Patterns of allelic loss on chromosome 17 in sporadic breast carcinomas detected by fluorescent-labeled microsatellite analysis

Genes Chromosomes and Cancer

Volumn 18, Issue 3, 1997, Pages 181-192

  Niederacher, Dieter ^a,b,d   Picard, Frauke ^a,b   Van Roeyen, Claudia ^a,b   An, Han Xiang ^a,b,c   Bender, Hans Georg ^a,b   Beckmann, Matthias Wilhelm ^a,b  

^a Dept of Obstetrics and Gynecology ^*  (Germany)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^d UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; ESTROGEN RECEPTOR; MICROSATELLITE DNA; PROGESTERONE RECEPTOR;

ARTICLE; BENIGN TUMOR; BREAST CARCINOMA; CHROMOSOME 17; CHROMOSOME 17P; CHROMOSOME 17Q; CHROMOSOME DELETION; CONTROLLED STUDY; FLUORESCENCE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE;

EID: 0030891545     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2264(199703)18:3<181::AID-GCC5>3.0.CO;2-Y     Document Type: Article

References (61)

1. Aberle H, Bierkamp C, Torchard D, Serova O, Wagner T, Natt E, Wirsching J, Heidkämper C, Montagna M, Lynch HT, Lenoir GM, Scherer G, Feuteun J, Kemler R (1995) The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers. Proc Natl Acad Sci USA 92:6384-6388.
2. Albertsen HM, Smith SA, Mazoyer S, Fujimoto E, Stevens J, Williams B, Rodriguez P, Cropp CS, Slijepcevic P, Carlson M, Robertson M, Bradley P, Lawrence E, Harrington T, Mei Sheng Z, Hoopes R, Sternberg N, Brothman A, Callahan R, Ponder BAJ, White R (1944) A physical map and candidate genes in the BRCA1 region on chromosome 17q12-21. Nat Genet 7:472-479.
3. Ali IU, Lindereau R, Theillet C, Callahan R (1987) Reduction to homozygosity of genes on chromosome 11 in human breast neoplasia. Science 238:185-188.
4. An HX, Niederacher D, Beckmann MW, Göhring UJ, Scharl A, Picard F, van Roeyen C, Schnürch HG, Bender HG (1945) ERBB2 gene amplification detected by fluorescent differential polymerase chain reaction in paraffin-embedded breast carcinoma tissues. Int J Cancer 64:291-297.
5. Andersen TI, Gaustad A, Ottestad L, Farrants GW, Nesland JM, Tveit KM, Börresen AL (1992) Genetic alterations of the tumour suppressor gene regions 3p, 11p, 13q, 17p, and 17q in human breast carcinomas. Genes Chromosom Cancer 4:113-121.
6. Ausubel FM, Brent R, Moore DD, Seidman JG, Smith JA, Struhl K (1995) Current Protocols in Molecular Biology. New York: John Wiley & Sons, Inc.
7. Beckmann MW, Tutschek B, Krüger KH, Niederacher D, Risse BC, Ruppert C, Schnürch HG, Bender H (1993) Comparison of the biochemical and immunohistochemical detection of the epidermal growth factor receptor (EGF-R) in breast tumor samples. Int J Oncol 3:389-397.
8. Beckmann MW, Picard F, An HX, van Roeyen CRC, Dominik SI, Mosny DS, Schnürch H-G, Bender HG, Niederacher D (1996) Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer. Br J Cancer 73:1220-1226.
9. Bièche I, Champème MH, Matifas F, Hancene K, Callahan R, Lidereau R (1942) Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer. Lancet 339:139-143.
10. Borg A, Zhang QX, Olsson H, Wenngren E (1992) Chromosome 1 alterations in breast cancer: Allelic loss on 1p and 1q is related to lymphogenic metastases and poor prognosis. Genes Chromosom Cancer 5:311-320.
11. Bowcock AM, Anderson LA, Friedman LS, Black DM, Osborne-Lawrence S, Rowell SE, Hall JM, Solomon E, King M-C (1993) THRA1 and D17S185 flank an interval of <4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21. Am J Hum Genet 52:718-722.
12. Chen LC, Dollbaum C, Smith HS (1989) Loss of heterozygosity on chromosome 1q in human breast cancer. Proc Natl Acad Sci USA 86:7204-7207.
13. Coles C, Thompson AM, Elder PA, Cohen BB, MacKenzie IM, Cranston G, Chetty U, MacKay J, MacDonald M, Nakamura Y, Hoyheim B, Steel CM (1990) Evidence implicating at least two genes on chromosome 17p in breast carcinogenesis. Lancet 336:761-763.
14. Coles C, Gondie A, Chetty U, Steel CMm Evans HJ, Prosser J (1992) p53 mutations in breast cancer. Cancer Res 52:5291-5298.
15. Collins FS (1996) BRCA1 - Lots of mutations, lots of dilemmas. N Engl J Med 334:143-149.
16. Cornelis RS, Devilee P, van Vliet M, Kuipers-Dijkshoorn N, Kersenmaeker A, Bardoel A, Meera Khan P, Cornelisse CJ (1993) Allele loss patterns on chromosome 17q in 109 breast carcinomas indicate at least two distinct target regions. Oncogene 8:781-785.
17. Cornelis RS, van Vliet M, Vos CBJ, Cleton-Jansen AM, van deVijver, Peterse JL, Khan PM, Borresen AL, Cornelisse CJ, Devilee PV (1994) Evidence for a gene on 17p13.3 distal to TP53, as a target for allele loss in breast tumors with p53 mutations. Cancer Res 54:4200-4206.
18. Cornelisse C (1992) Loss of heterozygosity, chromosome 7q, and breast cancer. Lancet 339:1423.
19. Cropp CS, Lidereau R, Campbell G, Champème MH, Callahan R (1990) Loss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: Two additional regions identified. Proc Natl Acad Sci USA 87:7737-7741.
20. Cropp CS, Champème MH, Lidereau R, Callahan R (1993) Identification of three regions on chromosome 17q in primary human breast carcinomas which are frequently deleted. Cancer Res 55:5617-5619.
21. Cropp CS, Nevanlinna HA, Pyrhönen S, Stenman U-H, Salmikangas P, Albertsen H, White R, Callahan R (1994) Evidence for involvement of BRCA1 in sporadic breast carcinomas. Cancer Res 54:5617-5619.
22. Devilee P, Cornelisse CJ (1994) Somatic genetic changes in human breast cancer. Biochim Biophys Acta 1198:113-150.
23. Devilee P, Van den Broek M, Kuipers-Dijkshoorn N, Kolluri R, Meera Khan PM, Pearson PL, Cornelisse CJ (1989) At least four different chromosomal regions are involved in loss of heterozygosity in human breast cancer. Genomics 5:554-560.
24. Devilee P, van Vliet M, Kuipers-Dijkshoorn N, Pearson PL, Cornelisse CJ (1991) Somatic genetic changes on chromosome 18 in breast cancer: Is the DCC gene involved? Oncogene 6:311-315.
25. Easton DF, Bishop DT, Ford D, Crockford GP, the Breast Cancer Linkage Consortium (1993) Genetic linkage analysis in familial and ovarian cancer: Results in 214 families. Am J Hum Genet 52:678-701.
26. Eisinger F, Stoppa-Lyonnet D, Longy M, Kerangueven F, Noguchi T, Bailly C, Vincent-Solomon A, Jacquemier J, Birnbaum D, Sobol H (1996) Germ line mutation at the BRCA1 affects the histoprognostic grade in hereditary breast cancer. Cancer Res 56:471-474.
27. Foulkes WD, Black DM, Stamp GWH, Solomon E, Trowsdale J (1993) Very frequent loss of heterozygosity throughout chromosome 17 in sporadic ovarian carcinoma. Int J Cancer 54:220-225.
28. Futreal PA, Söderquist P, Marks JR, Iglehart JD, Cochran C, Barrett JC, Wiseman R (1992) Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms. Cancer Res 52:2624-2627.
29. Futreal PA, Liu Q, Shattuck-Eidens D, Cochran C, Harshman K, Tavtigian S, Bennett LM, Haugen-Strano A, Swensen J, Miki Y, Eddington K, McClure M, Frye C, Weaver-Feldhaus J, Ding W, Gholami Z, Söderquist P, Terry L, Jhanwar S, Berchuck A, Iglehart JD, Marks J, Ballinger DG, Barrett JC, Skolnick MH, Kamb A, Wiseman R (1994) BRCA1 mutations in primary breast cancer and ovarian carcinomas. Science 266:120-122.
30. Genuardi M, Tsihira H, Anderson DE, Saunders GK (1989) Distal deletion of chromosome 1p in ductal carcinoma of the breast. Am J Hum Genet 45:73-82.
31. Goldgar DE, Fields P, Lewis CM, Tran TD, Cannon-Albright LA, Ward JH, Swensen J, Skulnick MH (1994) A large kindred with 17q-linked breast and ovarian cancer: Genetic, phenotypic, and gynecological analysis. J Natl Cancer Inst 86:200-209.
32. Gudmundsson J, Barkardottir RB, Eiriksdottir G, Baldursson T, Arason A, Egilsson V, Ingvarsson S (1995) Loss of heterozygosity at chromosome 11 in breast cancer: Association of prognostic factors with genetic alterations. Br J Cancer 72:696-701.
33. Hampton GM, Mannermaa A, Winqnist R, Alavaikko M, Blanco G, Taskinen PJ, Kiviniemi H, Newsham I, Cavenee WK, Evans GA (1994) Loss of heterozygosity in sporadic human breast carcinoma: A common region between 11q22 and 11q23.3. Cancer Res 54:4586-4589.
34. Holt JT, Thompson ME, Szabo C, Robinson-Benion C, Arteaga CL, King MC, Jensen RA (1996) Growth retardation and tumour growth inhibition by BRCA1. Nat Genet 12:298-302.
35. Hosking L, Trowsdale J, Nicolai H, Solomon E, Foulkes W, Stump G, Signer E, Jeffreys A (1995) A somatic BRCA1 mutation in an ovarian tumour. Nat Genet 9:343-344.
36. Jacobs IJ, Smith SA, Wiseman RW, Futreal PA, Harrington T, Osborne RJ, Leech V, Molyneux A, Berchuck A, Ponder BAJ, Bast RC Jr (1993) A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus. Cancer Res 53:1218-1221.
37. Jacquemier J, Eisinger F, Birnbaum D, Sobol H (1995) Histoptognostic grade in BRCA1-associated breast cancer. Lancet 345:1503.
38. Kirchweger R, Zeilinger R, Schneeberger C, Speiser P, Louason G, Theillet G (1994) Patterns of allele losses suggest the existence of five distinct regions of LOH on chromosome 17 in breast cancer. Int J Cancer 56:193-199.
39. Knudson AG (1971) Mutation and cancer: Statistical study of retinoblastoma. Proc Natl Acad Sci USA 68:820-823.
40. Langston AA, Malone KE, Thompson JD, Daling JR, Ostrander EA (1996) BRCA1 mutations in a population-based sample of young women with breast cancer. N Engl J Med 334:137-142.
41. Leone A, McBride OW, Weston A, Wang MG, Anglard P, Cropp CS, Goebel FR, Lidereau R, Callahan R, Linehan WM, Rees RC, Harris CC, Liotta LA, Steeg PS (1991) Somatic allelic deletion of nm23 in human cancer. Cancer Res 51:2490-2493.
42. Marcus JN, Watson P, Page DL, Narod SA, Lenoir GM, Tonin P, Linder-Stephenson L, Salerno G, Conway TA, Lynch HT (1996) Hereditary breast cancer: Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage. Cancer 77:697-709.
43. Mazars R, Spinardi L, Bencheikh M, Simony-Lafontaine J, Jeanteur P, Theillet C (1992) p53 mutations occur in aggressive breast cancer. Cancer Res 52:3918-3923.
44. Merajver SD, Pham TM, Caduff RF, Chen M, Poy FL, Cooney KA, Weber BL, Collins FS, Johnston C, Frank TS (1995) Somatic mutations in the BRCA1 gene in sporadic ovarian tumours. Nat Genet 9:439-443.
45. Merlo GR, Siddiqui J, Cropp CS, Liscia DS, Lidereau, Callahan R, Kufe DW (1989) Frequent alteration of the DF3 tumor-associated antigen in primary human breast carcinomas. Cancer Res 49:6966-6971.
46. Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, Tavtigian S, Lin Q, Cochran C, Bennett LM, Ding W, Bell R, Rosenthal J, Hussey C, Tran T, McClure M, Frye C, Hattier T, Phelps R, Haugen-Strano A, Katcher H, Yakumo K, Gholami Z, Shaffer D, Stone S, Bayer S, Wray C, Bodgen R, Dayananth P, Ward J, Tonin P, Narod S, Bristow PK, Norris FH, Helvering L, Morrisson P, Rosteck P, Lai M, Barrett JC, Lewis C, Neuhausen S, Cannon-Albright L, Goldgar D, Wiseman R, Kamb A, Skolnick MH (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 266:66-71.
47. Neuhausen SL, Swensen J, Miki Y, Liu Q, Tavtigian S, Shattuck-Eidens D, Kamb A, Hobbs MR, Gingrich J, Shizuya H, Kim U-J, Cochran C, Futreal PA, Wiseman RW, Lynch HT, Tonin P, Narod S, Cannon-Albright L, Skolnick MH, Goldgar DE (1994) A P1-based physical map of the region from D17S776 ro D17S78 containing the breast cancer susceptibility gene BRCA1. Hum Mol Genet 3:1919-1926.
48. Niederacher D, Schnüren HG, An HX, Ellenberger I, Dall P, van Roeven CRC, Küppers V, Beckmann MW (1996) Detection of sequential genetic alterations relevant for breast cancer development. Eur J Cancer Prev 5:497-503.
49. Osborne RJ, Merlo GR, Mitsudomi T, Venesio T, Liscia DS, Cappa AP, Chiba I, Takahashi T, Nau MM, Callahan R, Minna JD (1991) Mutations in the p53 gene in primary human breast cancers. Cancer Res 51:619-4-6198.
50. Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y (1990) Allelotype of breast cancer: Cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50:7184-7189.
51. Sato T, Saito H, Swensen J, Olifant A, Wood C, Danner D, Sakamoto T, Takita K, Kasumi F, Miki Y, Skolnick M, Nakamura Y (1992) The human prohibitin gene located on chromosome 17q21 is mutated in sporadic breast cancer. Cancer Res 52:1043-1646.
52. Shattuck-Eidens D, McClure M, Simard J, Labrie F, Narod S, Couch F, Hoskins K, Weber B, Castilla L, Erdos M, Brody L, Friedman L, Ostermeyer E, Szabo C, King MC, Jhanwar S, Offit K, Norton L, Gilewski T, Lubin M, Osborne M, Black D, Boyd M, Steel M, Ingles S, Haile R, Lindblom A, Olsson H, Borg A, Bishop T, Solomon E, Radice P, Spatti G, Gayther S, Ponder B, Warren W, Stratton M, Liu Q, Fujimura F, Lewis C, Skolnick MH, Goldgar DE, (1995) A collaborative survey of 80 mutations in the BRCA1 breast and ovarian cancer susceptibility gene. JAMA 273:535-541.
53. Shibata D (1994) Extraction of DNA from paraffin-embedded tissue for analysis by polymerase chain reaction: New tricks from an old friend. Hum Pathol 25:561-563.
54. Simard J, Feunteun J, Lenoir G, Tonin P, Normand T, The VL, Vivier A, Lasko D, Morgan K, Rouleau G, Lynch H, Labrie F, Narod S (1993) Genetic mapping of the breast-ovarian cancer syndrome to a small interval on chromosome 17q12-21; exclusion of candidate genes EDH17B2 and RARA. Hum Mol Genet 2:1193-1199.
55. Thompson ME, Jensen RA, Obermiller PS, Page DL, Holt JT (1995) Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression. Nat Genet 9:444-450.
56. Thorlacius S, Borresen AL, Eyfjörd JE (1993) Somatic p53 mutations in human breast carcinomas in an Iceland population: A prognostic factor. Cancer Res 53:1637-1641.
57. Wales MM, Biel MA, el Deiry W, Nelkin BD, Issa JP, Cavenee WK, Kuerbiu SJ, Baylin SB (1995) p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med 1:570-577.
58. Weinberg RA (1991) Tumor suppressor genes. Science 254:1138-1146.
59. Wooster R, Neuhausen SL, Mangion J, Quirk Y, Ford D, Collins N, Nguyen K, Seal S, Tran T, Averill D, Fields P, Marshall G, Narod S, Lenoir GM, Lynch H, Feunteun J, Devilee P, Cornelisse CJ, Menko FH, Daly PA, Ormiston W, McManus R, Pye C, Lewis CM, Cannon-Albright LA, Peto J, Ponder BAJ, Skolnick MH, Easton DF, Goldgar DE, Stratton MR (1994) Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13. Science 265:2088-2090.
60. Wooster R, Bignell G, Lancaster J, Swift S, Seal S, Mangion J, Collins N, Gregory S, Gumbs C, Micklem G, Barfoot R, Hamoudi R, Pantel S, Rice C, Biggs P, Hashim Y, Smith A, Connor F, Arason A, Gudmundsson J, Ficenec D, Kelsell D, Ford D, Tonin P, Bishop DT, Spurr NK, Ponder BAJ, Eeles R, Peto J, Devilee P, Cornelisse C, Lynch H, Narod S, Lenoir G, Egilsson V, Barkadottir RB, Easron DF, Bentley DR, Futreal PA, Ashworth A, Stratton MR (1995) Identification of the breast cancer gene BRCA2. Nature 378:789-792.
61. Zenklusen JC, Bièche I, Lidereau R, Conti CJ (1994) (C-A)n microsatellite repeat D7s522 is the most commonly deleted region in human primary breast cancer. Proc Natl Acad Sci USA 91:12155-12158.