Identification of amino acid residues responsible for differences in substrate specificity and inhibitor sensitivity between two human liver dihydrodiol dehydrogenase isoenzymes by site-directed mutagenesis

Biochemical Journal

Volumn 323, Issue 1, 1997, Pages 61-64

  Matsuura, Kazuya ^a   Deyashiki, Yoshihiro ^a   Sato, Kumiko ^a   Ishida, Naoko ^a   Miwa, Gunpei ^a   Hara, Akira ^a  

^a GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

1,10 PHENANTHROLINE; 20ALPHA HYDROXYSTEROID DEHYDROGENASE; AMINO ACID; ARGININE; CYSTEINE; DIHYDRODIOL DEHYDROGENASE; GLUTAMINE; HISTIDINE; ISOENZYME; LEUCINE; LIVER ENZYME; METHIONINE; SERINE; THREONINE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME SPECIFICITY; HUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0030907884     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/bj3230061     Document Type: Article

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