Allelic loss at BRCA1, BRCA2, and adjacent loci in relation to TP53 abnormality in breast cancer

Genes Chromosomes and Cancer

Volumn 20, Issue 4, 1997, Pages 377-382

  Tseng, Su Ling ^a   Yu, Jyh Cherng ^b   Yue, Chung Tai ^c   Chang, Shu Fen ^a   Chang, Tzu Ming ^b,d   Wu, Cheng Wen ^a   Shen, Chen Yang ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^c TAIWAN ADVENTIST HOSPITAL   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ALLELE; ARTICLE; BREAST CANCER; CANCER SUSCEPTIBILITY; CARCINOGENESIS; FEMALE; GENE DELETION; GENE LOCUS; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALIGNANT TRANSFORMATION; PRIORITY JOURNAL;

ADULT; AGED; BRCA2 PROTEIN; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 17; DNA, NEOPLASM; GENE DELETION; GENES, BRCA1; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MIDDLE AGED; MUTATION; NEOPLASM PROTEINS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TRANSCRIPTION FACTORS;

EID: 0030694274     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199712)20:4<377::AID-GCC9>3.0.CO;2-Z     Document Type: Article

References (22)

1. Bièche I, Lidereau R (1995) Genetic alterations in breast cancer. Genes Chromosomes Cancer 14:227-251.
2. Cho KR, Hedrick L (1997) Genetic alterations in human tumors, In Kastan MB (ed): Genetic Instability and Tumorigenesis. Berlin: Springer, pp 149-176.
3. Davidoff AM, Kerns BJ, Iglehart JD, Marks JR (1991) Maintenance of p53 alterations throughout breast cancer progression. Cancer Res 51:2605-2610.
4. 1 arrest and apoptosis. Cancer Res 54:1169-1174.
5. Eyfjörd JE, Thorlacius S, Steinarsdottir M, Valgardsdottir R, Ögmundsdottir HM, Anamthawat-Jonsson K (1995) p53 abnormalities and genomic instability in primary human breast carcinomas. Cancer Res 55:646-651.
6. Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878.
7. Gyapay G, Morissette J, Yignal A, Dib C, Fizames C, Millasseau P, Marc S, Bernardi G, Lathrop M, Weissenbach J (1994) The 1993-94 Généthon human genetic linkage map. Nat Genet 7:246-339.
8. Hall PA, Lane DP (1994) p53 in tumor pathology: can we trust immunohistochemistry? - revisited. J Pathol 172:1-4.
9. Hartmann A, Blaszyk H, Kovach JS, Sommer SS (1997) The molecular epidemiology of p53 gene mutations in human breast cancer. Trend Genet 13:27-32.
10. Holt JT, Thompson ME, Szabo C, Robinson-Benion C, Arteaga CL, King MC, Jensen RA (1996) Growth-retardation and tumor-inhibition by BRCA1. Nat Genet 12:298-302.
11. Kleinbaum DG, Klupper LL, Morgenstern H (1982) Epidemiologic Research. New York: Van Nostrand Reinhold Company.
12. Knudson AG, Jr (1971) Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823.
13. Ku WH, Liu IL, Yen MS, Chang-Chin CC, Yue CT, Ma YY, Chang SF, Ng HT, Wu CW, Shen CY (1997) Genomic deletion and p53 inactivation in cervical carcinoma. Int J Cancer 72:270-276.
14. Loeb LA (1994) Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 54:5059-5063.
15. Lou MA, Tseng SL, Chang SF, Yue CT, Chang BL, Chou CH, Yang SL, Teh BH, Wu CW, Shen CY (1997) Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low incidence area. Br J Cancer 75:746-751.
16. Miki V, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Liu Q, Cochran C, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey C, Tran T, McClure M, Frye C, Hattier T, Phelps R, Hatigen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bogden R, Dayananth P, Ward J, Tonin P, Narod S, Bristow PK, Norris FH, Helvering L, Morrison P, Rosteck P, Lai M, Barrett JC, Lewis C, Neuhausen S, Cannon-Albright L, Goldgar D, Wiseman R, Kamb A, Skolnick MH (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266:66-71.
17. Moll UM, Riou G, Levine AJ (1992) Two distinct mechanisms alter p53 in breast cancer: mutation and nuclear exclusion. Proc Natl Acad Sci USA 89:7262-7266.
18. Pines J (1994) Cell cycle: p21 inhibits cyclin shock. Nature 369:520-521.
19. Radford DM, Fair KL, Phillips NJ, Ritter JH, Steinbrueck T, Holt MS, Donis-Keller HR (1995) Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q. Cancer Res 55:3399-3405.
20. Strachan T, Read AP (1996) Human Molecular Genetics, New York: Wiley-Liss.
21. Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mansion J, Collins N, Gregory S, Gumbs C, Micklem G, Barfoot R, Hamoudi R, Patel S, Rice C, Biggs P, Hashim Y, Smith A, Connor F, Arason A, Gudmundsson J, Ficenec D, Kelsell D, Ford D, Tonin P, Bishop DT, Spurr NK, Ponder BAJ, Eeles R, Peto J, Devilee P, Cornelisse C, Lynch H, Narod S, Lenoir G, Egilsson V, Barkadottir RB, Eastern DF, Bentley DR, Futreal PA, Ashworth A, Stratton MR (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature 378:789-792.
22. Yin Y, Tainsky MA, Bischoff FZ, Strong LC, Wahl GM (1992) Wide-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell 70:937-948.