Mechanism-based inactivation of cytochrome P450 2B1 by N-benzyl-1- aminobenzotriazole

Chemical Research in Toxicology

Volumn 10, Issue 5, 1997, Pages 600-608

  Kent, Ute M ^a   Bend, John R ^b   Chamberlin, Beverly A ^c   Gage, Douglas A ^c   Hollenberg, Paul F ^a,d  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

^c Michigan State University   (United States)

^d 1560 Med Science Research Bldg II   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 ETHOXYCOUMARIN DEETHYLASE; BENZENE DERIVATIVE; CYTOCHROME P450; GLUTATHIONE; TRIAZOLE DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; ENZYME INACTIVATION; ENZYME POLYMORPHISM; ENZYME PURIFICATION; ENZYME SUBSTRATE; LIVER MICROSOME; MALE; NONHUMAN; RAT; XENOBIOTIC METABOLISM;

ANIMALS; APOPROTEINS; COUMARINS; CYTOCHROME P-450 CYP2B1; IODOBENZENES; KINETICS; LIVER; MALE; PROTEIN BINDING; RATS; RATS, INBRED STRAINS; SUBSTRATE SPECIFICITY; TRIAZOLES;

ANIMALIA;

EID: 0030923680     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx960184o     Document Type: Article

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