-
1
-
-
0026590451
-
The effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma
-
Djukanović, R., J. W. Wilson, K. M. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. 1990. The effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am. Rev. Respir. Dis. 145:669-674.
-
(1990)
Am. Rev. Respir. Dis.
, vol.145
, pp. 669-674
-
-
Djukanović, R.1
Wilson, J.W.2
Britten, K.M.3
Wilson, S.J.4
Walls, A.F.5
Roche, W.R.6
Howarth, P.H.7
Holgate, S.T.8
-
2
-
-
0028154064
-
Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma
-
Wilson, J. W., R. Djukanović, P. H. Howarth, and S. T. Holgate. 1994. Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma. Am. J. Respir. Crit. Care Med. 149:86-90.
-
(1994)
Am. J. Respir. Crit. Care Med.
, vol.149
, pp. 86-90
-
-
Wilson, J.W.1
Djukanović, R.2
Howarth, P.H.3
Holgate, S.T.4
-
3
-
-
4243653819
-
The influence of inhaled fluticasone propionate on symptoms, pulmonary physiology, and airway inflammation in asthma
-
Montefort, S., I. Feather, J. Underwood, J. Madden, C. Porter, S. T. Holgate, and P. H. Howarth. 1995. The influence of inhaled fluticasone propionate on symptoms, pulmonary physiology, and airway inflammation in asthma (abstract). Am. J. Respir. Crit. Care Med. 151:40.
-
(1995)
Am. J. Respir. Crit. Care Med.
, vol.151
, pp. 40
-
-
Montefort, S.1
Feather, I.2
Underwood, J.3
Madden, J.4
Porter, C.5
Holgate, S.T.6
Howarth, P.H.7
-
4
-
-
0026764094
-
2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: A randomised double blind, parallel controlled trial
-
2-agonist, terbutaline, on airway inflammation in newly diagnosed asthma: a randomised double blind, parallel controlled trial. J. Allergy Clin. Immunol. 90:32-42.
-
(1992)
J. Allergy Clin. Immunol.
, vol.90
, pp. 32-42
-
-
Laitinen, L.A.1
Laitinen, A.2
Haahtela, T.3
-
5
-
-
0027183057
-
Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5 and interferon-gamma cytokine gene expression
-
Robinson, D. S., Q. Hamid, S. Ying, A. M. Bentley, B. Assoufi, S. R. Durham, and A. B. Kay. 1993. Prednisolone treatment in asthma is associated with modulation of bronchoalveolar lavage cell interleukin-4, interleukin-5 and interferon-gamma cytokine gene expression. Am. Rev. Respir. Dis. 148:401-406.
-
(1993)
Am. Rev. Respir. Dis.
, vol.148
, pp. 401-406
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
Bentley, A.M.4
Assoufi, B.5
Durham, S.R.6
Kay, A.B.7
-
6
-
-
0030048946
-
Prednisolone treatment in asthma. Reduction in the numbers of eosinophils. T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa
-
Bentley, A. M., Q. Hamid, D. S. Robinson, E. Schotman, Q. Meng, B. Assoufi, A. B. Kay, and S. R. Durham. 1996. Prednisolone treatment in asthma. Reduction in the numbers of eosinophils. T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa. Am. J. Respir. Crit. Care Med. 153:551-556.
-
(1996)
Am. J. Respir. Crit. Care Med.
, vol.153
, pp. 551-556
-
-
Bentley, A.M.1
Hamid, Q.2
Robinson, D.S.3
Schotman, E.4
Meng, Q.5
Assoufi, B.6
Kay, A.B.7
Durham, S.R.8
-
7
-
-
1542514768
-
Guidelines for the management of asthma in adults. Statement by the research unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign
-
British Thoracic Society. 1990. Guidelines for the management of asthma in adults. Statement by the research unit of the Royal College of Physicians of London, King's Fund Centre, National Asthma Campaign. B.M.J. 142:434-457.
-
(1990)
B.M.J.
, vol.142
, pp. 434-457
-
-
-
8
-
-
0016747809
-
Standardization of bronchial inhalation challenge procedures
-
Chai, H., R. S. Fan, L. A. Frolich, D. A. Mathison, J. A. McLean, R. R. Rosenthal, A. L. Sheffer, S. L. Spector, and R. G. Townley. 1975. Standardization of bronchial inhalation challenge procedures. J. Allergy Clin. Immunol. 56:323-327.
-
(1975)
J. Allergy Clin. Immunol.
, vol.56
, pp. 323-327
-
-
Chai, H.1
Fan, R.S.2
Frolich, L.A.3
Mathison, D.A.4
McLean, J.A.5
Rosenthal, R.R.6
Sheffer, A.L.7
Spector, S.L.8
Townley, R.G.9
-
9
-
-
0026033668
-
The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma
-
Djukanović, R., J. W. Wilson, C. K. W. Lai, S. T. Holgate, and P. H. Howarth. 1991. The safety aspects of fiberoptic bronchoscopy, bronchoalveolar lavage, and endobronchial biopsy in asthma. Am. Rev. Respir. Dis. 143:772-777.
-
(1991)
Am. Rev. Respir. Dis.
, vol.143
, pp. 772-777
-
-
Djukanović, R.1
Wilson, J.W.2
Lai, C.K.W.3
Holgate, S.T.4
Howarth, P.H.5
-
10
-
-
0028432821
-
Interleukins (IL)-4, -5, -6, and TNFα in normal and asthmatic airways: Evidence for the human mast cell as an important source of these cytokines
-
Bradding, P., J. A. Roberts, K. M. Britten, S. Montefort, R. Djukanović, P. H. Howarth, and S. T. Holgate. 1994. interleukins (IL)-4, -5, -6, and TNFα in normal and asthmatic airways: evidence for the human mast cell as an important source of these cytokines. Am. J. Respir. Cell Mol. Biol. 10:471-480.
-
(1994)
Am. J. Respir. Cell Mol. Biol.
, vol.10
, pp. 471-480
-
-
Bradding, P.1
Roberts, J.A.2
Britten, K.M.3
Montefort, S.4
Djukanović, R.5
Howarth, P.H.6
Holgate, S.T.7
-
11
-
-
0024996772
-
Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry
-
Djukanović, R., J. W. Wilson, K. W. Britten, S. J. Wilson, A. F. Walls, W. R. Roche, P. H. Howarth, and S. T. Holgate. 1990. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am. Rev. Respir. Dis. 142:863-871.
-
(1990)
Am. Rev. Respir. Dis.
, vol.142
, pp. 863-871
-
-
Djukanović, R.1
Wilson, J.W.2
Britten, K.W.3
Wilson, S.J.4
Walls, A.F.5
Roche, W.R.6
Howarth, P.H.7
Holgate, S.T.8
-
12
-
-
0025971576
-
Corticosteroid inhibition of airways microvascular leakage
-
Boschetto, P., D. F. Rogers, L. M. Fabbri, and P. J. Barnes. 1991. Corticosteroid inhibition of airways microvascular leakage. Am. Rev. Respir. Dis. 143:605-609.
-
(1991)
Am. Rev. Respir. Dis.
, vol.143
, pp. 605-609
-
-
Boschetto, P.1
Rogers, D.F.2
Fabbri, L.M.3
Barnes, P.J.4
-
13
-
-
0025234961
-
Direct inhibitory action of glucocorticoids on glycoconjugate secretion from airway submucosal glands
-
Shimura, S., T. Sasaki, K. Ikeda, K. Yamauchi, H. Sasaki, and T. Takishima. 1990. Direct inhibitory action of glucocorticoids on glycoconjugate secretion from airway submucosal glands. Am. Rev. Respir. Dis. 141:1044-1099.
-
(1990)
Am. Rev. Respir. Dis.
, vol.141
, pp. 1044-1099
-
-
Shimura, S.1
Sasaki, T.2
Ikeda, K.3
Yamauchi, K.4
Sasaki, H.5
Takishima, T.6
-
14
-
-
0025221099
-
Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages
-
DiRosa, M., M. Radomski, R. Carnuccio, and S. Moncada. 1990. Glucocorticoids inhibit the induction of nitric oxide synthase in macrophages. Biochem. Biophys. Res. Commun. 172:1246-1252.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.172
, pp. 1246-1252
-
-
DiRosa, M.1
Radomski, M.2
Carnuccio, R.3
Moncada, S.4
-
15
-
-
0020315133
-
Reversal of human lymphocyte beta-adrenoceptor desensitization by glucocorticoids
-
Hui, K. K., M. E. Conolly, and D. P. Tashkin. 1982. Reversal of human lymphocyte beta-adrenoceptor desensitization by glucocorticoids. Clin. Pharmacol. Ther. 32:566-571.
-
(1982)
Clin. Pharmacol. Ther.
, vol.32
, pp. 566-571
-
-
Hui, K.K.1
Conolly, M.E.2
Tashkin, D.P.3
-
16
-
-
0025324736
-
Mucosal inflammation in asthma
-
Djukanovic, R., W. R. Roche, J. S. Wilson, C. R. W. Beasley, O. P. Twentyman, and S. T. Holgate. 1990. Mucosal inflammation in asthma. Am. Rev. Respir. Dis. 142:434-457.
-
(1990)
Am. Rev. Respir. Dis.
, vol.142
, pp. 434-457
-
-
Djukanovic, R.1
Roche, W.R.2
Wilson, J.S.3
Beasley, C.R.W.4
Twentyman, O.P.5
Holgate, S.T.6
-
17
-
-
14444282143
-
Cellular composition of sputum induced by hypertonic saline in asthmatic and healthy subjects
-
Louis, R., L. Stanciu, J. Corne, P. Hurst, S. Biagi, F. Marelli, S. T. Holgate, and R. Djukanovic. 1995. Cellular composition of sputum induced by hypertonic saline in asthmatic and healthy subjects (abstract). Eur. Respir. J. 8:471.
-
(1995)
Eur. Respir. J.
, vol.8
, pp. 471
-
-
Louis, R.1
Stanciu, L.2
Corne, J.3
Hurst, P.4
Biagi, S.5
Marelli, F.6
Holgate, S.T.7
Djukanovic, R.8
-
18
-
-
0023831561
-
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity
-
Wardlaw, A. J., S. Dunnette, G. J. Gleich, J. V. Collins, and A. B. Kay. 1988. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma. Relationship to bronchial hyperreactivity. Am. Rev. Respir. Dis. 137:62-69.
-
(1988)
Am. Rev. Respir. Dis.
, vol.137
, pp. 62-69
-
-
Wardlaw, A.J.1
Dunnette, S.2
Gleich, G.J.3
Collins, J.V.4
Kay, A.B.5
-
19
-
-
0023554640
-
Bronchoalveolar cell profiles of asthmatic and nonasthmatic subjects
-
Kirby, J. G., F. E. Hargreave, G. J. Gleich, and P. M. O'Byrne. 1987. Bronchoalveolar cell profiles of asthmatic and nonasthmatic subjects. Am. Rev. Respir. Dis. 136:379-383.
-
(1987)
Am. Rev. Respir. Dis.
, vol.136
, pp. 379-383
-
-
Kirby, J.G.1
Hargreave, F.E.2
Gleich, G.J.3
O'Byrne, P.M.4
-
20
-
-
0018834859
-
Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium
-
Frigas, E., D. A. Loegering, and G. J. Gleich. 1980. Cytotoxic effects of the guinea pig eosinophil major basic protein on tracheal epithelium. Lab. Invest. 42:35-43.
-
(1980)
Lab. Invest.
, vol.42
, pp. 35-43
-
-
Frigas, E.1
Loegering, D.A.2
Gleich, G.J.3
-
21
-
-
0024010883
-
Effect of prednisone and beclomethasone dipropionate on airway responsiveness in asthma: A comparative study
-
Jenkins, C. R., and A. J. Woolcock. 1988. Effect of prednisone and beclomethasone dipropionate on airway responsiveness in asthma: a comparative study. Thorax 43:378-384.
-
(1988)
Thorax
, vol.43
, pp. 378-384
-
-
Jenkins, C.R.1
Woolcock, A.J.2
-
22
-
-
0025679065
-
First-time treatment with steroids in bronchial asthma: A comparison of the effects of inhaled beclomethasone and of oral prednisone on airway function, bronchial reactivity and hypothalamic-pituitary-adrenal axis
-
Wilmsmeyer, W., D. Ukena, T. O. F. Wagner, and G. W. Sybrecht. 1990. First-time treatment with steroids in bronchial asthma: a comparison of the effects of inhaled beclomethasone and of oral prednisone on airway function, bronchial reactivity and hypothalamic-pituitary-adrenal axis. Eur. Respir. J. 3:789-791.
-
(1990)
Eur. Respir. J.
, vol.3
, pp. 789-791
-
-
Wilmsmeyer, W.1
Ukena, D.2
Wagner, T.O.F.3
Sybrecht, G.W.4
-
23
-
-
0026075046
-
Glucocorticoids inhibit eosinophil responses togranulocyte-macrophage colony-stimulating factor
-
Lamas, A. M., O. G. Leon, and R. P. Schleimer. 1991. Glucocorticoids inhibit eosinophil responses togranulocyte-macrophage colony-stimulating factor. J. Immunol. 147:254-259.
-
(1991)
J. Immunol.
, vol.147
, pp. 254-259
-
-
Lamas, A.M.1
Leon, O.G.2
Schleimer, R.P.3
-
24
-
-
0025841768
-
Glucocorticoids inhibit cytokine-mediated eosinophil survival
-
Wallen, N., H. Kita, D. Weiler, and G. J. Gleich. 1991. Glucocorticoids inhibit cytokine-mediated eosinophil survival. J. Immunol. 147: 3490-3495.
-
(1991)
J. Immunol.
, vol.147
, pp. 3490-3495
-
-
Wallen, N.1
Kita, H.2
Weiler, D.3
Gleich, G.J.4
-
25
-
-
0023733822
-
Glucocorticoid effects on the production and action of immune cytokines
-
Guyre, P. M., M. T. Girard, P. M. Morganelli, and P. D. Manginiello. 1988. Glucocorticoid effects on the production and action of immune cytokines. J. Steroid Biochem. 30:89-93.
-
(1988)
J. Steroid Biochem.
, vol.30
, pp. 89-93
-
-
Guyre, P.M.1
Girard, M.T.2
Morganelli, P.M.3
Manginiello, P.D.4
-
26
-
-
0025944559
-
Glucocorticoids suppress the production of interleukin 4 by human lymphocytes
-
Wu, C. Y., C. Fargeas, T. Nakajima, and G. Delespesse. 1991. Glucocorticoids suppress the production of interleukin 4 by human lymphocytes. Eur. J. Immunol. 21:2645-2647.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2645-2647
-
-
Wu, C.Y.1
Fargeas, C.2
Nakajima, T.3
Delespesse, G.4
-
27
-
-
0026621211
-
Inhibition of interleukin-5 gene expression by dexamethasone
-
Rolfe, F. G., J. M. Hughes, C. L. Armour, and W. A. Sewell. 1992. Inhibition of interleukin-5 gene expression by dexamethasone. Immunology 77:494-499.
-
(1992)
Immunology
, vol.77
, pp. 494-499
-
-
Rolfe, F.G.1
Hughes, J.M.2
Armour, C.L.3
Sewell, W.A.4
-
28
-
-
0025611180
-
Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma
-
Azzawi, M., B. Bradley, P. K. Jeffery, A. J. Frew, A. J. Wardlaw, G. Knowles, B. Assoufi, J. V. Collins, S. R. Durham, and A. B. Kay. 1990. Identification of activated T lymphocytes and eosinophils in bronchial biopsies in stable atopic asthma. Am. Rev. Respir. Dis. 142:1407-1413.
-
(1990)
Am. Rev. Respir. Dis.
, vol.142
, pp. 1407-1413
-
-
Azzawi, M.1
Bradley, B.2
Jeffery, P.K.3
Frew, A.J.4
Wardlaw, A.J.5
Knowles, G.6
Assoufi, B.7
Collins, J.V.8
Durham, S.R.9
Kay, A.B.10
-
29
-
-
0029031677
-
Determinants of asthma severity
-
Djukanović, R., P. H. Howarth, B. Vrugt, S. Wilson, A. Semper, P. Bradding, R. Aalbers, and S. T. Holgate. 1995. Determinants of asthma severity. Int. Arch. Allergy Immunol. 107:389.
-
(1995)
Int. Arch. Allergy Immunol.
, vol.107
, pp. 389
-
-
Djukanović, R.1
Howarth, P.H.2
Vrugt, B.3
Wilson, S.4
Semper, A.5
Bradding, P.6
Aalbers, R.7
Holgate, S.T.8
-
30
-
-
0026333085
-
Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlates with disease severity
-
Walker, C., M. K. Kaegi, P. Braun, and K. Blaser. 1991. Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlates with disease severity. J. Allergy Clin. Immunol. 88:935-942.
-
(1991)
J. Allergy Clin. Immunol.
, vol.88
, pp. 935-942
-
-
Walker, C.1
Kaegi, M.K.2
Braun, P.3
Blaser, K.4
-
31
-
-
0026610142
-
Evidence for a predominant "Th2-type" bronchoalveolar lavage T lymphocyte population in atopic asthma
-
Robinson, D. S., Q. Hamid, S. Ying, A.Tsicopoulos, J. Barkans, A. M. Bentley, C. J. Corrigan, S. R. Durham, and A. B. Kay. 1992. Evidence for a predominant "Th2-type" bronchoalveolar lavage T lymphocyte population in atopic asthma. N. Engl. J. Med. 326:298-304.
-
(1992)
N. Engl. J. Med.
, vol.326
, pp. 298-304
-
-
Robinson, D.S.1
Hamid, Q.2
Ying, S.3
Tsicopoulos, A.4
Barkans, J.5
Bentley, A.M.6
Corrigan, C.J.7
Durham, S.R.8
Kay, A.B.9
-
32
-
-
0026586151
-
IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: Association with expression of VCAM-1
-
Schleimer, R. P., S. A. Sterbinsky, J. Kaiser, C. A. Bickel, D. A. Klunk, K. Tomioka, W. Newman, F. W. Luscinkas, M. A. Gimbrone, B. W. McIntyre, and B. S. Bochner. 1992. IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium: association with expression of VCAM-1. J. Immunol. 148:1086-1092.
-
(1992)
J. Immunol.
, vol.148
, pp. 1086-1092
-
-
Schleimer, R.P.1
Sterbinsky, S.A.2
Kaiser, J.3
Bickel, C.A.4
Klunk, D.A.5
Tomioka, K.6
Newman, W.7
Luscinkas, F.W.8
Gimbrone, M.A.9
McIntyre, B.W.10
Bochner, B.S.11
-
33
-
-
0020512598
-
Effects of dexamethasoneon mediator release from human fragments and purified human lung mast cells
-
Schleimer, R. P., E. S. Schulman, D. W. Macglashan, S. P. Peters, E. C. Hayes, G. K. Adams, L. M. Lichtenstein, and N. F. Adkinson, Jr. 1983. Effects of dexamethasoneon mediator release from human fragments and purified human lung mast cells. J. Clin. Invest. 71: 1830-1835.
-
(1983)
J. Clin. Invest.
, vol.71
, pp. 1830-1835
-
-
Schleimer, R.P.1
Schulman, E.S.2
Macglashan, D.W.3
Peters, S.P.4
Hayes, E.C.5
Adams, G.K.6
Lichtenstein, L.M.7
Adkinson Jr., N.F.8
-
34
-
-
0025877188
-
Effect of steroids on immunoglobulin-induced eosinophil degranulation
-
Kita, H., R. Abu-Ghazaleh, C. J. Sandreson, and G. J. Gleich. 1991. Effect of steroids on immunoglobulin-induced eosinophil degranulation. J. Allergy Clin. Immunol. 87:70-77.
-
(1991)
J. Allergy Clin. Immunol.
, vol.87
, pp. 70-77
-
-
Kita, H.1
Abu-Ghazaleh, R.2
Sandreson, C.J.3
Gleich, G.J.4
-
35
-
-
4243559603
-
Effect of corticosteroids on human eosinophils in vitro
-
Evans, P. M., P. J. Barnes, and K. F. Chung. 1990. Effect of corticosteroids on human eosinophils in vitro (abstract). Eur. J. Pharmacol. 3:160.
-
(1990)
Eur. J. Pharmacol.
, vol.3
, pp. 160
-
-
Evans, P.M.1
Barnes, P.J.2
Chung, K.F.3
-
36
-
-
0001660714
-
Glucocorticoids: Their mechanisms of action and use in allergic diseases
-
E. Middleton, Jr., C. E. Reed, E. F. Ellis, N. F. Adkinson, Jr., J. W. Yunginger, and W. W. Busse, editors, Mosby, St. Louis, MO
-
Schleimer, R. P., 1993. Glucocorticoids: their mechanisms of action and use in allergic diseases. In E. Middleton, Jr., C. E. Reed, E. F. Ellis, N. F. Adkinson, Jr., J. W. Yunginger, and W. W. Busse, editors, Allergy: Principles and Practice, 4th ed. Mosby, St. Louis, MO. 893-925.
-
(1993)
Allergy: Principles and Practice, 4th Ed.
, pp. 893-925
-
-
Schleimer, R.P.1
|