[[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT(1A) receptor ligands

Journal of Medicinal Chemistry

Volumn 40, Issue 4, 1997, Pages 574-585

  Modica, Maria ^a   Santagati, Maria ^a   Russo, Filippo ^a   Parotti, Luca ^b   De Gioia, Luca ^b   Selvaggini, Carlo ^b   Salmona, Mario ^b   Mennini, Tiziana ^b  

^a UNIVERSITY OF CATANIA   (Italy)

^b MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINO 2 [[3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]PROPYL]THIO] 5,6 DIMETHYLTHIENO[2,3 D]PYRIMIDIN 4(3H) ONE; ALPHA 1 ADRENERGIC RECEPTOR; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 1A RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; DRUG SELECTIVITY; LIGAND BINDING; MALE; NONHUMAN; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT; RECEPTOR AFFINITY;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BINDING, COMPETITIVE; MODELS, CHEMICAL; PIPERAZINES; PYRIMIDINONES; RATS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031052150     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950866t     Document Type: Article

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