Persistent expression of genes of the enhancer of split complex suppresses neural development in Drosophila

Neuron

Volumn 16, Issue 2, 1996, Pages 275-286

  Nakao, Keiko ^a   Campos Ortega, José A ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; DNA BINDING; DROSOPHILA; GENE EXPRESSION; NERVOUS SYSTEM DEVELOPMENT; NEUROBLAST; NONHUMAN; PRIORITY JOURNAL; STEM CELL;

EID: 0030050829     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80046-X     Document Type: Article

References (59)

1. Abrams, J.M., White, K., Fessler, L.I., and Steller, H. (1993). Programmed cell death during Drosophila embryogenesis. Development 117, 29-43.
2. Alberga, A., Boulay, J.L., Kempe, E., Dennefeld, C., and Haenlin, M. (1991). The snail gene required for mesodermal formation in Drosophila is expressed dynamically in derivatives of all three germ layers. Development 111, 983-992.
3. Bellen, H.J., O'Kane, C.J., Wilson, C., Grossniklaus, U., Pearson R.K., and Gehring, W.J. (1989). P-element-mediated enhancer detection: a versatile method to study development in Drosophila. Genes Dev. 3, 1288-1300.
4. Boulianne, G.L., de la Choncha, A., Campos-Ortega, J.A., Jan, L., and Jan, Y.N. (1991). The Drosophila neurogenic gene neuralized encodes a novel protein and is expressed in precursors of larval and adult neurons. EMBO J. 10, 2975-2983.
5. Brand, M., and Campos-Ortega, J.A. (1988). Two groups of interrelated genes regulate early neurogenesis in Drosophila melanogaster. Roux's Arch. Dev. Biol. 197, 457-470.
6. Brand, A.H., and Perrimon, N. (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotype. Development 118, 401-415.
7. Brand, M., Jarman, A., Jan, L.Y., and Jan, Y.N. (1993) asense is a Drosophila neural precursor gene and is capable of initiating sense organ formation. Development 119, 1-17.
8. Cabrera, C.V., Martinez-Arias, A., and Bate, M. (1987). The expression of three members of the achaete-scute gene complex correlates with neuroblast segregation in Drosophila. Cell 50, 425-433
9. Campos-Ortega, J.A. (1993). Early neurogenesis in Drosophila melanogaster. In Development of Drosophila, C.M. Bate, A. Martinez-Arias, eds. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
10. Campos-Ortega, J.A., and Haenlin, M. (1992). Regulatory signals and signal molecules in early neurogenesis of Drosophila melanogaster. Roux's Arch. Dev. Biol. 201, 1-11.
11. Campos-Ortega, J.A., and Hartenstein, V. (1985). The Embryonic Development of Drosophila melanogaster. (Berlin: Springer-Verlag).
12. Campuzano, S., and Modolell, J. (1992). Patterning of the Drosophila nervous system: the achaete-scute gene complex. Trends Genet. 8, 202-208.
13. Cronmiller, C., and Cummings, C.A. (1993). The daughterless gene product in Drosophila is a nuclear protein that is broadly expressed throughout the organism during development. Mech. Dev. 42, 159-169.
14. de la Concha, A., Dietrich, U., Weigel, D., and Campos-Ortega, J.A. (1988). Functional interactions of neurogenic genes of Drosophila melanogaster. Genetics 118, 499-508.
15. Dedidakis, C., and Artavanis-Tsakonas, S. (1992). The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins. Proc. Natl. Acad. Sci. USA 89, 8731-8735.
16. Doe, C.Q. (1992). Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system. Development 116, 855-863.
17. Fischer, J.A., Giniger, E., Maniatis, T., and Ptashne, M. (1988). GAL4 activate transcription in Drosophila. Nature 332, 853-856.
18. Ghysen, A., and Dambly-Chaudière, C. (1989). Genesis of the Drosophila peripheral nervous system. Trends Genet. 5 251-255.
19. Ghysen, A., Dambly-Chaudière, C., Jan, L.Y., and Jan, Y.-N. (1993). Cell interactions and gene interactions in peripheral neurogenesis. Genes Dev. 7, 723-733.
20. Hartenstein, V., and Campos-Ortega, J.A. (1984). Early neurogenesis in wild-type Drosophila melanogaster. Roux's Arch. Dev. Biol. 193, 308-325.
21. Hartenstein, V., Younossi-Hartenstein, A., and Lekven, A. (1994). Delamination and division in the Drosophila neuroectoderm: spatio-temporal pattern, cytoskeletal dynamics and common control by neurogenic and segment polarity genes. Dev. Biol. 165, 480-499.
22. Hinz, U., Giebel, B., and Campos-Ortega, J.A. (1994). The basic-helix-loop-helix domain of the Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes. Cell 76, 1-11.
23. Huang, F., Dambly-Chaudiere, C., and Ghysen A. (1991). The emergence of sense organs in the wing disc of Drosophila. Development 111, 1087-1095.
24. Ip, Y.T., Levine, M., and Bier, E. (1994). Neurogenic expression of snail is controlled by separable CNS and PNS promoter elements. Development 120, 199-207.
25. Jennings, B., Preiss, A., Delidakis, C., and Bray, S. (1994). The Notch signalling pathway is required for Enhancer of split bHLH protein expression during neurogenesis in the Drosophila embryo. Development 120, 3537-3548.
26. Jiménez, F., and Campos-Ortega, J.A. (1979). A region of the Drosophila genome necessary for CNS development. Nature 282, 310-312.
27. Jiménez, F., and Campos-Ortega, J.A. (1987). Genes in subdivision 1B of the Drosophila melanogaster X-chromosome and their influence on neural development. J. Neurogen. 4, 179-200.
28. Jiménez, F., and Campos-Ortega, J.A. (1990). Defective neuroblast commitment in mutants of the achaete-scute complex and adjacent genes of Drosophila melanogaster. Neuron 5, 81-89
29. Jiménez, F., Martin-Morris, L.E., Velasco, L., Chu, H., Sierra, J., Rosen, D.R., and White, K. (1995). vnd, a gene required for early neurogenesis of Drosophila, encodes a homeodomain protein. EMBO J. 14, 3487-3495.
30. Klämbt, C., Knust, E., Tietze, K., and Campos-Ortega, J.A. (1989). Closely related transcripts encoded by the neurogenic gene complex Enhancer of split of Drosophila melanogaster. EMBO J. 8, 203-210.
31. Knust, E., Tietze, K., and Campos-Ortega, J. A. (1987). Molecular analysis of the neurogenic locus Enhancer of split of Drosophila melanogaster. EMBO J. 6, 4113-4123.
32. Knust, E., Schrons, H., Grawe, F., and Campos-Ortega, J.A. (1992). Seven genes of the Enhancer of split complex of Drosophila melanogaster encode helix-loop-helix proteins. Genetics 132, 505-518.
33. Kramatschek, B., and Campos-Ortega, J.A. (1994). Neuroectodermal transcription of the Drosophila neurogenic genes E(spl) and HLH-m5 is regulated by proneural genes. Development 120, 815-826.
34. Lehmann, R., Dietrich, U., Jiménez, F., and Campos-Ortega, J.A. (1981). Mutations of early neurogenesis in Drosophila. Roux's Arch. Dev. Biol. 190, 226-229.
35. Lehmann, R., Jiménez, F., Dietrich, U., and Campos-Ortega, J.A. (1983). On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster. Roux's Arch. Dev. Biol. 192, 62-74.
36. Lieber, T., Kidd, S., Alcamo, E., Corbin, V., and Young, M.W. (1993). Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7, 1949-1965.
37. Mlodzik, M., Baker, N.E., and Rubin, G.M. (1991). Isolation and expression of scabrous, a gene regulating neurogenesis in Drosophila. Genes Dev. 4, 1848-1861.
38. Oellers, N., Dehio, M., and Knust, E. (1994). bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes. Mol. Gen. Genet. 244, 465-473.
39. Ohsako, S., Hyer, J., Panganiban, G., Oliver, I., and Caudy, M. (1994). hairy functions as a DNA-binding helix-loop-helix repressor of Drosophila sensory organ formation. Genes Dev. 8, 2743-2755.
40. Romani, S., Campuzano, S., Macagno, E.R., and Modolell, J. (1989). Expression of achaete and scute genes in Drosophila imaginai discs and their function in sensory organ development. Genes Dev. 3, 997-1007.
41. Ruiz-Gómez, M., and Ghysen, A. (1993). The expression and role of a proneural gene, achaete, in the development of the larval nervous system of Drosophila. EMBO J. 12, 1121-1130.
42. Schrons, H., Knust, E., and Campos-Ortega, J.A. (1992). The Enhancer of split complex and adjacent genes in the 96F region of Drosophila melanogaster are required for segregation of neural and epidermal progenitor cells. Genetics 132, 481-503.
43. Shepard, S.B., Broverman, S.A., and Muskavitch, M.A.T. (1989). A tripartite interaction among alleles of Notch, Delta and Enhancer of split during imaginai development of Drosophila melanogaster. Genetics 122, 429-438.
44. Simpson, P. (1990). Notch and the choice of cell fate in Drosophila neuroepithelium. Trends Genet. 6, 343-345.
45. Singson, A., Leviten, M.W., Bang, A.G., Hua, X.A., and Posakony, J.W. (1994). Direct downstream targets of proneural activators in the imaginal disc include genes involved in lateral inhibitory signaling. Genes Dev. 8, 2058-2071.
46. Skeath, J.B., and Carroll, S.B. (1992). Regulation of proneural gene expression and cell fate during neuroblast segregation in the Drosophila embryo. Development 114, 939-946.
47. Skeath, J.B., Panganiban, G., Selegue, J., and Carroll, S.B. (1992). Gene regulation in two dimensions: proneural achaete and scuta genes are controlled by combinations of axis-patterning genes through a common intergenic control region. Genes Dev. 6, 2606-2619.
48. Skeath J.B., Panganiban, G.F., and Carroll, S.B. (1994). The ventral nervous system defective gene controls proneural gene expression at two distinct steps during neuroblast formation in Drosophila. Development 120, 1517-1524.
49. Struhl, G., Fitzgerald, K., and Greenwald, I. (1993). Intrinsic activity of Lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.
50. Tata, F., and Hartley, D.A. (1995). Inhibition of cell fate in Drosophila by Enhancer of split genes. Mech. Dev. 51, 305-315.
51. Tautz, D., and Pfeifle, C. (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.
52. Tietze, K., Oellers, N., and Knust, E. (1992) Enhancer of splitD, a dominant mutation of Drosophila and its use in the study of functional domains of a helix-loop-helix protein. Proc. Natl. Acad. Sci. USA 89, 6152-6156.
53. Treacy, M.N., Neilson, L., Turner, E.E., He, X., and Rosenfeld, M.G. (1992). Twin of I-POU: A two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription. Cell 65, 491-505.
54. Usui, K., and Kimura, K.-I. (1992). Sensory mother cells are selected from among mitotically quiescent cluster of cells in the wing disc of Drosophila. Development 116, 601-610.
55. Vaessin, H., Brand, M., Jan, L.Y., and Jan, Y.N. (1994). daughterless is essential for neuronal precursor differentiation but not for initiation of neuronal precursor formation in Drosophila embryo. Development 120, 935-945.
56. Van der Meer, J. (1977). Optical clean and permanent mount preparations for phase contrast microscopy of cuticular structures of insect larvae. Drosophila Inf. Serv. 52, 160.
57. Van Doren, M., Baily, A.M., Esnayra, J., Ede, K., and Posakony, J.W. (1994). Negative regulation of proneural gene activity: hairy is a direct transcriptional repressor of achaete. Genes Dev. 8, 2729-2742.
58. White, K. (1980). Defective neural development in Drosophila melanogaster embryos deficient for the tip of the X-chromosome. Dev. Biol. 80, 322-344.
59. Wodarz, A., Hinz, U., Engelbert, M., and Knust, E. (1995). Expression of crumbs confers apical character on plasma membrane domains of ectodermal epithelia of Drosophila. Cell 82, 67-76.