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Volumn 10, Issue 1, 1997, Pages 85-92

Development of CYP450-expressing human bronchial epithelial cell lines for in vitro pharmacotoxicologic applications

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN B1; COMPLEMENTARY DNA; COUMARIN DERIVATIVE; CYTOCHROME P450; DIMETHYLNITROSAMINE; RESORUFIN DERIVATIVE;

EID: 0031007641     PISSN: 10979336     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 0024412071 scopus 로고
    • Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver: CDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine
    • AOYAMA, T., YAMANO, S., WAXMAN, D.J., LAPENSON, D.P., MEYER, U.A., FISHER, V., TYNDALE, R., INABA, T., WERNER, K., GELBOIN, H.V., and GONZALEZ, F.J. (1989). Cytochrome P-450 hPCN3, a novel cytochrome P-450 IIIA gene product that is differentially expressed in adult human liver: cDNA and deduced amino acid sequence and distinct specificities of cDNA-expressed hPCN1 and hPCN3 for the metabolism of steroid hormones and cyclosporine. J. Biol. Chem. 264, 10388-10395.
    • (1989) J. Biol. Chem. , vol.264 , pp. 10388-10395
    • Aoyama, T.1    Yamano, S.2    Waxman, D.J.3    Lapenson, D.P.4    Meyer, U.A.5    Fisher, V.6    Tyndale, R.7    Inaba, T.8    Werner, K.9    Gelboin, H.V.10    Gonzalez, F.J.11
  • 2
    • 0029036087 scopus 로고
    • Interaction between two probes used for phenotyping cytochrome P450 1A2 (caffeine) and P450 2E1 (chlorzoxazone) in humans
    • BERTHOU, F., GOASDUFF, T., LUCAS, D., DREANO, Y., LE BOT, M.H., and MÉNEZ, J.F. (1995). Interaction between two probes used for phenotyping cytochrome P450 1A2 (caffeine) and P450 2E1 (chlorzoxazone) in humans. Pharmacogenetics 5, 72-79.
    • (1995) Pharmacogenetics , vol.5 , pp. 72-79
    • Berthou, F.1    Goasduff, T.2    Lucas, D.3    Dreano, Y.4    Le Bot, M.H.5    Ménez, J.F.6
  • 3
    • 0025848338 scopus 로고
    • A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6
    • CRESPI, C.L., PENMAN, B.W., GELBOIN, H.V., and GONZALEZ, F.J. (1991). A tobacco smoke-derived nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P4502D6. Carcinogenesis 12, 1197-1201.
    • (1991) Carcinogenesis , vol.12 , pp. 1197-1201
    • Crespi, C.L.1    Penman, B.W.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 4
    • 0025179176 scopus 로고
    • Human cytochrome P450IIA3: CDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1
    • CRESPI, C.L., PENMAN, B.W., LEAKEY, J.A.E., ARLOTTO, M.P., STARK, A., PARKINSON, A., TURNER, T., STEIMEL, D.T., RUDO, K., DAVIES, R.L., and LANGENBACH, R. (1990). Human cytochrome P450IIA3: cDNA sequence, role of the enzyme in the metabolic activation of promutagens, comparison to nitrosamine activation by human cytochrome P450IIE1. Carcinogenesis 11, 1293-1300.
    • (1990) Carcinogenesis , vol.11 , pp. 1293-1300
    • Crespi, C.L.1    Penman, B.W.2    Leakey, J.A.E.3    Arlotto, M.P.4    Stark, A.5    Parkinson, A.6    Turner, T.7    Steimel, D.T.8    Rudo, K.9    Davies, R.L.10    Langenbach, R.11
  • 5
    • 0029033092 scopus 로고
    • Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture
    • DONATO, M.T., CASTELL, J.V., and GOMEZ-LECHON, M.J. (1995). Effect of model inducers on cytochrome P450 activities of human hepatocytes in primary culture. Drug Metab. Dispos. 23, 553-558.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 553-558
    • Donato, M.T.1    Castell, J.V.2    Gomez-Lechon, M.J.3
  • 6
    • 0029163541 scopus 로고
    • Nitric oxide and ethylnitrosurea: Relative mutagenicity in the p53 tumor suppressor and hypoxanthine-phosphoribosyltransferase genes
    • FELLEY-BOSCO, E., MIRKOVITCH, J., AMBS, S., MACÉ, K., PFEIFER, A., KEEPER, L.K., and HARRIS, C.C. (1995). Nitric oxide and ethylnitrosurea: Relative mutagenicity in the p53 tumor suppressor and hypoxanthine-phosphoribosyltransferase genes. Carcinogenesis 16, 2069-2074.
    • (1995) Carcinogenesis , vol.16 , pp. 2069-2074
    • Felley-Bosco, E.1    Mirkovitch, J.2    Ambs, S.3    MacÉ, K.4    Pfeifer, A.5    Keeper, L.K.6    Harris, C.C.7
  • 7
    • 0026082836 scopus 로고
    • cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment
    • GONZALEZ, F.J., CRESPI, C.L., and GELBOIN, H.V. (1991). cDNA-expressed human cytochrome P450s: A new age of molecular toxicology and human risk assessment. Mutat. Res. 247, 113-127.
    • (1991) Mutat. Res. , vol.247 , pp. 113-127
    • Gonzalez, F.J.1    Crespi, C.L.2    Gelboin, H.V.3
  • 9
    • 0023858226 scopus 로고
    • Human P450PCN1: Sequence, chromosome, localization and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase
    • GONZALEZ, F.J., B.J. UMENO, M., MCBRIDE, O.W., HARDWICK, J.P., MEYER, U.A., GELBOIN, H.V., and IDLE, J.R. (1988b). Human P450PCN1: Sequence, chromosome, localization and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase. DNA 7, 76-86.
    • (1988) DNA , vol.7 , pp. 76-86
    • Gonzalez, F.J.1    J., B.2    Umeno, M.3    Mcbride, O.W.4    Hardwick, J.P.5    Meyer, U.A.6    Gelboin, H.V.7    Idle, J.R.8
  • 10
    • 0020466499 scopus 로고
    • Clonal growth of normal adult human bronchial epithelial cells in a serum-free medium
    • LECHNER, J.F., HAUGEN, A., MCCLENDON, I.A., and PETTIS, E.W. (1982). Clonal growth of normal adult human bronchial epithelial cells in a serum-free medium. In Vitro 18, 633-642.
    • (1982) In Vitro , vol.18 , pp. 633-642
    • Lechner, J.F.1    Haugen, A.2    Mcclendon, I.A.3    Pettis, E.W.4
  • 11
    • 0022357460 scopus 로고
    • A serum-free method for culturing normal human bronchial epithelial cells at clonal density
    • LECHNER, J.F., and LA VECK, M.A. (1985). A serum-free method for culturing normal human bronchial epithelial cells at clonal density. J. Tissue Culture Methods 9, 43-48.
    • (1985) J. Tissue Culture Methods , vol.9 , pp. 43-48
    • Lechner, J.F.1    La Veck, M.A.2
  • 12
  • 13
    • 0001285525 scopus 로고    scopus 로고
    • Drug metabolism and carcinogen activation studies with human genetically engineered cells
    • J.V. Castell and M.J. Gomez-Lechon (eds.) Academic Press: London
    • MACÉ, K., OFFORD, E.A., and PFEIFER, A.M.A. (1996). Drug metabolism and carcinogen activation studies with human genetically engineered cells, in: In Vitro Methods in Pharmceutical Research. J.V. Castell and M.J. Gomez-Lechon (eds.) Academic Press: London, pp. 433-456.
    • (1996) In Vitro Methods in Pharmceutical Research , pp. 433-456
    • MacÉ, K.1    Offord, E.A.2    Pfeifer, A.M.A.3
  • 14
    • 29344433717 scopus 로고    scopus 로고
    • Mechanisms involved in the chemoprotective effects of rosemary extract studied in human liver and bronchial cells
    • In Press
    • OFFORD, E.A., MACÉ, K., AVANTI, O., and PFEIFER, A.M.A. (1996). Mechanisms involved in the chemoprotective effects of rosemary extract studied in human liver and bronchial cells. Cancer Lett. In Press.
    • (1996) Cancer Lett.
    • Offord, E.A.1    MacÉ, K.2    Avanti, O.3    Pfeifer, A.M.A.4
  • 15
    • 0029101484 scopus 로고
    • Rosemary components inhibit benzo(a)pyrene-induced genotoxicity in human bronchial cells
    • OFFORD, E.A., MACÉ, K., RUFFIEUX, C., MALNOË, A., and PFEIFER, A.M.A. (1995). Rosemary components inhibit benzo(a)pyrene-induced genotoxicity in human bronchial cells. Carcinogenesis 16, 2057-2062.
    • (1995) Carcinogenesis , vol.16 , pp. 2057-2062
    • Offord, E.A.1    MacÉ, K.2    Ruffieux, C.3    Malnoë, A.4    Pfeifer, A.M.A.5
  • 17
    • 0024805129 scopus 로고
    • Cooperation of c-ras-1 and c-myc protooncogenes in the neoplastic transformation of SV40 T-antigen immortalized human bronchial epithelial cells
    • PFEIFER, A., MARK, G.E., MALAN-SHIBLEY, L., GRAZIANO, S.L., AMSTAD, P., and HARRIS, C.C. (1989). Cooperation of c-ras-1 and c-myc protooncogenes in the neoplastic transformation of SV40 T-antigen immortalized human bronchial epithelial cells. Proc. Natl. Acad. Sci. USA 86, 10075-10079.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 10075-10079
    • Pfeifer, A.1    Mark, G.E.2    Malan-Shibley, L.3    Graziano, S.L.4    Amstad, P.5    Harris, C.C.6
  • 18
    • 0023944920 scopus 로고
    • Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate co-precipitation with a plasmid containing SV40 early region genes
    • REDDEL, R.R., KE, Y., GERWIN, B.I., MCMENAMIN, M.G., LECHNER, J.F., SU, R.T., BRASH, D.E., PARK, J.B., RHIM, J.S., and HARRIS, C.C. (1988). Transformation of human bronchial epithelial cells by infection with SV40 or adenovirus-12 SV40 hybrid virus, or transfection via strontium phosphate co-precipitation with a plasmid containing SV40 early region genes. Cancer Res. 48, 1904-1909.
    • (1988) Cancer Res. , vol.48 , pp. 1904-1909
    • Reddel, R.R.1    Ke, Y.2    Gerwin, B.I.3    Mcmenamin, M.G.4    Lechner, J.F.5    Su, R.T.6    Brash, D.E.7    Park, J.B.8    Rhim, J.S.9    Harris, C.C.10
  • 19
    • 0022869269 scopus 로고
    • Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P450s
    • SONG, B.-J., GELBOIN, H.V., PARK, S.-S., YANG, C.S., and GONZALEZ, F.J. (1986). Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P450s. J. Biol. Chem. 261, 16689-16697.
    • (1986) J. Biol. Chem. , vol.261 , pp. 16689-16697
    • Song, B.-J.1    Gelboin, H.V.2    Park, S.-S.3    Yang, C.S.4    Gonzalez, F.J.5
  • 20
    • 0018380453 scopus 로고
    • Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo
    • STRAUSS, G.H., and ALBERTINI, R.J. (1979). Enumeration of 6-thioguanine-resistant peripheral blood lymphocytes in man as a potential test for somatic cell mutations arising in vivo. Mutat. Res. 61, 353-379.
    • (1979) Mutat. Res. , vol.61 , pp. 353-379
    • Strauss, G.H.1    Albertini, R.J.2
  • 23
    • 0024400702 scopus 로고
    • Identification of a polymorphically expressed member of the human cytochrome P-450III family
    • WRIGHTON, S.A., RING, B.J., WATKINS, P.B., and VANDENBRANDEN, M. (1989). Identification of a polymorphically expressed member of the human cytochrome P-450III family. J. Biol. Chem. 36, 97-105.
    • (1989) J. Biol. Chem. , vol.36 , pp. 97-105
    • Wrighton, S.A.1    Ring, B.J.2    Watkins, P.B.3    Vandenbranden, M.4
  • 24
    • 0024464027 scopus 로고
    • cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: Identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver
    • YAMANO, S., NHAMBURO, P.T., AOYAMA, T., MEYER, U.A., INABA, T., KALOW, W., GELBOIN, H.V., MCBRIDE, O.W., and GONZALEZ, F.J. (1989). cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: Identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver. Biochemisty 28, 7340-7348.
    • (1989) Biochemisty , vol.28 , pp. 7340-7348
    • Yamano, S.1    Nhamburo, P.T.2    Aoyama, T.3    Meyer, U.A.4    Inaba, T.5    Kalow, W.6    Gelboin, H.V.7    Mcbride, O.W.8    Gonzalez, F.J.9
  • 25
    • 0025022689 scopus 로고
    • The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes
    • YAMANO, S., TATSUNO, J., and GONZALEZ, F.J. (1990). The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes. Biochemistry 29, 1322-1329.
    • (1990) Biochemistry , vol.29 , pp. 1322-1329
    • Yamano, S.1    Tatsuno, J.2    Gonzalez, F.J.3
  • 26
    • 0023877321 scopus 로고
    • Metabolism of N-Nitrosodialkylamines by human liver microsomes
    • YOO, J.-S.H., GUENGERICH, F.P., and YANG, C.S. (1988). Metabolism of N-Nitrosodialkylamines by human liver microsomes. Cancer Res. 88, 1499-1504.
    • (1988) Cancer Res. , vol.88 , pp. 1499-1504
    • Yoo, J.-S.H.1    Guengerich, F.P.2    Yang, C.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.