Inhibition of N-nitrosodimethylamine demethylase in rat and human liver microsomes by isothiocyanates and their glutathione, L-cysteine, and N- acetyl-L-cysteine conjugates

Chemical Research in Toxicology

Volumn 9, Issue 6, 1996, Pages 932-938

  Jiao, Ding ^a   Clifford Conaway, C ^a   Wang, Mong Heng ^b   Yang, Chung S ^b   Koehl, Werner ^a,c   Chung, Fung Lung ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c University of Kaiserslautern ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; DIMETHYLNITROSAMINE DEMETHYLASE; GLUTATHIONE; ISOCYANIC ACID DERIVATIVE; NITROSAMINE;

ANIMAL TISSUE; ARTICLE; CHEMICAL CARCINOGENESIS; ENZYME INHIBITION; LIVER MICROSOME; LUNG CANCER; NONHUMAN; RAT;

ACETYLCYSTEINE; ANIMALS; CYSTEINE; CYTOCHROME P-450 CYP2E1; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUTATHIONE; HUMANS; ISOTHIOCYANATES; KINETICS; MALE; MICROSOMES, LIVER; RATS; RATS, INBRED F344;

EID: 9544258372     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx9502094     Document Type: Article

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