Evidence for a major gene for type II diabetes and linkage analyses with selected candidate genes in Mexican-Americans

Diabetes

Volumn 45, Issue 5, 1996, Pages 563-568

  Stern, Michael P ^a,d   Mitchell, Braxton D ^b   Blangero, John ^b   Reinhart, Laurie ^a   Kammerer, Candace M ^b   Harrison, Chantal R ^a   Shipman, Patricia A ^a   O'Connell, Peter ^a   Frazier, Marsha L ^c   MacCluer, Jean W ^b  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH   (United States)

^c UNIVERSITY OF TEXAS   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DEAMINASE; CHOLESTEROL; DNA; FATTY ACID BINDING PROTEIN; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; INSULIN RECEPTOR; LIPID; LIPOPROTEIN; LIPOPROTEIN LIPASE; LYMPHOTOXIN; ORAL ANTIDIABETIC AGENT; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR RECEPTOR;

ADULT; ALLELE; ARTICLE; BLOOD GROUP RHESUS SYSTEM; BODY MASS; DIASTOLIC BLOOD PRESSURE; ETHNIC GROUP; GENE FREQUENCY; GENETIC LINKAGE; GENOTYPE; HUMAN; HUMAN CELL; INHERITANCE; MAJOR CLINICAL STUDY; MAJOR GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; ORAL DRUG ADMINISTRATION; PEDIGREE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 15844429514     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.45.5.563     Document Type: Article

References (44)

1. Newman B, Selby JV, King ML, Slemenda C, Fabsitz R, Friedman GD: Concordance for type 2 (non-insulin dependent) diabetes mellitus in male twins. Diabetologia 30:763-769, 1987
2. Barnett AH, Eff C, Leslie RDG, Pyke DA. Diabetes in identical twins: a study of 200 pairs. Diabetologia 20:87-93, 1981
3. West KM: Epidemiology of Diabptes and Its Vascular Lesions. New York, Elsevier, 1978, p. 199-201
4. Stern MP, Rosenthal M, Haffner SM, Hazuda HP, Franco LJ: Sex difference in the effects of sociocultural status on diabetes and cardiovascular risk factors in Mexican Americans: the San Antonio Heart Study. Am J Epidemiol 120:834-851, 1984
5. Zimmet P: Epidemiology of diabetes and its macrovascular complications in Pacific populations: the medical effects of social progress. Diabetes Care 2:144-153, 1979
6. Jackson WPU: Epidemiology of diabetes in South Africa. Adv Metab Disurd 9:111-146, 1978
7. Gardner LI, Stern MP, Haffner SM, Gaskill SP, Hazuda HP, Relethford JH, Eifler CW: Prevalence of diabetes in Mexican Americans: relationship to percent of gene pool derived from native American sources. Diabetes 33:86-92, 1984
8. Chakraborty R, Ferrell RE, Stern MP, Haffner SM, Hazuda HP, Rosenthal M: Relationship of prevalence of non-insulin dependent diabetes mellitus to Amerindian admixture in the Mexican Americans of San Antonio, Texas. Genet Epidemiol 3:435-454, 1986
9. Serjeantson SW, Owerbach D, Zimmet P, Nerup J, Thoma K: Genetics of diabetes in Nauru: effects of foreign admixture, HLA antigens and the insulin-gene-linked polymorphism. Diabetologia 25:13-17, 1983
10. Brosseau JD, Eelkema RC, Crawford AC, Abe TA: Diabetes among the three affiliated tribes: correlation with degree of Indian inheritance. Am J Public Health 69:1277-1278, 1979
11. Knowler WC, Williams RC, Pettitt DJ, Steinberg AF: Gm3,7,13,14 and type 2 diabetes mellitus: an association in American Indians with genetic admixture. Am J Hum Genet 43:520-526, 1988
12. World Health Organization Expert Committee: Diabetes Mellitus: Report of a WHO Study Group Geneva, World Health Organization, 1985 (Tech. Rep. Ser. no. 727)
13. Hazuda HP, Comeaux PJ, Stern MP, Haffner SM, Eifler CW, Rosenthal M: A comparison of three indicators for identifying Mexican Americans in epidemiologic research: methodologic findings from the San Antonio Heart Study. Am J Epidemiol 123.96-112, 1986
14. Stern MP, Patterson JK, Haffner SM, Hazuda HP, Mitchell BD: Lack of awareness and treatment of hyperlipidemia in type II diabetes in a community survey. JAMA 262:360-364, 1989
15. Stern MP, Morales PA, Valdez RA, Monterrosa A, Haffner SM, Mitchell BD, Hazuda HP: Predicting diabetes: moving beyond impaired glucose tolerance. Diabetes 42:706-714, 1993
16. Stern MP, Haffner SM. Type II diabetes and its complications in Mexican Americans. Diabetes Metab Rev 6:29-45, 1990
17. S.A.G.E. Statistical Analysis for Genetic Epidemiology. Release 2 2. New Orleans, Department of Biometry and Genetics, Louisiana State Univ. Medical Center, 1994
18. Bonney GE: Regressive logistic models for familial disease and other binary traits. Biometrics 42:611-625, 1986
19. Elston RC, George VT: Age of onset, age at examination and other covariates in the analysis of family data. Genet Epidemiol 6:217-220, 1989
20. Elston RC, Namboodiri KK, Spence MA, Rainer JD: A genetic study of schizophrenia in pedigrees. II. One locus hypotheses. Neuropsychobiology 4:193-206, 1978
21. Cherif-Zahar B, Mattei MG, Le Van KC, Bailly P, Cartron JP, Colin Y. Localization of the human Rh blood group gene structure to chromosome region 1p34 3-1p36.1 by in situ hybridization Hum Genet 86:398-400, 1991
22. Hanis CL, Bertin TK: Juxtaposed short sequence repeat types and haplotypes near exon 3 of the insulin receptor locus among Mexican Americans. Genomics 12:842-845, 1992
23. Hixson JE, Kammerer CM, Cox LA, Mott GE: Identification of LDL receptor gene marker associated with altered levels of LDL cholesterol and apolipoprotein B in baboons Arteriosclerosis 9:829-835, 1989
24. Kaufman BA, White PH, Brodeur G: A complex single strand conformational polymorphism (SSCP) in the tumor necrosis factor receptor 2 (TNFR2) gene on chromosome 1p36.2. Hum Mol Genet 2.824, 1993
25. Stoffel M, Espinosa R, Keller SH, Lienhard GE, Le Beau MM, Bell GI: Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q30 1 and identification of a single tandem repeat DNA polymorphism. Diabetologia 36:335-337, 1993
26. Froguel P, Zouali H, Sun F, Velho G, Fukumoto H, Passa P, Cohen D: CA repeat polymorphism in the glucose transporter GLUT2 gene. Nucleic Acids Res 19:3754, 1991
27. Prochazka M, Lillioja S, Tait JF, Knowler WC, Mott DM, Spraul M, Bennett PH, Bogardus C: Linkage of chromosomal markers on 4q with a putative gene determining maximal insulin action in Pima Indians. Diabetes 42:514-519, 1993
28. Baier LJ, Sacchettini JC, Knowler WC, Eads J, Paolisso G, Tatarinni PA, Mochizuki H, Bennett PH, Bogardus C, Prochazka M: An amino acid substitution in the human intestinal fatty acid binding protein is associated with increased fatty acid binding, increased fat oxidation, and insulin resistance J Clin Invest 95:1281-1287, 1995
29. Nedospasov SA, Udalova IA, Kuprash DV, Turetskaya RL: A sequence polymorphism at the human tumor necrosis factor (TNF) locus: numerous TNF lymphotoxin alleles tagged by two closely linked microsatellites in the upstream region of the lymphotoxin (TNF-β) gene. J Immunol 147:1053-1059, 1991
30. Froguel P, Vaxillaire M, Sun F, Velho G, Zouali H, Butel MO, Lesage S, Vionnet N, Clement K, Fougerousse F, Tanizawa Y, Weissenbach J, Beckmann JS, Lathrop GM, Passa P, Permutt MA, Cohen D: Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin dependent diabetes mellitus. Nature 356:162-164, 1992
31. Zuliani G, Hobbs HH Tetranucleotide repeat polymorphism in the LPL gene. Nucleic Acids Res 18:4958, 1990
32. Hanis CL, Bertin TK: Identification of an insulin receptor exon 8 Nsi I polymorphism using the polymerase chain reaction. Nucleic Acids Res 18:5923, 1990
33. Bell GI, Xiang K-S, Newman MV, Wu S, Wright LG, Fajans SS, Spielman RS, Cox NJ. The gene for noninsulin-dependent diabetes mellilus (maturity onset diabetes of the young subtype) is linked to DNA polymorphism on human chromosome 20q Proc Natl Acad Sci USA 88:1484-1488, 1991
34. Mitchell BD, Kammerer CM, Reinhart LJ, Stern MP: NIDDM in Mexican-American families: heterogeneity by age of onset. Diabetes Care 17.567-573, 1994
35. Ploughman LM, Boehnke M: Estimating the power of a proposed linkage study for a complex genetic trait. Am J Hum Genet 44:543-551, 1989
36. Mitchell BD, Kammerer CM, O'Connell P, Harrison CR, Manire M, Shipman P, Moyer MP, Stern MP, Frazier ML: Evidence for linkage of postchallenge insulin levels with intestinal fatty acid binding protein (FABP2) in Mexican Americans. Diabetes 44:1046-1053, 1995
37. Hanson RL, Elston RC, Pettitt DJ, Bennett PH, Knowler WC: Segregation analysis of non-insulin dependent diabetes mellitus in Pima Indians: evidence for a major gene effect Am J Hum Genet 57:160-170, 1993
38. Serjeantson S, Zimmet P. Diabetes in the Pacific: evidence for a major gene. In Diabetes Mellitus. Recent Knowledge on Etiology, Complications and Treatment. Baba S, Gould MK, Zimmet P, Eds. Sydney, Academic Press Australia, 1984, p. 23-30
39. Elston RC, Namboodiri KK, Nino HV, Pollitzer WS Studies on blood and urine glucose in Semmole Indians, indications for segregation of a major gene. Am J Hum Genet 26:13-34, 1974
40. Zimmet P, Dowse G, Finch C, Serjeantson S, King H: The epidemiology and natural history of NIDDM: lessons from the South Pacific. Diabetes Metab Rev 6:91-124, 1990
41. Knowler WC, Pettitt DJ, Saad MF, Bennett PH: Diabetes mellitus in the Pima Indians: incidence, risk factors and pathogenesis. Diabetes Metab Rev 6:1-27, 1990
42. King H, Rewers M, WHO Ad Hoc Diabetes Reporting Group: Global estimates for prevalence of diabetes mellitus and impaired glucose tolerance in adults Diabetes Care 16:157-177, 1993
43. US Bureau of the Census: Current Population Reports, Scries P-20, No. 455. The Hispanic Population of the United States: March 1991. Washington, DC, U.S. Govt. Printing Office, 1991
44. King H, Rewers M, on behalf of the WHO Ad Hoc Diabetes Reporting Group: Diabetes in adults is now a third world problem. Bull WHO 69:643-648, 1991