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Volumn 271, Issue 5247, 1996, Pages 324-328

Toward an understanding of the correlates of protective immunity to HIV infection

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

EID: 0030593031     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.271.5247.324     Document Type: Article
Times cited : (366)

References (195)
  • 1
    • 0027172407 scopus 로고
    • H W. Sheppard et al , AIDS 7, 1159 (1993); H W Sheppard et al , J. AIDS 4, 704 (1991), J Phair et al., ibid. 5, 490 (1992), J Phair, AIDS Res Hum. Retroviruses 10, 883 (1994), A. Munoz et al, Am J Epidemiol. 130, 530 (1989)
    • (1993) AIDS , vol.7 , pp. 1159
    • Sheppard, H.W.1
  • 2
    • 0026008595 scopus 로고
    • H W. Sheppard et al , AIDS 7, 1159 (1993); H W Sheppard et al , J. AIDS 4, 704 (1991), J Phair et al., ibid. 5, 490 (1992), J Phair, AIDS Res Hum. Retroviruses 10, 883 (1994), A. Munoz et al, Am J Epidemiol. 130, 530 (1989)
    • (1991) J. AIDS , vol.4 , pp. 704
    • Sheppard, H.W.1
  • 3
    • 0026530178 scopus 로고
    • H W. Sheppard et al , AIDS 7, 1159 (1993); H W Sheppard et al , J. AIDS 4, 704 (1991), J Phair et al., ibid. 5, 490 (1992), J Phair, AIDS Res Hum. Retroviruses 10, 883 (1994), A. Munoz et al, Am J Epidemiol. 130, 530 (1989)
    • (1992) J. AIDS , vol.5 , pp. 490
    • Phair, J.1
  • 4
    • 0028131190 scopus 로고
    • H W. Sheppard et al , AIDS 7, 1159 (1993); H W Sheppard et al , J. AIDS 4, 704 (1991), J Phair et al., ibid. 5, 490 (1992), J Phair, AIDS Res Hum. Retroviruses 10, 883 (1994), A. Munoz et al, Am J Epidemiol. 130, 530 (1989)
    • (1994) AIDS Res Hum. Retroviruses , vol.10 , pp. 883
    • Phair, J.1
  • 5
    • 0024397774 scopus 로고
    • H W. Sheppard et al , AIDS 7, 1159 (1993); H W Sheppard et al , J. AIDS 4, 704 (1991), J Phair et al., ibid. 5, 490 (1992), J Phair, AIDS Res Hum. Retroviruses 10, 883 (1994), A. Munoz et al, Am J Epidemiol. 130, 530 (1989)
    • (1989) Am J Epidemiol. , vol.130 , pp. 530
    • Munoz, A.1
  • 6
  • 7
    • 0028337166 scopus 로고    scopus 로고
    • R Koup et al., J. Virol. 68, 4650 (1994), P. Borrow et al , ibid., p. 6103; Y. Yasutomi et al , ibid. 67, 1707 (1993). K. A Reimann et al , ibid. 68, 2362 (1994).
    • (1994) J. Virol. , vol.68 , pp. 4650
    • Koup, R.1
  • 8
    • 0028337166 scopus 로고    scopus 로고
    • R Koup et al., J. Virol. 68, 4650 (1994), P. Borrow et al , ibid., p. 6103; Y. Yasutomi et al , ibid. 67, 1707 (1993). K. A Reimann et al , ibid. 68, 2362 (1994).
    • J. Virol. , pp. 6103
    • Borrow, P.1
  • 9
    • 0027404894 scopus 로고
    • R Koup et al., J. Virol. 68, 4650 (1994), P. Borrow et al , ibid., p. 6103; Y. Yasutomi et al , ibid. 67, 1707 (1993). K. A Reimann et al , ibid. 68, 2362 (1994).
    • (1993) J. Virol. , vol.67 , pp. 1707
    • Yasutomi, Y.1
  • 10
    • 0028210969 scopus 로고
    • R Koup et al., J. Virol. 68, 4650 (1994), P. Borrow et al , ibid., p. 6103; Y. Yasutomi et al , ibid. 67, 1707 (1993). K. A Reimann et al , ibid. 68, 2362 (1994).
    • (1994) J. Virol. , vol.68 , pp. 2362
    • Reimann, K.A.1
  • 11
    • 0027979037 scopus 로고
    • G. Pantaleo et al , Nature 370, 463 (1994).
    • (1994) Nature , vol.370 , pp. 463
    • Pantaleo, G.1
  • 12
    • 0025827529 scopus 로고
    • R E. Phillips et al., ibid 354, 453 (1991), R. Cheynier et al., Cell 78, 373 (1994), S Kalam et al., J Exp. Med. 179, 1261 (1994)
    • (1991) Nature , vol.354 , pp. 453
    • Phillips, R.E.1
  • 13
    • 0027959373 scopus 로고
    • R E. Phillips et al., ibid 354, 453 (1991), R. Cheynier et al., Cell 78, 373 (1994), S Kalam et al., J Exp. Med. 179, 1261 (1994)
    • (1994) Cell , vol.78 , pp. 373
    • Cheynier, R.1
  • 14
    • 0028323247 scopus 로고
    • R E. Phillips et al., ibid 354, 453 (1991), R. Cheynier et al., Cell 78, 373 (1994), S Kalam et al., J Exp. Med. 179, 1261 (1994)
    • (1994) J Exp. Med. , vol.179 , pp. 1261
    • Kalam, S.1
  • 16
    • 0027692154 scopus 로고
    • A. S. Fauci, Science 262, 1011 (1993); M. S Saag, AIDS Res Hum. Retroviruses 10, 887 (1994); J. Levy, Microbiol Rev. 57, 183 (1993).
    • (1993) Science , vol.262 , pp. 1011
    • Fauci, A.S.1
  • 17
    • 0027991414 scopus 로고
    • A. S. Fauci, Science 262, 1011 (1993); M. S Saag, AIDS Res Hum. Retroviruses 10, 887 (1994); J. Levy, Microbiol Rev. 57, 183 (1993).
    • (1994) AIDS Res Hum. Retroviruses , vol.10 , pp. 887
    • Saag, M.S.1
  • 18
    • 0027531918 scopus 로고
    • A. S. Fauci, Science 262, 1011 (1993); M. S Saag, AIDS Res Hum. Retroviruses 10, 887 (1994); J. Levy, Microbiol Rev. 57, 183 (1993).
    • (1993) Microbiol Rev. , vol.57 , pp. 183
    • Levy, J.1
  • 19
    • 4243150395 scopus 로고
    • 7 to 12 August Yokohama, Japan, abstr Ps2
    • A. S Fauci et al., 10th International Conference on AIDS, 7 to 12 August 1994, Yokohama, Japan, vol. 10(1), p 4, abstr Ps2.
    • (1994) 10th International Conference on AIDS , vol.10 , Issue.1 , pp. 4
    • Fauci, A.S.1
  • 20
    • 85057350470 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1984) Lancet , vol.2 , pp. 370
    • Armstrong, J.A.1    Home, R.2
  • 21
    • 0022558808 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1986) Prog Allergy , vol.37 , pp. 81
    • Racz, P.1
  • 22
    • 0022551055 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1986) Am. J Pathol. , vol.123 , pp. 9
    • Tenner-Racz, K.1
  • 23
    • 4243065950 scopus 로고    scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • Am. J Pathol. , pp. 436
    • Biberfeld, P.1
  • 24
    • 0022597172 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1986) Histopathology , vol.10 , pp. 5
    • Baroni, L.D.1
  • 25
    • 0026601248 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1992) Am. J Pathol. , vol.140 , pp. 15
    • Spiegel, H.1
  • 26
    • 0026543981 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1992) J. Virol. , vol.66 , pp. 310
    • Michael, N.L.1
  • 27
    • 0027465119 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1993) J Infect. Dis. , vol.167 , pp. 1008
    • Luzuriaga, K.1
  • 28
    • 0027538456 scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • (1993) Nature , vol.362 , pp. 355
    • Pantaleo, G.1
  • 29
    • 84901967483 scopus 로고    scopus 로고
    • J. A. Armstrong and R. Home, Lancet ii, 370 (1984); P Racz et al., Prog Allergy 37, 81 (1986); K. Tenner-Racz et al., Am. J Pathol. 123, 9 (1986); P Biberfeld et al , ibid., p 436; L. D. Baroni et al., Histopathology 10, 5 (1986), H. Spiegel et al., Am. J Pathol. 140, 15 (1992); N. L Michael et al., J. Virol. 66, 310 (1992), K. Luzuriaga et al., J Infect. Dis. 167, 1008 (1993); G. Pantaleo et al , Nature 362, 355 (1993); J. Embretson et al., ibid., p. 359.
    • Nature , pp. 359
    • Embretson, J.1
  • 30
    • 0022487032 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1986) Froc. Natl Acad Sci. U.S.A. , vol.83 , pp. 772
    • Harper, M.E.1
  • 31
    • 0024536506 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1989) Am. J. Pathol. , vol.134 , pp. 373
    • Ringler, D.J.1
  • 32
    • 0025883036 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1991) AIDS , vol.5 , pp. 1071
    • Devergne, O.1
  • 33
    • 0027936176 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1994) , vol.10 , pp. 863
    • Rosenberg, Y.J.1
  • 34
    • 0028244846 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1994) J. Immunol , vol.153 , pp. 1352
    • Schmitz, J.1
  • 35
    • 0028131579 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1994) Cell , vol.78 , pp. 389
    • Pope, M.1
  • 36
    • 0027764405 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1992) Am. J. Pathol. , vol.142 , pp. 1750
    • Tenner-Racz, K.1
  • 37
    • 0028174298 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1994) AIDS. Res. Hum. Retroviruses , vol.10 , pp. 61
    • Cameron, P.U.1
  • 38
    • 0023814638 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1988) Nature , vol.334 , pp. 530
    • Lanzavecchia, A.1
  • 39
    • 0023676066 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1988) Cell , vol.54 , pp. 561
    • Siliciano, R.1
  • 40
    • 11944249873 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1990) Proc Natl. Acad. Sci U.S.A. , vol.87 , pp. 7727
    • Schnittman, S.M.1
  • 41
    • 0025951616 scopus 로고
    • M E. Harper et al., Froc. Natl Acad Sci. U.S.A. 83, 772 (1986), D. J Ringler et al. Am. J. Pathol. 134, 373 (1989); O. Devergne et al , AIDS 5, 1071 (1991), Y. J. Rosenberg et al , 10, 863 (1994); J. Schmitz et al., J. Immunol 153, 1352 (1994); M. Pope et al., Cell 78, 389 (1994), K Tenner-Racz et al., Am. J. Pathol. 142, 1750 (1992), P. U. Cameron et al., AIDS. Res. Hum. Retroviruses 10, 61 (1994); A. Lanzavecchia et al., Nature 334, 530 (1988); R. Siliciano et al., Cell 54, 561 (1988); S. M. Schnittman et al , Proc Natl. Acad. Sci U.S.A. 87, 7727 (1990), S. M. Schnittman et al., J. Immunol. 147, 2553 (1991).
    • (1991) J. Immunol. , vol.147 , pp. 2553
    • Schnittman, S.M.1
  • 42
    • 0029052478 scopus 로고
    • M. Nowak et al., Nature 375, 606 (1995).
    • (1995) Nature , vol.375 , pp. 606
    • Nowak, M.1
  • 43
    • 0025267919 scopus 로고
    • J Albert et al., AIDS 4, 107 (1990). A V. Gegerfelt et al., Virology 185, 162 (1991); J. P. Moore et al., J Virol 68, 5142 (1994).
    • (1990) AIDS , vol.4 , pp. 107
    • Albert, J.1
  • 44
    • 0025992607 scopus 로고
    • J Albert et al., AIDS 4, 107 (1990). A V. Gegerfelt et al., Virology 185, 162 (1991); J. P. Moore et al., J Virol 68, 5142 (1994).
    • (1991) Virology , vol.185 , pp. 162
    • Gegerfelt, A.V.1
  • 45
    • 0028277886 scopus 로고
    • J Albert et al., AIDS 4, 107 (1990). A V. Gegerfelt et al., Virology 185, 162 (1991); J. P. Moore et al., J Virol 68, 5142 (1994).
    • (1994) J Virol , vol.68 , pp. 5142
    • Moore, J.P.1
  • 46
    • 0026444130 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1992) J. AIDS , vol.5 , pp. 1158
    • Kohler, H.1
  • 47
    • 0001420372 scopus 로고
    • S. S. B. Morse, Ed. Raven, New York
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1994) The Evolutionary Biology of Retroviruses , pp. 185-209
    • Wain-Hobson, S.1
  • 48
    • 0028985666 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1995) AIDS Res. Hum Retroviruses , vol.11 , pp. 211
    • Haynes, B.F.1
  • 49
    • 4243052400 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1995) Immunol. Today , vol.16 , pp. 67
    • Fust, G.1
  • 50
    • 0029105368 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1995) Immunologist , vol.3 , pp. 32
    • Kohler, H.1
  • 51
    • 0025804179 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1991) AIDS , vol.5 , pp. 513
    • Montefion, D.C.1
  • 52
    • 0027879388 scopus 로고
    • H Kohler et al , J. AIDS 5, 1158 (1992), S. Wain-Hobson, in The Evolutionary Biology of Retroviruses, S. S. B. Morse, Ed. (Raven, New York, 1994), pp. 185-209; B F. Haynes et al., AIDS Res. Hum Retroviruses 11, 211 (1995); G Fust et al., Immunol. Today 16 67 (1995); H Kohler et al., Immunologist 3, 32 (1995); D. C. Montefion et al., AIDS 5, 513 (1991), J. R Mascola et al., AIDS Res Hum. Retroviruses 9, 1175 (1993)
    • (1993) AIDS Res Hum. Retroviruses , vol.9 , pp. 1175
    • Mascola, J.R.1
  • 53
    • 0028825476 scopus 로고
    • S. L. Heath et al., Nature 377, 740 (1995).
    • (1995) Nature , vol.377 , pp. 740
    • Heath, S.L.1
  • 57
    • 0027526657 scopus 로고    scopus 로고
    • M. Clerici et al., J. Clin. Invest. 91, 759 (1993); M. Clerici et al., ibid. 93, 768 (1994); C. Graziosi et al , Science 265, 248 (1994); E. Maggi et al., ibid, p 244; V. S. Romagnani et al., AIDS Res. Hum. Retroviruses 10, iii (1994).
    • (1993) J. Clin. Invest. , vol.91 , pp. 759
    • Clerici, M.1
  • 58
    • 0028267888 scopus 로고
    • M. Clerici et al., J. Clin. Invest. 91, 759 (1993); M. Clerici et al., ibid. 93, 768 (1994); C. Graziosi et al , Science 265, 248 (1994); E. Maggi et al., ibid, p 244; V. S. Romagnani et al., AIDS Res. Hum. Retroviruses 10, iii (1994).
    • (1994) J. Clin. Invest. , vol.93 , pp. 768
    • Clerici, M.1
  • 59
    • 0028061081 scopus 로고
    • M. Clerici et al., J. Clin. Invest. 91, 759 (1993); M. Clerici et al., ibid. 93, 768 (1994); C. Graziosi et al , Science 265, 248 (1994); E. Maggi et al., ibid, p 244; V. S. Romagnani et al., AIDS Res. Hum. Retroviruses 10, iii (1994).
    • (1994) Science , vol.265 , pp. 248
    • Graziosi, C.1
  • 60
    • 0027526657 scopus 로고    scopus 로고
    • M. Clerici et al., J. Clin. Invest. 91, 759 (1993); M. Clerici et al., ibid. 93, 768 (1994); C. Graziosi et al , Science 265, 248 (1994); E. Maggi et al., ibid, p 244; V. S. Romagnani et al., AIDS Res. Hum. Retroviruses 10, iii (1994).
    • Science
    • Maggi, E.1
  • 61
    • 0028438380 scopus 로고
    • M. Clerici et al., J. Clin. Invest. 91, 759 (1993); M. Clerici et al., ibid. 93, 768 (1994); C. Graziosi et al , Science 265, 248 (1994); E. Maggi et al., ibid, p 244; V. S. Romagnani et al., AIDS Res. Hum. Retroviruses 10, iii (1994).
    • (1994) AIDS Res. Hum. Retroviruses , vol.10
    • Romagnani, V.S.1
  • 62
    • 0028861377 scopus 로고    scopus 로고
    • G. Pantaleo et al., N. Eng. J. Med. 332, 209 (1995), Y Cao et al , ibid., p. 201
    • (1995) N. Eng. J. Med. , vol.332 , pp. 209
    • Pantaleo, G.1
  • 63
    • 0028861377 scopus 로고    scopus 로고
    • G. Pantaleo et al., N. Eng. J. Med. 332, 209 (1995), Y Cao et al , ibid., p. 201
    • N. Eng. J. Med. , pp. 201
    • Cao, Y.1
  • 64
    • 0027217239 scopus 로고
    • B. Janvier et al , J AIDS 6, 898 (1993)
    • (1993) J AIDS , vol.6 , pp. 898
    • Janvier, B.1
  • 65
    • 0028321596 scopus 로고
    • S Pincus et al., J. Clin. Invest. 93, 2505 (1994); L A Cavacini et al., J. AIDS 6, 1093 (1993).
    • (1994) J. Clin. Invest. , vol.93 , pp. 2505
    • Pincus, S.1
  • 66
    • 0027508536 scopus 로고
    • S Pincus et al., J. Clin. Invest. 93, 2505 (1994); L A Cavacini et al., J. AIDS 6, 1093 (1993).
    • (1993) J. AIDS , vol.6 , pp. 1093
    • Cavacini, L.A.1
  • 67
    • 0025212678 scopus 로고
    • J. Homsy et al., J. Virol. 64, 1437 (1990).
    • (1990) J. Virol. , vol.64 , pp. 1437
    • Homsy, J.1
  • 68
    • 0022967777 scopus 로고    scopus 로고
    • C. M Walker, D J Moody, D. P. Stites, J A. Levy, Science 234, 1563 (1986); C. E. Mackewicz et al., J Clin. Invest 87, 1462 (1991); A L Landay et al., Clin. Immunol. Immunopathol. 69, 106 (1993); J. A. Levy et al , in (2), vol. 9, p 11, abstr. PS-05-2
    • (1986) Science , vol.234 , pp. 1563
    • Walker, C.M.1    Moody, D.J.2    Stites, D.P.3    Levy, J.A.4
  • 69
    • 0025891987 scopus 로고
    • C. M Walker, D J Moody, D. P. Stites, J A. Levy, Science 234, 1563 (1986); C. E. Mackewicz et al., J Clin. Invest 87, 1462 (1991); A L Landay et al., Clin. Immunol. Immunopathol. 69, 106 (1993); J. A. Levy et al , in (2), vol. 9, p 11, abstr. PS-05-2
    • (1991) J Clin. Invest , vol.87 , pp. 1462
    • Mackewicz, C.E.1
  • 70
    • 0027489609 scopus 로고
    • C. M Walker, D J Moody, D. P. Stites, J A. Levy, Science 234, 1563 (1986); C. E. Mackewicz et al., J Clin. Invest 87, 1462 (1991); A L Landay et al., Clin. Immunol. Immunopathol. 69, 106 (1993); J. A. Levy et al , in (2), vol. 9, p 11, abstr. PS-05-2
    • (1993) Clin. Immunol. Immunopathol. , vol.69 , pp. 106
    • Landay, A.L.1
  • 71
    • 0022967777 scopus 로고    scopus 로고
    • abstr. PS-05-2
    • C. M Walker, D J Moody, D. P. Stites, J A. Levy, Science 234, 1563 (1986); C. E. Mackewicz et al., J Clin. Invest 87, 1462 (1991); A L Landay et al., Clin. Immunol. Immunopathol. 69, 106 (1993); J. A. Levy et al , in (2), vol. 9, p 11, abstr. PS-05-2
    • 9th International Conference on AIDS , vol.9 , pp. 11
    • Levy, J.A.1
  • 72
    • 0028882466 scopus 로고
    • M Baier et al., Nature 378, 563 (1995)
    • (1995) Nature , vol.378 , pp. 563
    • Baier, M.1
  • 73
    • 0029417004 scopus 로고
    • F Cocchi et al., Science 270, 1811 (1995).
    • (1995) Science , vol.270 , pp. 1811
    • Cocchi, F.1
  • 74
  • 75
    • 0027304957 scopus 로고
    • J V Giorgi et al., J. AIDS 6, 904 (1993); H. N. Ho et al., J. Immunol. 150, 3070 (1993).
    • (1993) J. AIDS , vol.6 , pp. 904
    • Giorgi, J.V.1
  • 76
    • 0027263308 scopus 로고
    • J V Giorgi et al., J. AIDS 6, 904 (1993); H. N. Ho et al., J. Immunol. 150, 3070 (1993).
    • (1993) J. Immunol. , vol.150 , pp. 3070
    • Ho, H.N.1
  • 77
    • 0026635362 scopus 로고
    • A. Munoz et al , J AIDS 5, 694 (1992).
    • (1992) J AIDS , vol.5 , pp. 694
    • Munoz, A.1
  • 78
    • 0023896246 scopus 로고
    • M. Tersmette et al., J. Virol. 62, 2026 (1988); M. Tersmette et al., ibid 63, 2118 (1989); B. Asjo et al., AIDS Res Hum Retroviruses 6, 1177 (1990); C. Chang-Meyer et al., Proc. Natl. Acad. Sci U.S.A 85, 2815 (1988); P. Schellekens et al., AIDS 6, 665 (1992)
    • (1988) J. Virol. , vol.62 , pp. 2026
    • Tersmette, M.1
  • 79
    • 0024536114 scopus 로고
    • M. Tersmette et al., J. Virol. 62, 2026 (1988); M. Tersmette et al., ibid 63, 2118 (1989); B. Asjo et al., AIDS Res Hum Retroviruses 6, 1177 (1990); C. Chang-Meyer et al., Proc. Natl. Acad. Sci U.S.A 85, 2815 (1988); P. Schellekens et al., AIDS 6, 665 (1992)
    • (1989) J. Virol. , vol.63 , pp. 2118
    • Tersmette, M.1
  • 80
    • 0025018243 scopus 로고
    • M. Tersmette et al., J. Virol. 62, 2026 (1988); M. Tersmette et al., ibid 63, 2118 (1989); B. Asjo et al., AIDS Res Hum Retroviruses 6, 1177 (1990); C. Chang-Meyer et al., Proc. Natl. Acad. Sci U.S.A 85, 2815 (1988); P. Schellekens et al., AIDS 6, 665 (1992)
    • (1990) AIDS Res Hum Retroviruses , vol.6 , pp. 1177
    • Asjo, B.1
  • 81
    • 0023990347 scopus 로고
    • M. Tersmette et al., J. Virol. 62, 2026 (1988); M. Tersmette et al., ibid 63, 2118 (1989); B. Asjo et al., AIDS Res Hum Retroviruses 6, 1177 (1990); C. Chang-Meyer et al., Proc. Natl. Acad. Sci U.S.A 85, 2815 (1988); P. Schellekens et al., AIDS 6, 665 (1992)
    • (1988) Proc. Natl. Acad. Sci U.S.A , vol.85 , pp. 2815
    • Chang-Meyer, C.1
  • 82
    • 0026751270 scopus 로고
    • M. Tersmette et al., J. Virol. 62, 2026 (1988); M. Tersmette et al., ibid 63, 2118 (1989); B. Asjo et al., AIDS Res Hum Retroviruses 6, 1177 (1990); C. Chang-Meyer et al., Proc. Natl. Acad. Sci U.S.A 85, 2815 (1988); P. Schellekens et al., AIDS 6, 665 (1992)
    • (1992) AIDS , vol.6 , pp. 665
    • Schellekens, P.1
  • 83
    • 0027409934 scopus 로고
    • R. Conners et al., J. Virol 67, 1772 (1993); ibid 68, 4400 (1994); M. Koot et al , Ann Intern. Med 118, 681 (1993).
    • (1993) J. Virol , vol.67 , pp. 1772
    • Conners, R.1
  • 84
    • 0028228751 scopus 로고
    • R. Conners et al., J. Virol 67, 1772 (1993); ibid 68, 4400 (1994); M. Koot et al , Ann Intern. Med 118, 681 (1993).
    • (1994) J. Virol , vol.68 , pp. 4400
  • 85
    • 0027537480 scopus 로고
    • R. Conners et al., J. Virol 67, 1772 (1993); ibid 68, 4400 (1994); M. Koot et al , Ann Intern. Med 118, 681 (1993).
    • (1993) Ann Intern. Med , vol.118 , pp. 681
    • Koot, M.1
  • 86
    • 0027430660 scopus 로고
    • P. Gupta et al., Virology 196, 586 (1993); M deMartino et al , Lancet 343, 191 (1994); J Ferbas et al , J. Infect Dis. 172, 329 (1995), R. J. Trauger et al , Immunology 78, 611 (1993).
    • (1993) Virology , vol.196 , pp. 586
    • Gupta, P.1
  • 87
    • 0028054755 scopus 로고
    • P. Gupta et al., Virology 196, 586 (1993); M deMartino et al , Lancet 343, 191 (1994); J Ferbas et al , J. Infect Dis. 172, 329 (1995), R. J. Trauger et al , Immunology 78, 611 (1993).
    • (1994) Lancet , vol.343 , pp. 191
    • Demartino, M.1
  • 88
    • 0029084730 scopus 로고
    • P. Gupta et al., Virology 196, 586 (1993); M deMartino et al , Lancet 343, 191 (1994); J Ferbas et al , J. Infect Dis. 172, 329 (1995), R. J. Trauger et al , Immunology 78, 611 (1993).
    • (1995) J. Infect Dis. , vol.172 , pp. 329
    • Ferbas, J.1
  • 89
    • 0027410290 scopus 로고
    • P. Gupta et al., Virology 196, 586 (1993); M deMartino et al , Lancet 343, 191 (1994); J Ferbas et al , J. Infect Dis. 172, 329 (1995), R. J. Trauger et al , Immunology 78, 611 (1993).
    • (1993) Immunology , vol.78 , pp. 611
    • Trauger, R.J.1
  • 90
    • 0028177883 scopus 로고
    • T.H. Lee et al., J. AIDS 7,381 (1994); S Jurnaans et al., Virology 204, 223 (1994), J. W Mellors et al , Ann. Intern Med 122, 573 (1995).
    • (1994) J. AIDS , vol.7 , pp. 381
    • Lee, T.H.1
  • 91
    • 0028024718 scopus 로고
    • T.H. Lee et al., J. AIDS 7,381 (1994); S Jurnaans et al., Virology 204, 223 (1994), J. W Mellors et al , Ann. Intern Med 122, 573 (1995).
    • (1994) Virology , vol.204 , pp. 223
    • Jurnaans, S.1
  • 92
    • 0028909872 scopus 로고
    • T.H. Lee et al., J. AIDS 7,381 (1994); S Jurnaans et al., Virology 204, 223 (1994), J. W Mellors et al , Ann. Intern Med 122, 573 (1995).
    • (1995) Ann. Intern Med , vol.122 , pp. 573
    • Mellors, J.W.1
  • 93
    • 0027980442 scopus 로고
    • S. M. Wolinsky et al , personal communication It may be that syncytium-inducing T cell-tropic viruses are more easily cleared from the circulation than nonsyncytium-inducing (NSI) monocytotropic (MT) HIV, resulting in homogeneous NSI MT viruses being involved in transmission and being the predominant HIV strains present when the immune response can control HIV replication
    • E. L Delwart et al , J Virol 68, 6672 (1994), S. M. Wolinsky et al , personal communication It may be that syncytium-inducing T cell-tropic viruses are more easily cleared from the circulation than nonsyncytium-inducing (NSI) monocytotropic (MT) HIV, resulting in homogeneous NSI MT viruses being involved in transmission and being the predominant HIV strains present when the immune response can control HIV replication
    • (1994) J Virol , vol.68 , pp. 6672
    • Delwart, E.L.1
  • 95
    • 4243188985 scopus 로고    scopus 로고
    • in (2), abstr WS-BO3-3
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • Klein, M.1
  • 96
    • 0028950823 scopus 로고
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • (1995) J Exp Med. , vol.191 , pp. 1365
    • Klein, M.1
  • 97
    • 0025745271 scopus 로고
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • (1991) J. Infect. Dis. , vol.163 , pp. 959
    • Lifson, J.1
  • 98
    • 0028176469 scopus 로고
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • (1994) AIDS. Res Hum. Retroviruses , vol.10 , pp. 395
    • Greenough, T.C.1
  • 99
    • 4243175543 scopus 로고
    • A. C. Malwe et al., in (2), abstr SA-254
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • (1994) Clin. Res , vol.40
  • 100
    • 4243107006 scopus 로고    scopus 로고
    • abstr RO-A2204S4
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • Clin. Res
    • Harrer, E.1
  • 101
    • 4243084061 scopus 로고
    • M. Klein et al , in (2), abstr WS-BO3-3; M. Klein et al , J Exp Med. 191, 1365 (1995); J. Lifson et al., J. Infect. Dis. 163, 959 (1991); T. C. Greenough et al., AIDS. Res Hum. Retroviruses 10, 395 (1994); _, Clin. Res 40, 355A (1994), A. C. Malwe et al., in (2), abstr SA-254, E. Harrer et al., ibid., abstr RO-A2204S4; AIDS Res Hum. Retroviruses 10, S77 (1994).
    • (1994) AIDS Res Hum. Retroviruses , vol.10
  • 102
    • 0027416782 scopus 로고
    • J. A Levy, Pediatr. Res 33, S63 (1993); R. Conner and D. D. Ho, AIDS Res. Hum. Retroviruses 10, 321 (1994); S. Buchbinder et al., in Program and Abstracts of the 30th Interscience Conference on Antimicrobiological Agents and Chemotherapy, Atlanta, GA, 24 to 26 October 1990 (American Association of Microbiologists, Washington, DC, 1990), abstr. 304
    • (1993) Pediatr. Res , vol.33
    • Levy, J.A.1
  • 103
    • 0028415733 scopus 로고
    • J. A Levy, Pediatr. Res 33, S63 (1993); R. Conner and D. D. Ho, AIDS Res. Hum. Retroviruses 10, 321 (1994); S. Buchbinder et al., in Program and Abstracts of the 30th Interscience Conference on Antimicrobiological Agents and Chemotherapy, Atlanta, GA, 24 to 26 October 1990 (American Association of Microbiologists, Washington, DC, 1990), abstr. 304
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 321
    • Conner, R.1    Ho, D.D.2
  • 105
    • 0027420459 scopus 로고
    • J A Levy, AIDS 7, 1401 (1993).
    • (1993) AIDS , vol.7 , pp. 1401
    • Levy, J.A.1
  • 106
    • 0028236515 scopus 로고
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1994) J Infect. Dis , vol.169 , pp. 1236
    • Keet, M.1
  • 107
    • 0027265957 scopus 로고
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1993) Clin Exp. Immunol , vol.93 , pp. 331
    • Chargelegue, D.1    Otoole, C.M.2    Colvin, B.F.3
  • 108
    • 0026446532 scopus 로고
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1992) J. Infect Dis. , vol.166 , pp. 1217
    • Farzadegan, H.1
  • 109
    • 0028236515 scopus 로고
    • San Francisco, CA, 20 to 24 June abstr. SA287
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1990) 6th International Conference on AIDS , vol.6 , Issue.3 , pp. 153
    • Ascher, M.1
  • 110
    • 0025087191 scopus 로고
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1990) AIDS Res. Hum. Retroviruses , vol.6 , pp. 1183
    • Neurath, R.1
  • 111
    • 0027463698 scopus 로고
    • M Keet et al , J Infect. Dis 169, 1236 (1994), D Chargelegue, C. M. Otoole, B F Colvin, Clin Exp. Immunol 93, 331 (1993) ; H. Farzadegan et al., J. Infect Dis. 166, 1217 (1992), M. Ascher et al., 6th International Conference on AIDS, San Francisco, CA, 20 to 24 June 1990, vol. 6(3), p. 153, abstr. SA287, R Neurath, AIDS Res. Hum. Retroviruses 6, 1183 (1990); M Robert-Guroff et al , J. Infect Dis. 167, 538 (1993).
    • (1993) J. Infect Dis. , vol.167 , pp. 538
    • Robert-Guroff, M.1
  • 112
    • 4243086637 scopus 로고    scopus 로고
    • personal communication
    • H W Sheppard, personal communication.
    • Sheppard, H.W.1
  • 113
    • 0027409391 scopus 로고
    • L. Meyaard et al , Immunol. Today 14, 161 (1993), F. Miedma et al., Immunol. Rev. 140, 35 (1994); M. R. Helbert et al., Immunol Today 14, 340 (1993).
    • (1993) Immunol. Today , vol.14 , pp. 161
    • Meyaard, L.1
  • 114
    • 0028168943 scopus 로고
    • L. Meyaard et al , Immunol. Today 14, 161 (1993), F. Miedma et al., Immunol. Rev. 140, 35 (1994); M. R. Helbert et al., Immunol Today 14, 340 (1993).
    • (1994) Immunol. Rev. , vol.140 , pp. 35
    • Miedma, F.1
  • 115
    • 43949163241 scopus 로고
    • L. Meyaard et al , Immunol. Today 14, 161 (1993), F. Miedma et al., Immunol. Rev. 140, 35 (1994); M. R. Helbert et al., Immunol Today 14, 340 (1993).
    • (1993) Immunol Today , vol.14 , pp. 340
    • Helbert, M.R.1
  • 117
    • 0028269850 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1994) J. Clin. Invest , vol.93 , pp. 1293
    • Langlade-Demoyer, P.1
  • 118
    • 0027478866 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1993) Lancet , vol.341 , pp. 860
    • Rowland-Jones, S.1
  • 119
    • 0028946951 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1995) N. Eng. J Med. , vol.332 , pp. 833
    • Bryson, Y.J.1
  • 120
    • 0026534763 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1992) J. Infect. Dis. , vol.165 , pp. 1012
    • Clerici, M.1
  • 121
    • 0028269850 scopus 로고
    • Amsterdam, 19 to 24 July abstr POC4026
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1992) 8th International Conference on AIDS , vol.8 , Issue.2
    • Fowke, K.1
  • 122
    • 0028393523 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1994) Sci. Am. , vol.270 , pp. 20
    • Beardsley, T.1
  • 123
    • 0028269850 scopus 로고
    • paper presented Toronto, Ontario, 1 to 3 June
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1994) 4th Annual Canadian Conference on HIV-AIDS Research
    • Fowke, K.1
  • 124
    • 0028944192 scopus 로고
    • P Langlade-Demoyer et al , J. Clin. Invest 93, 1293 (1994), S, Rowland-Jones et al., Lancet 341, 860 (1993), Y. J Bryson et al., N. Eng. J Med. 332, 833 (1995), M Clerici et al., J. Infect. Dis. 165, 1012 (1992); K Fowke et al , 8th International Conference on AIDS, Amsterdam, 19 to 24 July 1992, vol. 8(2), p. c249, abstr POC4026, T. Beardsley, Sci. Am. 270, 20 (1994); K. Fowke et al., paper presented at the 4th Annual Canadian Conference on HIV-AIDS Research, Toronto, Ontario, 1 to 3 June 1994; S. Rowland-Jones et al., Nature Med. 1, 59 (1995).
    • (1995) Nature Med. , vol.1 , pp. 59
    • Rowland-Jones, S.1
  • 125
    • 4243154845 scopus 로고
    • paper presented at the National Academy of Science Institute of Medicine Roundtable on Development of Drugs and Vaccine For AIDS, Washington, DC, 10 December
    • J A. Levy, paper presented at the National Academy of Science Institute of Medicine Roundtable on Development of Drugs and Vaccine For AIDS, Washington, DC, 10 December 1993.
    • (1993)
    • Levy, J.A.1
  • 126
    • 0027547149 scopus 로고
    • in preparation
    • D. Pauza et al., J Med Primatol. 22, 154 (1993); in preparation; C J. Miller et al , J Virol. 68, 6391 (1994); R Benveniste et al., AIDS Res. Hum. Retroviruses 10, 585 (1994), M. Girard et al., 7th Colloque Des Cent Gardes, Pans, 26 to 28 October 1992 (Pasteur Vaccines, Paris, 1992), p. 75, 8th Colloque Des Cent Gardes, Paris, 25 to 27 October 1993 (Pasteur Vaccines, Paris, 1993), p 139.
    • (1993) J Med Primatol. , vol.22 , pp. 154
    • Pauza, D.1
  • 127
    • 0027936356 scopus 로고
    • D. Pauza et al., J Med Primatol. 22, 154 (1993); in preparation; C J. Miller et al , J Virol. 68, 6391 (1994); R Benveniste et al., AIDS Res. Hum. Retroviruses 10, 585 (1994), M. Girard et al., 7th Colloque Des Cent Gardes, Pans, 26 to 28 October 1992 (Pasteur Vaccines, Paris, 1992), p. 75, 8th Colloque Des Cent Gardes, Paris, 25 to 27 October 1993 (Pasteur Vaccines, Paris, 1993), p 139.
    • (1994) J Virol. , vol.68 , pp. 6391
    • Miller, C.J.1
  • 128
    • 0027547149 scopus 로고
    • D. Pauza et al., J Med Primatol. 22, 154 (1993); in preparation; C J. Miller et al , J Virol. 68, 6391 (1994); R Benveniste et al., AIDS Res. Hum. Retroviruses 10, 585 (1994), M. Girard et al., 7th Colloque Des Cent Gardes, Pans, 26 to 28 October 1992 (Pasteur Vaccines, Paris, 1992), p. 75, 8th Colloque Des Cent Gardes, Paris, 25 to 27 October 1993 (Pasteur Vaccines, Paris, 1993), p 139.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 585
    • Benveniste, R.1
  • 129
    • 0027547149 scopus 로고
    • Pans, 26 to 28 October 1992 Pasteur Vaccines, Paris
    • D. Pauza et al., J Med Primatol. 22, 154 (1993); in preparation; C J. Miller et al , J Virol. 68, 6391 (1994); R Benveniste et al., AIDS Res. Hum. Retroviruses 10, 585 (1994), M. Girard et al., 7th Colloque Des Cent Gardes, Pans, 26 to 28 October 1992 (Pasteur Vaccines, Paris, 1992), p. 75, 8th Colloque Des Cent Gardes, Paris, 25 to 27 October 1993 (Pasteur Vaccines, Paris, 1993), p 139.
    • (1992) 7th Colloque des Cent Gardes , pp. 75
    • Girard, M.1
  • 130
    • 0027547149 scopus 로고
    • Paris, 25 to 27 October 1993 Pasteur Vaccines, Paris
    • D. Pauza et al., J Med Primatol. 22, 154 (1993); in preparation; C J. Miller et al , J Virol. 68, 6391 (1994); R Benveniste et al., AIDS Res. Hum. Retroviruses 10, 585 (1994), M. Girard et al., 7th Colloque Des Cent Gardes, Pans, 26 to 28 October 1992 (Pasteur Vaccines, Paris, 1992), p. 75, 8th Colloque Des Cent Gardes, Paris, 25 to 27 October 1993 (Pasteur Vaccines, Paris, 1993), p 139.
    • (1993) 8th Colloque des Cent Gardes , pp. 139
  • 132
    • 4243159461 scopus 로고    scopus 로고
    • personal communication
    • N Letvin, personal communication.
    • Letvin, N.1
  • 133
    • 0028324237 scopus 로고
    • M. Makino et al., J. Immunol 152, 4157 (1994).
    • (1994) J. Immunol , vol.152 , pp. 4157
    • Makino, M.1
  • 135
    • 0028286021 scopus 로고
    • A Saah. in (40)
    • R. Kaslow, paper presented at the National Institute of Allergy and Infectious Diseases Workshop on HIV-SIV Pathogenesis and Mucosal Transmission, Washington, DC, 14 to 17 March 1994; R. Kaslow and D. Mann, J. Infect Dis. 169, 1332 (1994); A Saah. in (40), D. L. Mann et al., AIDS Res. Hum Retroviruses 8, 1345 (1992).
    • (1994) J. Infect Dis. , vol.169 , pp. 1332
    • Kaslow, R.1    Mann, D.2
  • 136
    • 0026697821 scopus 로고
    • R. Kaslow, paper presented at the National Institute of Allergy and Infectious Diseases Workshop on HIV-SIV Pathogenesis and Mucosal Transmission, Washington, DC, 14 to 17 March 1994; R. Kaslow and D. Mann, J. Infect Dis. 169, 1332 (1994); A Saah. in (40), D. L. Mann et al., AIDS Res. Hum Retroviruses 8, 1345 (1992).
    • (1992) AIDS Res. Hum Retroviruses , vol.8 , pp. 1345
    • Mann, D.L.1
  • 137
    • 4243100301 scopus 로고    scopus 로고
    • in (2), p 23, abstr. WS-A07-3
    • F. A. Plummer et al., in (2), p 23, abstr. WS-A07-3,
    • Plummer, F.A.1
  • 138
    • 0025902165 scopus 로고
    • E. J Stott et al., Nature 353, 393 (1991);
    • (1991) Nature , vol.353 , pp. 393
    • Stott, E.J.1
  • 140
    • 0027049212 scopus 로고
    • L. O Arthur et al., Science 258, 1935 (1992).
    • (1992) Science , vol.258 , pp. 1935
    • Arthur, L.O.1
  • 142
    • 0025895511 scopus 로고
    • L. G Louie, B Newman, M King, J AIDS 4, 814 (1991), A G Wilson et al , J. Exp Med. 177, 557 (1993), M. Klein et al., J. Infect Dis. 159, 1244 (1994); P. U. Cameron et al., Hum. Immunol 29, 282 (1990).
    • (1991) J AIDS , vol.4 , pp. 814
    • Louie, L.G.1    Newman, B.2    King, M.3
  • 143
    • 0027534914 scopus 로고
    • L. G Louie, B Newman, M King, J AIDS 4, 814 (1991), A G Wilson et al , J. Exp Med. 177, 557 (1993), M. Klein et al., J. Infect Dis. 159, 1244 (1994); P. U. Cameron et al., Hum. Immunol 29, 282 (1990).
    • (1993) J. Exp Med. , vol.177 , pp. 557
    • Wilson, A.G.1
  • 144
    • 0028357723 scopus 로고
    • L. G Louie, B Newman, M King, J AIDS 4, 814 (1991), A G Wilson et al , J. Exp Med. 177, 557 (1993), M. Klein et al., J. Infect Dis. 159, 1244 (1994); P. U. Cameron et al., Hum. Immunol 29, 282 (1990).
    • (1994) J. Infect Dis. , vol.159 , pp. 1244
    • Klein, M.1
  • 145
    • 0025605233 scopus 로고
    • L. G Louie, B Newman, M King, J AIDS 4, 814 (1991), A G Wilson et al , J. Exp Med. 177, 557 (1993), M. Klein et al., J. Infect Dis. 159, 1244 (1994); P. U. Cameron et al., Hum. Immunol 29, 282 (1990).
    • (1990) Hum. Immunol , vol.29 , pp. 282
    • Cameron, P.U.1
  • 147
    • 4243079485 scopus 로고    scopus 로고
    • in (8), abstr. 163A
    • R. Detels et al., in (8), abstr. 163A.
    • Detels, R.1
  • 149
    • 0026027945 scopus 로고
    • M. D. Daniel, F. Kirchhoff, S. C. Czajak, P K Sehgal. R. C. Desrosier, Science 258, 1938 (1992); A. M. Hardy et al , J AIDS 4, 386 (1991)
    • (1991) J AIDS , vol.4 , pp. 386
    • Hardy, A.M.1
  • 150
    • 0029071719 scopus 로고
    • T. Travers et al., Science 268, 1612 (1995).
    • (1995) Science , vol.268 , pp. 1612
    • Travers, T.1
  • 151
    • 0028944667 scopus 로고
    • T W. Baba et al , ibid. 267, 1820 (1995).
    • (1995) Science , vol.267 , pp. 1820
    • Baba, T.W.1
  • 152
    • 4243139148 scopus 로고    scopus 로고
    • note
    • + patients with a HIV envelope peptide containing a CTL epitope restricted by HLA-B7 The peptide immunogen is formulated in an adjuvant, ISA-51, that has been shown to induce MHC class I CTLs peptide immunogens in mice and rhesus monkeys.
  • 153
    • 0026552401 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1992) AIDS , vol.6 , pp. 453
    • Pang, S.1
  • 154
    • 0026695382 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1992) Virology , vol.189 , pp. 103
    • Wolfs, T.F.W.1
  • 155
    • 0026686475 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1992) Proc. Natl Acad. Sci. USA , vol.89 , pp. 7365
    • Cichutek, K.1
  • 156
    • 4243107005 scopus 로고    scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • Proc. Natl Acad. Sci. USA , pp. 10247
    • McNeaney, T.1
  • 157
    • 0027229245 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1993) J. Virol. , vol.67 , pp. 3345
    • Zhang, L.Q.1
  • 158
    • 0026551082 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1992) Science , vol.255 , pp. 1134
    • Wolinsky, S.M.1
  • 159
    • 0027422278 scopus 로고
    • S Pang et al , AIDS 6, 453 (1992), T F. W Wolfs et al , Virology 189, 103 (1992), K. Cichutek et al., Proc. Natl Acad. Sci. USA 89, 7365 (1992); T. McNeaney et al., ibid., p. 10247; L Q Zhang et al., J. Virol. 67, 3345 (1993), S M. Wolinsky et al., Science 255, 1134 (1992); T. Zhu et al., ibid. 261, 1179 (1993).
    • (1993) Science , vol.261 , pp. 1179
    • Zhu, T.1
  • 160
    • 0025916851 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1991) AIDS Res. Hum. Retroviruses , vol.7 , pp. 361
    • Schnittman, S.1
  • 161
    • 0026785594 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1992) Curr. Opin. Immunol. , vol.4 , pp. 475
    • Pomerantz, R.J.1
  • 162
    • 0026439078 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1992) Proc. Natl. Acad. Sci. U.S.A , vol.89 , pp. 10663
    • Seshamma, T.1
  • 163
    • 0027787919 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 1257
    • Arens, M.1
  • 164
    • 0028819068 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1995) J. Virol. , vol.69 , pp. 1868
    • Michael, N.L.1
  • 165
    • 0028158879 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1994) Proc. Natl Acad. Sci. U.S.A. , vol.91 , pp. 1104
    • Saksela, K.1
  • 166
    • 0028915064 scopus 로고
    • S. Schnittman et al , AIDS Res. Hum. Retroviruses 7, 361 (1991): R. J. Pomerantz et al., Curr. Opin. Immunol. 4, 475 (1992); T Seshamma et al., Proc. Natl. Acad. Sci. U.S.A 89, 10663 (1992); M Arens et al , AIDS Res. Hum. Retroviruses 9, 1257 (1993); N L. Michael et al., J. Virol. 69, 1868 (1995), K. Saksela et al., Proc. Natl Acad. Sci. U.S.A. 91, 1104 (1994); M R. Furtado, L A. Kingsley, S. M. Wolinsky, J. Virol. 69, 2092 (1995)
    • (1995) J. Virol. , vol.69 , pp. 2092
    • Furtado, M.R.1    Kingsley, L.A.2    Wolinsky, S.M.3
  • 168
    • 0026667917 scopus 로고
    • J. Learmont et al., Lancet 340, 863 (1992); F. Kirchhoff et al , N. Eng J Med. 332, 228 (1995); N J Deacon et al , Science 270, 988 (1995)
    • (1992) Lancet , vol.340 , pp. 863
    • Learmont, J.1
  • 169
    • 0028835788 scopus 로고
    • J. Learmont et al., Lancet 340, 863 (1992); F. Kirchhoff et al , N. Eng J Med. 332, 228 (1995); N J Deacon et al , Science 270, 988 (1995)
    • (1995) N. Eng J Med. , vol.332 , pp. 228
    • Kirchhoff, F.1
  • 170
    • 0028804160 scopus 로고
    • J. Learmont et al., Lancet 340, 863 (1992); F. Kirchhoff et al , N. Eng J Med. 332, 228 (1995); N J Deacon et al , Science 270, 988 (1995)
    • (1995) Science , vol.270 , pp. 988
    • Deacon, N.J.1
  • 171
    • 0025002594 scopus 로고
    • D. L. Mann et al., J AIDS 3 (suppl ), S51 (1990).
    • (1990) J AIDS , vol.3 , Issue.SUPPL.
    • Mann, D.L.1
  • 172
    • 0024273321 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1988) J AIDS , vol.1 , pp. 13
    • Mann, D.L.1
  • 173
    • 0021603052 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1984) Hum. Immunol. , vol.11 , pp. 99
    • Pollack, M.S.1
  • 174
    • 0021067977 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1983) Dis. Markers , vol.1 , pp. 135
    • Pollack, M.S.1    Safai, B.2    DuPont, B.3
  • 175
    • 84921012830 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1986) Lancet , vol.2 , pp. 1187
    • Scorza-Smeraldi, R.1
  • 176
    • 0021266679 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1984) Tissue Antigens , vol.23 , pp. 240
    • Gontu, L.1
  • 177
    • 0021740660 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1984) Tissue Antigens , vol.24 , pp. 313
    • Papasteriades, C.1
  • 178
    • 0021214442 scopus 로고
    • D. L Mann et al , ibid. 1, 13 (1988); M. S. Pollack et al., Hum. Immunol. 11, 99 (1984), M. S. Pollack, B. Safai, B. DuPont. Dis. Markers 1. 135 (1983), R. Scorza-Smeraldi et al., Lancet ii, 1187 (1986), L Gontu et al , Tissue Antigens 23, 240 (1984), C Papasteriades et al., ibid. 24, 313 (1984) ; H. E Prince et al., J. Clin Immunol 4, 242 (1984).
    • (1984) J. Clin Immunol , vol.4 , pp. 242
    • Prince, H.E.1
  • 179
    • 0025212704 scopus 로고
    • R Kaslow et al., Lancet 335, 927 (1990); C. M. Steel et al., ibid. i, 1186 (1988); C. Kaplan et al., Hum. Hered. 40, 290 (1990); an excellent recent critical review of the association Of DQZ-DR3-B8-Cw7-Al as well as other HLA alleles with clinical manifestations of HIV infection is: J. J. Just, Hum. Immunol. 44, 156 (1995).
    • (1990) Lancet , vol.335 , pp. 927
    • Kaslow, R.1
  • 180
    • 0025212704 scopus 로고
    • R Kaslow et al., Lancet 335, 927 (1990); C. M. Steel et al., ibid. i, 1186 (1988); C. Kaplan et al., Hum. Hered. 40, 290 (1990); an excellent recent critical review of the association Of DQZ-DR3-B8-Cw7-Al as well as other HLA alleles with clinical manifestations of HIV infection is: J. J. Just, Hum. Immunol. 44, 156 (1995).
    • (1988) Lancet , vol.1 , pp. 1186
    • Steel, C.M.1
  • 181
    • 0025176026 scopus 로고
    • R Kaslow et al., Lancet 335, 927 (1990); C. M. Steel et al., ibid. i, 1186 (1988); C. Kaplan et al., Hum. Hered. 40, 290 (1990); an excellent recent critical review of the association Of DQZ-DR3-B8-Cw7-Al as well as other HLA alleles with clinical manifestations of HIV infection is: J. J. Just, Hum. Immunol. 44, 156 (1995).
    • (1990) Hum. Hered. , vol.40 , pp. 290
    • Kaplan, C.1
  • 182
    • 0029618381 scopus 로고
    • R Kaslow et al., Lancet 335, 927 (1990); C. M. Steel et al., ibid. i, 1186 (1988); C. Kaplan et al., Hum. Hered. 40, 290 (1990); an excellent recent critical review of the association Of DQZ-DR3-B8-Cw7-Al as well as other HLA alleles with clinical manifestations of HIV infection is: J. J. Just, Hum. Immunol. 44, 156 (1995).
    • (1995) Hum. Immunol. , vol.44 , pp. 156
    • Just, J.J.1
  • 183
    • 4243175544 scopus 로고    scopus 로고
    • in (2), abstr. WS-A07-6
    • D. Mann et al., in (2), abstr. WS-A07-6.
    • Mann, D.1
  • 185
    • 0023718365 scopus 로고
    • R. Scorza-Smeraldi et al , Hum Immunol 22, 73 (1988); S. Itescu et al., J. AIDS 5, 37 (1991). P. De Paoli et al., Tissue Antigens 27, 116 (1986), C Raffoux et al., ibid. 29, 60 (1987) ; J. M. Cruse et al., Pathobiology 59, 324 (1991)
    • (1988) Hum Immunol , vol.22 , pp. 73
    • Scorza-Smeraldi, R.1
  • 186
    • 0023718365 scopus 로고
    • R. Scorza-Smeraldi et al , Hum Immunol 22, 73 (1988); S. Itescu et al., J. AIDS 5, 37 (1991). P. De Paoli et al., Tissue Antigens 27, 116 (1986), C Raffoux et al., ibid. 29, 60 (1987) ; J. M. Cruse et al., Pathobiology 59, 324 (1991)
    • (1991) J. AIDS , vol.5 , pp. 37
    • Itescu, S.1
  • 187
    • 0022618350 scopus 로고
    • R. Scorza-Smeraldi et al , Hum Immunol 22, 73 (1988); S. Itescu et al., J. AIDS 5, 37 (1991). P. De Paoli et al., Tissue Antigens 27, 116 (1986), C Raffoux et al., ibid. 29, 60 (1987) ; J. M. Cruse et al., Pathobiology 59, 324 (1991)
    • (1986) Tissue Antigens , vol.27 , pp. 116
    • De Paoli, P.1
  • 188
    • 0023121038 scopus 로고
    • R. Scorza-Smeraldi et al , Hum Immunol 22, 73 (1988); S. Itescu et al., J. AIDS 5, 37 (1991). P. De Paoli et al., Tissue Antigens 27, 116 (1986), C Raffoux et al., ibid. 29, 60 (1987) ; J. M. Cruse et al., Pathobiology 59, 324 (1991)
    • (1987) Tissue Antigens , vol.29 , pp. 60
    • Raffoux, C.1
  • 189
    • 0025898710 scopus 로고
    • R. Scorza-Smeraldi et al , Hum Immunol 22, 73 (1988); S. Itescu et al., J. AIDS 5, 37 (1991). P. De Paoli et al., Tissue Antigens 27, 116 (1986), C Raffoux et al., ibid. 29, 60 (1987) ; J. M. Cruse et al., Pathobiology 59, 324 (1991)
    • (1991) Pathobiology , vol.59 , pp. 324
    • Cruse, J.M.1
  • 191
    • 0028139233 scopus 로고
    • S. Itescu and R. Winchester, Rheum. Dis. Clin N. Am. 18, 683 (1992); S. Itescu et al., Proc. Natl. Acad. Sci U.S.A. 91, 11472 (1994).
    • (1994) Proc. Natl. Acad. Sci U.S.A. , vol.91 , pp. 11472
    • Itescu, S.1
  • 192
    • 4243116070 scopus 로고    scopus 로고
    • in (2), p. 41, abstr. WS-B03-2; in (43)
    • S. Buchbinder et al., in (2), p. 41, abstr. WS-B03-2; in (43).
    • Buchbinder, S.1
  • 193
    • 0028227604 scopus 로고
    • L. Duan et al., J. Virol. 68, 4302 (1994).
    • (1994) J. Virol. , vol.68 , pp. 4302
    • Duan, L.1
  • 195
    • 4243052397 scopus 로고    scopus 로고
    • note
    • We thank H. Sheppard, H Saah, R. Kaslow, D. Pauza, C. Miller, N. Letvin, J. Sullivan, S. Buchbinder, K Luzuriaga, D. Mann, L Arthur, K. Fowke, P. Fultz, G. Shearer, J Giorgi, R. Winchester, S. Wolinsky, H. Golding, J. Levy, S. Koenig, and J. Mullins for discussions and use of unpublished data, L. Holloman for library assistance, and K. McClammy for secretarial assistance. Supported by NIH grants CA-28936, Al-28662, CA-43447, and AI-35351. B.F.H. is a Carter-Wallace Fellow for AIDS Research.


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