The Drosophila protein Dof is specifically required for FGF signaling

Molecular Cell

Volumn 2, Issue 4, 1998, Pages 515-525

  Vincent, Stéphane ^a   Wilson, Robert ^b   Coelho, Carmen ^b,c   Affolter, Markus ^a   Leptin, Maria ^b  

^a UNIVERSITY OF BASEL   (Switzerland)

^b UNIVERSITY OF COLOGNE   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DROSOPHILA PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR; INSECT PROTEIN; PROTEIN KINASE (CALCIUM,CALMODULIN); STUMPS PROTEIN, DROSOPHILA;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; CELL MOTION; CHEMISTRY; CYTOLOGY; CYTOPLASM; DROSOPHILA; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC EPISTASIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; MESODERM; METABOLISM; MOLECULAR GENETICS; MORPHOGENESIS; MUTATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRACHEA;

AMINO ACID SEQUENCE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL MOVEMENT; CYTOPLASM; DNA, COMPLEMENTARY; DROSOPHILA; DROSOPHILA PROTEINS; EPISTASIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSECT PROTEINS; MESODERM; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTATION; RECEPTORS, FIBROBLAST GROWTH FACTOR; SIGNAL TRANSDUCTION; TRACHEA;

EID: 0032185773     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80151-3     Document Type: Article

References (47)

1. Batchelor, A.H., Piper, D.E., de la Brousse, F.C., McKnight, S.L., and Wolberger, C. (1998). The structure of GABP α/β: an ETS domain-ankyrin repeat heterodimer bound to DNA. Science 279, 1037-1041.
2. Beiman, M., Shilo, B.Z., and Volk, T. (1996). Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. Genes Dev. 10, 2993-3002.
3. Brown, N.H., and Kafatos, F.C. (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203, 425-437.
4. Burke, D., Wilkes, D., Blundell, T.L., and Malcolm, S. (1998). Fibroblast growth factor receptors: lessons from the genes. Trends Biochem. Sci. 23, 59-62.
5. Casai, J., and Leptin, M. (1996). Identification of novel genes in Drosophila reveals the complex regulation of early gene activity in the mesoderm. Proc. Natl. Acad. Sci. USA 93, 10327-10332.
6. Celli, G., LaRochelle, W.J., Mackem, S., Sharp, R., and Merlino, G. (1998). Soluble dominant-negative receptor uncovers essential roles for fibroblast growth factors in multi-organ induction and patterning. EMBO J. 17, 1642-1655.
7. Deák, P., Omar, M.M., Saunders, R.D., Pál, M., Komonyi, O., Szidonya, J., Maróy, P., Zhang, Y., Ashburner, M., Benos, P., et al. (1997). P-element insertion alleles of essential genes on the third chromosome of Drosophila melanogaster: correlation of physical and cytogenetic maps in chromosomal region 86E-87F. Genetics 147, 1697-1722.
8. Dickson, B., and Hafen, E. (1993). Genetic dissection of eye development in Drosophila. In The Development of Drosophila melanogaster, M. Bate and A. Martinez Arias, eds. (Plainview, N.Y.: Cold Spring Harbor Laboratory Press), pp. 1327-1362.
9. Dickson, B., Sprenger, F., Morrison, D., and Hafen, E. (1992). Raf functions downstream of Ras1 in the sevenless signal transduction pathway. Nature 360, 600-603.
10. Fortini, M.E., Simon, M.A., and Rubin, G.M. (1992). Signalling by the Sevenless protein tyrosine kinase is mimicked by Ras1 activation. Nature 355, 559-561.
11. Gabay, L., Seger, R., and Shilo, B.Z. (1997a). In situ activation pattern of Drosophila EGF receptor pathway during development. Science 277, 1103-1106.
12. Gabay, L., Seger, R., and Shilo, B.Z. (1997b). MAP kinase in situ activation atlas during Drosophila embryogenesis. Development 124, 3535-3541.
13. Georgias, C., Wasser, M., and Hinz, U. (1997). A basic-helix-loop-helix protein expressed in precursors of Drosophila longitudinal visceral muscles. Mech. Dev. 69, 115-124.
14. Gisselbrecht, S., Skeath, J.B., Doe, C.Q., and Michelson, A.M. (1996). heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. Genes Dev. 10, 3003-3017.
15. Gorina, S., and Pavletich, N.P. (1996). Structure of the p53 tumor suppressor bound to the ankyrin and SH3 domains of 53BP2. Science 274, 1001-1005.
16. Guillemin, K., Groppe, J., Dücker, K., Treisman, R., Hafen, E., Affolter, M., and Krasnow, M.A. (1996). The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122, 1353-1362.
17. Häcker, U., Kaufmann, E., Hartmann, C., Jürgens, G., Knöchel, W., and Jäckle, H. (1995). The Drosophila fork head domain protein crocodile is required for the establishment of head structures. EMBO J. 14, 5306-5317.
18. Hacohen, N., Kramer, S., Sutherland, D., Hiromi, Y., and Krasnow, M.A. (1998). sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92, 253-263.
19. Herbst, R., Carroll, P.M., Allard, J.D., Schilling, J., Raabe, T., and Simon, M.A. (1996). Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling. Cell 85, 899-909.
20. Karpen, G.H., and Spradling, A.C. (1992). Analysis of subtelomeric heterochromatin in the Drosophila minichromosome Dpi 187 by single P element insertional mutagenesis. Genetics 132, 737-753.
21. Klämbt, C., Glazer, L., and Shilo, B.Z. (1992). breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes Dev. 6, 1668-1678.
22. Klemke, R.L., Cai, S., Giannini, A.L., Gallagher, P.J., de Lanerolle, P., and Cheresh, D.A. (1997). Regulation of cell motility by mitogen-activated protein kinase. J. Cell Biol. 137, 481-492.
23. Klint, P., Kanda, S., and Claesson-Welsh, L. (1995). She and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells. J. Biol. Chem. 270, 23337-23344.
24. Kouhara, H., Hadari, Y.R., Spivak-Kroizman, T., Schilling, J., BarSagi, D., Lax, I., and Schlessinger, J. (1997). A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89, 693-702.
25. Kühnlein, R.P., and Schuh, R. (1996). Dual function of the region-specific homeotic gene spalt during Drosophila tracheal system development. Development 122, 2215-2223.
26. Kuriyan, J., and Cowburn, D. (1997). Modular peptide recognition domains in eukaryotic signaling. Annu. Rev. Biophys. Biomol. Struct. 26, 259-288.
27. Lee, T., Hacohen, N., Krasnow, M., and Montell, D.J. (1996). Regulated Breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system. Genes Dev. 10, 2912-2921.
28. Lu, X., Chou, T.B., Williams, N.G., Roberts, T., and Perrimon, N. (1993). Control of cell fate determination by p21 ras/Ras1, an essential component of torso signaling in Drosophila. Genes Dev. 7, 621-632.
29. Luh, F.Y., Archer, S.J., Domaille, P.J., Smith, B.O., Owen, D., Brotherton, D.H., Raine, A.R., Xu, X., Brizuela, L., Brenner, S.L., and Laue, E.D. (1997). Structure of the cyclin-dependent kinase inhibitor p19Ink4d. Nature 389, 999-1003.
30. Lupas, A. (1996). Prediction and analysis of coiled-coil structures. Methods Enzymol. 266, 513-525.
31. Michelson, A.M., Gisselbrecht, S., Zhou, Y., Baek, K.-H., and Buff, E.M. (1998). Dual functions of the Heartless fibroblast growth factor receptor in development of the Drosophila embryonic mesoderm. Dev. Genet. 22, 212-229.
32. Montagne, J., Groppe, J., Guillemin, K., Krasnow, M.A., Gehring, W.J., and Affolter, M. (1996). The Drosophila Serum Response Factor gene is required for the formation of intervein tissue of the wing and is allelic to blistered. Development 122, 2589-2597.
33. Pawson, T. (1995). Protein modules and signaling networks. Nature 373, 573-580.
34. Pawson, T., and Scott, J.D. (1997). Signaling through scaffold, anchoring, and adaptor proteins. Science 278, 2075-2080.
35. Raabe, T., Riesgo-Escovar, J., Liu, X., Bausenwein, B.S., Deák, P., Maróy, P., and Hafen, E. (1996). DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between Sevenless and Ras1 in Drosophila. Cell 85, 911-920.
36. Reichman-Fried, M., Dickson, B., Hafen, E., and Shilo, B.Z. (1994). Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration. Genes Dev. 8, 428-439.
37. Schlessinger, J. (1994). SH2/SH3 signaling proteins. Curr. Opin. Genet. Dev. 4, 25-30.
38. Shiga, Y., Tanaka-Matakatsu, M., and Hayashi, S. (1996). A nuclear GFP beta-galactosidase fusion protein as a marker for morphogenesis in living Drosophila. Dev. Growth Diffn. 38, 99-106.
39. Shishido, E., Ono, N., Kojima, T., and Saigo, K. (1997). Requirements of DFR1/Heartless, a mesoderm-specific Drosophila FGF-receptor, for the formation of heart, visceral and somatic muscles, and ensheathing of longitudinal axon tracts in CNS. Development 124, 2119-2128.
40. Sutherland, D., Samakovlis, C., and Krasnow, M.A. (1996). branchless encodes a Drosophila FGF homolog that controls tracheal cell migration and the pattern of branching. Cell 87, 1091-1101.
41. Tamkun, J.W., Deuring, R., Scott, M.P., Kissinger, M., Pattatucci, A.M., Kaufman, T.C., and Kennison, J.A. (1992). brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68, 561-572.
42. Tautz, D., and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
43. Wang, J.K., Xu, H., Li, H.C., and Goldfarb, M. (1996). Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras. Oncogene 13, 721-729.
44. Wassarman, D.A., Therrien, M., and Rubin, G.M. (1995). The Ras signaling pathway in Drosophila. Curr. Opin. Genet. Dev. 5, 44-50.
45. Webster, M.K., and Donoghue, D.J. (1997). FGFRactivation in skeletal disorders: too much of a good thing. Trends Genet. 13, 178-182.
46. Yung, Y., Dolginov, Y., Yao, Z., Rubinfeld, H., Michael, D., Hanoch, T., Roubini, E., Lando, Z., Zharhary, D., and Seger, R. (1997). Detection of ERK activation by a novel monoclonal antibody. FEBS Lett. 408, 292-296.
47. Zetter, B.R. (1998). Angiogenesis and tumor metastasis. Annu. Rev. Med. 49, 407-424.