Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1

Journal of Biological Chemistry

Volumn 272, Issue 13, 1997, Pages 8340-8345

  Ambrosini, Grazia ^a   Plescia, Janet ^a   Chu, Kirk C ^b   High, Katherine A ^b   Altieri, Dario C ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL RECEPTOR; EPIDERMAL GROWTH FACTOR; PROTEINASE;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME BINDING; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SEQUENCE ANALYSIS; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

BINDING SITES; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; FACTOR XA; HUMANS; LEUCINE; PROTHROMBIN; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030934186     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.13.8340     Document Type: Article

References (41)

1. Davie, E. W., Fujikawa, K., and Kisiel, W. (1991) Biochemistry 30, 10363-10370
2. Fukudome, K., and Esmon, C. T. (1994) J. Biol. Chem. 269, 26486-26491
3. Roldan, A. L., Cubellis, M. V., Masucci, M. T., Behrendt, N., Lund, L. R., Danø, K., Appella, E., and Blasi, F. (1990) EMBO J. 9, 467-474
4. Vu, T.-K. H., Hung, D. T., Wheaton, V. I., and Coughlin, S. R. (1991) Cell 64, 1057-1068
5. Edgington, T. S., Mackman, N., Brand, K., and Ruf, W. (1991) Thromb. Haemost. 66, 67-79
6. Gordon, E. M., Venkatesan, N., Salazar, R., Tang, H., K., S.-S., Buckley, S., Warburton, D., and Hall, F. L. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2174-2179
7. Cheung, W.-F., van den Born, J., Kuhn, K., Kjellen, L., Hudson, B. G., and Stafford, D. W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11068-11073
8. Altieri, D. C., and Edgington, T. S. (1988) J. Biol. Chem. 263, 7007-7015
9. Altieri, D. C. (1995) FASEB J. 9, 860-865
10. Mirza, H., Yatsula, V., and Bahou, W. F. (1996) J. Clin. Invest. 97, 1705-1714
11. Molloy, C. J., Pawlowski, J. E., Taylor, D. S., Turner, C. E., Weber, H., Peluso, M., and Seiler, S. M. (1996) J. Clin. Invest. 97, 1173-1183
12. Daniel, T. O., Gibbs, V. C., Milfay, D. F., Garovoy, M. R., and Williams, L. T. (1986) J. Biol. Chem. 261, 9579-9582
13. Grandaliano, G., Valente, A. J., and Abboud, H. E. (1994) J. Exp. Med. 179, 1737-1741
14. Clohisy, D. R., Erdmann, J. M., and Wilner, G. D. (1990) J. Biol. Chem. 265, 7729-7732
15. Gajdusek, C., Carbon, S., Ross, R., Nawroth, P., and Stern, D. (1986) J. Cell Biol. 103, 419-428
16. Gasic, G. P., Arenas, C. P., Gasic, T. B., and Gasic, G. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 2317-2320
17. Altieri, D. C. (1995) J. Leukocyte Biol. 58, 120-127
18. Grey, S. T., and Hancock, W. W. (1996) J. Immunol. 156, 2256-2263
19. Nicholson, A. C., Nachman, R. L., Altieri, D. C., Summers, B. D., Ruf, W., Edgington, T. S., and Hajjar, D. P. (1996) J. Biol. Chem. 271, 28407-28413
20. Bouchard, B. A., Altieri, D. C., Adida-Sirugo, C., and Tracy, P. B. (1995) Blood 86, 1788
21. Eisenberg, P. R., Siegel, J. E., Abendschein, D. R., and Miletich, J. P. (1993) J. Clin. Invest. 91, 1877-1883
22. Ross, R. (1993) Nature 362, 801-809
23. Vlasuk, G. P. (1993) Thromb. Haemost. 70, 212-216
24. Altieri, D. C., Etingin, O. R., Fair, D. S., Brunck, T. K., Geltosky, J. E., Hajjar, D. P., and Edgington, T. (1991) Science 254, 1200-1202
25. Fung, M. R., Hay, C. W., and MacGillivray, R. T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 3591-3595
26. Fraker, P. J., and Speck, J. C., Jr. (1978) Biochem. Biophys. Res. Commun. 80, 849-857
27. Horton, R. M., Hunt, H. D., Ho, S. N., Pullen, J. K., and Pease, L. R. (1989) Gene (Amst.) 77, 61-69
28. Anderson, S., Davis, D. L., Dahlback, H., Jornvall, H., and Russell, D. W. (1989) J. Biol. Chem. 264, 8222-8229
29. Ambrosini, G., and Altieri, D. C. (1996) J. Biol. Chem. 271, 1243-1248
30. Walter, J., You, Q., Hagstrom, J. N., Sands, M., and High, K. A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 3056-3061
31. Smith, K. J., and Ono, K. (1984) Thromb. Res. 33, 211-224
32. Price, P. A. (1983) Methods Enzymol. 91, 13-17
33. Nystedt, S., Emilsson, K., Wahlestedt, C., and Sundelin, J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 9208-9212
34. Rimon, S., Melamed, R., Savion, N., Scott, T., Nawroth, P. P., and Stern, D. M. (1987) J. Biol. Chem. 262, 6023-6031
35. Appella, E., Robinson, E. A., Ullrich, S. J., Stoppelli, M. P., Corti, A., Cassani, G., and Blasi, F. (1987) J. Biol. Chem. 262, 4437-4440
36. Padmanabhan, K. P., Padmanabhan, A., and Tulinsky, A. (1993) J. Mol. Biol. 232, 947-966
37. Brandstetter, H., Bauer, M., R., H., Lollar, P., and Bode, W. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 9796-9800
38. Keyt, B., Furie, B. C., and Furie, B. (1982) J. Biol. Chem. 257, 8687-8695
39. Persson, E., Valcarce, C., and Stenflo, J. (1991) J. Biol. Chem. 266, 2453-2458
40. Astermark, J., Hogg, P. J., and Stenflo, J. (1994) J. Biol. Chem. 269, 3682-3689
41. Persson, E., Hogg, P. J., and Stenflo, J. (1993) J. Biol. Chem. 268, 22531-22539