Origin of starter units for erythromycin biosynthesis

Biochemistry

Volumn 37, Issue 31, 1998, Pages 11012-11017

  Weissman, Kira J ^a   Bycroft, Matthew ^a   Staunton, James ^a   Leadlay, Peter F ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROMYCIN; POLYKETIDE; SYNTHETASE;

ANTIBIOTIC BIOSYNTHESIS; ARTICLE; CATALYSIS; DECARBOXYLATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBSTRATE; NONHUMAN; PRIORITY JOURNAL;

ACYL COENZYME A; CARBOXY-LYASES; DEUTERIUM OXIDE; ERYTHROMYCIN; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LACTONES; MAGNETIC RESONANCE SPECTROSCOPY; MULTIENZYME COMPLEXES; SACCHAROPOLYSPORA; THIOLESTER HYDROLASES;

ILEX COOKII;

EID: 0032483126     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9806246     Document Type: Article

References (35)

1. O'Hagan, D. (1995) The Polyketide Metabolites, Ellis Horwood, Chichester, U.K.
2. Hopwood, D. A., and Sherman, D. H. (1990) Annu. Rev. Genet. 24, 37-66.
3. Hutchinson, C. R., and Fujii, I. (1995) Annu. Rev. Microbiol. 49, 201-238.
4. Leadlay, P. F. (1997) Curr. Opin. Chem. Biol. 1, 162-168.
5. Khosla, C., and Zawada, R. J. X. (1994) Trends Biotechnol. 14, 335-341.
6. Cortés, J., Haydock, S. F., Roberts, G. A., Bevitt, D. J., and Leadlay, P. F. (1990) Nature 348, 176-178.
7. Donadio, S., Staver, M. J., McAlpine, J. B., Swanson, S. L., and Katz, L. (1991) Science 252, 675-679.
8. MacNeil, D. J., Occi, J. L., Gewain, K. M., MacNeil, T., Gibbons, P. H., Ruby, C. L., and Danis, S. J. (1992) Gene 115, 119-125.
9. Swan, D., Rodriguez, A. M., Vilches, C., Méndez, C., and Salas, J. A. (1994) Mol. Gen. Genet. 242, 358-362.
10. Hu, Z. H., Bao, K., Zhou, X. F., Zhou, Q., Hopwood, D. A., Kieser, T., and Deng, Z. X. (1994) Mol. Microbiol. 14, 163-172.
11. Marsden, A. F. A., Caffrey, P., Aparicio, J. F., Loughran, M. S., Staunton, J., and Leadlay, P. F. (1994) Science 263, 378-380.
12. Caffrey, P., Bevitt, D. J., Staunton, J., and Leadlay, P. F. (1992) FEES Lett. 304, 225-228.
13. Wiesmann, K. E. H., Cortés, J., Brown, M. J. B., Cutter, A. L., Staunton, J., and Leadlay, P. F. (1995) Chem. Biol. 2, 583-589.
14. Dutton, C. J., Gibson, S. P., Goudie, A. C., Holdom, K. S., Pacey, M. S., Ruddock, J. C., Bulock, J. D., and Richards, M. K. (1991) J. Antibiot. 44, 357-365.
15. Traeder, W. (1994) Tieraerztl. Umsch. 49, 465-469.
16. Pereda, A., Summers, R., Stassi, D., and Katz, L. (1998) Microbiology 144, 543-553.
17. Marsden, A. F. A., Wilkinson, B., Cortes, J., Dunster, N. J., Staunton, J., and Leadlay, P. F. (1998) Science 279, 199-202.
18. Kuhstoss, S., Huber, M., Turner, J. R., Paschal, J. W., and Rao, R. N. (1996) Gene 183, 231-236.
19. Pieper, R., Luo, G., Cane, D. E., and Khosla, C. (1995) J. Am. Chem. Soc. 117, 11373-11374.
20. Weissman, K. J., Timoney, M., Bycroft, M., Grice, P., Hanefeld, U., Staunton, J., and Leadlay, P. F. (1997) Biochemistry 36, 13849-13855.
21. Chuck, J., McPherson, M., Huang, H., Jacobsen, J. R., Khosla, C., and Cane, D. E. (1997) Chem. Biol. 4, 757-766.
22. Dutton, C. J., Hooper, A. M., Leadlay, P. F., and Staunton, J. (1994) Tetrahedron Lett. 35, 327-330.
23. Jacobsen, J. R., Hutchinson, C. R., Cane, D. E., and Khosla, C. (1997) Science 277, 367-369.
24. Ikeda, H., and Omura, S. (1997) Chem. Rev. 97, 2591-2609.
25. Hafner, E. W., Holley, B. W., Holdom, K. S., Lee, S. E., Wax, R. G., Beck, D., McArthur, H. A. I., and Wernau, W. C. (1991) J. Antibiot. 44, 349-356.
26. Pieper, R., Ebert-Khosla, S., Cane, D., and Khosla, C. (1996) Biochemistry 35, 2054-2060.
27. Pieper, R., Gokhale, R. S., Luo, G., Cane, D. E., and Khosla, C. (1997) Biochemistry 36, 1846-1851.
28. Kao, C. M., Luo, G., Katz, L., Cane, D. E., and Khosla, C. (1995) J. Am. Chem. Soc. 117, 9105-9106.
29. Kresze, G. B., Stever, L., Oesterhelt, D., and Lynen, F. (1977) Eur. J. Biochem. 79, 191-199.
30. Donadio, S., and Katz, L. (1992) Gene 111, 51-60.
31. Staunton, J. (1991) Angew. Chem., Int. Ed. Engl. 30, 1302-1306.
32. Cortes, J., Wiesmann, K. E. H., Roberts, G. A., Brown, M. J. B., Staunton, J., and Leadlay, P. F. (1995) Science 268, 1487-1489.
33. Roberts, G. A., Staunton, J., and Leadlay, P. F. (1993) Eur. J. Biochem. 214, 305-311.
34. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254.
35. Hsieh, Y.-J., and Kolattukudy, P. E. (1994) J. Bacteriol. 176, 714-724.