-
1
-
-
0023924549
-
In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulfonamides and quinolines
-
Back, D.J., Tjia, J.F., Karbwang, J. and Colbert, J. (1988): In vitro inhibition studies of tolbutamide hydroxylase activity of human liver microsomes by azoles, sulfonamides and quinolines. Br. J. Clin. Pharmacol., 26, 23-29.
-
(1988)
Br. J. Clin. Pharmacol.
, vol.26
, pp. 23-29
-
-
Back, D.J.1
Tjia, J.F.2
Karbwang, J.3
Colbert, J.4
-
2
-
-
0002570237
-
Sulphaphenazole-induced hypoglycaemic attacks in tolbutamide-treated diabetics
-
Christensen, L.K, Hansen, J.M. and Kristensen, M. (1963): Sulphaphenazole-induced hypoglycaemic attacks in tolbutamide-treated diabetics. Lancet, 2, 1298-1301.
-
(1963)
Lancet
, vol.2
, pp. 1298-1301
-
-
Christensen, L.K.1
Hansen, J.M.2
Kristensen, M.3
-
3
-
-
0029057852
-
Prediction of the maximal tolerated dose (MTD) and therapeutic effect of anticancer drugs in humans: Integration of pharmacokinetics with pharmacodynamics and toxicodynamics
-
Fuse, E., Kobayashi, T., Inaba, M. and Sugiyama, Y. (1995): Prediction of the maximal tolerated dose (MTD) and therapeutic effect of anticancer drugs in humans: integration of pharmacokinetics with pharmacodynamics and toxicodynamics. Cancer Treatment Reviews, 21, 133-157.
-
(1995)
Cancer Treatment Reviews
, vol.21
, pp. 133-157
-
-
Fuse, E.1
Kobayashi, T.2
Inaba, M.3
Sugiyama, Y.4
-
4
-
-
0029950964
-
Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics
-
Iwatsubo, T., Hirota, N., Ooie, T., Suzuki, H. and Sugiyama, Y. (1996): Prediction of in vivo drug disposition from in vitro data based on physiological pharmacokinetics. Biopharm. Drug Disposit., 17, 273-310.
-
(1996)
Biopharm. Drug Disposit.
, vol.17
, pp. 273-310
-
-
Iwatsubo, T.1
Hirota, N.2
Ooie, T.3
Suzuki, H.4
Sugiyama, Y.5
-
5
-
-
84920293238
-
Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data
-
in press
-
Iwatsubo, T., Hirota, N., Ooie, T., Suzuki, H., Shimada, N., Chiba, K., Ishizaki, T., Green, C.E., Tyson, C.A. and Sugiyama, Y.: Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data. Pharmacol. Ther., in press.
-
Pharmacol. Ther.
-
-
Iwatsubo, T.1
Hirota, N.2
Ooie, T.3
Suzuki, H.4
Shimada, N.5
Chiba, K.6
Ishizaki, T.7
Green, C.E.8
Tyson, C.A.9
Sugiyama, Y.10
-
6
-
-
0023873591
-
Tolbutamide hydroxylation by human liver microsomes
-
Miners, J. O., Smith, K.J., Robson, R.A., McManus, M.E., Veronese, M.E. and Birkett, D.J. (1988): Tolbutamide hydroxylation by human liver microsomes. Biochem. Pharmacol., 37, 1137-1144.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 1137-1144
-
-
Miners, J.O.1
Smith, K.J.2
Robson, R.A.3
McManus, M.E.4
Veronese, M.E.5
Birkett, D.J.6
-
7
-
-
0007562143
-
Alteration of pharmacokinetic features caused by drug interactions
-
Sugiyama, Y. and Iwatsubo, T. (1996): Alteration of pharmacokinetic features caused by drug interactions. Xenobio. Metabol. and Dispos., 11, 286-293.
-
(1996)
Xenobio. Metabol. and Dispos.
, vol.11
, pp. 286-293
-
-
Sugiyama, Y.1
Iwatsubo, T.2
-
8
-
-
3142513216
-
Prediction of pharmacokinetics based on in vitro data
-
Methods and Techniques for Pharmacokinetic Studies (Sugiyama, Y., ed.), Tokyo
-
Sugiyama, Y. and Ooie, T. (1993): Prediction of pharmacokinetics based on in vitro data. In: Methods and Techniques for Pharmacokinetic Studies (Sugiyama, Y., ed.), pp. 87-108, Japanese Society for the Study of Xenobiotics, Tokyo.
-
(1993)
Japanese Society for the Study of Xenobiotics
, pp. 87-108
-
-
Sugiyama, Y.1
Ooie, T.2
-
9
-
-
0013926913
-
The metabolic fate of tolbutamide in man and in the rat
-
Thomas, R.C. and Ikeda, G.J. (1966): The metabolic fate of tolbutamide in man and in the rat. J. Med. Chem., 9, 507-510.
-
(1966)
J. Med. Chem.
, vol.9
, pp. 507-510
-
-
Thomas, R.C.1
Ikeda, G.J.2
-
10
-
-
0025264682
-
Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers
-
Veronese, M.E., Miners, J.O., Randles, D., Gregov, D. and Birkett, D.J. (1990): Validation of the tolbutamide metabolic ratio for population screening with use of sulfaphenazole to produce model phenotypic poor metabolizers. Clin. Pharmacol. Ther., 47, 403-411.
-
(1990)
Clin. Pharmacol. Ther.
, vol.47
, pp. 403-411
-
-
Veronese, M.E.1
Miners, J.O.2
Randles, D.3
Gregov, D.4
Birkett, D.J.5
-
11
-
-
0028820208
-
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
-
Wu, C.-Y., Benet, L.Z., Hebert, M.F., Gupta, S.K., Rowland, M., Gomez, D.Y. and Wacher, V.J. (1995): Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine. Clin. Pharmacol. Ther., 58, 492-497.
-
(1995)
Clin. Pharmacol. Ther.
, vol.58
, pp. 492-497
-
-
Wu, C.-Y.1
Benet, L.Z.2
Hebert, M.F.3
Gupta, S.K.4
Rowland, M.5
Gomez, D.Y.6
Wacher, V.J.7
-
12
-
-
85035188406
-
-
Yamazaki, M., Nishigaki, R., Suzuki, H. and Sugiyama, Y. (1995): Kinetic analysis of hepatobiliary transport of drugs: Importance of carrier-mediated transport.
-
(1995)
Kinetic Analysis of Hepatobiliary Transport of Drugs: Importance of Carrier-mediated Transport
-
-
Yamazaki, M.1
Nishigaki, R.2
Suzuki, H.3
Sugiyama, Y.4
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