Guengerich, F.P.1
Turvy, C.G.2
-
27
-
-
0028237729
-
Interindividual variation in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 Japanese and 30 Caucasians
-
Shimada, T., Minara, M., Inui, Y. and Guengerich, F.P. (1994) Interindividual variation in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. J. Pharmacol. Exp. Ther., 270, 414-423.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 414-423
-
-
Shimada, T.1
Minara, M.2
Inui, Y.3
Guengerich, F.P.4
-
28
-
-
0025022689
-
The CYP2A3 gene product catalyses coumarin 7-hydroxylation in human liver microsomes
-
Yamano, S., Tatsuno, J. and Gonzalez, F.J. (1990) The CYP2A3 gene product catalyses coumarin 7-hydroxylation in human liver microsomes. Biochemisty, 29, 1322-1329.
-
(1990)
Biochemisty
, vol.29
, pp. 1322-1329
-
-
Yamano, S.1
Tatsuno, J.2
Gonzalez, F.J.3
-
29
-
-
0030024786
-
Effect of the length of alkyl chain on the cytochrome P450 dependent metabolism of N-dialkylnitrosamines
-
Bellec, G., Goasduff, T., Dréano, Y., Ménez, J.F. and Berthou, F. (1996) Effect of the length of alkyl chain on the cytochrome P450 dependent metabolism of N-dialkylnitrosamines. Cancer Lett., 100, 115-123.
-
(1996)
Cancer Lett.
, vol.100
, pp. 115-123
-
-
Bellec, G.1
Goasduff, T.2
Dréano, Y.3
Ménez, J.F.4
Berthou, F.5
-
30
-
-
0028954947
-
Probing the active sites of rat and human cytochrome P450 2E1 with alcohols and carboxylic acids
-
Wang, M.H., Wade, D., Chen, L., White, S. and Yang, C.S. (1995) Probing the active sites of rat and human cytochrome P450 2E1 with alcohols and carboxylic acids. Arch. Biochem. Biophys., 317, 299-304.
-
(1995)
Arch. Biochem. Biophys.
, vol.317
, pp. 299-304
-
-
Wang, M.H.1
Wade, D.2
Chen, L.3
White, S.4
Yang, C.S.5
-
31
-
-
0030034986
-
Active site topology of human cytochrome P450 2E1
-
Ortiz de Montanello, P. (1996) Active site topology of human cytochrome P450 2E1. Chem. Res. Toxicol., 9, 223-226.
-
(1996)
Chem. Res. Toxicol.
, vol.9
, pp. 223-226
-
-
Ortiz De Montanello, P.1
|