Genomic deletion and p53 inactivation in cervical carcinoma

International Journal of Cancer

Volumn 72, Issue 2, 1997, Pages 270-276

  Ku, Wen Hui ^a   Liu, I Ling ^a   Yen, Ming Shyen ^b   Chang Chien, Chan Chou ^c   Yue, Chung Tai ^d   Ma, Yen Ying ^c   Chang, Shu Fen ^a   Ng, Heung Tat ^b   Wu, Cheng Wen ^a   Shen, Chen Yang ^a  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^d TAIWAN ADVENTIST HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53;

ARTICLE; CARCINOGENESIS; CHROMOSOME 3P; CHROMOSOME 5P; CHROMOSOME MAP; DNA DAMAGE; FEMALE; GENE DELETION; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TUMOR SUPPRESSOR GENE; UTERINE CERVIX CARCINOMA; WART VIRUS;

ADULT; AGED; CARCINOMA; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 3; CHROMOSOMES, HUMAN, PAIR 5; FEMALE; GENE DELETION; GENOME, HUMAN; HUMANS; MIDDLE AGED; TUMOR SUPPRESSOR PROTEIN P53; UTERINE CERVICAL NEOPLASMS;

EID: 0030745946     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970717)72:2<270::AID-IJC12>3.0.CO;2-K     Document Type: Article

References (44)

1. ALBERTS, B., BRAY, D., LEWIS, J., RAFF, M., ROBERTS, K. and WATSON, J.D., Molecular biology of the cell, pp. 1255-1294, Garland, New York (1994).
2. BERNARD, H.U., CHAN, S.Y., MANOS, M.M., ONG, C.K., VILLA, L.L., DELIUS, H., PEYTON, C.L., BAUER, H.M. and WHEELER, C.M., Identification and assessment of known and novel human papillomaviruses by polymerase chain reaction amplification, restriction fragment length polymorphisms, nucleotide sequence, and phylogenetic algorithms. J. infect. Dis., 170, 1077-1085 (1994).
3. BOSCH, F.X., MANOS, M.M., MUÑOZ, N., SHERMAN, M., JANSEN, A.M., PETO, J., SCHIFFMAN, M.H., MORENO, V., KURMAN, R. and SHAH, K.V., International Biological Study on Cervical Cancer Study Group. Prevalence of human papillomavirus in cervical cancer: a worldwide perspective. J. nat. Cancer Inst., 87, 796-802 (1995).
4. BRAUN, L., DURST, M., MIKUMO, R., CROWLEY, A. and ROBINSON, M., Regulation of growth and gene expression in human papillomavirus-transformed keratinocytes by transforming growth factor-beta: implications for the control of papillomavirus infection. Mol. Carcinogenesis, 6, 100-111 (1992).
5. CROOK, T. and VOUSDEN, K.H., Properties of p53 mutations detected in primary and secondary cervical cancers suggest mechanisms of metastasis and involvement of environmental carcinogens. EMBO J., 11, 3935-3940 (1992).
6. 1 arrest and apoptosis. Cancer Res., 54, 1169-1174 (1994).
7. FAKHARZADEH, S.S., TRUSKO, S.P. and GEORGE, D.L., Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J., 10, 1565-1569 (1991).
8. GREENBLATT, M.S., BENNETT, W.P., HOLLSTEIN, M. and HARRIS, C.C., Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res., 54, 4855-4878 (1994).
9. GUMBINER, B.M., Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell, 84, 345-357 (1996).
10. GYAPAY, G., MORISSETTE, J., VIGNAL, A., DIB, C., FIZAMES, C., MILLASSEAU, P., MARC, S., BERNARDI, G., LATHROP, M. and WEISSENBACK, J., The 1993-94 Généthon human genetic linkage map. Nature (Genet.), 7, 246-339 (1994).
11. HARTWELL, L.H., Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells. Cell, 71, 543-546 (1992).
12. HARTWELL, L.H. and KASTAN, M.B., Cell cycle control and cancer. Science, 266, 1821-1828 (1994).
13. HOLLSTEIN, M., SIDRANSKY, D., VOGELSTEIN, B. and HARRIS, C.C., p53 mutations in human cancers. Science, 253, 49-53 (1991).
14. KARLSEN, F., RABBITTS, P.H., SUNDRESAN, V. and HAGMAR, B., PCR-RFLP studies on chromosome 3p in formaldehyde-fixed, paraffin-embedded cervical cancer tissues. Int. J. Cancer, 58, 787-792 (1994).
15. KASTAN, M.B., ZHAN, Q., EL-DEIRY, W.S., CARRIER, F., JACKS, T., WALSH, W.V., PLUNKETT, B.S., VOGELSTKIN, B. and FORNACE, A.J., JR., A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is detective in ataxia-telangiectasis. Cell, 71, 587-597 (1992).
16. KESSIS, T.D., SLEBOS, R.J., HAN, S.M., SHAH, K., BOSCH, X.F., MUÑOZ, N., HEFRICK, L. and CHO, K.R., p53 gene mutation and MDM2 amplification are uncommon in primary carcinomas of the uterine cervix. Amer. J. Pathol., 143, 1398-1405 (1993a).
17. KESSIS, T.D., SLEBOS, R.J., NELSON, W.G., KASTAN, M.B., PLUNKETT, B.S., HAN, S.M., LORINCZ, A.T., HEDRICK, L. and CHO, K.R., HPV 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. nat. Acad. Sci. (Wash.), 90, 3988-3992 (1993b).
18. KOHNO, T., TAKAYAMA, H., HAMAGUCHI, M., TAKANO, H., YAMAGUCHI, N., TSUDA, H., HIROHASHI, S., VISSING, H., SHIMIZU, M., OSHIMURA, M. and YOKOTA, J., Deletion mapping of chromosome 3p in human uterine cervical cancer. Oncogene, 8, 1825-1832 (1993).
19. KUERBITZ, S.J., PLUNKETT, B.S., WALSH, W.V. and KASTAN, M.B., Wide-type p53 is a cell cycle checkpoint determinant following irradiation. Proc. nat. Acad. Sci. (Wash.), 89, 7491-7495 (1992).
20. LECHNER, M.S. and LAIMINS, L.A., Inhibition of p53 DNA binding by human papillomavirus E6 proteins. J. Virol., 68, 4262-4273 (1994).
21. LOEB, L.A., Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res., 54, 5059-5063 (1994).
22. LOU, M.A., TSENG, S.L., CHANG, S.F., YUE, C.T., CHANG, B.L., CHOU, C.H., YANG, S.L., TEH, B.H., WU, C.W. and SHEN, C.Y., Novel patterns of p53 abnormality in breast cancer from Taiwan: experience from a low incidence area. Brit. J. Cancer, 75, 746-751 (1997).
23. MANTEL, N. and HAENSZEL, W., Statistical aspects of the analysis of data from retrospective studies of disease. J. nat. Cancer Inst., 22, 719-748 (1959).
24. MARKOWITZ, S., WANG, J., MYEROFF, L., PARSONS, R., SUN, L., LUTTER-BAUGH, J., FAN, R.S., ZBOROWSKY, E., KINZLER, K.W., VOGELSTEIN, B., BRATTAIN, M. and WILLSON, K.V., Inactivation of the type II TGF-β receptor in colon cancer cells with microsatellite instability. Science, 268, 1336-1338 (1995).
25. MERLO, A., MABRY, M., GABRIELSON, E., VOLLMER, R., BAYLIN, S.B. and SIDRANSKY, D., Frequent microsatellite instability in primary small cell lung cancer. Cancer Res., 54, 2098-2101 (1994).
26. MITRA, A.B., MURTY, V.V.V.S., LI, R.G., PRATAP, M., LUTHRA, U.K. and CHAGANTI, R.S.K., Allelotype analysis of cervical carcinoma. Cancer Res., 54, 4481-4487 (1994).
27. MITRA, A.B., MURTY, V.V.V.S., SINGH, V., LI, R.G., PRATAP, M., SODHANI, P., LUTHRA, U.K. and CHAGANTI, R.S.K., Genetic alterations at 5p15: a potential marker for progression of precancerous lesions of the uterine cervix. J. nat. Cancer Inst., 87, 742-745 (1995).
28. MULLOKANDOV, M.R., KHOLODILOV, N.G., ATKIN, N.B., BURK, R.D., JOHNSON, A.B. and KLINGER, H.P., Genomic alterations in cervical carcinoma: losses of chromosome heterozygosity and human papilloma virus tumor status. Cancer Res., 56, 197-205 (1996).
29. NIGRA, J.M., BAKER, S.J., PREISINGER, A.C., JESSUP, J.M., HOSTETTER, R., CLEARY, K., BIGNER, S.H., DAVIDSON, N., BAYLIN, S., DEVILEE, P. and HARRIS, C.C., Mutations in the p53 gene occur in diverse human tumor types. Nature (Lond.), 342, 705-708 (1989).
30. OHTA, M., INOUE, H., COTTICELLI, M.G., KASTURY, K., BAFFA, R., PALAZZO, J., SIPRASHVILI, Z., MORI, M., MCCUE, P., DRUCK, T., CROCE, C.M. and HUEBNER, K., The human FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated translocation breakpoint, is abnormal in digestive tract cancers. Cell, 84, 587-597 (1996).
31. ORITA, M., IWAHANA, H., KANAZAWA, H., HAYASHI, K. and SEKIYA, T., Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. not. Acad. Sci. (Wash.), 86, 2766-2770 (1989).
32. PAPADOPOULOUS, N. and 19 OTHERS, Mutation of a mutL homolog in hereditary colon cancer. Science, 263, 1625-1629 (1994).
33. + tumor cells. Cell, 75, 1227-1236 (1993).
34. RODRIGUEZ, E., SREEKANTAIAH, C. and CHAGANTI, R.S.K., Genetic changes in epithelial solid neoplasia. Cancer Res., 54, 3398-3406 (1994).
35. SCHEFFNER, M., WERNESS, B.A., HUIBREGTSE, J.M., LEVINE, A.J. and HOWLEY, P.M., The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell, 63, 1129-1136 (1990).
36. SHAH, K.V. and HOWLEY, P.M., Papillomaviruses. In: B.N. Fields, D.M. Knipe and P.M. Howley (eds), Fields virology (3rd ed.), pp. 2077-2109, Lippincott-Raven, Philadelphia (1996).
37. SOZZI, G. and 13 OTHERS, The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell, 85, 17-26 (1996).
38. SU, L.K., VOGELSTEIN, B. and KINZLER, K.W., Association of the APC tumor suppressor protein with catenins. Science, 262, 1734-1737 (1993).
39. VOGELSTEIN, B. and KINZLER, K.W., p53 function and dysfunction. Cell, 70, 523-526 (1992).
40. VOUSDEN, K.H., Regulation of the cell cycle by viral oncoproteins. Semin. Cancer. Biol., 6, 109-116 (1995).
41. WILKE, C.M., HALL, B.K., HOGE, A., PARADEE, W., SMITH, D.I. and GLOVER, T.W., FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites. Human mol. Genet., 5, 187-195 (1996).
42. WRIGHT, T.C., FERENCZY, A. and KURMAN, R.J., Carcinoma and other tumors of the cervix. In: R.J. Kurman (ed.), Blaustein's pathology of the female genital tract, pp. 279-326, Springer-Verlag, New York (1994).
43. YIN, Y., TAINSKY, M.A., BISCHOFF, F.Z., STRONG, L.C. and WAHL, G.M., Wide-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles. Cell, 70, 937-948 (1992).
44. ZUR HAUSEN, H., Papillomaviruses in anogenital cancer as a model to understand the role of viruses in human cancers. Cancer Res., 49, 4677-4681 (1989).