Regulated breathless receptor tyrosine kinase activity required to pattern cell migration and branching in the Drosophila tracheal system

Genes and Development

Volumn 10, Issue 22, 1996, Pages 2912-2921

  Lee, Tzumin ^a   Hacohen, Nir ^b   Krasnow, Mark ^b   Montell, Denise J ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

branching morphogenesis; Cell migration; receptor tyrosine kinase

Indexed keywords

PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRACHEA;

ANIMALIA;

EID: 0029832043     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.10.22.2912     Document Type: Article

References (28)

1. Basler, K., B. Christen, and E. Hafen. 1991. Ligand-independent activation of the sevenless receptor tyrosine kinase changes the fate of cells in the developing Drosophila eye. Cell 64: 1069-1081.
2. Bladt, F., D. Riethmacher, S. Isenmann, A. Aguzzi, and C. Birchmeier. 1995. Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud. Nature 376: 768-771.
3. Brand, A.H. and Perrimon, N. 1994. Raf acts downstream of the EGF receptor to determine dorsoventral polarity during Drosophila oogenesis. Genes & Dev. 8: 629-639.
4. Brunner, D., N. Oellers, J. Szabad, W.H. Biggs III, S.L. Zipursky, and E. Hafen. 1994. A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways. Cell 76: 875-888.
5. Callahan, C.A., M.G. Muralldhar, S.E. Lundgren, A.L. Scully, and J.B. Thomas. 1995. Control of neuronal pathway selection by a Drasophila receptor protem-tyrosine kinase family member. Nature 376: 171-174.
6. Cheng, H-J., M. Nakamoto, A.D. Bergemann, and J.G. Flanagan. 1995. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell 82: 371-382.
7. DeVore, D.L., H.R. Horvitz, and M.J. Stern. 1995. An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites. Cell 83: 611-620.
8. Dickson, B., F. Sprenger, and E. Hafen. 1996. Prepattern in the developing Drosophila eye revealed by an activated torsosevenless chimeric receptor. Genes & Dev. 6: 2327-2339.
9. Dikic, I., J. Schlessinger, and I. Lax. 1994. PC12 cells overexpressing the insulin receptor undergo insulin-dependent neuronal differentiation. Curr. Biol. 4: 702-708.
10. Drescher, U., C. Kremoser, C. Handwerker, J. Loschinger, M. Noda, and F. Bonhoeffer. 1995. In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell 82: 359-370.
11. Fantl, W.J., D.E. Johnson, and L.T. Williams. 1993. Signalling by receptor tyrosine kinases. Annu. Rev. Biochem. 62: 453-481.
12. Fleischman, R.A. 1993. From white spots to stem cells: the role of the Kit receptor in mammalian development. Trends Genet. 9: 285-290.
13. Glazer, L. and B.-Z. Shilo. 1991. The Drosophila FGF receptor homolog is expressed in the embryonic tracheal system and appears to be required for directed trachael cell extension. Genes & Dev. 5: 697-705.
14. Guillemin, K., J. Groppe, K. Ducker, R. Treisman, E. Hafen, M. Affolter, and M.A. Krasnow. 1996. The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system. Development 122: 1353-1362.
15. Johnson, G.L. and R.R. Vaillancourt. 1994. Sequential protein kinase reactions controlling cell growth and differentiation. Curr. Biol 6: 230-238.
16. Klambt, C., L. Glazer, and B.Z. Shilo. 1992. breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells. Genes & Dev. 6: 1668-1678.
17. Kundras, V., J.A. Escobedo, A. Kazlauskas, H.K. Kim, S.G. Rhee, L.T. Williams, and B.R. Zetter. 1994. Regulation of chemotaxis by the platelet-derived growth factor receptor-beta. Nature 367: 474-476.
18. Kunkel, T.A., J.D. Roberts, and R.A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154: 367-382.
19. Manning, G. and M.A. Krasnow. 1993. Development of the Drosophila tracheal system. In The development of Drosophila melanogaster. (ed. M. Bate, and A.M. Arias), pp. 609-685. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
20. Montell, D.J. 1994. Moving right along: Regulation of cell migration during Drosophila development. Trends Genet. 10: 59-62.
21. Murphy, A.M., T. Lee, C.M. Andrews, B.Z. Shilo, and D.J. Montell. 1995. The Breathless FGF receptor homolog, a downstream target of Drosophila C/EBP in the developmental control of cell migration. Development 121: 2255-2263.
22. Obermeier, A., R.A. Bradshaw, K. Seedorf, A. Choidas, and J. Schlessinger. 1994. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLCγ. EMBO J. 13: 1585-1590.
23. Reichman-Fried, M. and B.-Z. Shilo. 1995. Breathless, a Drosophila FGF receptor homolog, is required for the onset of tracheal cell migration and tracheole formation. Mechanism of Development 52: 265-273.
24. Reichman-Fried, M., B. Dickson, E. Hafen, and B.Z. Shilo. 1994. Elucidation of the role of breathless, Drosophila FGF receptor homolog, in tracheal cell migration. Genes & Dev. 8: 428-439.
25. Rubin, G.M. and A.C. Spradling. 1982. Genetic transformation of Drosophila with transposable element vectors. Science 218: 348-353.
26. Samakovlis, C., N. Hacohen, G. Manning, D. Sutherland, K. Guillemin, and M.A. Krasnow. 1996. Branching morphogenesis of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events. Development 122: 1395-1407.
27. Schuchardt, A., V. D'Agati, L. Larsson-Blomberg, F. Costantini, and V. Pachnis. 1994a. Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature 367: 380-383.
28. Sutherland, D., C. Samakovlis, and M.A. Krasnow. 1996. branchless encodes a Drosophila fibroblast growth factor homolog that controls tracheal cell migration and branching. Cell (in press).