Adaptation to promiscuous usage of CC and CXC-chemokine coreceptors in vivo correlates with HIV-1 disease progression

AIDS

Volumn 12, Issue 13, 1998, Pages

  Xiao, Lihua ^a   Rudolph, Donna L ^a   Owen, Sherry M ^a   Spira, Thomas J ^a   Lal, Renu B ^a,b  

^a U S DEPARTMENT OF HEALTH AND HUMAN SERVICES   (United States)

^b HIV/Retrovirus Diseases Branch   (United States)

Author keywords

Pathogenesis; Receptor; Virus cell interaction

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PHYTOHEMAGGLUTININ; RANTES;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LEUKOCYTE COUNT; MALE; MONONUCLEAR CELL; PATHOGENESIS; PRIORITY JOURNAL; VIRUS REPLICATION;

ADAPTATION, PHYSIOLOGICAL; CELL LINE; CHEMOKINES, CC; COHORT STUDIES; DISEASE PROGRESSION; GTP-BINDING PROTEINS; HIV SEROPOSITIVITY; HIV-1; HOMOSEXUALITY, MALE; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; RANTES; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; RECEPTORS, CXCR4; RECEPTORS, CYTOKINE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HIV; RECEPTORS, PEPTIDE;

EID: 0032505013     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-199813000-00001     Document Type: Article

References (24)

1. Fauci AS: Host factors and the pathogenesis of HIV-induced disease. Nature 1996, 384:529-534.
2. Haynes BF, Pantaleo G, Fauci AS: Toward an understanding of the correlates of protective immunity to HIV infection. Science 1996, 271:324-328.
3. Coffin JM: HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 1996, 267:483-489.
4. Wolinsky SM, Korber BT, Neumann AU, et al.: Adaptive evolution of human immunodeficiency virus-type 1 during the natural course of infection. Science 1996, 272:537-542.
5. Berger EA: HIV entry and tropism: the chemokine receptor connection. AIDS 1997, 11 (suppl A):S3-S16.
6. Dittmar MT, McKnight A, Simmons G, Clapham PR, Weiss R, Simmonds P: HIV-1 tropism and coreceptor use. Nature 1996, 385:496-497.
7. Choe H, Farzan M, Sun Y, et al.: The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996, 85:1135-1148.
8. Deng HK, Unutmaz D, KewalRamani VN, Littman DR: Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature 1997, 388:296-300.
9. Connor RI, Sheridan KE, Ceradini D, Choe S, Landau NR: Change in coreceptor use correlates with disease progression in HIV-1 infected individuals. J Exp Med 1997, 185:621-628.
10. Fishbein, DB, Kaplan JE, Spira TJ, et al.: Unexplained lymphadenopathy in homosexual men. JAMA 1985, 254:930-935.
11. Xiao L, Owen SM, Goldman I, et al.: CCR5-coreceptor usage of non-syncytium-inducing primary HIV-1 is independent of phylogenetically distinct global HIV-1 isolates: delineation of consensus motif in the V3 domain that predicts CCR-5 usage. Virology 1998, 240:83-92.
12. Owen SM, Ellenberger D, Rayfield M, et al.: Genetically divergent strains of human immunodeficiency virus type 2 use multiple coreceptors for viral entry. J Virol 1998, 72:5425-5432.
13. Liu R, Paxton WA, Choe S, et al.: Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection. Cell 1996, 86:367-377.
14. Huang Y, Paxton WA, Wolinsky SM, et al.: The role of a mutant CCR5 allele in HIV-1 transmission and disease progression. Nat Med 1996, 2:1240-1243.
15. Berger EA, Doms RW, Fenyo EM, et al.: A new classification for HIV-1 [letter]. Nature 1998, 391:240.
16. Scarlatti G, Tresoldi E, Bjorndal A, et al.: In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression. Nat Med 1997, 3:1259-1265.
17. Michael NL, Chang G, Louie LG, et al.: The role of viral phenotypes and CCR-5 gene defects in HIV-1 transmission and disease progression. Nat Med 1997, 3:338-340.
18. Carroll RG, Riley JL, Levine BL, et al.: Differential regulation of HIV-1 fusion cofactor expression by CD28 costimulation of CD4+ T cells. Science 1997, 276:273-276.
19. Weissman D, Barker TD, Fauci AS: The efficiency of acute infection of CD4+ T cells is markedly enhanced in the setting of antigen-specific immune activation. J Exp Med 1996, 183:687-692.
20. Michael NL, Louie LG, Rohrbaugh AL, et al.: The role of CCR5 and CCR2 polymorphism in HIV-1 transmission and disease progression. Nat Med 1997, 3:1160-1162.
21. Winkler C, Modi W, Smith MW, et al.: Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant. Science 1998, 279:389-393.
22. Knuchel M, Spira T, Xiao L, et al.: Analysis of a biallelic polymorphism in the tumor necrosis factor alpha promoter and HIV-1 disease progression. AIDS Res Hum Retroviruses 1998, 14:305-309.
23. Clerici M, Balotta C, Trabattoni D, et al.: Chemokine production in HIV-seropositive long-term asymptomatic individuals. AIDS 1996, 10:1432-1433.
24. Kinter AL, Ostrowski M, Goletti D, et al.: HIV replication in CD4+ T cells of HIV-infected individuals is regulated by a balance between the viral suppressive effects of endogenous β-chemokine and the viral inductive effects of other endogenous cytokines. Proc Natl Acad Sci USA 1996, 93:14076-14081.