Structure-based understanding of ligand affinity using human thrombin as a model system

Biochemistry

Volumn 35, Issue 30, 1996, Pages 9690-9699

  Nienaber, Vicki L ^a,b   Mersinger, Lawrence J ^a   Kettner, Charles A ^a  

^a DUPONT COMPANY   (United States)

^b ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THROMBIN; THROMBIN INHIBITOR; TRIPEPTIDE DERIVATIVE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; HUMAN; HUMAN CELL; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ELECTROCHEMISTRY; HUMANS; HYDROGEN BONDING; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGOPEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBIN;

EID: 0029786114     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952164b     Document Type: Article

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