Temporal correlation analysis of penumbral dynamics in focal cerebral ischemia

Journal of Cerebral Blood Flow and Metabolism

Volumn 16, Issue 1, 1996, Pages 60-68

  Lo, E H ^a   Rogowska, J ^a   Bogorodzki, P ^a   Trocha, M ^a   Matsumoto, K ^a   Saffran, B ^a   Wolf, G L ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cerebral blood flow; Dynamic computed tomography; Functional imaging; Ischemic penumbra

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN ISCHEMIA; BRAIN MAPPING; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG METABOLISM; FUNCTIONAL ANATOMY; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT;

EID: 0030029848     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004647-199601000-00007     Document Type: Article

References (45)

1. An G, Lin T, Liu JS, Xue JJ, He YY, Hsu CY (1993) Expression of c-fos and c-jun family genes after focal cerebral ischemia. Ann Neural 33:457-464
2. Araki Y, Mori S, Kawai R, Mitomo M (1987) Cerebral peak time mapping: uniformity of the value of the peak time. Neuroradiology 29:160-162
3. Astrup J, Siesjö BK, Symon L (1981) Thresholds in cerebral ischemia: the ischemic penumbra. Stroke 12:723-725
4. + at critical levels of brain ischemia. Stroke 8:51-57
5. Axel L (1980) Cerebral blood flow determination by rapid sequence computed tomography. Radiology 137:679-686
6. Baron JC, Frackowiak RSJ, Herholz K, Jones T, Lammertsma AA, Mazoyer B, Wienhard K (1989) Use of PET methods for measurement of cerebral energy metabolism and hemodynamics in cerebrovascular disease. J Cereb Blood Flow Metab 9:723-742
7. Berninger WH, Axel L, Norman D, Napel S, Redington RW (1981) Functional imaging of the brain using computed tomography. Radiology 138:711-716
8. del Zoppo GJ (1994) Microvascular changes during cerebral ischemia and reperfusion. Cerebrovasc Brain Metab Rev 6:47-96
9. Fischman AJ, Lo EH, Rosen BR (1995) Cerebrovascular and metabolic imaging. In: Handbook of Targeted Delivery of Imaging Agents (Torchilin V, ed), Boca Raton, CRC Press pp. 537-552
10. Girgis M, Wang SC (1988) A New Stereotactic Atlas of the Rabbit Brain. St. Louis, Warren Green
11. Hakim AM, Hogan MI, Carpenter S (1992) Time course of cerebral blood flow and histological outcome after focal cerebral ischemia in rats. Stroke 23:1138-1144
12. Hamberg LM, MacFarlane R, Tasdemirolgu E, Boccalini P, Hunter GJ, Belliveau JW, Moskowitz MA, Rosen BR (1993) Measurement of cerebrovascular changes in cats after transient ischemia using dynamic MRI. Stroke 24:444-451
13. Heiss WD (1992) Experimental evidence of ischemic thresholds and functional recovery. Stroke 23:1668-1672
14. Heiss WD, Graf R, Weinhard K, Lottgen J, Sito R, Fujita T, Rosner G, Wagner R (1994) Dynamic penumbra demonstrated by sequential multitracer PET after MCAO in cats. J Cereb Blood Flow Metab 14:892-902
15. Jones TH, Morawetz RB, Crowell RM, Marcoux FW, Fitzgibbon SJ, De Girolami U, Ojemann RG (1981) Threshold of focal cerebral ischemia in awake monkeys. J Neurosurg 54:773-782
16. Kaplan B, Brint S, Tanabe J, Jacewicz M, Wang XJ, Pulsinelli W (1991) Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia. Stroke 22:1032-1039
17. Kinouchi H, Sharp FR, Chan PH, Koistinaho J, Sagar SM, Yoshimoto T (1994) Induction of c-fos, junB, c-jun, and hsp70 mRNA in cortex, thalamus, basal ganglia, and hippo-campus following MCA occlusion. J Cereb Blood Flow Metab 14:808-817
18. Kucharczyk J, Mintorovich J, Moseley ME, Asgari HS, Sevick RJ, Derugin N, Norman D (1991) Ischemic brain damage: reduction by sodium-calcium ion channel modulator RS-87476. Radiology 179:221-227
19. Lo EH, Steinberg GK (1991) Effects of dextromethorphan on regional cerebral blood flow in focal cerebral ischemia. J Cereb Blood Flow Metab 11:803-811
20. Lo EH, Steinberg GK (1992) Effects of hypothermia on evoked potentials, MRI and cerebral blood flow in rabbit focal ischemia. Stroke 23:889-895
21. Lo EH, Steinberg GK, Panahian NM, Maidment NT, Newcomb R (1993) Profiles of extracellular amino acid changes in focal cerebral ischemia: effects of mild hypothermia. Neurol Res 15:281-289
22. Lo EH, Matsumoto K, Pierce AR, Garrido L, Luttinger D (1994a) Pharmacologic reversal of acute changes in diffusion-weighted magnetic resonance imaging in focal cerebral ischemia. J Cereb Blood Flow Metab 14:597-603
23. Lo EH, Pan Y, Matsumoto K, Kowall NW (1994b) Blood-brain barrier disruption in experimental focal ischemia: comparison between in vivo MRI and immunocytochemistry. Magn Res Imag 12:403-411
24. Matthews VP, Barker PB, Bryan RN (1992) Magnetic resonance evaluation of stroke. Magn Res Q 8:245-268
25. Memezawa H, Smith ML, Siesjö BK (1992) Penumbral tissues salvaged by reperfusion following middle cerebral artery occlusion in rats. Stroke 23:552-560
26. Mies G, Ishimaru S, Xie Y, Seo K, Hossmann K-A (1991) Ischemic thresholds of cerebral protein synthesis and energy state following middle cerebral artery occlusion in rat. J Cereb Blood Flow Metab 11:753-761
27. Minematsu K, Fisher M, Li L, Davis MA, Knapp AG, Cotter RE, McBurney RN, Sotak C (1993) Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology 43:397-102
28. Nagata K, Asano T (1990) Functional image of dynamic computed tomography for the evaluation of cerebral hemodynamics. Stroke 21:882-889
29. Nedergaard M (1987) Neuronal injury in the infarct border: a neuropathological study in rat. Acta Neuropathol 73:267-274
30. Nishikawa T, Kirsch JR, Koehler RC, Bredt BS, Snyder SH, Traystman RJ (1993) Effect of nitric oxide synthase inhibition on cerebral blood flow and injury volume during focal ischemia in cats. Stroke 24:1717-1724
31. Norman D, Axel L, Berninger WH, Edwards MS, Cann CE, Redington RW, Cox L (1981) Dynamic computed tomography of the brain: techniques, data analysis and applications. AJR 136:759-770
32. Powers WJ (1991) Cerebral hemodynamics in ischemic cerebrovascular disease. Ann Neurol 29:231-240
33. Roberts TPL, Vexler Z, Derugin N, Moseley ME, Kucharczyk J (1993) High-speed MRI of ischemic brain injury following stenosis of the middle cerebral artery. J Cereb Blood Flow Metab 13:940-946
34. Rogowska J, Wolf GL (1992) Temporal correlation images derived from sequential MR scans. J Comput Assist Tomogr 16:784-788
35. Rogowska J, Hamberg LM, Hunter GJ, Aronen HJ, Wolf GL (1992) Biological applications of correlation maps for the analysis of dynamic susceptibility contrast MRI series data. Soc Magn Res Med 11:47
36. Rogowska J, Preston K, Aronen HJ, Wolf GL (1994) A comparative analysis of similarity mapping and eigenimaging as applied to dynamic MRI of a low-grade astrocytoma. Acta Radiol 35:371-377
37. Rogowska J, Preston K, Hunter GL, Hamberg L, Kwong KK, Salonen O (1995) Applications of similarity mapping in dynamic MRI. IEEE Trans Med Imag (in press)
38. Rosen BR, Belliveau JW, Aronen HJ, Hamberg LM, Kwong K, Fordham J (1994) Functional neuroimaging. In: Magnetic Resonance Neuroimaging (Kucharcyk J, Moseley MA, Barkovich A, eds), Boca Raton, CRC Press, pp 141-167
39. Steinberg GK, Lo EH, Kunis DM, Grant GA, DeLaPaz RL, Poljak A (1991) Dextromethorphan alters cerebral blood flow and protects against cerebral injury following focal ischemia. Neurosci Lett 133:225-228
40. Symon L (1987) Pathological regulation in cerebral ischemia. In: Cerebral Blood Flow: Physiologic and Clinical Aspects (Wood J, ed), New York, McGraw-Hill, pp 413-424
41. Takahashi N, Kikuchi H, Karasawa J (1983) Dynamic CT in patients with superficial temporal-middle cerebral artery anastomosis. AJNR 4:454-457
42. Torvik A, Svindland A (1986) Is there a transitional zone between brain infarcts and the surrounding brain? Acta Neurol Scand 74:365-370
43. Tyson GW, Teasdale GM, Graham DI, McCulloch J (1984) Focal cerebral ischemia in the rat: topography of hemodynamic and histopathological changes. Ann Neurol 15:559-567
44. Weisskoff RM, Chesler D, Boxerman JL, Rosen BR (1993) Pitfalls in MR measurement of tissue blood flow with intravascular tracers: which mean transit time? Magn Res Med 29: 553-559
45. Zierler KL (1962) Theoretical basis for indicator dilution methods for measuring flow and volume. Circ Res 10:393-407