Allelic loss of the BRCA1 and BRCA2 genes and other regions on 17q and 13q in breast cancer among women from Taiwan (area of low incidence but early onset)

International Journal of Cancer

Volumn 79, Issue 6, 1998, Pages 580-587

  Lo, Yen Li ^a,b   Yu, Jyh Cherng ^c   Huang, Chiun Sheng ^d   Tseng, Su Ling ^a   Chang, Tzu Ming ^c,e   Chang, King Jen ^d   Wu, Cheng Wen ^a,f   Shen, Chen Yang ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^e BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^f NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; BREAST CANCER; CANCER GENETICS; CANCER SUSCEPTIBILITY; CHROMOSOME 13Q; CHROMOSOME 17Q; FEMALE; GENE LOSS; GENETIC SUSCEPTIBILITY; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; ONCOGENE; PRIORITY JOURNAL; TAIWAN;

AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; GENES, BRCA1; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; TAIWAN; TRANSCRIPTION FACTORS; TREATMENT OUTCOME;

EID: 0031793995     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19981218)79:6<580::AID-IJC5>3.0.CO;2-M     Document Type: Article

References (45)

1. BIÉCHE, I. and LIDEREAU, R., Genetic alterations in breast cancer. Genes Chromosomes Cancer, 14, 227-251 (1995).
2. BORG, Å., ZHANG, Q.X., ALM, P., OLSSON, H. and SELLBERG, G., The retinoblastoma gene in breast cancer: allele loss is not correlated with loss of gene protein expression. Cancer Res., 52, 2991-2994 (1992).
3. BREAST CANCER LINKAGE CONSORTIUM, Pathology of familial breast cancer: differences between breast cancers in carriers of BRCA1 or BRCA2 mutations and sporadic cases. Lancet, 349, 1505-1510 (1997).
4. CHEN, Y., CHEN, C.F., RILEY, D.J., ALLRED, D.C., CHEN, P.L., VON HOFF, D., OSBORNE, C.K. and LEE W.H., Aberrant subcellular localization of BRCA1 in breast cancer. Science, 270, 789-791 (1995).
5. COLONS, N., MCMANUS, R., WOOSTER, R., MANGION, J., SEAL, S., LAKHANI, S.R., ORMISTON, W., DALY, P.A., FORD, D., EASTON, D.F. and STRATTON, M.R., Consistent loss of the wild type allele in breast cancers from a family linked to the BRCA2 gene on chromosome 13q12-13. Oncogene, 10, 1673-1675 (1995).
6. CORNELIS, R.S., DEVILEE, P., VAN VLIET, M., KUIPERS-DIJKSHOORN, N., KERSENMAEKER, A., BARDOEL, A., KHAN, P.M. and CORNELISSE, C.J. Allele loss patterns on chromosome 17q in 109 breast carcinomas indicate at least two distinct target regions. Oncogene, 8, 781-785 (1993).
7. CORNELIS, R.S. and 21 OTHERS, High allele loss rates at 17q12-q21 in breast cancer and ovarian tumors from BRCA1-linked families. Genes Chromosomes Cancer, 13, 203-210 (1995).
8. COUCH, F.J. and 41 OTHERS, Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. Genomics, 36, 86-99 (1996).
9. CROPP, C.S., LIDEREAU, R., CAMPBELL, G., CHAMPÉME, M.H. and CALLAHAN, R., Loss of heterozygosity on chromosomes 17 and 18 in breast cancer carcinoma: two additional regions identified. Proc. nat. Acad. Sci. (Wash.), 87, 7737-7741 (1990).
10. DOBROVIC, A. and SIMPFENDORFER, D., Methylation of the BRCA1 gene in sporadic breast cancer. Cancer Res., 57, 3347-3350 (1997).
11. EASTON, D.F., BISHOP, D.T., FORD, D., CROCKFORD, G.P. and THE BREAST CANCER LINKAGE CONSORTIUM, Genetic linkage analysis in familial breast and ovarian cancer - results from 214 families. Amer. J. hum. Genet., 52, 678-701 (1993).
12. FUTREAL, P.A. and 26 OTHERS, BRCA1 mutations in primary breast and ovarian carcinomas. Science, 266, 120-122 (1994).
13. GYAPAY, G., MORISSETTE, J., VIGNAL, A., DIB, C., FIZAMES, C., MILLASSEAU, P., MARC, S., BERNARDI G., LATHROP, M. and WEISSENBACH, J., The 1993-94 Généthon human genetic linkage map. Nature (Genet.), 7, 246-339 (1994).
14. HAMANN, U., HERBOLD, C., COSTA, S., SOLOMAYER, E.F., KAUFMANN, M., BASTERT, G., ULMER, H.U., FRENZEL, H. and KOMITOWSKI, D., Allelic imbalance on chromosome 13q: evidence for the involvement of BRCA2 and RB1 in sporadic breast cancer. Cancer Res., 56, 1988-1890 (1996).
15. HOLT, J.T., THOMPSON, M.E., SZABO, C., ROBINSON-BENION, C., ARTEAGA, C.L., KING, M.C. and JENSEN, R.A., Growth retardation and tumour inhibition by BRCA1. Nature (Genet.), 12, 298-302 (1996).
16. HULKA, B.S. and STARK, A.T., Breast cancer: cause and prevention. Lancet, 346, 883-887 (1995).
17. KNUDSON, A.G., Hereditary cancers: clues to mechanisms of carcinogenesis. Brit. J. Cancer, 59, 661-666 (1989).
18. KORETH, J., BAKKENIST, CJ. and MCGEE, J.O'D., Allelic deletions at chromosome 11q22-q23.1 and 11q25-qterm are frequent in sporadic breast but not colorectal cancers. Oncogene, 14, 431-437 (1997).
19. KU, W.H., LIU, I.L., YEN, M.S., CHANG CHIEN, C.C., YUE, C.T., MA, Y.Y., CHANG, S.F., NG, H.T., WU, C.W. and SHEN, C.Y., Genetic deletion and p53 inactivation in cervical carcinoma. Int. J. Cancer, 72, 270-276 (1997).
20. LASKO, D., CAVENEE, W. and NORDENSKJÖLD, M. Loss of constitutional heterozygosity in human cancer. Ann. Rev. Genet., 25, 281-314 (1991).
21. LOU, M.A., TSENG, S.L., CHANG, S.F., YUE, C.T., CHANG, B.L., CHOU, C.H., YANG, S.L., TEH, B.H., WU, C.W. and SHEN, C.Y., Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low incidence area. Brit. J. Cancer, 75, 746-751 (1997).
22. MALINS, D.C., HOLMES, E.H., POLISSAR, N.L. and GUNSELMAN, S.J., The etiology of breast cancer. Characteristic alteration in hydroxyl radical-induced DNA base lesions during oncogenesis with potential for evaluating incidence risk. Cancer, 71, 3036-3043 (1993).
23. MIKI, Y. and 44 OTHERS, A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science, 266, 66-71 (1994).
24. NEUHAUSEN, S.L. and MARSHALL, C.J., Loss of heterozygosity in familial tumors from three BRCA1-kindreds. Cancer Res., 54, 6069-6072 (1994).
25. NEUHAUSEN, S.L. and 19 OTHERS, A P1-based physical map of the region from D17S776 to D17S78 containing the breast cancer susceptibility gene BRCA1. Hum. mol. Genet., 3, 1919-1926 (1994).
26. NIEDERACHER, D., PICARD, F., VAN ROEYEN, C., AN, H.X., BENDER, H.G. and BECKMANN, M.W., Patterns of allelic loss on chromosome 17 in sporadic breast carcinomas detected by fluorescent-labeled microsatellite analysis. Genes Chromosomes Cancer, 18, 181-192 (1997).
27. PANDIS, N., BARDI G., MITELMAN, F. and HEIM, S., Deletion of the short arm of chromosome 3 in breast tumors. Genes Chromosomes Cancer, 18, 241-245 (1997).
28. + tumor cells. Cell, 75, 1227-1236 (1993).
29. RADFORD, D.M., FAIR, K.L., PHILLIPS, N.J., RITTER, J.H., STEINBRUECK, T., HOLT, M.S. and DONIS-KELLER, H., Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q. Cancer Res., 55, 3399-3405 (1995).
30. SCHOTT, D.R., CHANG, J.N., DENG, G., KURISU, W., KUO, W.L., GRAY, J. and SMITH, H.S., A candidate tumor suppressor gene in human breast cancer. Cancer Res., 54, 1393-1396 (1994).
31. SLAMON, D.J., CLARK, G.M., WONG, S.G., LEVIN, W.J., ULLRICH, A. and MCGUIRE, W.L., Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science, 235, 177-182 (1987).
32. STRACHAN, T. and READ, A.P., Human molecular genetics, pp. 51-59, Wiley-Liss, New York (1996).
33. STRATTON, M.R., COLLINS, N., LAKHANI, S.R. and SLOANE, J.P., Loss of heterozygosity in ductal carcinoma in situ of the breast. J. Pathol., 175, 195-201 (1995).
34. TENG, D.H-F. and 27 OTHERS, MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res., 57, 5221-5225 (1997).
35. THEILE, M., HARTMANN, S., SCHERTHAN, H., ARNOLD, W., DEPPERT, W., FREGE, R., GLAAB, F., HAENSCH, W. and SCHERNECK, S., Suppression of tumorigenicity of breast cancer cells by transfer of human chromosome 17 does not require transferred BRCA1 and p53 genes. Oncogene, 10, 439-447 (1995).
36. THOMPSON, M.E., JENSEN, R.A., OBERMILLER, P.S., PAGE, D.L. and HOLT, J.T., Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nature (Genet.), 9, 444-450 (1995).
37. TOGUCHIDA, I., MCGEE, T.L., PATERSON, J.C., EAGLE, J.R., TUCKER, S., YANDELL, D.W. and DRYJA, T.P., Complete genomic sequence of the human retinoblastoma susceptibility gene. Genomics, 17, 535-543 (1993).
38. TROJANI, M., A color atlas of breast histopathology, Chapman and Hall, London (1991).
39. TSENG, S.L., YU, J.C., YUE, C.T., CHANG, S.F., CHANG, T.M., WU, C.W. and SHEN, C.Y., Allelic loss at BRCA1 , BRCA2 and adjacent loci in relation to TP53 abnormality in breast cancer. Genes Chromosomes Cancer, 20, 377-382 (1997).
40. TSUKAMOTO, K., ITO, N., YOSHIMOTO, M., IWASE, T., TADA, T., KASUMI, F., NAKAMURA, Y. and EMI, M., Two distinct commonly deleted regions on chromosome 13q suggest the involvement of BRCA2 and retinoblastoma genes in sporadic breast carcinomas. Cancer, 78, 1929-1934 (1996).
41. VAN DEN BERG, J., JOHANNSSON, O., HÅKANSSON, S., OLSSON, H. and BORG, Å., Allelic loss at chromosome 13q 12-q 13 is associated with poor prognosis in familial and sporadic breast cancer. Brit. J. Cancer, 74, 1615-1619 (1996).
42. WINDLE. B., DRAPER, B.W., YIN, Y.X., O'GORMAN, S. and WAHL, G.M., A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration. Genes Develop., 5, 160-174 (1991).
43. WOOSTER, R. and 30 OTHERS, Localization of a breast cancer susceptibility gene, BRCA2 , to chromosome 13q12-13. Science, 265, 2088-2090 (1994).
44. WOOSTER, R. and 40 OTHERS, Identification of the breast cancer susceptibility gene BRCA2 . Nature, 378, 789-792 (1995).
45. YANG, P.S., YANG, T.L., LIU, C.L., WU, C.W. and SHEN, C.Y., A case control study of breast cancer in Taiwan - a low incidence area. Brit. J. Cancer, 75, 752-756 (1997).