-
1
-
-
0025246367
-
The T lymphocyte in experimental allergic encephalomyelitis
-
Zamvil, S. S., and L. Steinman. 1990. The T lymphocyte in experimental allergic encephalomyelitis. Annu. Rev. Immunol. 8:579.
-
(1990)
Annu. Rev. Immunol.
, vol.8
, pp. 579
-
-
Zamvil, S.S.1
Steinman, L.2
-
2
-
-
0027368141
-
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
-
Kaufman, D. L., M. Clare-Salzler, J. Tian, T. Forsthuber, G. S. Ting, P. Robinson, M. A. Atkinson, E. E. Sercarz, A. J. Tobin, and P. V. Lehmann. 1993. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 366:69.
-
(1993)
Nature
, vol.366
, pp. 69
-
-
Kaufman, D.L.1
Clare-Salzler, M.2
Tian, J.3
Forsthuber, T.4
Ting, G.S.5
Robinson, P.6
Atkinson, M.A.7
Sercarz, E.E.8
Tobin, A.J.9
Lehmann, P.V.10
-
3
-
-
0029093933
-
The role of IL-12 in the induction of organ-specific autoimmune diseases
-
Trembleau, S., T. Germann, M. K. Gately, and L. Adorini. 1995. The role of IL-12 in the induction of organ-specific autoimmune diseases. Immunol. Today 16:383.
-
(1995)
Immunol. Today
, vol.16
, pp. 383
-
-
Trembleau, S.1
Germann, T.2
Gately, M.K.3
Adorini, L.4
-
5
-
-
0031452948
-
Determinant spreading of T helper 2 (Th2) responses to pancreatic islet autoantigens
-
Tian, J., P. V. Lehmann, and D. L. Kaufman. 1997. Determinant spreading of T helper 2 (Th2) responses to pancreatic islet autoantigens. J. Exp. Med. 186:2039.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 2039
-
-
Tian, J.1
Lehmann, P.V.2
Kaufman, D.L.3
-
6
-
-
0027166935
-
Determinant spreading and the dynamics of the autoimmune T-cell repertoire
-
Lehmann, P. V., E. E. Sercarz, T. Forsthuber, C. M. Dayan, and G. Gammon. 1993. Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunol. Today 14:203.
-
(1993)
Immunol. Today
, vol.14
, pp. 203
-
-
Lehmann, P.V.1
Sercarz, E.E.2
Forsthuber, T.3
Dayan, C.M.4
Gammon, G.5
-
7
-
-
0027908753
-
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
-
Tisch, R., X. D. Yang, S. M. Singer, R. S. Liblau, L. Fugger, and H. O. McDevitt. 1993. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366:72.
-
(1993)
Nature
, vol.366
, pp. 72
-
-
Tisch, R.1
Yang, X.D.2
Singer, S.M.3
Liblau, R.S.4
Fugger, L.5
McDevitt, H.O.6
-
8
-
-
0029975898
-
A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: A basis for peptide-specific therapy after onset of clinical disease
-
Yu, M., J. M. Johnson, and V. K. Tuohy. 1996. A predictable sequential determinant spreading cascade invariably accompanies progression of experimental autoimmune encephalomyelitis: a basis for peptide-specific therapy after onset of clinical disease. J. Exp. Med. 183:1777.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1777
-
-
Yu, M.1
Johnson, J.M.2
Tuohy, V.K.3
-
9
-
-
0031785620
-
Infectious Th1 and Th2 immunity in diabetes prone mice
-
Tian, J., A. P. Olcott, L. R. Hanssen, D. Zekzer, B. Middleton, and D. L. Kaufman. 1998. Infectious Th1 and Th2 immunity in diabetes prone mice. Immunol. Rev. 164:119.
-
(1998)
Immunol. Rev.
, vol.164
, pp. 119
-
-
Tian, J.1
Olcott, A.P.2
Hanssen, L.R.3
Zekzer, D.4
Middleton, B.5
Kaufman, D.L.6
-
10
-
-
0025995510
-
A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis
-
Smilek, D. E., D. C. Wraith, S. Hodgkinson, S. Dwivedy, L. Steinman, and H. O. McDevitt. 1991. A single amino acid change in a myelin basic protein peptide confers the capacity to prevent rather than induce experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 88:9633.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 9633
-
-
Smilek, D.E.1
Wraith, D.C.2
Hodgkinson, S.3
Dwivedy, S.4
Steinman, L.5
McDevitt, H.O.6
-
11
-
-
0027954364
-
Antigen-specific immunotherapy: Is it a real possibility to combat T-cell-mediated autoimmunity?
-
Tisch, R., and H. O. McDevitt. 1994. Antigen-specific immunotherapy: is it a real possibility to combat T-cell-mediated autoimmunity? Proc. Natl. Acad. Sci. USA 91:437.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 437
-
-
Tisch, R.1
McDevitt, H.O.2
-
12
-
-
16144361909
-
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice
-
Tian, J., M. Clare-Salzler, A. Herschenfeld, B. Middleton, D. Newman, R. Mueller, S. Arita, C. Evans, M. A. Atkinson, Y. Mullen, N. Sarvetnick, A. J. Tobin, P. V. Lehmann, and D. L. Kaufman. 1996. Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice. Nat. Med. 2:1348.
-
(1996)
Nat. Med.
, vol.2
, pp. 1348
-
-
Tian, J.1
Clare-Salzler, M.2
Herschenfeld, A.3
Middleton, B.4
Newman, D.5
Mueller, R.6
Arita, S.7
Evans, C.8
Atkinson, M.A.9
Mullen, Y.10
Sarvetnick, N.11
Tobin, A.J.12
Lehmann, P.V.13
Kaufman, D.L.14
-
13
-
-
0030472449
-
Manipulation of the Th1/Th2 balance in autoimmune disease
-
Nicholson, L. B., and V. K. Kuchroo. 1996. Manipulation of the Th1/Th2 balance in autoimmune disease. Curr. Opin. Immunol. 8:837.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 837
-
-
Nicholson, L.B.1
Kuchroo, V.K.2
-
14
-
-
0029965137
-
A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: A tale of smart bombs and the infantry
-
Steinman, L. 1996. A few autoreactive cells in an autoimmune infiltrate control a vast population of nonspecific cells: a tale of smart bombs and the infantry. Proc. Natl. Acad. Sci. USA 93:2253.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2253
-
-
Steinman, L.1
-
15
-
-
0030847054
-
Oral tolerance: Immune mechanisms and treatment of autoimmune diseases
-
Weiner, H. L. 1997. Oral tolerance: immune mechanisms and treatment of autoimmune diseases. Immunol. Today 18:335.
-
(1997)
Immunol. Today
, vol.18
, pp. 335
-
-
Weiner, H.L.1
-
16
-
-
3643082454
-
Antigen-based immunotherapy for autoimmune disease: From animal models to man?
-
In press
-
Tian, J., A. P. Olcott, L. R. Hanssen, D. Zekzer, and D. L. Kaufman. 1998. Antigen-based immunotherapy for autoimmune disease: from animal models to man? Immunol. Today. In press.
-
(1998)
Immunol. Today
-
-
Tian, J.1
Olcott, A.P.2
Hanssen, L.R.3
Zekzer, D.4
Kaufman, D.L.5
-
17
-
-
0028982517
-
Th1 and Th2 subsets: Paradigms lost?
-
Kelso, A. 1995. Th1 and Th2 subsets: paradigms lost? Immunol. Today 16:374.
-
(1995)
Immunol. Today
, vol.16
, pp. 374
-
-
Kelso, A.1
-
18
-
-
0029928417
-
The expanding universe of T-cell subsets: Th1, Th2 and more
-
Mosmann, T. R., and S. Sad. 1996. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today 17:138.
-
(1996)
Immunol. Today
, vol.17
, pp. 138
-
-
Mosmann, T.R.1
Sad, S.2
-
19
-
-
0030746897
-
Th1-Th2: Reliable paradigm or dangerous dogma?
-
Allen, J. E., and R. M. Maizels. 1997. Th1-Th2: Reliable paradigm or dangerous dogma? Immunol. Today 18:387.
-
(1997)
Immunol. Today
, vol.18
, pp. 387
-
-
Allen, J.E.1
Maizels, R.M.2
-
20
-
-
0028215907
-
Peptide therapy for diabetes in NOD mice
-
Elias, D., and I. R. Cohen. 1994. Peptide therapy for diabetes in NOD mice. Lancet 343:704.
-
(1994)
Lancet
, vol.343
, pp. 704
-
-
Elias, D.1
Cohen, I.R.2
-
21
-
-
0030293682
-
Suppression of murine chronic relapsing experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein
-
Meyer, A. L., J. M. Benson, I. E. Gienapp, K. L. Cox, and C. C. Whitacre. 1996. Suppression of murine chronic relapsing experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. J. Immunol. 157:4230.
-
(1996)
J. Immunol.
, vol.157
, pp. 4230
-
-
Meyer, A.L.1
Benson, J.M.2
Gienapp, I.E.3
Cox, K.L.4
Whitacre, C.C.5
-
22
-
-
0030069688
-
Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
-
Daniel, D., and D. R. Wegmann. 1996. Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc. Natl. Acad. Sci. USA 93:956.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 956
-
-
Daniel, D.1
Wegmann, D.R.2
-
23
-
-
0028861576
-
Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription
-
Muir, A., A. Peck, M. Clare-Salzler, Y. H. Song, J. Cornelius, R. Luchetta, J. Krischer, and N. Maclaren. 1995. Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription. J. Clin. Invest. 95:628.
-
(1995)
J. Clin. Invest.
, vol.95
, pp. 628
-
-
Muir, A.1
Peck, A.2
Clare-Salzler, M.3
Song, Y.H.4
Cornelius, J.5
Luchetta, R.6
Krischer, J.7
Maclaren, N.8
-
24
-
-
0029670540
-
Induction of TH1 and TH2 immunity in neonatal mice
-
Forsthuber, T., H. C. Yip, and P. V. Lehmann. 1996. Induction of TH1 and TH2 immunity in neonatal mice. Science 271:1728.
-
(1996)
Science
, vol.271
, pp. 1728
-
-
Forsthuber, T.1
Yip, H.C.2
Lehmann, P.V.3
-
25
-
-
0024353079
-
TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
-
Mosmann, T. R., and R. L. Coffman. 1989. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu. Rev. Immunol. 7:145.
-
(1989)
Annu. Rev. Immunol.
, vol.7
, pp. 145
-
-
Mosmann, T.R.1
Coffman, R.L.2
-
26
-
-
0023663430
-
T cell tolerance by clonal elimination in the thymus
-
Kappler, J. W., N. Roehm, and P. Marrack. 1987. T cell tolerance by clonal elimination in the thymus. Cell 49:273.
-
(1987)
Cell
, vol.49
, pp. 273
-
-
Kappler, J.W.1
Roehm, N.2
Marrack, P.3
-
27
-
-
0027509812
-
+ T cell subset that inhibits this autoimmune potential
-
+ T cell subset that inhibits this autoimmune potential. J. Exp. Med. 177:627.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 627
-
-
Fowell, D.1
Mason, D.2
-
28
-
-
0028409436
-
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity
-
Scott, B., R. Liblau, S. Degermann, L. A. Marconi, L. Ogata, A. J. Caton, H. O. McDevitt, and D. Lo. 1994. A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity 1:73.
-
(1994)
Immunity
, vol.1
, pp. 73
-
-
Scott, B.1
Liblau, R.2
Degermann, S.3
Marconi, L.A.4
Ogata, L.5
Caton, A.J.6
McDevitt, H.O.7
Lo, D.8
-
29
-
-
0027968081
-
Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels
-
Oehen, S. U., P. S. Ohashi, K. Burki, H. Hengartner, R. M. Zinkernagel, and P. Aichele. 1994. Escape of thymocytes and mature T cells from clonal deletion due to limiting tolerogen expression levels. Cell. Immunol. 158:342.
-
(1994)
Cell. Immunol.
, vol.158
, pp. 342
-
-
Oehen, S.U.1
Ohashi, P.S.2
Burki, K.3
Hengartner, H.4
Zinkernagel, R.M.5
Aichele, P.6
-
30
-
-
0028763712
-
Levels of peripheral T cell tolerance induced by different doses of tolerogen
-
Ferber, I., G. Schonrich, J. Schenkel, A. L. Mellor, G. J. Hammerling, and B. Arnold. 1994. Levels of peripheral T cell tolerance induced by different doses of tolerogen. Science 263:674.
-
(1994)
Science
, vol.263
, pp. 674
-
-
Ferber, I.1
Schonrich, G.2
Schenkel, J.3
Mellor, A.L.4
Hammerling, G.J.5
Arnold, B.6
-
31
-
-
0028824098
-
Low avidity recognition of self-antigen by T cells permits escape from central tolerance
-
Liu, G. Y., P. J. Fairchild, R. M. Smith, J. R. Prowle, D. Kioussis, and D. C. Wraith. 1995. Low avidity recognition of self-antigen by T cells permits escape from central tolerance. Immunity 3:407.
-
(1995)
Immunity
, vol.3
, pp. 407
-
-
Liu, G.Y.1
Fairchild, P.J.2
Smith, R.M.3
Prowle, J.R.4
Kioussis, D.5
Wraith, D.C.6
-
32
-
-
0026572986
-
Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants
-
Cibotti, R., J. M. Kanellopoulos, J. P. Cabaniols, O. Halle-Panenko, K. Kosmatopoulos, E. Sercarz, and P. Kourilsky. 1992. Tolerance to a self-protein involves its immunodominant but does not involve its subdominant determinants. Proc. Natl. Acad. Sci. USA 89:416.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 416
-
-
Cibotti, R.1
Kanellopoulos, J.M.2
Cabaniols, J.P.3
Halle-Panenko, O.4
Kosmatopoulos, K.5
Sercarz, E.6
Kourilsky, P.7
-
33
-
-
0027940262
-
Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen
-
Zal, T., A. Volkmann, and B. Stockinger. 1994. Mechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen. J. Exp. Med. 180:2089.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2089
-
-
Zal, T.1
Volkmann, A.2
Stockinger, B.3
-
34
-
-
0028446546
-
How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model
-
von Herrath, M. G., J. Dockter, and M. B. Oldstone. 1994. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model. Immunity 1:231.
-
(1994)
Immunity
, vol.1
, pp. 231
-
-
Von Herrath, M.G.1
Dockter, J.2
Oldstone, M.B.3
-
35
-
-
0030852519
-
A range of CD4 T cell tolerance: Partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis
-
Akkaraju, S., W. Y. Ho, D. Leong, K. Canaan, M. M. Davis, and C. C. Goodnow. 1997. A range of CD4 T cell tolerance: partial inactivation to organ-specific antigen allows nondestructive thyroiditis or insulitis. Immunity 7:255.
-
(1997)
Immunity
, vol.7
, pp. 255
-
-
Akkaraju, S.1
Ho, W.Y.2
Leong, D.3
Canaan, K.4
Davis, M.M.5
Goodnow, C.C.6
-
36
-
-
18244421874
-
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes
-
Pugliese, A., M. Zeller, A. Fernandez, Jr., L. J. Zalcberg, R. J. Bartlett, C. Ricordi, M. Pietropaolo, G. S. Eisenbarth, S. T. Bennett, and D. D. Patel. 1997. The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. Nat. Genet. 15:293.
-
(1997)
Nat. Genet.
, vol.15
, pp. 293
-
-
Pugliese, A.1
Zeller, M.2
Fernandez Jr., A.3
Zalcberg, L.J.4
Bartlett, R.J.5
Ricordi, C.6
Pietropaolo, M.7
Eisenbarth, G.S.8
Bennett, S.T.9
Patel, D.D.10
-
37
-
-
0030452309
-
Late complications of immune deviation therapy in a nonhuman primate
-
Genain, C. P., K. Abel, N. Belmar, F. Villinger, D. P. Rosenberg, C. Linington, C. S. Raine, and S. L. Hauser. 1996. Late complications of immune deviation therapy in a nonhuman primate. Science 274:2054.
-
(1996)
Science
, vol.274
, pp. 2054
-
-
Genain, C.P.1
Abel, K.2
Belmar, N.3
Villinger, F.4
Rosenberg, D.P.5
Linington, C.6
Raine, C.S.7
Hauser, S.L.8
-
38
-
-
0027176158
-
Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes
-
Harrison, L. C., M. C. Honeyman, H. J. DeAizpurua, R. S. Schmidli, P. G. Colman, B. D. Tait, and D. S. Cram. 1993. Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes. Lancet 341:1365.
-
(1993)
Lancet
, vol.341
, pp. 1365
-
-
Harrison, L.C.1
Honeyman, M.C.2
DeAizpurua, H.J.3
Schmidli, R.S.4
Colman, P.G.5
Tait, B.D.6
Cram, D.S.7
-
39
-
-
0029923430
-
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
-
Tian, J., M. A. Atkinson, M. Clare-Salzler, A. Herschenfeld, T. Forsthuber, P. V. Lehmann, and D. L. Kaufman. 1996. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J. Exp. Med. 183:1561.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1561
-
-
Tian, J.1
Atkinson, M.A.2
Clare-Salzler, M.3
Herschenfeld, A.4
Forsthuber, T.5
Lehmann, P.V.6
Kaufman, D.L.7
-
40
-
-
0030960632
-
Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and down-regulates autoimmunity to various beta-cell antigens
-
Elias, D., A. Meilin, V. Ablamunits, O. S. Birk, P. Carmi, S. Konen-Waisman, and I. R. Cohen. 1997. Hsp60 peptide therapy of NOD mouse diabetes induces a Th2 cytokine burst and down-regulates autoimmunity to various beta-cell antigens. Diabetes 46:758.
-
(1997)
Diabetes
, vol.46
, pp. 758
-
-
Elias, D.1
Meilin, A.2
Ablamunits, V.3
Birk, O.S.4
Carmi, P.5
Konen-Waisman, S.6
Cohen, I.R.7
-
41
-
-
0030879734
-
Mechanism underlying counterregulation of autoimmune diabetes by IL-4
-
Mueller, R., L. M. Bradley, T. Krahl, and N. Sarvetnick. 1997. Mechanism underlying counterregulation of autoimmune diabetes by IL-4. Immunity 7:411.
-
(1997)
Immunity
, vol.7
, pp. 411
-
-
Mueller, R.1
Bradley, L.M.2
Krahl, T.3
Sarvetnick, N.4
|