Daughters against dpp modulates dpp organizing activity in Drosophila wing development

Nature

Volumn 389, Issue 6651, 1997, Pages 627-631

  Tsuneizumi, Kazuhide ^a   Nakayama, Takuya ^b   Kamoshida, Yuko ^a   Kornberg, Thomas B ^c   Christian, Jan L ^b   Tabata, Tetsuya ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; DECAPENTAPLEGIC PROTEIN; MORPHOGEN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; EMBRYO; EMBRYO PATTERN FORMATION; FORELIMB; GENE EXPRESSION; NEGATIVE FEEDBACK; NONHUMAN; OOCYTE; PRIORITY JOURNAL; XENOPUS;

AMINO ACID SEQUENCE; ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; CLONING, MOLECULAR; DNA-BINDING PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; INSECT PROTEINS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NERVE TISSUE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; WING; XENOPUS; XENOPUS PROTEINS;

ANIMALIA; VERTEBRATA;

EID: 0030863365     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/39362     Document Type: Article

References (32)

1. Hogan, B. L. M. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev. 10, 1580-1594 (1996).
2. Padgett, R. W., St Johnston, R. D. & Gelbart, W. M. A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-β family. Nature 325, 81-84 (1987).
3. Ferguson, L. F. & Anderson, K. V. Decapentaplegic acts as a morphogen to Organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461 (1992).
4. Lecuiti T. et al. Two distinct mechanisms for long-range patterning by Decapentaplegic in the Drosophila wing. Nature 381, 387-393 (1996).
5. Nellen, D., Burke, R., Struhl, G. & Basler, K. Direct and long-range action of a DPP morphogen gradient. Cell 85, 357-368 (1996).
6. Sekelsky, J., Newfeld, S., Raftery, L., Chartoff, E. & Gelhart, W. Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358 (1995).
7. Ferguson, E. L. Conservation of dorsal-ventral patterning in arthropods and chordates. Curr. Opin. Genet. Dev. 6, 424-431 (1996).
8. Zecca, M., Basler, K. & Struhl, G. Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing. Development 121, 2265-2278 (1995).
9. Tabata, T., Schwartz, C., Gustavson, E., Ali, Z. & Kornberg, T. B. Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis. Development 121, 3359-3369 (1995).
10. Lawrence, P. A. & Struhl, G. Morphogens, compartments, and pattern: lessons from Drosophila? Cell 85, 951-961 (1996).
11. Capdevila, J. & Guerrero, I. Targeted expression of the signaling molecule decepentaplegic induces pattern duplications and growth alterations in Drosophila wings. EMBO J. 13, 4459-4468 (1994).
12. Brand, A. H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).
13. Savage, C. et al. Caenorhabditis elegans genes sma-2, sma-3 and sma-4 define a conserved family of transforming growth factor-β pathway components, Proc. Natl Acad. Sci. USA 93, 790-794 (1996).
14. Massague, J., Hata, A. & Fang, L. TGF-β signaling through the Smad pathway. Trends Cell Biol. 7, 187-192 (1997).
15. Riggins, G. J. et al. Mad-related genes in the human. Nature Genet 13, 347-349 (1996).
16. Burke, R. & Basler, K. Dpp receptors arc autonomously required for cell proliferation in the entire developing Drosophila wing. Development 122, 2261-2269 (1996).
17. Grimnn, S. & Pflugfelder, G. O. Control of the gene optomotor-blind in Drosophila wing development by decapentaplegic and wingless. Science 271, 1601-1604 (1996).
18. Kao, K. R. & Elinson, R. P. Dorsalization of mesoderm induction by lithium. Dev. Biol. 132, 81-90 (1989).
19. Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massage, J. Partnership between DPC4 and SMAD in TGF-β-signalling pathways. Nature 383, 832-836 (1996).
20. Macias-Silva, M. et al. MADR2 is a substrate of the TGFβ receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215-1224 (1997).
21. Hayashi, H. et al. The Mad-related protein Smad7 associates with the TGFβ receptor and functions as an antagonist of TGFβ signaling. Cell 89, 1165-1173 (1997).
22. Newfeld, S. J., Chartoff, E. H., Graff, J. M., Melton, D. A. & Gelbart, W. M. Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-β responsive cells. Development 122, 2099-2108 (1996).
23. Ito, K., Awano, W., Suzuki, K., Hiromi, Y. & Yamamoto, D. The Drosophila mushroom body is a quadruple structure of clonal units each of which contains a virtually identical set of neurones and glial cells. Development 124, 761-771 (1997).
24. Moon, R. T. & Christian, J. L. Microinjection and expression of synthetic mRNAs in Xenopus embryos. Technique 1, 76-89 (1989).
25. Cui, Y., Tian, Q. & Christian, J. L. Synergistic effects of Vg1 and Wnt signals in the specification of dorsal mesoderm and endoderm. Dev. Biol. 180, 22-34 (1996).
26. Kengaku, M. & Okamoto, H. bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus. Development 121, 3121-3130 (1995).
27. Hemmati-Brivanlou, A. & Melton, D. A. Inhibition of activin receptor signaling promotes neuraltzation in Xenopus. Cell 77, 273-281 (1994).
28. Lai, C.-J., Ekker, S. C., Beachy, P. A. & Moon, R. T. Patterning of the neural ectoderm of Xenopus laevis by the amino-terminal product of hedgehog autoproteolytic cleavage. Development 121, 2349-2360 (1995).
29. Blitz, I. L. & Cho, K. W. Y. Anterior neurectoderm is progressively induced during gastrulation: the role of the Xenopus homeobox gene arthodenticle. Development 121, 993-1004 (1995).
30. Hemmati-Brivanlou, A., Kelly, O. G. & Melton, D. A. Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295 (1994).
31. Tabata, T. & Kornberg, T. B. Hedgehog is a signalling protein with a key role in patterning in Drosophila. Cell 76, 89-102 (1994).
32. Liu, F. et al. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623 (1996).