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Volumn 7, Issue 4, 1998, Pages 229-237

Glucocorticoids: Mechanisms of action and anti-inflammatory potential in asthma

Author keywords

Asthma; Bronchial epithelial cells; Glucocorticoids; Inflammation

Indexed keywords

CELL ADHESION MOLECULE; CHEMOKINE; CYTOKINE; ENDOTHELIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR AP 1;

EID: 0031656612     PISSN: 09629351     EISSN: None     Source Type: Journal    
DOI: 10.1080/09629359890910     Document Type: Review
Times cited : (161)

References (173)
  • 2
    • 0027376537 scopus 로고
    • Efficacy and safety of inhaled corticosteroids in asthma
    • Barnes PJ, Pedersen S. Efficacy and safety of inhaled corticosteroids in asthma. Am Rev Respir Dis 1993; 148: S1-S26.
    • (1993) Am Rev Respir Dis , vol.148
    • Barnes, P.J.1    Pedersen, S.2
  • 3
    • 0022393794 scopus 로고
    • Primary structure and expression of a functional human glucocorticoid receptor cDNA
    • Hollenberg SM, Weinberger C, Ong ES, et al. Primary structure and expression of a functional human glucocorticoid receptor cDNA. Nature 1985; 318: 635-641.
    • (1985) Nature , vol.318 , pp. 635-641
    • Hollenberg, S.M.1    Weinberger, C.2    Ong, E.S.3
  • 4
    • 0023649571 scopus 로고
    • Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor
    • Hollenberg SM, Giguere V, Segui P, Evans RM. Colocalization of DNA-binding and transcriptional activation functions in the human glucocorticoid receptor. Cell 1987; 49: 39-46.
    • (1987) Cell , vol.49 , pp. 39-46
    • Hollenberg, S.M.1    Giguere, V.2    Segui, P.3    Evans, R.M.4
  • 5
    • 0022773520 scopus 로고
    • Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor
    • Kumar V, Green S, Staub A, Chambon P. Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J 1986; 5: 2231-2236.
    • (1986) EMBO J , vol.5 , pp. 2231-2236
    • Kumar, V.1    Green, S.2    Staub, A.3    Chambon, P.4
  • 6
    • 0023340611 scopus 로고
    • Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor
    • Rusconi S, Yamamoto KR. Functional dissection of the hormone and DNA binding activities of the glucocorticoid receptor. EMBO J 1987; 6: 1309-1315.
    • (1987) EMBO J , vol.6 , pp. 1309-1315
    • Rusconi, S.1    Yamamoto, K.R.2
  • 7
    • 0023913120 scopus 로고
    • The steroid and thyroid hormone receptor superfamily
    • Evans RM. The steroid and thyroid hormone receptor superfamily. Science 1988; 240: 889-895.
    • (1988) Science , vol.240 , pp. 889-895
    • Evans, R.M.1
  • 8
    • 0024153680 scopus 로고
    • Cooperative and positional independent trans-activation domains of the human glucocorticoid receptor
    • Evans RM, Hollenberg SM. Cooperative and positional independent trans-activation domains of the human glucocorticoid receptor. Cold Spring Harb Symp Quant Biol 1988; 53: 813-818.
    • (1988) Cold Spring Harb Symp Quant Biol , vol.53 , pp. 813-818
    • Evans, R.M.1    Hollenberg, S.M.2
  • 9
    • 0023441954 scopus 로고
    • Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor
    • Picard D, Yamamoto KR. Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J 1987; 6: 3333-3340.
    • (1987) EMBO J , vol.6 , pp. 3333-3340
    • Picard, D.1    Yamamoto, K.R.2
  • 10
    • 0023808861 scopus 로고
    • The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer
    • Kumar V, Chambon P. The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell 1988; 55: 145-156.
    • (1988) Cell , vol.55 , pp. 145-156
    • Kumar, V.1    Chambon, P.2
  • 11
    • 0023769378 scopus 로고
    • The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain
    • Freedman LP, Luisi BF, Korszun ZR, Basavappa R, Sigler PB, Yamamoto KR. The function and structure of the metal coordination sites within the glucocorticoid receptor DNA binding domain. Nature 1988; 334: 543-546.
    • (1988) Nature , vol.334 , pp. 543-546
    • Freedman, L.P.1    Luisi, B.F.2    Korszun, Z.R.3    Basavappa, R.4    Sigler, P.B.5    Yamamoto, K.R.6
  • 12
    • 0026685062 scopus 로고
    • Anatomy of the steroid receptor zinc finger region
    • Freedman LP. Anatomy of the steroid receptor zinc finger region. Endocr Rev 1992; 13: 129-145.
    • (1992) Endocr Rev , vol.13 , pp. 129-145
    • Freedman, L.P.1
  • 14
    • 0024744568 scopus 로고
    • Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities
    • Schena M, Freedman LP, Yamamoto KR. Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional enhancement activities. Genes Dev 1989; 3: 1590-1601.
    • (1989) Genes Dev , vol.3 , pp. 1590-1601
    • Schena, M.1    Freedman, L.P.2    Yamamoto, K.R.3
  • 15
    • 0028398040 scopus 로고
    • The anti-inflammatory activity of glucocorticoids
    • de Waal RM. The anti-inflammatory activity of glucocorticoids. Mol Biol Rep 1994; 19: 81-88.
    • (1994) Mol Biol Rep , vol.19 , pp. 81-88
    • De Waal, R.M.1
  • 16
    • 0025895395 scopus 로고
    • The genomic structure of the human glucocorticoid receptor
    • Encio IJ, Detera-Wadleigh SD. The genomic structure of the human glucocorticoid receptor. J Biol Chem 1991; 266: 7182-7188.
    • (1991) J Biol Chem , vol.266 , pp. 7182-7188
    • Encio, I.J.1    Detera-Wadleigh, S.D.2
  • 17
    • 0030664771 scopus 로고    scopus 로고
    • Absence of glucocorticoid receptor-beta in mice
    • Otto C, Reichardt HM, Schutz G. Absence of glucocorticoid receptor-beta in mice. J Biol Chem 1997; 272: 26665-26668.
    • (1997) J Biol Chem , vol.272 , pp. 26665-26668
    • Otto, C.1    Reichardt, H.M.2    Schutz, G.3
  • 18
    • 0030691015 scopus 로고    scopus 로고
    • Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant represser
    • Hecht K, Carlstedt-Duke J, Stierna P, Gustafsson J, Bronnegard M, Wikstrom AC. Evidence that the beta-isoform of the human glucocorticoid receptor does not act as a physiologically significant represser. J Biol Chem 1997; 272: 26659-26664.
    • (1997) J Biol Chem , vol.272 , pp. 26659-26664
    • Hecht, K.1    Carlstedt-Duke, J.2    Stierna, P.3    Gustafsson, J.4    Bronnegard, M.5    Wikstrom, A.C.6
  • 19
    • 0030774245 scopus 로고    scopus 로고
    • Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor
    • Oakley RH, Webster JC, Sar M, Parker CR, Jr, Cidlowski JA. Expression and subcellular distribution of the beta-isoform of the human glucocorticoid receptor. Endocrinology 1997; 138: 5028-5038.
    • (1997) Endocrinology , vol.138 , pp. 5028-5038
    • Oakley, R.H.1    Webster, J.C.2    Sar, M.3    Parker Jr., C.R.4    Cidlowski, J.A.5
  • 20
  • 21
    • 0029757679 scopus 로고    scopus 로고
    • Steroid receptor number. Individual variation and downregulation by treatment
    • Bronnegard M. Steroid receptor number. Individual variation and downregulation by treatment. Am J Respir Crit Care Med 1996; 154: S28-S32.
    • (1996) Am J Respir Crit Care Med , vol.154
    • Bronnegard, M.1
  • 23
    • 0030894724 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of alpha- and beta-glucocorticoid-receptor mRNA in human bronchial epithelium
    • Korn SH, Wouters EF, Wesseling G, Arends JW, Thunnissen FB. In vitro and in vivo modulation of alpha- and beta-glucocorticoid-receptor mRNA in human bronchial epithelium. Am J Respir Crit Care Med 1997; 155: 1117-1122.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1117-1122
    • Korn, S.H.1    Wouters, E.F.2    Wesseling, G.3    Arends, J.W.4    Thunnissen, F.B.5
  • 24
    • 0027242280 scopus 로고
    • Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids
    • Kam JC, Szefler SJ, Surs W, Sher ER, Leung DY. Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol 1993; 151: 3460-3466.
    • (1993) J Immunol , vol.151 , pp. 3460-3466
    • Kam, J.C.1    Szefler, S.J.2    Surs, W.3    Sher, E.R.4    Leung, D.Y.5
  • 25
    • 0027319435 scopus 로고
    • Modulation of glucocorticosteroid binding in human lymphoid, monocytoid and hepatoma cell lines by inflammatory cytokines interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha
    • Rakasz E, Gal A, Biro J, Balas G, Falus A. Modulation of glucocorticosteroid binding in human lymphoid, monocytoid and hepatoma cell lines by inflammatory cytokines interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha. Scand J Immunol 1993; 37: 684-689.
    • (1993) Scand J Immunol , vol.37 , pp. 684-689
    • Rakasz, E.1    Gal, A.2    Biro, J.3    Balas, G.4    Falus, A.5
  • 26
    • 0027101803 scopus 로고
    • Lipopolysaccharide increases glucocorticoid receptor expression in murine macrophages. A possible mechanism for glucocorticoid-mediated suppression of endotoxicity
    • Salkowski CA, Vogel SN. Lipopolysaccharide increases glucocorticoid receptor expression in murine macrophages. A possible mechanism for glucocorticoid-mediated suppression of endotoxicity. J Immunol 1992; 149: 4041-4047.
    • (1992) J Immunol , vol.149 , pp. 4041-4047
    • Salkowski, C.A.1    Vogel, S.N.2
  • 27
    • 0026557524 scopus 로고
    • IFN-gamma mediates increased glucocorticoid receptor expression in murine macrophages
    • Salkowski CA, Vogel SN. IFN-gamma mediates increased glucocorticoid receptor expression in murine macrophages. J Immunol 1992; 148: 2770-2777.
    • (1992) J Immunol , vol.148 , pp. 2770-2777
    • Salkowski, C.A.1    Vogel, S.N.2
  • 28
    • 0029784798 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor expression in human bronchial epithelial cell lines by IL-1 beta, TNF-alpha and LPS
    • Verheggen MM, van Hal PT, Adriaansen-Soeting PW, et al. Modulation of glucocorticoid receptor expression in human bronchial epithelial cell lines by IL-1 beta, TNF-alpha and LPS. Eur Respir J 1996; 9: 2036-2043.
    • (1996) Eur Respir J , vol.9 , pp. 2036-2043
    • Verheggen, M.M.1    Van Hal, P.T.2    Adriaansen-Soeting, P.W.3
  • 30
    • 0023338533 scopus 로고
    • Biochemistry, molecular biology, and physiology of the glucocorticoid receptor
    • Gustafsson JA, Carlstedt-Duke J, Poellinger L, et al. Biochemistry, molecular biology, and physiology of the glucocorticoid receptor. Endocr Rev 1987; 8: 185-234.
    • (1987) Endocr Rev , vol.8 , pp. 185-234
    • Gustafsson, J.A.1    Carlstedt-Duke, J.2    Poellinger, L.3
  • 31
    • 0023937216 scopus 로고
    • Isoform composition and stoichiometry of the approximately 90-kDa heat shock protein associated with glucocorticoid receptors
    • Mendel DB, Orti E. Isoform composition and stoichiometry of the approximately 90-kDa heat shock protein associated with glucocorticoid receptors. J Biol Chem 1988; 263: 6695-6702.
    • (1988) J Biol Chem , vol.263 , pp. 6695-6702
    • Mendel, D.B.1    Orti, E.2
  • 32
    • 0026543821 scopus 로고
    • Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events
    • Smith DF, Stensgard BA, Welch WJ, Toft DO. Assembly of progesterone receptor with heat shock proteins and receptor activation are ATP mediated events. J Biol Chem 1992; 267: 1350-1356.
    • (1992) J Biol Chem , vol.267 , pp. 1350-1356
    • Smith, D.F.1    Stensgard, B.A.2    Welch, W.J.3    Toft, D.O.4
  • 33
    • 0025605444 scopus 로고
    • Hsp56: A novel heat shock protein associated with untransformed steroid receptor complexes
    • Sanchez ER. Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes. J Biol Chem 1990; 265: 22067-22070.
    • (1990) J Biol Chem , vol.265 , pp. 22067-22070
    • Sanchez, E.R.1
  • 34
    • 0026781440 scopus 로고
    • P59, an hsp 90-binding protein, Cloning and sequencing of its cDNA and prepration of a peptide-directed polyclonal antibody
    • Lebeau MC, Massol N, Herrick J, et al. P59, an hsp 90-binding protein, Cloning and sequencing of its cDNA and prepration of a peptide-directed polyclonal antibody. J Biol Chem 1992; 267: 4281-4284.
    • (1992) J Biol Chem , vol.267 , pp. 4281-4284
    • Lebeau, M.C.1    Massol, N.2    Herrick, J.3
  • 35
    • 0027249002 scopus 로고
    • Steroid hormone receptors: Interaction with deoxyribonucleic acid and transcription factors
    • Truss M, Beato M. Steroid hormone receptors: interaction with deoxyribonucleic acid and transcription factors. Endocr Rev 1993; 14: 459-479.
    • (1993) Endocr Rev , vol.14 , pp. 459-479
    • Truss, M.1    Beato, M.2
  • 36
    • 0024545638 scopus 로고
    • Gene regulation by steroid hormones
    • Beato M. Gene regulation by steroid hormones. Cell 1989; 56: 335-344.
    • (1989) Cell , vol.56 , pp. 335-344
    • Beato, M.1
  • 37
    • 0025130179 scopus 로고
    • Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
    • Schule R, Rangarajan P, Kliewer S, et al. Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor. Cell 1990; 62: 1217-1226.
    • (1990) Cell , vol.62 , pp. 1217-1226
    • Schule, R.1    Rangarajan, P.2    Kliewer, S.3
  • 38
    • 0242490975 scopus 로고
    • Synergistic action of the glucocorticoid receptor with transcription factors
    • Strahle U, Schmid W, Schutz G. Synergistic action of the glucocorticoid receptor with transcription factors. EMBO J 1988; 7: 3389-3395.
    • (1988) EMBO J , vol.7 , pp. 3389-3395
    • Strahle, U.1    Schmid, W.2    Schutz, G.3
  • 39
    • 0029737089 scopus 로고    scopus 로고
    • Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids
    • Didonato JA, Saatcioglu F, Karin M. Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids. Am J Respir Crit Care Med 1996; 154: S11-S15.
    • (1996) Am J Respir Crit Care Med , vol.154
    • Didonato, J.A.1    Saatcioglu, F.2    Karin, M.3
  • 40
    • 0020550742 scopus 로고
    • Enhancer elements activated by steroid hormones?
    • Parker M. Enhancer elements activated by steroid hormones? Nature 1983; 304: 687-688.
    • (1983) Nature , vol.304 , pp. 687-688
    • Parker, M.1
  • 41
    • 0021491117 scopus 로고
    • Tissue-specific DNaseI hypersensitive sites in the 5′-flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes
    • Becker P, Renkawitz R, Schutz G. Tissue-specific DNaseI hypersensitive sites in the 5′-flanking sequences of the tryptophan oxygenase and the tyrosine aminotransferase genes. EMBO J 1984; 3: 2015-2020.
    • (1984) EMBO J , vol.3 , pp. 2015-2020
    • Becker, P.1    Renkawitz, R.2    Schutz, G.3
  • 42
    • 0021250441 scopus 로고
    • Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme gene
    • Fritton HP, Igo-Kemenes T, Nowock J, Strech-Jurk U, Theisen M, Sippel AE. Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme gene. Nature 1984; 311: 163-165.
    • (1984) Nature , vol.311 , pp. 163-165
    • Fritton, H.P.1    Igo-Kemenes, T.2    Nowock, J.3    Strech-Jurk, U.4    Theisen, M.5    Sippel, A.E.6
  • 43
    • 0021745342 scopus 로고
    • Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element
    • Zaret KS, Yamamoto KR. Reversible and persistent changes in chromatin structure accompany activation of a glucocorticoid-dependent enhancer element. Cell 1984; 38: 29-38.
    • (1984) Cell , vol.38 , pp. 29-38
    • Zaret, K.S.1    Yamamoto, K.R.2
  • 44
    • 0024095841 scopus 로고
    • Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome
    • Perlmann T, Wrange O. Specific glucocorticoid receptor binding to DNA reconstituted in a nucleosome. EMBO J 1988; 7: 3073-3079.
    • (1988) EMBO J , vol.7 , pp. 3073-3079
    • Perlmann, T.1    Wrange, O.2
  • 45
    • 0030031449 scopus 로고    scopus 로고
    • Molecular mechanisms of steroid action in asthma
    • Barnes PJ. Molecular mechanisms of steroid action in asthma. J Allergy Clin Immunol 1996; 97: 159-168.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 159-168
    • Barnes, P.J.1
  • 46
    • 0025258893 scopus 로고
    • Nuclear proto-oncogenes fos and jun
    • Ransone LJ, Verma IM. Nuclear proto-oncogenes fos and jun. Annu Rev Cell Biol 1990; 6: 539-557.
    • (1990) Annu Rev Cell Biol , vol.6 , pp. 539-557
    • Ransone, L.J.1    Verma, I.M.2
  • 47
    • 0025720735 scopus 로고
    • The role of Jun, Fos and the AP-I complex in cell-proliferation and transformation
    • Angel P, Karin M. The role of Jun, Fos and the AP-I complex in cell-proliferation and transformation. Biochim Biophys Acta 1991; 1072: 129-157.
    • (1991) Biochim Biophys Acta , vol.1072 , pp. 129-157
    • Angel, P.1    Karin, M.2
  • 48
    • 0025015647 scopus 로고
    • Antitumor promotion and antiinflammation: Down-modulation of AP-I (Fos/Jun) activity by glucocorticoid hormone
    • Jonat C, Rahmsdorf HJ, Park KK, et al. Antitumor promotion and antiinflammation: down-modulation of AP-I (Fos/Jun) activity by glucocorticoid hormone. Cell 1990; 62: 1189-1204.
    • (1990) Cell , vol.62 , pp. 1189-1204
    • Jonat, C.1    Rahmsdorf, H.J.2    Park, K.K.3
  • 49
    • 0025188132 scopus 로고
    • Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
    • Yang-Yen HF, Chambard JC, Sun YL, et al. Transcriptional interference between c-Jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 1990; 62: 1205-1215.
    • (1990) Cell , vol.62 , pp. 1205-1215
    • Yang-Yen, H.F.1    Chambard, J.C.2    Sun, Y.L.3
  • 50
    • 0024475227 scopus 로고
    • NF-kappa B: A pleiotropic mediator of inducible and tissue-specific gene control
    • Lenardo MJ, Baltimore D. NF-kappa B: a pleiotropic mediator of inducible and tissue-specific gene control. [Review]. Cell 1989; 58: 227-229.
    • (1989) Cell , vol.58 , pp. 227-229
    • Lenardo, M.J.1    Baltimore, D.2
  • 51
    • 0028107237 scopus 로고
    • Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor
    • Ray A, Prefontaine KE. Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci USA 1994; 91: 752-756.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 752-756
    • Ray, A.1    Prefontaine, K.E.2
  • 52
    • 0027232067 scopus 로고
    • NF-kappa B and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M, Chiu JJ, Lenardo MJ. NF-kappa B and Rel: participants in a multiform transcriptional regulatory system. Int Rev Cytol 1993; 143: 1-62.
    • (1993) Int Rev Cytol , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 53
  • 54
    • 0028867899 scopus 로고
    • Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
    • Auphan N, DiDonato JA, Rosette C, Helmberg A, Karin M. Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 1995; 270: 286-290.
    • (1995) Science , vol.270 , pp. 286-290
    • Auphan, N.1    DiDonato, J.A.2    Rosette, C.3    Helmberg, A.4    Karin, M.5
  • 55
    • 0028879819 scopus 로고
    • Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids
    • Scheinman RI, Cogswell PC, Lofquist AK, Baldwin AS Jr Role of transcriptional activation of I kappa B alpha in mediation of immunosuppression by glucocorticoids. Science 1995; 270: 283-286.
    • (1995) Science , vol.270 , pp. 283-286
    • Scheinman, R.I.1    Cogswell, P.C.2    Lofquist, A.K.3    Baldwin Jr., A.S.4
  • 56
    • 0025812292 scopus 로고
    • Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity
    • Haskill S, Beg AA, Tompkins SM, et al. Characterization of an immediate-early gene induced in adherent monocytes that encodes I kappa B-like activity. Cell 1991; 65: 1281-1289.
    • (1991) Cell , vol.65 , pp. 1281-1289
    • Haskill, S.1    Beg, A.A.2    Tompkins, S.M.3
  • 57
    • 0028972845 scopus 로고
    • Mechanistic aspects of NF-kappa B regulation: The emerging role of phosphorylation and proteolysis
    • Finco TS, Baldwin AS. Mechanistic aspects of NF-kappa B regulation: the emerging role of phosphorylation and proteolysis. Immunity 1995; 3: 263-372.
    • (1995) Immunity , vol.3 , pp. 263-372
    • Finco, T.S.1    Baldwin, A.S.2
  • 58
    • 0028305712 scopus 로고
    • Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression
    • Mukaida N, Morita M, Ishikawa Y, et al. Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression. J Biol Chem 1994; 269: 13289-13295.
    • (1994) J Biol Chem , vol.269 , pp. 13289-13295
    • Mukaida, N.1    Morita, M.2    Ishikawa, Y.3
  • 59
    • 0028909667 scopus 로고
    • Negative cross-talk between RelA and the glucocorticoid receptor: A possible mechanism for the antiinflammatory action of glucocorticoids
    • Caldenhoven E, Liden J, Wissink S, et al. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol Endocrinol 1995; 9: 401-412.
    • (1995) Mol Endocrinol , vol.9 , pp. 401-412
    • Caldenhoven, E.1    Liden, J.2    Wissink, S.3
  • 60
    • 0025021274 scopus 로고
    • Characterization of a bipartite activator domain in transcription factor CREB
    • Yamamoto KK, Gonzalez GA, Menzel P, Rivier J, Montminy MR. Characterization of a bipartite activator domain in transcription factor CREB. Cell 1990; 60: 611-617.
    • (1990) Cell , vol.60 , pp. 611-617
    • Yamamoto, K.K.1    Gonzalez, G.A.2    Menzel, P.3    Rivier, J.4    Montminy, M.R.5
  • 61
    • 0030048013 scopus 로고    scopus 로고
    • Interactions of glucocorticoids and beta 2-agonists
    • Adcock IM, Stevens DA, Barnes PJ. Interactions of glucocorticoids and beta 2-agonists. Eur Respir J 1996; 9: 160-168.
    • (1996) Eur Respir J , vol.9 , pp. 160-168
    • Adcock, I.M.1    Stevens, D.A.2    Barnes, P.J.3
  • 62
    • 0029031620 scopus 로고
    • High concentrations of beta-adrenergic agonists inhibit DNA binding of glucocorticoids in human lung in vitro
    • Adcock IM, Peters MJ, Brown CR, Stevens DA, Barnes PJ. High concentrations of beta-adrenergic agonists inhibit DNA binding of glucocorticoids in human lung in vitro. Biochem Soc Trans 1995; 23: 217S.
    • (1995) Biochem Soc Trans , vol.23
    • Adcock, I.M.1    Peters, M.J.2    Brown, C.R.3    Stevens, D.A.4    Barnes, P.J.5
  • 63
    • 0028960663 scopus 로고
    • Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung
    • Peters MJ, Adcock IM, Brown CR, Barnes PJ. Beta-adrenoceptor agonists interfere with glucocorticoid receptor DNA binding in rat lung. Eur J Pharmacol 1995; 289: 275-281.
    • (1995) Eur J Pharmacol , vol.289 , pp. 275-281
    • Peters, M.J.1    Adcock, I.M.2    Brown, C.R.3    Barnes, P.J.4
  • 64
    • 0026100340 scopus 로고
    • The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids
    • Peppel K, Vinci JM, Baglioni C. The AU-rich sequences in the 3′ untranslated region mediate the increased turnover of interferon mRNA induced by glucocorticoids. J Exp Med 1991; 173: 349-355.
    • (1991) J Exp Med , vol.173 , pp. 349-355
    • Peppel, K.1    Vinci, J.M.2    Baglioni, C.3
  • 65
    • 0000693107 scopus 로고
    • Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA
    • Lee SW, Tsou AP, Chan H, et al. Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA Proc Natl Acad Sci USA 1988; 85: 1204-1208.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1204-1208
    • Lee, S.W.1    Tsou, A.P.2    Chan, H.3
  • 66
    • 0029763302 scopus 로고    scopus 로고
    • The epithelium as a target of glucocorticoid action in the treatment of asthma
    • Schwiebert LM, Stellato C, Schleimer RP. The epithelium as a target of glucocorticoid action in the treatment of asthma. Am J Respir Crit Care Med 1996; 154: S16-S19.
    • (1996) Am J Respir Crit Care Med , vol.154
    • Schwiebert, L.M.1    Stellato, C.2    Schleimer, R.P.3
  • 68
    • 0026175977 scopus 로고
    • Promotion of eosinophil survival by human bronchial epithelial cells and its modulation by steroids
    • Cox G, Ohtoshi T, Vancheri C, et al. Promotion of eosinophil survival by human bronchial epithelial cells and its modulation by steroids. Am J Respir Cell Mol Biol 1991; 4: 525-531.
    • (1991) Am J Respir Cell Mol Biol , vol.4 , pp. 525-531
    • Cox, G.1    Ohtoshi, T.2    Vancheri, C.3
  • 69
    • 0026583649 scopus 로고
    • Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma
    • Marini M, Vittori E, Hollemborg J, Mattoli S. Expression of the potent inflammatory cytokines, granulocyte-macrophage-colony-stimulating factor and interleukin-6 and interleukin-8, in bronchial epithelial cells of patients with asthma. J Allergy Clin Immunol 1992; 89: 1001-1009.
    • (1992) J Allergy Clin Immunol , vol.89 , pp. 1001-1009
    • Marini, M.1    Vittori, E.2    Hollemborg, J.3    Mattoli, S.4
  • 70
    • 0029993396 scopus 로고    scopus 로고
    • Expression of RANTES in human airway epithelial cells: Effect of corticosteroids and interleukin-4, -10 and -13
    • Berkman N, Robichaud A, Krishnan VL, et al. Expression of RANTES in human airway epithelial cells: effect of corticosteroids and interleukin-4, -10 and -13. Immunology 1996; 87: 599-603.
    • (1996) Immunology , vol.87 , pp. 599-603
    • Berkman, N.1    Robichaud, A.2    Krishnan, V.L.3
  • 71
    • 0029063322 scopus 로고
    • Expression of the chemokine RANTES by a human bronchial epithelial cell line Modulation by cytokines and glucocorticoids
    • Stellato C, Beck LA, Gorgone GA, et al. Expression of the chemokine RANTES by a human bronchial epithelial cell line Modulation by cytokines and glucocorticoids. J Immunol 1995; 155: 410-418.
    • (1995) J Immunol , vol.155 , pp. 410-418
    • Stellato, C.1    Beck, L.A.2    Gorgone, G.A.3
  • 72
    • 0028024841 scopus 로고
    • Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells
    • Kwon OJ, Au BT, Collins PD, et al. Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells. Immunology 1994; 81: 389-394.
    • (1994) Immunology , vol.81 , pp. 389-394
    • Kwon, O.J.1    Au, B.T.2    Collins, P.D.3
  • 73
    • 0030942468 scopus 로고    scopus 로고
    • Expression of eotaxin by human lung epithelial cells: Induction by cytokines and inhibition by glucocorticoids
    • Lilly CM, Nakamura H, Kesselman H, et al. Expression of eotaxin by human lung epithelial cells: induction by cytokines and inhibition by glucocorticoids. J Clin Invest 1997; 99: 1767-1773.
    • (1997) J Clin Invest , vol.99 , pp. 1767-1773
    • Lilly, C.M.1    Nakamura, H.2    Kesselman, H.3
  • 74
    • 0027686133 scopus 로고
    • Release of interleukin-8, interleukin-6, and colony-stimulating factors by upper airway epithelial cells implications for cystic fibrosis
    • Bedard M, McClure CD, Schiller NL, Francoeur C, Cantin A, Denis M. Release of interleukin-8, interleukin-6, and colony-stimulating factors by upper airway epithelial cells implications for cystic fibrosis. Am J Respir Cell Mol Biol 1993; 9: 455-462.
    • (1993) Am J Respir Cell Mol Biol , vol.9 , pp. 455-462
    • Bedard, M.1    McClure, C.D.2    Schiller, N.L.3    Francoeur, C.4    Cantin, A.5    Denis, M.6
  • 76
    • 0027485803 scopus 로고
    • Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line
    • Levine SJ, Larivee P, Logun C, Angus CW, Shelhamer JH. Corticosteroids differentially regulate secretion of IL-6, IL-8, and G-CSF by a human bronchial epithelial cell line. Am J Physiol 1993; 265: L360-L368.
    • (1993) Am J Physiol , vol.265
    • Levine, S.J.1    Larivee, P.2    Logun, C.3    Angus, C.W.4    Shelhamer, J.H.5
  • 77
    • 0027176276 scopus 로고
    • Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids
    • Sousa AR, Poston RN, Lane SJ, Nakhosteen JA, Lee TH. Detection of GM-CSF in asthmatic bronchial epithelium and decrease by inhaled corticosteroids. Am Rev Respir Dis 1993; 147: 1557-1561.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 1557-1561
    • Sousa, A.R.1    Poston, R.N.2    Lane, S.J.3    Nakhosteen, J.A.4    Lee, T.H.5
  • 78
    • 0030975083 scopus 로고    scopus 로고
    • Effect of inhaled glucocorticoids on IL-1 beta and IL-1 receptor antagonist (IL-1 ra) expression in asthmatic bronchial epithelium
    • Sousa AR, Trigg CJ, Lane SJ, et al. Effect of inhaled glucocorticoids on IL-1 beta and IL-1 receptor antagonist (IL-1 ra) expression in asthmatic bronchial epithelium. Thorax 1997; 52: 407-410.
    • (1997) Thorax , vol.52 , pp. 407-410
    • Sousa, A.R.1    Trigg, C.J.2    Lane, S.J.3
  • 79
    • 0028240265 scopus 로고
    • Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma
    • Trigg CJ, Manolitsas ND, Wang J, et al. Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma. Am J Respir Crit Care Med 1994; 150: 17-22.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 17-22
    • Trigg, C.J.1    Manolitsas, N.D.2    Wang, J.3
  • 80
    • 0029687796 scopus 로고    scopus 로고
    • Expression of RANTES by human bronchial epithelial cells in vitro and in vivo and the effect of corticosteroids
    • Wang JH, Devalia JL, Xia C, Sapsford RJ, Davies RJ. Expression of RANTES by human bronchial epithelial cells in vitro and in vivo and the effect of corticosteroids. Am J Respir Cell Mol Biol 1996; 14: 27-35.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 27-35
    • Wang, J.H.1    Devalia, J.L.2    Xia, C.3    Sapsford, R.J.4    Davies, R.J.5
  • 81
    • 0029360587 scopus 로고
    • Substance P (NK1)- and neurokinin A (NK2)-receptor gene expression in inflammatory airway diseases
    • Bai TR, Zhou D, Weir T, et al. Substance P (NK1)- and neurokinin A (NK2)-receptor gene expression in inflammatory airway diseases. Am J Physiol 1995; 269: L309-L317.
    • (1995) Am J Physiol , vol.269
    • Bai, T.R.1    Zhou, D.2    Weir, T.3
  • 83
    • 0029115523 scopus 로고
    • Protective effects of a glucocorticoid on downregulation of pulmonary beta 2-adrenergic receptors in vivo
    • Mak JC, Nishikawa M, Shirasaki H, Miyayasu K, Barnes PJ. Protective effects of a glucocorticoid on downregulation of pulmonary beta 2-adrenergic receptors in vivo. J Clin Invest 1995; 96: 99-106.
    • (1995) J Clin Invest , vol.96 , pp. 99-106
    • Mak, J.C.1    Nishikawa, M.2    Shirasaki, H.3    Miyayasu, K.4    Barnes, P.J.5
  • 84
    • 0030860288 scopus 로고    scopus 로고
    • Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics
    • Tan S, Hall IP, Dewar J, Dow E, Lipworth B. Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics. Lancet 1997; 350: 995-999.
    • (1997) Lancet , vol.350 , pp. 995-999
    • Tan, S.1    Hall, I.P.2    Dewar, J.3    Dow, E.4    Lipworth, B.5
  • 85
    • 0027181936 scopus 로고
    • Interleukin-1 type II receptor: A decoy target for IL-1 that is regulated by IL-4
    • Colotta F, Re F, Muzio M, et al. Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science 1993; 261: 472-475.
    • (1993) Science , vol.261 , pp. 472-475
    • Colotta, F.1    Re, F.2    Muzio, M.3
  • 87
    • 0028179247 scopus 로고
    • The type II 'receptor' as a decoy target for interleukin 1 in polymorphonuclear leukocytes: Characterization of induction by dexamethasone and ligand binding properties of the released decoy receptor
    • Re F, Muzio M, De Rossi M, et al. The type II 'receptor' as a decoy target for interleukin 1 in polymorphonuclear leukocytes: characterization of induction by dexamethasone and ligand binding properties of the released decoy receptor. J Exp Med 1994; 179: 739-743.
    • (1994) J Exp Med , vol.179 , pp. 739-743
    • Re, F.1    Muzio, M.2    De Rossi, M.3
  • 88
    • 0030096171 scopus 로고    scopus 로고
    • Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells
    • Levine SJ, Logun C, Chopra DP, Rhim JS, Shelhamer JH. Protein kinase C, interleukin-1 beta, and corticosteroids regulate shedding of the type I, 55 kDa TNF receptor from human airway epithelial cells. Am J Respir Cell Mol Biol 1996; 14: 254-261.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 254-261
    • Levine, S.J.1    Logun, C.2    Chopra, D.P.3    Rhim, J.S.4    Shelhamer, J.H.5
  • 90
    • 0025343696 scopus 로고
    • Glucocorticoid up-regulation of high-affinity interleukin 6 receptors on human epithelial cells
    • Snyers L, De Wit L, Content J. Glucocorticoid up-regulation of high-affinity interleukin 6 receptors on human epithelial cells. Proc Natl Acad Sci USA 1990; 87: 2838-2842.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2838-2842
    • Snyers, L.1    De Wit, L.2    Content, J.3
  • 91
    • 0029984282 scopus 로고    scopus 로고
    • Interleukin 6-receptor expression on human bronchial epithelial cells: Regulation by IL-1 and IL-6
    • Takizawa H, Ohtoshi T, Yamashita N, Oka T, Ito K. Interleukin 6-receptor expression on human bronchial epithelial cells: regulation by IL-1 and IL-6. Am J Physiol 1996; 270: L346-L352.
    • (1996) Am J Physiol , vol.270
    • Takizawa, H.1    Ohtoshi, T.2    Yamashita, N.3    Oka, T.4    Ito, K.5
  • 92
  • 93
    • 0028022515 scopus 로고
    • Expression of inducible nitric oxide in human lung epithelial cells
    • Robbins RA, Barnes PJ, Springall DR, et al. Expression of inducible nitric oxide in human lung epithelial cells. Biochem Biophys Res Commun 1994; 203: 209-218.
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 209-218
    • Robbins, R.A.1    Barnes, P.J.2    Springall, D.R.3
  • 94
    • 0029821696 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells
    • Berkman N, Robichaud A, Robbins RA, et al. Inhibition of inducible nitric oxide synthase expression by interleukin-4 and interleukin-13 in human lung epithelial cells. Immunology 1996; 89: 363-367.
    • (1996) Immunology , vol.89 , pp. 363-367
    • Berkman, N.1    Robichaud, A.2    Robbins, R.A.3
  • 95
    • 0028238576 scopus 로고
    • Oxidative stress induces NF kappa B DNA binding and inducible NOS mRNA in human epithelial cells
    • Adcock IM, Brown CR, Kwon O, Barnes PJ. Oxidative stress induces NF kappa B DNA binding and inducible NOS mRNA in human epithelial cells. Biochem Biophys Res Commun 1994; 199: 1518-1524.
    • (1994) Biochem Biophys Res Commun , vol.199 , pp. 1518-1524
    • Adcock, I.M.1    Brown, C.R.2    Kwon, O.3    Barnes, P.J.4
  • 96
    • 0027939931 scopus 로고
    • Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase
    • Xie QW, Kashiwabara Y, Nathan C. Role of transcription factor NF-kappa B/Rel in induction of nitric oxide synthase. J Biol Clin 1994; 269: 4705-4708.
    • (1994) J Biol Clin , vol.269 , pp. 4705-4708
    • Xie, Q.W.1    Kashiwabara, Y.2    Nathan, C.3
  • 97
    • 0029561936 scopus 로고
    • Nitric oxide and asthma
    • Barnes PJ. Nitric oxide and asthma. Res Immunol 1995; 146: 698-702.
    • (1995) Res Immunol , vol.146 , pp. 698-702
    • Barnes, P.J.1
  • 98
    • 0025984463 scopus 로고
    • Cytokine- and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone
    • Schalkwijk C, Vervoordeldonk M, Pfeilschifter J, Marki F, van den Bosch H. Cytokine- and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone. Biochem Biophys Res Commun 1991; 180: 46-52.
    • (1991) Biochem Biophys Res Commun , vol.180 , pp. 46-52
    • Schalkwijk, C.1    Vervoordeldonk, M.2    Pfeilschifter, J.3    Marki, F.4    Van Den Bosch, H.5
  • 99
    • 0027942832 scopus 로고
    • Induction of cyclooxygenase-2 by cytokines in human pulmonary epithelial cells: Regulation by dexamethasone
    • Mitchell JA, Belvisi MG, Akarasereenont P, et al. Induction of cyclooxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone. Br J Pharmacol 1994; 113: 1008-1014.
    • (1994) Br J Pharmacol , vol.113 , pp. 1008-1014
    • Mitchell, J.A.1    Belvisi, M.G.2    Akarasereenont, P.3
  • 101
    • 0027453206 scopus 로고
    • Dexamethasone increases airway epithelial cell neutral endopeptidase by enhancing transcription and new protein synthesis
    • Lang Z, Murlas CG. Dexamethasone increases airway epithelial cell neutral endopeptidase by enhancing transcription and new protein synthesis. Lung 1993; 171: 161-172.
    • (1993) Lung , vol.171 , pp. 161-172
    • Lang, Z.1    Murlas, C.G.2
  • 102
    • 0026030485 scopus 로고
    • Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells
    • Borson DB, Gruenert DC. Glucocorticoids induce neutral endopeptidase in transformed human tracheal epithelial cells. Am J Physiol 1991; 260: L83-L89.
    • (1991) Am J Physiol , vol.260
    • Borson, D.B.1    Gruenert, D.C.2
  • 103
    • 0026093160 scopus 로고
    • Modulation of neurogenic inflammation by neutral endopeptidase
    • Nadel JA, Borson DB. Modulation of neurogenic inflammation by neutral endopeptidase. Am Rev Respir Dis 1991; 143: S33-S36.
    • (1991) Am Rev Respir Dis , vol.143
    • Nadel, J.A.1    Borson, D.B.2
  • 104
    • 0031134823 scopus 로고    scopus 로고
    • Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid- Versus nonsteroid-treated patients with atopic asthma
    • Sont JK, van Krieken JH, van Klink HC, et al. Enhanced expression of neutral endopeptidase (NEP) in airway epithelium in biopsies from steroid- versus nonsteroid-treated patients with atopic asthma. Am J Respir Cell Mol Biol 1997; 16: 549-556.
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 549-556
    • Sont, J.K.1    Van Krieken, J.H.2    Van Klink, H.C.3
  • 105
    • 0028221993 scopus 로고
    • Endothelins. Biochemistry and pathophysiologic actions
    • Gandhi CK, Berkowitz DE, Watkins WD. Endothelins. Biochemistry and pathophysiologic actions. Anesthesiology 1994; 80: 892-905.
    • (1994) Anesthesiology , vol.80 , pp. 892-905
    • Gandhi, C.K.1    Berkowitz, D.E.2    Watkins, W.D.3
  • 106
    • 0026447182 scopus 로고
    • Increased expression of endothelin in bronchial epithelial cells of asthmatic patients and effect of corticosteroids
    • Vittori E, Marini M, Fasoli A, De Franchis R, Mattoli S. Increased expression of endothelin in bronchial epithelial cells of asthmatic patients and effect of corticosteroids. Am Rev Respir Dis 1992; 146: 1320-1325.
    • (1992) Am Rev Respir Dis , vol.146 , pp. 1320-1325
    • Vittori, E.1    Marini, M.2    Fasoli, A.3    De Franchis, R.4    Mattoli, S.5
  • 107
    • 0027197749 scopus 로고
    • Endothelin-induced contraction and mediator release in human bronchus
    • Hay DW, Hubbard WC, Undem BJ. Endothelin-induced contraction and mediator release in human bronchus. Br J Pharmacol 1993; 110: 392-398.
    • (1993) Br J Pharmacol , vol.110 , pp. 392-398
    • Hay, D.W.1    Hubbard, W.C.2    Undem, B.J.3
  • 108
    • 0025469601 scopus 로고
    • Specific binding of endothelin on human bronchial smooth muscle cells in culture and secretion of endothelin-like material from bronchial epithelial cells
    • Mattoli S, Mezzetti M, Riva G, Allegra L, Fasoli A. Specific binding of endothelin on human bronchial smooth muscle cells in culture and secretion of endothelin-like material from bronchial epithelial cells. Am J Respir Cell Mol Biol 1990; 3: 145-151.
    • (1990) Am J Respir Cell Mol Biol , vol.3 , pp. 145-151
    • Mattoli, S.1    Mezzetti, M.2    Riva, G.3    Allegra, L.4    Fasoli, A.5
  • 109
    • 0028145990 scopus 로고
    • Endothelins and pulmonary diseases
    • Barnes PJ. Endothelins and pulmonary diseases. J Appl Physiol 1994; 77: 1051-1059.
    • (1994) J Appl Physiol , vol.77 , pp. 1051-1059
    • Barnes, P.J.1
  • 110
    • 0028839144 scopus 로고
    • Endothelin induced collagen remodeling in experimental pulmonary hypertension
    • Mansoor AM, Honda M, Saida K, et al. Endothelin induced collagen remodeling in experimental pulmonary hypertension. Biochem Biophys Res Commun 1995; 215: 981-986.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 981-986
    • Mansoor, A.M.1    Honda, M.2    Saida, K.3
  • 111
    • 0029966017 scopus 로고    scopus 로고
    • The effects of endothelin-1 on collagen type I and type III synthesis in cultured porcine coronary artery vascular smooth muscle cells
    • Rizvi MA, Katwa L. Spadone DP, Myers PR. The effects of endothelin-1 on collagen type I and type III synthesis in cultured porcine coronary artery vascular smooth muscle cells. J Mol Cell Biol 1996; 28: 243-252.
    • (1996) J Mol Cell Biol , vol.28 , pp. 243-252
    • Rizvi, M.A.1    Katwa, L.2    Spadone, D.P.3    Myers, P.R.4
  • 112
    • 0030025731 scopus 로고    scopus 로고
    • Changes in collagen metabolism in response to endothelin-1: Evidence for fibroblast heterogeneity
    • Dawes KE, Cambrey AD, Campa JS, et al. Changes in collagen metabolism in response to endothelin-1: evidence for fibroblast heterogeneity. Int J Biochem Cell Biol 1996; 28: 229-238.
    • (1996) Int J Biochem Cell Biol , vol.28 , pp. 229-238
    • Dawes, K.E.1    Cambrey, A.D.2    Campa, J.S.3
  • 114
    • 0030828035 scopus 로고    scopus 로고
    • Immunoreactive endothelin in bronchial biopsy specimens: Increased expression in asthma and modulation by corticosteroid therapy
    • Redington AE, Springall DR, Meng QH, et al. Immunoreactive endothelin in bronchial biopsy specimens: increased expression in asthma and modulation by corticosteroid therapy. J Allergy Clin Immunol 1997; 100: 544-552.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 544-552
    • Redington, A.E.1    Springall, D.R.2    Meng, Q.H.3
  • 115
    • 0030828035 scopus 로고    scopus 로고
    • Immunoreactive endothelin in bronchial biopsy specimens increased expression in asthma and modulation by corticosteroid therapy
    • Redington AE, Springall DR, Meng QH, et al. Immunoreactive endothelin in bronchial biopsy specimens increased expression in asthma and modulation by corticosteroid therapy. J Allergy Clin Immunol 1997; 100: 544-552.
    • (1997) J Allergy Clin Immunol , vol.100 , pp. 544-552
    • Redington, A.E.1    Springall, D.R.2    Meng, Q.H.3
  • 116
    • 0026470092 scopus 로고
    • A mechanism for the antiinflammatory effects of corticosteroids: The glucocurticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1
    • Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: the glucocurticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1992; 89: 9991-9995.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 9991-9995
    • Cronstein, B.N.1    Kimmel, S.C.2    Levin, R.I.3    Martiniuk, F.4    Weissmann, G.5
  • 117
    • 0027564905 scopus 로고
    • Glucocorticoid-mediated repression of intercellular adhesion molecule-1 expression in human monocytic and bronchial epithelial cell lines
    • van de Stolpe A, Caldenhoven E, Raaijmakers JA, van der Saag PT, Koenderman L. Glucocorticoid-mediated repression of intercellular adhesion molecule-1 expression in human monocytic and bronchial epithelial cell lines. Am J Respir Cell Mol Biol 1993; 8: 340-347.
    • (1993) Am J Respir Cell Mol Biol , vol.8 , pp. 340-347
    • Van De Stolpe, A.1    Caldenhoven, E.2    Raaijmakers, J.A.3    Van Der Saag, P.T.4    Koenderman, L.5
  • 118
    • 0030767066 scopus 로고    scopus 로고
    • Inhibition of adhesion molecules by budesonide on a human epithelial cell line (lung carcinoma)
    • Paolieri F, Battifora M, Riccio AM, et al. Inhibition of adhesion molecules by budesonide on a human epithelial cell line (lung carcinoma). Allergy 1997; 52: 935-943.
    • (1997) Allergy , vol.52 , pp. 935-943
    • Paolieri, F.1    Battifora, M.2    Riccio, A.M.3
  • 119
    • 0026667153 scopus 로고
    • The bronchial epithelium as a target for inflammatory attack in asthma
    • Montefort S, Herbert CA, Robinson C, Holgate ST. The bronchial epithelium as a target for inflammatory attack in asthma. [Review]. Clin Exp Allergy 1992; 22: 511-520.
    • (1992) Clin Exp Allergy , vol.22 , pp. 511-520
    • Montefort, S.1    Herbert, C.A.2    Robinson, C.3    Holgate, S.T.4
  • 120
    • 8244258021 scopus 로고    scopus 로고
    • Eosinophil adhesion to human bronchial epithelial cells: Regulation by cytokines
    • Sato M, Takizawa H, Kohyama T, et al. Eosinophil adhesion to human bronchial epithelial cells: regulation by cytokines. Int Arch Allergy Immunol 1997; 113: 203-205.
    • (1997) Int Arch Allergy Immunol , vol.113 , pp. 203-205
    • Sato, M.1    Takizawa, H.2    Kohyama, T.3
  • 121
    • 0026764032 scopus 로고
    • Regulation of inflammation by lipocortin 1
    • Goulding NJ, Guyre PM. Regulation of inflammation by lipocortin 1. Immunol Today 1992; 13: 295-297.
    • (1992) Immunol Today , vol.13 , pp. 295-297
    • Goulding, N.J.1    Guyre, P.M.2
  • 122
    • 0023321841 scopus 로고
    • Annexins-new family of Ca2+-regulated-phospholipid binding protein
    • Geisow MJ, Walker JH, Boustead C, Taylor W. Annexins-new family of Ca2+-regulated-phospholipid binding protein. Biosci Rep 1987; 7: 289-298.
    • (1987) Biosci Rep , vol.7 , pp. 289-298
    • Geisow, M.J.1    Walker, J.H.2    Boustead, C.3    Taylor, W.4
  • 123
    • 0023751736 scopus 로고
    • Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids
    • Flower RJ. Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids. Br J Pharmacol 1988; 94: 987-1015.
    • (1988) Br J Pharmacol , vol.94 , pp. 987-1015
    • Flower, R.J.1
  • 124
    • 0022639806 scopus 로고
    • Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential antiinflammatory activity
    • Wallner BP, Mattaliano RJ, Hession C, et al. Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential antiinflammatory activity. Nature 1986; 320: 77-81.
    • (1986) Nature , vol.320 , pp. 77-81
    • Wallner, B.P.1    Mattaliano, R.J.2    Hession, C.3
  • 125
    • 0029889007 scopus 로고    scopus 로고
    • Expression of lipocortins in human bronchial epithelial cells: Effects of IL-1B, TNF-a, LPS and dexamethasone
    • Verheggen MM, De Bont HI. Adriaansen-Soeting PWC, et al. Expression of lipocortins in human bronchial epithelial cells: effects of IL-1B, TNF-a, LPS and dexamethasone. Med Inflam 1996; 5: 210-217.
    • (1996) Med Inflam , vol.5 , pp. 210-217
    • Verheggen, M.M.1    De Bont, H.I.2    Adriaansen-Soeting, P.W.C.3
  • 126
    • 0029769298 scopus 로고    scopus 로고
    • Eicosanoids and lipocortin-1 in BAL fluid in asthma: Effects of smoking and inhaled g glucocorticoids
    • van Hal PT, Overbeek SE, Hoogsteden HC, et al. Eicosanoids and lipocortin-1 in BAL fluid in asthma: effects of smoking and inhaled g glucocorticoids. J Appl Physiol 1996; 81: 548-555.
    • (1996) J Appl Physiol , vol.81 , pp. 548-555
    • Van Hal, P.T.1    Overbeek, S.E.2    Hoogsteden, H.C.3
  • 127
    • 0030211190 scopus 로고    scopus 로고
    • Corticosteroids induce intracellular interleukin-1 receptor antagonist type I expression by a human airway epithelial cell line
    • Levine SJ, Benfield T, Shelhamer JH. Corticosteroids induce intracellular interleukin-1 receptor antagonist type I expression by a human airway epithelial cell line. Am J Respir Cell Mol Biol 1996; 15: 245-251.
    • (1996) Am J Respir Cell Mol Biol , vol.15 , pp. 245-251
    • Levine, S.J.1    Benfield, T.2    Shelhamer, J.H.3
  • 128
    • 0028925985 scopus 로고
    • Corticosteroids increase secretory leukocyte protease inhibitor transcript levels in airway epithelial cells
    • Abbinante-Nissen JM, Simpson LG, Leikauf GD. Corticosteroids increase secretory leukocyte protease inhibitor transcript levels in airway epithelial cells. Am J Physiol 1995; 268: L601-L606.
    • (1995) Am J Physiol , vol.268
    • Abbinante-Nissen, J.M.1    Simpson, L.G.2    Leikauf, G.D.3
  • 129
    • 14444285040 scopus 로고    scopus 로고
    • The effect of treatment with oral corticosteroids on asthma symptoms and airway inflammation
    • Djukanovic R, Homeyard S, Gratziou C, et al. The effect of treatment with oral corticosteroids on asthma symptoms and airway inflammation. Am J Respir Crit Care Med 1997; 155: 826-832.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 826-832
    • Djukanovic, R.1    Homeyard, S.2    Gratziou, C.3
  • 130
    • 0030934422 scopus 로고    scopus 로고
    • Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy
    • Naseer T, Minshall EM, Leung DY, et al. Expression of IL-12 and IL-13 mRNA in asthma and their modulation in response to steroid therapy. Am J Respir Crit Care Med 1997; 155: 845-851.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 845-851
    • Naseer, T.1    Minshall, E.M.2    Leung, D.Y.3
  • 131
    • 0027320031 scopus 로고
    • Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma
    • Robinson D, Hamid Q, Bentley A, Ying S, Kay AB, Durham SR. Activation of CD4+ T cells, increased TH2-type cytokine mRNA expression, and eosinophil recruitment in bronchoalveolar lavage after allergen inhalation challenge in patients with atopic asthma. J Allergy Clin Immunol 1993; 92: 313-324.
    • (1993) J Allergy Clin Immunol , vol.92 , pp. 313-324
    • Robinson, D.1    Hamid, Q.2    Bentley, A.3    Ying, S.4    Kay, A.B.5    Durham, S.R.6
  • 132
    • 0030048946 scopus 로고    scopus 로고
    • Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
    • Bentley AM, Hamid Q, Robinson DS, et al. Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am J Respir Crit Care Med 1996; 153: 551-556.
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 551-556
    • Bentley, A.M.1    Hamid, Q.2    Robinson, D.S.3
  • 133
    • 0026590451 scopus 로고
    • Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma
    • Djukanovic R, Wilson JW, Britten KM, et al. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis 1992; 145: 669-674.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 669-674
    • Djukanovic, R.1    Wilson, J.W.2    Britten, K.M.3
  • 135
    • 0030958324 scopus 로고    scopus 로고
    • Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: A placebo-controlled study
    • Olivieri D, Chetta A, Del Donno M, et al. Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: a placebo-controlled study. Am J Respir Crit Care Med 1997; 155: 1864-1871.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1864-1871
    • Olivieri, D.1    Chetta, A.2    Del Donno, M.3
  • 136
    • 0027252871 scopus 로고
    • Changes in bronchoalveolar lavage inflammatory cells in asthmatic patients treated with high dose inhaled beclomethasone dipropionate
    • Duddridge M, Ward C, Hendrick DJ, Walters EH. Changes in bronchoalveolar lavage inflammatory cells in asthmatic patients treated with high dose inhaled beclomethasone dipropionate. Eur Respir J 1993; 6: 489-497.
    • (1993) Eur Respir J , vol.6 , pp. 489-497
    • Duddridge, M.1    Ward, C.2    Hendrick, D.J.3    Walters, E.H.4
  • 137
    • 0020512598 scopus 로고
    • Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells
    • Schleimer RP, Schulman EN, MacGlashan DW Jr, et al. Effects of dexamethasone on mediator release from human lung fragments and purified human lung mast cells. J Clin Invest 1983; 71: 1830-1835.
    • (1983) J Clin Invest , vol.71 , pp. 1830-1835
    • Schleimer, R.P.1    Schulman, E.N.2    MacGlashan Jr., D.W.3
  • 138
    • 0025067444 scopus 로고
    • Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma
    • Schleimer RP. Effects of glucocorticosteroids on inflammatory cells relevant to their therapeutic applications in asthma. Am Rev Respir Dis 1990; 141: S59-S69.
    • (1990) Am Rev Respir Dis , vol.141
    • Schleimer, R.P.1
  • 139
    • 0023720148 scopus 로고
    • T-cell antigen receptor genes and T-cell recognition
    • Davis MM, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334: 395-402.
    • (1988) Nature , vol.334 , pp. 395-402
    • Davis, M.M.1    Bjorkman, P.J.2
  • 140
    • 0021719897 scopus 로고
    • Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release
    • Inaba K, Steinman RM. Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen-presenting cell) requirements for growth and lymphokine release. J Exp Med 1984; 160: 1717-1735.
    • (1984) J Exp Med , vol.160 , pp. 1717-1735
    • Inaba, K.1    Steinman, R.M.2
  • 141
    • 0029927257 scopus 로고    scopus 로고
    • Increased number of dendritic cells in the bronchial mucosa of atopic asthmatics: Downregulation by inhaled corticosteroids
    • Möller GM, Overbeek SE, van Helden-Meeuwsen CG, et al. Increased number of dendritic cells in the bronchial mucosa of atopic asthmatics: downregulation by inhaled corticosteroids. Clin Exp Allergy 1996; 26: 517-524.
    • (1996) Clin Exp Allergy , vol.26 , pp. 517-524
    • Möller, G.M.1    Overbeek, S.E.2    Van Helden-Meeuwsen, C.G.3
  • 142
    • 0025037094 scopus 로고
    • Eosinophilic inflammation in asthma
    • Bousquet J, Chanez P, Lacoste JY, et al. eosinophilic inflammation in asthma. N Engl J Med 1990; 323: 1033-1039.
    • (1990) N Engl J Med , vol.323 , pp. 1033-1039
    • Bousquet, J.1    Chanez, P.2    Lacoste, J.Y.3
  • 143
    • 0023203720 scopus 로고
    • The role of the eosinophil in the pathogenesis of asthma
    • Wardlaw AJ, Kay AB. The role of the eosinophil in the pathogenesis of asthma. Allergy 1987; 42: 321-335.
    • (1987) Allergy , vol.42 , pp. 321-335
    • Wardlaw, A.J.1    Kay, A.B.2
  • 144
    • 0024996772 scopus 로고
    • Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry
    • Djukanovic R, Wilson JW, Britten KM, et al. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am Rev Respir Dis 1990; 142: 863-871.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 863-871
    • Djukanovic, R.1    Wilson, J.W.2    Britten, K.M.3
  • 146
    • 0025611180 scopus 로고
    • Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma
    • Azzawi M, Bradley B, Jeffery PK, et al. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am Rev Respir Dis 1990; 142: 1407-1413.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 1407-1413
    • Azzawi, M.1    Bradley, B.2    Jeffery, P.K.3
  • 147
    • 0024545977 scopus 로고
    • Cellular events in the bronchi in mild asthma and after bronchial provocation
    • Beasley R, Roche WR, Roberts JA, Holgate ST. Cellular events in the bronchi in mild asthma and after bronchial provocation. Am Rev Respir Dis 1989; 139: 806-817.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 806-817
    • Beasley, R.1    Roche, W.R.2    Roberts, J.A.3    Holgate, S.T.4
  • 148
    • 0025374344 scopus 로고
    • Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline
    • Adelroth E, Rosenhall L, Johansson SA, Linden M, Venge P. Inflammatory cells and eosinophilic activity in asthmatics investigated by bronchoalveolar lavage. The effects of antiasthmatic treatment with budesonide or terbutaline. Am Rev Respir Dis 1990; 142: 91-99.
    • (1990) Am Rev Respir Dis , vol.142 , pp. 91-99
    • Adelroth, E.1    Rosenhall, L.2    Johansson, S.A.3    Linden, M.4    Venge, P.5
  • 149
    • 0023034808 scopus 로고
    • Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival
    • Lopez AF, Williamson DJ, Gamble JR, et al. Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. J Clin Invest 1986; 78: 1220-1228.
    • (1986) J Clin Invest , vol.78 , pp. 1220-1228
    • Lopez, A.F.1    Williamson, D.J.2    Gamble, J.R.3
  • 150
    • 0024356310 scopus 로고
    • Interleukin 5 and phenotypically altered eosinophils in the blood of patients with the idiopathic hypereosinophilic syndrome
    • Owen WF, Rothenberg ME, Petersen J, et al. Interleukin 5 and phenotypically altered eosinophils in the blood of patients with the idiopathic hypereosinophilic syndrome. J Exp Med 1989; 170: 343-348.
    • (1989) J Exp Med , vol.170 , pp. 343-348
    • Owen, W.F.1    Rothenberg, M.E.2    Petersen, J.3
  • 151
    • 0023882364 scopus 로고
    • Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3
    • Rothenberg ME, Owen WF Jr, Silberstein DS, et al. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest 1988; 81: 1986-1992.
    • (1988) J Clin Invest , vol.81 , pp. 1986-1992
    • Rothenberg, M.E.1    Owen Jr., W.F.2    Silberstein, D.S.3
  • 152
    • 0024591512 scopus 로고
    • Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6, and GMCSF
    • Clutterbuck EJ, Hirst EM, Sanderson CJ. Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: comparison and interaction with IL-1, IL-3, IL-6, and GMCSF. Blood 1989; 73: 1504-1512.
    • (1989) Blood , vol.73 , pp. 1504-1512
    • Clutterbuck, E.J.1    Hirst, E.M.2    Sanderson, C.J.3
  • 153
    • 0030294075 scopus 로고    scopus 로고
    • Upregulatory effects of interleukin-4 and interleukin-13 but not interleukin-10 on granulocyte/ macrophage colony-stimulating factor production by human bronchial epithelial cells
    • Nakamura Y, Azuma M, Okano Y, et al. Upregulatory effects of interleukin-4 and interleukin-13 but not interleukin-10 on granulocyte/ macrophage colony-stimulating factor production by human bronchial epithelial cells. Am J Respir Cell Mol Biol 1996; 15: 680-687.
    • (1996) Am J Respir Cell Mol Biol , vol.15 , pp. 680-687
    • Nakamura, Y.1    Azuma, M.2    Okano, Y.3
  • 154
    • 0028844678 scopus 로고
    • Eosinophil cationic protein (ECP) and eosinophil protein X (EPX) concentrations in serum and bronchial lavage fluid in asthma. Effect of prednisolone treatment
    • Robinson DS, Assoufi B, Durham SR, Kay AB. Eosinophil cationic protein (ECP) and eosinophil protein X (EPX) concentrations in serum and bronchial lavage fluid in asthma. Effect of prednisolone treatment. Clin Exp Allergy 1995; 25: 1118-1127.
    • (1995) Clin Exp Allergy , vol.25 , pp. 1118-1127
    • Robinson, D.S.1    Assoufi, B.2    Durham, S.R.3    Kay, A.B.4
  • 155
    • 0026764094 scopus 로고
    • A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: A randomized, double-blind, parallel-group controlled trial
    • Laitinen IA, Laitinen A, Haahtela T. A comparative study of the effects of an inhaled corticosteroid, budesonide, and a beta 2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomized, double-blind, parallel-group controlled trial. J Allergy Clin Immunol 1992; 90; 32-42.
    • (1992) J Allergy Clin Immunol , vol.90 , pp. 32-42
    • Laitinen, I.A.1    Laitinen, A.2    Haahtela, T.3
  • 156
    • 0031045482 scopus 로고    scopus 로고
    • Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD
    • Keatings VM, Jatakanon A, Worsdell YM, Barnes PJ. Effects of inhaled and oral glucocorticoids on inflammatory indices in asthma and COPD. Am J Respir Crit Care Med 1997; 155: 542-548.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 542-548
    • Keatings, V.M.1    Jatakanon, A.2    Worsdell, Y.M.3    Barnes, P.J.4
  • 157
    • 0026540867 scopus 로고
    • Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma
    • Burke C, Power CK, Norris A, Condez A, Schmekel B, Poulter LW. Lung function and immunopathological changes after inhaled corticosteroid therapy in asthma. Eur Respir J 1992; 5: 73-79.
    • (1992) Eur Respir J , vol.5 , pp. 73-79
    • Burke, C.1    Power, C.K.2    Norris, A.3    Condez, A.4    Schmekel, B.5    Poulter, L.W.6
  • 158
    • 0030117685 scopus 로고    scopus 로고
    • Glucocorticosteroids affect functions of airway- and blood-derived human T-cell clones, favoring the Th1 profile through two mechanisms
    • Krouwels FH, van der Heijden JF, Lutter R, van Neerven RJ, Jansen HM, Out TA. Glucocorticosteroids affect functions of airway- and blood-derived human T-cell clones, favoring the Th1 profile through two mechanisms. Am J Respir Cell Mol Biol 1996; 14: 388-397.
    • (1996) Am J Respir Cell Mol Biol , vol.14 , pp. 388-397
    • Krouwels, F.H.1    Van Der Heijden, J.F.2    Lutter, R.3    Van Neerven, R.J.4    Jansen, H.M.5    Out, T.A.6
  • 159
    • 0017729257 scopus 로고
    • Scanning electron microscopic studies of bronchial mucosa before and during treatment with beclomethasone dipropionate inhalations
    • Lundgren R. Scanning electron microscopic studies of bronchial mucosa before and during treatment with beclomethasone dipropionate inhalations. Scand J Respir Dis Suppl 1977; 101: 179-187.
    • (1977) Scand J Respir Dis Suppl , vol.101 , pp. 179-187
    • Lundgren, R.1
  • 160
    • 0023871243 scopus 로고
    • Dexamethasone inhibits respiratory glycoconjugate secretion from feline airways in vitro by the induction of lipocortin (lipomodulin) synthesis
    • Lundgren JD, Hirata F, Marom Z, et al. Dexamethasone inhibits respiratory glycoconjugate secretion from feline airways in vitro by the induction of lipocortin (lipomodulin) synthesis. Am Rev Respir Dis 1988; 137: 353-357.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 353-357
    • Lundgren, J.D.1    Hirata, F.2    Marom, Z.3
  • 161
    • 0026606394 scopus 로고
    • Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study
    • Jeffery PK, Godfrey RW, Adelroth E, Nelson F, Rogers A, Johansson SA. Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma. A quantitative light and electron microscopic study. Am Rev Respir Dis 1992; 145: 890-899.
    • (1992) Am Rev Respir Dis , vol.145 , pp. 890-899
    • Jeffery, P.K.1    Godfrey, R.W.2    Adelroth, E.3    Nelson, F.4    Rogers, A.5    Johansson, S.A.6
  • 162
    • 0027377816 scopus 로고
    • An overview of glucocorticoid anti-inflammatory actions
    • Schleimer RP. An overview of glucocorticoid anti-inflammatory actions Eur J Clin Pharmacol 1993; 45: S3-S7.
    • (1993) Eur J Clin Pharmacol , vol.45
    • Schleimer, R.P.1
  • 163
    • 0026026861 scopus 로고
    • Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma. Effects of therapy with inhaled steroids
    • van de Graaf EA, Out TA, Roos CM, Jansen HM. Respiratory membrane permeability and bronchial hyperreactivity in patients with stable asthma. Effects of therapy with inhaled steroids. Am Rev Respir Dis 1991; 143: 362-368.
    • (1991) Am Rev Respir Dis , vol.143 , pp. 362-368
    • Van De Graaf, E.A.1    Out, T.A.2    Roos, C.M.3    Jansen, H.M.4
  • 164
    • 0022970690 scopus 로고
    • Anti-asthma drugs attenuate inflammatory-leakage of plasma into airway lumen
    • Erjefalt I, Persson CG. Anti-asthma drugs attenuate inflammatory-leakage of plasma into airway lumen. Acta Physiol Scand 1986; 128: 653-654.
    • (1986) Acta Physiol Scand , vol.128 , pp. 653-654
    • Erjefalt, I.1    Persson, C.G.2
  • 166
    • 0025234961 scopus 로고
    • Direct inhibitory action of glucocorticoid on glycoconjugate secretion from airway submucosal glands
    • Shimura S, Sasaki T, Ikeda K, Yamauchi K, Sasaki H, Takishima T. Direct inhibitory action of glucocorticoid on glycoconjugate secretion from airway submucosal glands. Am Rev Respir Dis 1990; 141: 1044-1049.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 1044-1049
    • Shimura, S.1    Sasaki, T.2    Ikeda, K.3    Yamauchi, K.4    Sasaki, H.5    Takishima, T.6
  • 167
    • 9844250203 scopus 로고    scopus 로고
    • Effect of 1 year daily treatment with 400 microg budesonide (Pulmicort Turbuhaler) in newly diagnosed asthmatics
    • Osterman K, Carlholm M, Ekelund J, et al. Effect of 1 year daily treatment with 400 microg budesonide (Pulmicort Turbuhaler) in newly diagnosed asthmatics. Eur Respir J 1997; 10: 2210-2215.
    • (1997) Eur Respir J , vol.10 , pp. 2210-2215
    • Osterman, K.1    Carlholm, M.2    Ekelund, J.3
  • 168
    • 0030725172 scopus 로고    scopus 로고
    • A comparison of beclomethasone, salmeterol, and placebo in children with asthma
    • Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group
    • Simons FE. A comparison of beclomethasone, salmeterol, and placebo in children with asthma. Canadian Beclomethasone Dipropionate-Salmeterol Xinafoate Study Group. N Engl J Med 1997; 337: 1659-1665.
    • (1997) N Engl J Med , vol.337 , pp. 1659-1665
    • Simons, F.E.1
  • 169
    • 0025073318 scopus 로고
    • Effect of corticosteroids on airway hyperresponsiveness
    • Barnes PJ. Effect of corticosteroids on airway hyperresponsiveness. Am Rev Respir Dis 1990; 141: S70-S76.
    • (1990) Am Rev Respir Dis , vol.141
    • Barnes, P.J.1
  • 170
    • 0023217634 scopus 로고
    • Comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine
    • Cockcroft DW, Murdock KY. comparative effects of inhaled salbutamol, sodium cromoglycate, and beclomethasone dipropionate on allergen-induced early asthmatic responses, late asthmatic responses, and increased bronchial responsiveness to histamine. J Allergy Clin Immunol 1987; 79: 734-740.
    • (1987) J Allergy Clin Immunol , vol.79 , pp. 734-740
    • Cockcroft, D.W.1    Murdock, K.Y.2
  • 171
    • 0020438738 scopus 로고
    • Importance of duration of treatment with inhaled budesonide on the immediate and late bronchial reaction
    • Dahl R, Johansson SA. Importance of duration of treatment with inhaled budesonide on the immediate and late bronchial reaction. Eur J Respir Dis Suppl 1982; 122: 167-175.
    • (1982) Eur J Respir Dis Suppl , vol.122 , pp. 167-175
    • Dahl, R.1    Johansson, S.A.2
  • 172
    • 0020379111 scopus 로고
    • The effects of corticosteroids on the immediate asthmatic reaction
    • Burge PS. The effects of corticosteroids on the immediate asthmatic reaction. Eur J Respir Dis Suppl 1982; 122: 163-166.
    • (1982) Eur J Respir Dis Suppl , vol.122 , pp. 163-166
    • Burge, P.S.1
  • 173
    • 0018828638 scopus 로고
    • Effects of theophylline, terbutaline, and prednisone on antigen-induced bronchospasm and mediator release
    • Martin GL, Atkins PC, Dunsky EH, Zweiman B. Effects of theophylline, terbutaline, and prednisone on antigen-induced bronchospasm and mediator release. J Allergy Clin Immunol 1980; 66: 204-212.
    • (1980) J Allergy Clin Immunol , vol.66 , pp. 204-212
    • Martin, G.L.1    Atkins, P.C.2    Dunsky, E.H.3    Zweiman, B.4


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