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Volumn 57, Issue 7, 1998, Pages 684-689

PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas

Author keywords

MMAC1; Mutation; Primary gtioblastoma; PTEN; Secondary glioblastoma

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR;

EID: 0031840405     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199807000-00005     Document Type: Article
Times cited : (217)

References (33)
  • 1
    • 0029992049 scopus 로고    scopus 로고
    • Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q
    • Albarosa R, Colombo BM, Roz L, et al. Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q. Am J Hum Genet 1996;58:1260-67
    • (1996) Am J Hum Genet , vol.58 , pp. 1260-1267
    • Albarosa, R.1    Colombo, B.M.2    Roz, L.3
  • 2
    • 0028087884 scopus 로고
    • Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors
    • Lang FF, Miller DC, Koslow M, Newcomb EW. Pathways leading to glioblastoma multiforme: A molecular analysis of genetic alterations in 65 astrocytic tumors. J Neurosurg 1994;81:427-36
    • (1994) J Neurosurg , vol.81 , pp. 427-436
    • Lang, F.F.1    Miller, D.C.2    Koslow, M.3    Newcomb, E.W.4
  • 3
    • 0027167694 scopus 로고
    • Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme
    • Fults D, Pedone C. Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme. Genes Chromosom Cancer 1993;7:173-77
    • (1993) Genes Chromosom Cancer , vol.7 , pp. 173-177
    • Fults, D.1    Pedone, C.2
  • 5
    • 0029024891 scopus 로고
    • Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25
    • Rasheed BK, McLendon RE, Friedman HS, et al. Chromosome 10 deletion mapping in human gliomas: A common deletion region in 10q25. Oncogene 1995;10:2243-46
    • (1995) Oncogene , vol.10 , pp. 2243-2246
    • Rasheed, B.K.1    McLendon, R.E.2    Friedman, H.S.3
  • 6
    • 0030910239 scopus 로고    scopus 로고
    • A molecular genetic model of astrocytoma histopathology
    • Louis DN. A molecular genetic model of astrocytoma histopathology. Brain Pathol 1997;7:755-64
    • (1997) Brain Pathol , vol.7 , pp. 755-764
    • Louis, D.N.1
  • 9
    • 0030936323 scopus 로고    scopus 로고
    • PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
    • Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-47
    • (1997) Science , vol.275 , pp. 1943-1947
    • Li, J.1    Yen, C.2    Liaw, D.3
  • 10
    • 17144436629 scopus 로고    scopus 로고
    • Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
    • Steck PA, Pershouse MA, Jasser SA, et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nature Genet 1997; 15:356-62
    • (1997) Nature Genet , vol.15 , pp. 356-362
    • Steck, P.A.1    Pershouse, M.A.2    Jasser, S.A.3
  • 12
    • 0030799909 scopus 로고    scopus 로고
    • Somatic mutations of PTEN in glioblastoma multiforme
    • Wang SI, Pue J, Li J, et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 1997;57:4183-86
    • (1997) Cancer Res , vol.57 , pp. 4183-4186
    • Wang, S.I.1    Pue, J.2    Li, J.3
  • 13
    • 0030817576 scopus 로고    scopus 로고
    • PTEN gene mutations are seen in high-grade but not in low-grade gliomas
    • Rasheed BKA, Stenzel TT, McLendon RE, et al. PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 1997;57:4187-90
    • (1997) Cancer Res , vol.57 , pp. 4187-4190
    • Rasheed, B.K.A.1    Stenzel, T.T.2    McLendon, R.E.3
  • 14
    • 7144223432 scopus 로고    scopus 로고
    • PTEN mutations in gliomas and glioneuronal tumors
    • Forthcoming
    • Duerr E-M, Rollbrocker B, Hayashi Y, et al. PTEN mutations in gliomas and glioneuronal tumors. Oncogene 1998. Forthcoming.
    • (1998) Oncogene
    • Duerr, E.-M.1    Rollbrocker, B.2    Hayashi, Y.3
  • 17
    • 84949655795 scopus 로고
    • Cerebral astrocytomas and their derivatives
    • Scherer HJ. Cerebral astrocytomas and their derivatives. Am J Cancer 1940;40:159-98
    • (1940) Am J Cancer , vol.40 , pp. 159-198
    • Scherer, H.J.1
  • 22
    • 0030017885 scopus 로고    scopus 로고
    • Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
    • Watanabe K, Tachibana O, Sato K, Yonekawa Y, Kleihues P, Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 1996;6:217-24
    • (1996) Brain Pathol , vol.6 , pp. 217-224
    • Watanabe, K.1    Tachibana, O.2    Sato, K.3    Yonekawa, Y.4    Kleihues, P.5    Ohgaki, H.6
  • 23
    • 0030778862 scopus 로고    scopus 로고
    • Amplification and Overexpression of MDM2 in primary (de novo) glioblastomas
    • Biernat W, Kleihues P, Yonekawa Y, Ohgaki H. Amplification and Overexpression of MDM2 in primary (de novo) glioblastomas. J Neuropathol Exp Neurol 1996;56:180-85
    • (1996) J Neuropathol Exp Neurol , vol.56 , pp. 180-185
    • Biernat, W.1    Kleihues, P.2    Yonekawa, Y.3    Ohgaki, H.4
  • 24
    • 0030881477 scopus 로고    scopus 로고
    • Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas
    • Biernat W, Tohma Y, Yonekawa Y, Kleihues P, Ohgaki H. Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas. Acta Neuropathol 1997;94:303-9
    • (1997) Acta Neuropathol , vol.94 , pp. 303-309
    • Biernat, W.1    Tohma, Y.2    Yonekawa, Y.3    Kleihues, P.4    Ohgaki, H.5
  • 25
    • 0028832159 scopus 로고
    • Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue
    • Hunter SB, Abbott K, Varma VA, Olson JJ, Barnett DW, James CD. Reliability of differential PCR for the detection of EGFR and MDM2 gene amplification in DNA extracted from FFPE glioma tissue. J Neuropathol Exp Neurol 1995;54:57-64
    • (1995) J Neuropathol Exp Neurol , vol.54 , pp. 57-64
    • Hunter, S.B.1    Abbott, K.2    Varma, V.A.3    Olson, J.J.4    Barnett, D.W.5    James, C.D.6
  • 26
    • 0029897610 scopus 로고    scopus 로고
    • Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme
    • Rollbrocker B, Waha A, Louis DN, Wiestler OD, von Deimling A. Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme. Acta Neuropathol 1996;92:70-74
    • (1996) Acta Neuropathol , vol.92 , pp. 70-74
    • Rollbrocker, B.1    Waha, A.2    Louis, D.N.3    Wiestler, O.D.4    Von Deimling, A.5
  • 27
    • 0030837555 scopus 로고    scopus 로고
    • P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
    • Myers MP, Stolarov JP, Eng C, et al. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci USA 1997;94:9052-57
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 9052-9057
    • Myers, M.P.1    Stolarov, J.P.2    Eng, C.3
  • 28
    • 0028956756 scopus 로고
    • Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin
    • Chuang JZ, Lin DC, Lin S. Molecular cloning, expression, and mapping of the high affinity actin-capping domain of chicken cardiac tensin. J Cell Biol 1995;128:1095-1109
    • (1995) J Cell Biol , vol.128 , pp. 1095-1109
    • Chuang, J.Z.1    Lin, D.C.2    Lin, S.3
  • 29
    • 0028801218 scopus 로고
    • Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules
    • Miyamoto S, Teramoto H, Coso OA, et al. Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules. J Cell Biol 1995;131:791-805
    • (1995) J Cell Biol , vol.131 , pp. 791-805
    • Miyamoto, S.1    Teramoto, H.2    Coso, O.A.3
  • 30
    • 0028954797 scopus 로고
    • Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
    • Miyamoto S, Akiyama SK, Yamada KM. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function. Science 1995;267:883-85
    • (1995) Science , vol.267 , pp. 883-885
    • Miyamoto, S.1    Akiyama, S.K.2    Yamada, K.M.3
  • 31
    • 0026710064 scopus 로고
    • Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme
    • von Deimling A, Louis DN, von Ammon K, et al. Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme. J Neurosurg 1992;77:295-301
    • (1992) J Neurosurg , vol.77 , pp. 295-301
    • Von Deimling, A.1    Louis, D.N.2    Von Ammon, K.3
  • 32
    • 0030879478 scopus 로고    scopus 로고
    • DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours
    • Mollenhauer J, Wiemann S, Scheurlen W, et al. DMBT1, a new member of the SRCR superfamily, on chromosome 10q25.3-26.1 is deleted in malignant brain tumours. Nat Genet 1997;17:32-39
    • (1997) Nat Genet , vol.17 , pp. 32-39
    • Mollenhauer, J.1    Wiemann, S.2    Scheurlen, W.3
  • 33
    • 0026547577 scopus 로고
    • p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression
    • Fults D, Brockmeyer D, Tullous MW, Pedone CA, Cawthon RM. p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression. Cancer Res 1992;52: 674-79
    • (1992) Cancer Res , vol.52 , pp. 674-679
    • Fults, D.1    Brockmeyer, D.2    Tullous, M.W.3    Pedone, C.A.4    Cawthon, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.