-
1
-
-
0024329881
-
The biochemistry of P-glycoprotein-mediated multidrug resistance
-
Endicott, J.A. and Ling, V. (1989) The biochemistry of P-glycoprotein-mediated multidrug resistance. Annu. Rev. Biochem. 58, 137-171
-
(1989)
Annu. Rev. Biochem.
, vol.58
, pp. 137-171
-
-
Endicott, J.A.1
Ling, V.2
-
2
-
-
0024424270
-
Identification of the cystic fibrosis gene: Cloning and characterisation of complentary DNA
-
Riordan, J.R. et al. (1989) Identification of the cystic fibrosis gene: cloning and characterisation of complentary DNA. Science 245, 1066-1073
-
(1989)
Science
, vol.245
, pp. 1066-1073
-
-
Riordan, J.R.1
-
3
-
-
0021717782
-
ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system
-
Hobson, A.C., Weathermax, R. and Ames, G.F.L. (1984) ATP-binding sites in the membrane components of histidine permease, a periplasmic transport system. Proc. Natl Acad. Sci. USA 81, 7333-7337
-
(1984)
Proc. Natl Acad. Sci. USA
, vol.81
, pp. 7333-7337
-
-
Hobson, A.C.1
Weathermax, R.2
Ames, G.F.L.3
-
4
-
-
0025203678
-
The nucleotide binding site of hisP, a membrane protein of the histidine permease: Identification of amino acid residues photoaffinity labeled by 8-azido-ATP
-
Mimura, C.S. et al. (1990) The nucleotide binding site of hisP, a membrane protein of the histidine permease: identification of amino acid residues photoaffinity labeled by 8-azido-ATP. J. Biol. Chem. 256, 19535-19542
-
(1990)
J. Biol. Chem.
, vol.256
, pp. 19535-19542
-
-
Mimura, C.S.1
-
5
-
-
0023666563
-
Efflux of chloroquine from Plasmodium falcipanim: Mechanism of chloroquine resistance
-
Krogstad, D.J. et al. (1987) Efflux of chloroquine from Plasmodium falcipanim: mechanism of chloroquine resistance. Science 238, 1283-1285
-
(1987)
Science
, vol.238
, pp. 1283-1285
-
-
Krogstad, D.J.1
-
6
-
-
0023137728
-
Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
-
Martin, S.K., Oduola, A.M. and Milhous, W.K. (1987) Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science 235, 899-901
-
(1987)
Science
, vol.235
, pp. 899-901
-
-
Martin, S.K.1
Oduola, A.M.2
Milhous, W.K.3
-
7
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
-
Foote, S.J. et al. (1989) Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57, 921-930
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
-
8
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug-resistant falciparum malaria
-
Wilson, C.M. et al. (1989) Amplification of a gene related to mammalian mdr genes in drug-resistant falciparum malaria. Science 244, 1184-1186
-
(1989)
Science
, vol.244
, pp. 1184-1186
-
-
Wilson, C.M.1
-
9
-
-
0027442477
-
Characterization of the pfmdr2 gene for Plasmodium falciparum
-
Zalis, MG. et al. (1993) Characterization of the pfmdr2 gene for Plasmodium falciparum. Mol. Biochem. Parasitol. 62, 83-92
-
(1993)
Mol. Biochem. Parasitol.
, vol.62
, pp. 83-92
-
-
Zalis, M.G.1
-
10
-
-
0028169583
-
Plasmodium falciparum: The pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of the malaria parasite
-
Rubio, J.P. and Cowman, A.F. (1994) Plasmodium falciparum: the pfmdr2 protein is not overexpressed in chloroquine-resistant isolates of the malaria parasite. Exp. Parasitol. 79, 137-147
-
(1994)
Exp. Parasitol.
, vol.79
, pp. 137-147
-
-
Rubio, J.P.1
Cowman, A.F.2
-
11
-
-
0025786518
-
A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole
-
Cowman, A.F. et al. (1991) A P-glycoprotein homologue of Plasmodium falciparum is localized on the digestive vacuole. J. Cell Biol. 113, 1033-1042
-
(1991)
J. Cell Biol.
, vol.113
, pp. 1033-1042
-
-
Cowman, A.F.1
-
12
-
-
0027406890
-
Nucleotide binding properties of a P-glycoprotein homologue from Plasmodium falciparum
-
Karcz, S.R., Galatis, D. and Cowman, A.F. (1993) Nucleotide binding properties of a P-glycoprotein homologue from Plasmodium falciparum. Mol. Biochem. Parasitol. 58, 269-276
-
(1993)
Mol. Biochem. Parasitol.
, vol.58
, pp. 269-276
-
-
Karcz, S.R.1
Galatis, D.2
Cowman, A.F.3
-
13
-
-
0027732045
-
Phosphorylation of a P-glycoprotein homologue in Plasmodium falciparum
-
Lim, A.S.Y. and Cowman, A.F. (1993) Phosphorylation of a P-glycoprotein homologue in Plasmodium falciparum. Mol. Biochem. Parasitol. 62, 293-302
-
(1993)
Mol. Biochem. Parasitol.
, vol.62
, pp. 293-302
-
-
Lim, A.S.Y.1
Cowman, A.F.2
-
14
-
-
0025305350
-
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross
-
Wellems, T.E. et al. (1990) Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross. Nature 345, 253-255
-
(1990)
Nature
, vol.345
, pp. 253-255
-
-
Wellems, T.E.1
-
15
-
-
0026328231
-
Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7
-
Wellems, T.E., Walker, J.A. and Panton, L.J. (1991) Genetic mapping of the chloroquine-resistance locus on Plasmodium falciparum chromosome 7. Proc. Natl Acad. Sci. USA 88, 3382-3386
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, pp. 3382-3386
-
-
Wellems, T.E.1
Walker, J.A.2
Panton, L.J.3
-
16
-
-
0025269612
-
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum
-
Foote, S.J. et al. (1990) Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature 345, 255-258
-
(1990)
Nature
, vol.345
, pp. 255-258
-
-
Foote, S.J.1
-
17
-
-
0027339057
-
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
-
Wilson, C.M. et al. (1993) Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol. Biochem. Parasitol. 57, 151-160
-
(1993)
Mol. Biochem. Parasitol.
, vol.57
, pp. 151-160
-
-
Wilson, C.M.1
-
18
-
-
85030189342
-
Analysis of pfmdrl and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa
-
in press
-
Basco, L.K. et al. Analysis of pfmdrl and drug susceptibility in fresh isolates of Plasmodium falciparum from Subsaharan Africa. Mol. Biochem. Parasitol. (in press)
-
Mol. Biochem. Parasitol.
-
-
Basco, L.K.1
-
19
-
-
0001605080
-
Pfmdrl mutations and chloroquine-resistance in Plasmodium falciparum isolates from Zaira, Nigeria
-
Adagu, I.S. et al. (1985) Pfmdrl mutations and chloroquine-resistance in Plasmodium falciparum isolates from Zaira, Nigeria. Trans. R. Soc. Trop. Med. Hyg. 89, 132
-
(1985)
Trans. R. Soc. Trop. Med. Hyg.
, vol.89
, pp. 132
-
-
Adagu, I.S.1
-
20
-
-
0028274565
-
Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine
-
Van Es, H.H.G. et al. (1994) Expression of the plasmodial pfmdr1 gene in mammalian cells is associated with increased susceptibility to chloroquine. Mol. Cell. Biol. 14, 2419-2428
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2419-2428
-
-
Van Es, H.H.G.1
-
21
-
-
0009570521
-
Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum
-
Volkman, S.K., Cowman, A.F. and Wirth, D.F. (1996) Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum. Proc. Natl Acad. Sci. USA 93, 3479-3491
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 3479-3491
-
-
Volkman, S.K.1
Cowman, A.F.2
Wirth, D.F.3
-
22
-
-
0028607543
-
Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdrl gene
-
Van Es, H.H.G. et al. (1994) Enhanced lysosomal acidification leads to increased chloroquine accumulation in CHO cells expressing the pfmdrl gene. Mol. Biochem. Parasitol. 68, 209-219
-
(1994)
Mol. Biochem. Parasitol.
, vol.68
, pp. 209-219
-
-
Van Es, H.H.G.1
-
23
-
-
0028334009
-
Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falicparum
-
Foley, M. et al. (1994) Photoaffinity labeling of chloroquine-binding proteins in Plasmodium falicparum. J. Biol. Chem. 269, 6955-6961
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6955-6961
-
-
Foley, M.1
-
24
-
-
0024389333
-
Structure and function of vacuolar class of ATP-driven proton pumps
-
Forgac, M. (1989) Structure and function of vacuolar class of ATP-driven proton pumps. Physiol. Res. 69, 765-796
-
(1989)
Physiol. Res.
, vol.69
, pp. 765-796
-
-
Forgac, M.1
-
25
-
-
0025784535
-
Defective acidification of intracellular organelles in cystic fibrosis
-
Barasch, J. et al. (1991) Defective acidification of intracellular organelles in cystic fibrosis. Nature 352, 70-73
-
(1991)
Nature
, vol.352
, pp. 70-73
-
-
Barasch, J.1
-
26
-
-
0026775053
-
Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein
-
Gill, D.R. et al. (1992) Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell 71, 23-32
-
(1992)
Cell
, vol.71
, pp. 23-32
-
-
Gill, D.R.1
-
27
-
-
0026536805
-
Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein
-
Valverde, M.A., Diaz, M. and Sepulveda, F.V. (1992) Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature 355, 830-833
-
(1992)
Nature
, vol.355
, pp. 830-833
-
-
Valverde, M.A.1
Diaz, M.2
Sepulveda, F.V.3
-
28
-
-
0027452387
-
Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: Further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein
-
Roepe, P.D. et al. (1993) Lower electrical membrane potential and altered pHi homeostasis in multidrug-resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein. Biochemistry 32, 11042-11056
-
(1993)
Biochemistry
, vol.32
, pp. 11042-11056
-
-
Roepe, P.D.1
-
29
-
-
0028128073
-
Intracellular pH and the control of multidrug resistance
-
Simon, S., Roy, D. and Schindler, M. (1994) Intracellular pH and the control of multidrug resistance. Proc. Natl Acad. Sci. US A 91, 1128-1132
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 1128-1132
-
-
Simon, S.1
Roy, D.2
Schindler, M.3
-
30
-
-
0028307529
-
3 exchange in Chinese hamster ovary cells
-
3 exchange in Chinese hamster ovary cells. Biochemistry 33, 7239-7249
-
(1994)
Biochemistry
, vol.33
, pp. 7239-7249
-
-
Luz, J.G.1
-
31
-
-
0024375860
-
The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein
-
McGrath, J.P. and Varshavsky, A. (1989) The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature 240, 400-404
-
(1989)
Nature
, vol.240
, pp. 400-404
-
-
McGrath, J.P.1
Varshavsky, A.2
-
32
-
-
0026645269
-
Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum
-
Barnes, D.A. et al. (1992) Selection for high-level chloroquine resistance results in deamplification of the pfmdr1 gene and increased sensitivity to mefloquine in Plasmodium falciparum. EMBO J. 11, 3067-3075
-
(1992)
EMBO J.
, vol.11
, pp. 3067-3075
-
-
Barnes, D.A.1
-
33
-
-
0026048108
-
Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events
-
Triglia, T. et al. (1991) Amplification of the multidrug resistance gene pfmdr1 in Plasmodium falciparum has arisen as multiple independent events. Mol. Cell. Biol. 11, 5244-5250
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5244-5250
-
-
Triglia, T.1
-
34
-
-
0028135205
-
A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and muttion in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro
-
Peel, S.A. et al. (1994) A strong association between mefloquine and halofantrine resistance and amplification, overexpression, and muttion in the P-glycoprotein gene homolog (pfmdr) of Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 51, 648-658
-
(1994)
Am. J. Trop. Med. Hyg.
, vol.51
, pp. 648-658
-
-
Peel, S.A.1
-
35
-
-
0028014644
-
Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine
-
Cowman, A.F., Galatis, D. and Thompson, J.K. (1994) Selection for mefloquine resistance in Plasmodium falciparum is linked to amplification of the pfmdr1 gene and cross-resistance to halofantrine and quinine. Proc. Natl Acad. Sci. USA 91, 1143-1147
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 1143-1147
-
-
Cowman, A.F.1
Galatis, D.2
Thompson, J.K.3
-
36
-
-
0027474443
-
Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro
-
Peel, S.A. et al. (1993) Derivation of highly mefloquine-resistant lines from Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg. 48, 385-397
-
(1993)
Am. J. Trop. Med. Hyg.
, vol.48
, pp. 385-397
-
-
Peel, S.A.1
-
37
-
-
0026581070
-
Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. I. Stable figures of prevalence of chloroquine- and quinine-resistant isolates in the original foci
-
Brasseur, P. et al. (1992) Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. I. Stable figures of prevalence of chloroquine- and quinine-resistant isolates in the original foci. Am. J. Trop. Med. Hyg. 46, 1-7
-
(1992)
Am. J. Trop. Med. Hyg.
, vol.46
, pp. 1-7
-
-
Brasseur, P.1
-
38
-
-
0026562874
-
Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. II. Mefloquine resistance confirmed in vivo and in vitro and its correlation with quinine resistance
-
Brasseur, P. et al. (1992) Multi-drug resistant falciparum malaria in Cameroon in 1987-1988. II. Mefloquine resistance confirmed in vivo and in vitro and its correlation with quinine resistance. Am. J. Trop. Med. Hyg. 46, 8-14
-
(1992)
Am. J. Trop. Med. Hyg.
, vol.46
, pp. 8-14
-
-
Brasseur, P.1
-
39
-
-
0022993652
-
Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins
-
Gros, P., Croop, J. and Housman, D. (1986) Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteins. Cell 47, 371-380
-
(1986)
Cell
, vol.47
, pp. 371-380
-
-
Gros, P.1
Croop, J.2
Housman, D.3
-
40
-
-
0026660329
-
Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter
-
Ortiz, D. F. et al (1992) Heavy metal tolerance in the fission yeast requires an ATP-binding cassette-type vacuolar membrane transporter. EMBO J. 11, 3491-3499
-
(1992)
EMBO J.
, vol.11
, pp. 3491-3499
-
-
Ortiz, D.F.1
-
41
-
-
0027215242
-
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site
-
Kajiji, S. et al. (1993) Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site. Biochemistry 32, 4185-4194
-
(1993)
Biochemistry
, vol.32
, pp. 4185-4194
-
-
Kajiji, S.1
-
42
-
-
0026272262
-
The pfmdr gene homologues of Plasmodium falciparum
-
Cowman, A.F. and Karcz, S. (1991) The pfmdr gene homologues of Plasmodium falciparum. Acta Liedensia 60, 121-129
-
(1991)
Acta Liedensia
, vol.60
, pp. 121-129
-
-
Cowman, A.F.1
Karcz, S.2
-
43
-
-
0027473406
-
Transcripts of the multidrug resistance genes in chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum
-
Ekong, R.M. et al. (1993) Transcripts of the multidrug resistance genes in chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. Parasitology 106, 107-115
-
(1993)
Parasitology
, vol.106
, pp. 107-115
-
-
Ekong, R.M.1
-
44
-
-
0026028916
-
The P-glycoprotein homologues of Plasmodium falciparum: Are they involved in chloroquine resistance?
-
Cowman, A.F. (1991) The P-glycoprotein homologues of Plasmodium falciparum: are they involved in chloroquine resistance? Parasitology Today 7, 70-76
-
(1991)
Parasitology Today
, vol.7
, pp. 70-76
-
-
Cowman, A.F.1
|