Mechanism-based inactivation of P450 2A6 by furanocoumarins

Biochemistry

Volumn 37, Issue 28, 1998, Pages 10047-10061

  Koenigs, Luke L ^a   Trager, William F ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; FUROCOUMARIN; METHOXSALEN;

ARTICLE; ENZYME ACTIVITY; EPOXIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DETERMINATION; RADIOMETRY; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROPHOTOMETRY;

ARYL HYDROCARBON HYDROXYLASES; BINDING SITES; CARBON RADIOISOTOPES; COUMARINS; CYTOCHROME P-450 ENZYME SYSTEM; DEUTERIUM OXIDE; ENZYME ACTIVATION; HUMANS; METHOXSALEN; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; OXYGEN ISOTOPES;

EID: 0032516469     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980003c     Document Type: Article

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