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Volumn 148, Issue 5, 1997, Pages 348-358

Role of T-cell anergy and suppression in susceptibility to IDDM

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE;

EID: 0030874898     PISSN: 09232494     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0923-2494(97)87245-8     Document Type: Article
Times cited : (15)

References (86)
  • 2
    • 0029785167 scopus 로고    scopus 로고
    • Interleukin-4: Potential immunoregulatory agent in therapy of insulin-dependent diabetes mellitus
    • Arreaza, G.A., Cameron, M.J. & Delovitch, T.L. (1996), Interleukin-4: Potential immunoregulatory agent in therapy of insulin-dependent diabetes mellitus. Clin. Immunother., 4, 251-260.
    • (1996) Clin. Immunother. , vol.4 , pp. 251-260
    • Arreaza, G.A.1    Cameron, M.J.2    Delovitch, T.L.3
  • 3
    • 85058206246 scopus 로고    scopus 로고
    • CD28 costimulation prevents insulin dependent diabetes by an IL-4 dependent mechanism in NOD mice
    • Arreaza, G.A., Cameron, M.J., Chakrabarti S. & Delovitch, T.L. (1997), CD28 costimulation prevents insulin dependent diabetes by an IL-4 dependent mechanism in NOD mice. J. Allergy Clin. Immunol., 99, S488.
    • (1997) J. Allergy Clin. Immunol. , vol.99
    • Arreaza, G.A.1    Cameron, M.J.2    Chakrabarti, S.3    Delovitch, T.L.4
  • 4
    • 0025472820 scopus 로고
    • Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy
    • Atkinson, M.A., MacLaren, N.K. & Luchetta, R. (1990), Insulitis and diabetes in NOD mice reduced by prophylactic insulin therapy. Diabetes, 39, 933-937.
    • (1990) Diabetes , vol.39 , pp. 933-937
    • Atkinson, M.A.1    Maclaren, N.K.2    Luchetta, R.3
  • 6
    • 0029942029 scopus 로고    scopus 로고
    • The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes
    • Balasa, B. & Sarvetnick, N. (1996), The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes. J. Autoimmun., 9, 283-286.
    • (1996) J. Autoimmun. , vol.9 , pp. 283-286
    • Balasa, B.1    Sarvetnick, N.2
  • 7
    • 0024434159 scopus 로고
    • Comparison of high-and low-diabetes-incidence NOD mouse strains
    • Baxter, A.G., Adams, M.A. & Mandel, T.E. (1989), Comparison of high-and low-diabetes-incidence NOD mouse strains. Diabetes, 38, 1296-1300.
    • (1989) Diabetes , vol.38 , pp. 1296-1300
    • Baxter, A.G.1    Adams, M.A.2    Mandel, T.E.3
  • 13
    • 0028979466 scopus 로고
    • New perspectives of CD28-B7-mediated T cell costimulation
    • Bluestone, J.A. (1995), New perspectives of CD28-B7-mediated T cell costimulation. Immunity, 2, 555-559.
    • (1995) Immunity , vol.2 , pp. 555-559
    • Bluestone, J.A.1
  • 15
    • 0024500755 scopus 로고
    • T cell mediated inhibition of the transfer of autoimmune diabetes in NOD mice
    • Boitard, C., Yasunami, R., Dardenne, M. & Bach, J.F. (1989), T cell mediated inhibition of the transfer of autoimmune diabetes in NOD mice. J. Exp. Med., 169, 1669-1680.
    • (1989) J. Exp. Med. , vol.169 , pp. 1669-1680
    • Boitard, C.1    Yasunami, R.2    Dardenne, M.3    Bach, J.F.4
  • 17
    • 0030050676 scopus 로고    scopus 로고
    • Immunological and metabolic effects of prophylactic insulin therapy in the NOD-scid/scid adoptive transfer model of IDDM
    • Bowman, M.A., Campbell, L., Darrow, B.L., Ellis, T.M., Suresh, A. & Atkinson, M.A. (1996), Immunological and metabolic effects of prophylactic insulin therapy in the NOD-scid/scid adoptive transfer model of IDDM. Diabetes, 45, 205-208.
    • (1996) Diabetes , vol.45 , pp. 205-208
    • Bowman, M.A.1    Campbell, L.2    Darrow, B.L.3    Ellis, T.M.4    Suresh, A.5    Atkinson, M.A.6
  • 18
    • 0026674336 scopus 로고
    • Absence of T cell tolerance to pancreatic islet cells
    • Burtles, S.S., Trembleau, S., Drexler, K. & Hurtenbach, U. (1992), Absence of T cell tolerance to pancreatic islet cells. J. Immunol., 149, 2185-2193.
    • (1992) J. Immunol. , vol.149 , pp. 2185-2193
    • Burtles, S.S.1    Trembleau, S.2    Drexler, K.3    Hurtenbach, U.4
  • 21
    • 0024563945 scopus 로고
    • Cyclophosphamide induced diabetes in NOD/Wehi mice: Evidence for suppression in spontaneous autoimmune diabetes mellitus
    • Charlton, B., Bacejl, A., Slattery, R.M. & Mandel, T.E. (1989), Cyclophosphamide induced diabetes in NOD/Wehi mice: evidence for suppression in spontaneous autoimmune diabetes mellitus. Diabetes, 38, 441-447.
    • (1989) Diabetes , vol.38 , pp. 441-447
    • Charlton, B.1    Bacejl, A.2    Slattery, R.M.3    Mandel, T.E.4
  • 22
    • 0027958044 scopus 로고
    • Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice
    • Chatenoud, L., Thervet, E., Primo, J. & Bach, J.F. (1994), Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice. Proc. Natl. Acad. Sci. USA, 91, 123-127.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 123-127
    • Chatenoud, L.1    Thervet, E.2    Primo, J.3    Bach, J.F.4
  • 23
    • 0031569177 scopus 로고    scopus 로고
    • CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice
    • Chatenoud, L., Primo, J. & Bach, J.F. (1997), CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J. Immunol., 158, 2947-2954.
    • (1997) J. Immunol. , vol.158 , pp. 2947-2954
    • Chatenoud, L.1    Primo, J.2    Bach, J.F.3
  • 26
    • 0028914351 scopus 로고
    • Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific t cell clones isolated from NOD mice
    • Daniel, D., Gill, R.G., Schloot, N. & Wegmann, D. (1995), Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice. Eur. J. Immunol., 25, 1056-1062.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1056-1062
    • Daniel, D.1    Gill, R.G.2    Schloot, N.3    Wegmann, D.4
  • 27
    • 0030069688 scopus 로고    scopus 로고
    • Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23)
    • Daniel, D. & Wegmann, D.R. (1996), Protection of nonobese diabetic mice from diabetes by intranasal or subcutaneous administration of insulin peptide B-(9-23). Proc. Natl. Acad. Sci. USA, 93, 956-960.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 956-960
    • Daniel, D.1    Wegmann, D.R.2
  • 30
    • 0026545730 scopus 로고
    • Intrathymic islet cell transplantation reduces β-cell autoimmunity and prevents diabetes in NOD/Lt mice
    • Gerling, I.C., Serreze, D.V., Christianson, S.W. & Leiter, E.H. (1992), Intrathymic islet cell transplantation reduces β-cell autoimmunity and prevents diabetes in NOD/Lt mice. Diabetes, 41, 1672-1676.
    • (1992) Diabetes , vol.41 , pp. 1672-1676
    • Gerling, I.C.1    Serreze, D.V.2    Christianson, S.W.3    Leiter, E.H.4
  • 31
    • 0027973197 scopus 로고
    • The thymus as a site for evaluating the potency of candidate beta cell autoantigens in NOD mice
    • Gerling, I.C., Atkinson, M.A. & Leiter, E.H. (1994), The thymus as a site for evaluating the potency of candidate beta cell autoantigens in NOD mice. J. Autoimmun., 7, 851-858.
    • (1994) J. Autoimmun. , vol.7 , pp. 851-858
    • Gerling, I.C.1    Atkinson, M.A.2    Leiter, E.H.3
  • 32
    • 0018949404 scopus 로고
    • The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease
    • Glimcher, L.H., Steinberg, A.D., House S.B. & Green, I. (1980), The autologous mixed lymphocyte reaction in strains of mice with autoimmune disease. J. Immunol., 125, 1832-1838.
    • (1980) J. Immunol. , vol.125 , pp. 1832-1838
    • Glimcher, L.H.1    Steinberg, A.D.2    House, S.B.3    Green, I.4
  • 35
    • 0030209820 scopus 로고    scopus 로고
    • Quantitative threshold of MHC class II I-E expressed on hematopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection
    • Hanson, M.S., Cetkovic-Cvrlje, M., Ramiya, V.K., Atkinson, M.A., MacLaren, N.K., Singh, B., Elliott, J.F., Serreze, D.V. & Leiter, E.H. (1996), Quantitative threshold of MHC class II I-E expressed on hematopoietically derived antigen-presenting cells in transgenic NOD/Lt mice determine level of diabetes resistance and indicate mechanism of protection. J. Immunol., 157, 1279-1287.
    • (1996) J. Immunol. , vol.157 , pp. 1279-1287
    • Hanson, M.S.1    Cetkovic-Cvrlje, M.2    Ramiya, V.K.3    Atkinson, M.A.4    Maclaren, N.K.5    Singh, B.6    Elliott, J.F.7    Serreze, D.V.8    Leiter, E.H.9
  • 36
    • 0030456670 scopus 로고    scopus 로고
    • Aerosol insulin induces regulatory CDS γδ T cells that prevent murine insulin-dependent diabetes
    • Harrison, L.C., Dempsey-Collier, M., Kramer, D.R. & Takahashi, K. (1996), Aerosol insulin induces regulatory CDS γδ T cells that prevent murine insulin-dependent diabetes. J. Exp. Med., 184, 2167-2174.
    • (1996) J. Exp. Med. , vol.184 , pp. 2167-2174
    • Harrison, L.C.1    Dempsey-Collier, M.2    Kramer, D.R.3    Takahashi, K.4
  • 38
    • 0026474808 scopus 로고
    • Expression of a tumor necrosis factor a transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes
    • Higuchi, Y., Herrera, P., Muniesa, P., Huarte, J., Belin, D., Ohashi, P., Aichele, P., Orci, L., Vassalli, J.D. & Vassalli, P. (1992), Expression of a tumor necrosis factor a transgene in murine pancreatic β cells results in severe and permanent insulitis without evolution towards diabetes. J. Exp. Med., 176, 1719-1731.
    • (1992) J. Exp. Med. , vol.176 , pp. 1719-1731
    • Higuchi, Y.1    Herrera, P.2    Muniesa, P.3    Huarte, J.4    Belin, D.5    Ohashi, P.6    Aichele, P.7    Orci, L.8    Vassalli, J.D.9    Vassalli, P.10
  • 39
    • 0025115596 scopus 로고
    • The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males
    • Hutchings, P.R. & Cooke A. (1990), The transfer of autoimmune diabetes in NOD mice can be inhibited or accelerated by distinct cell populations present in normal splenocytes taken from young males. J. Autoimmun., 3, 175-185.
    • (1990) J. Autoimmun. , vol.3 , pp. 175-185
    • Hutchings, P.R.1    Cooke, A.2
  • 40
    • 0028061186 scopus 로고
    • Insulin-dependent diabetes mellitus in the non-obese diabetic mouse: A disease mediated by T cell anergy?
    • Jaramillo, A., Gill, B.M. & Delovitch T.L. (1994), Insulin-dependent diabetes mellitus in the non-obese diabetic mouse: a disease mediated by T cell anergy? Life Sci., 55, 1163-77.
    • (1994) Life Sci. , vol.55 , pp. 1163-1177
    • Jaramillo, A.1    Gill, B.M.2    Delovitch, T.L.3
  • 42
    • 85030301181 scopus 로고    scopus 로고
    • "Forum in Immunology" (this issue)
    • Leiter, E.H., et al. (1997), in "Forum in Immunology". Res. Immunol., (this issue).
    • (1997) Res. Immunol.
    • Leiter, E.H.1
  • 46
    • 0343532107 scopus 로고
    • Cell lines and cytokine patterns of NOD mice orally fed with insulin b chain and schistosome egg antigen
    • oral communication. Orvieto, Italy
    • Maron, R., Hancock, W., Palanivel, V., Harn, D.A. & Weiner, H.L. (1995), Cell lines and cytokine patterns of NOD mice orally fed with insulin B chain and schistosome egg antigen, in "14th International Immunology and Diabetes Workshop" (oral communication). Orvieto, Italy.
    • (1995) 14th International Immunology and Diabetes Workshop
    • Maron, R.1    Hancock, W.2    Palanivel, V.3    Harn, D.A.4    Weiner, H.L.5
  • 47
    • 0024404932 scopus 로고
    • Distinction between immunogenicity and tolerogenicity among HBcAg T cell determinants, influence of peptide-MHC interaction
    • Milich, D.R., Jones, J.E., McLachlan, A., Houghton, R., Thornton, G.B. & Hughes, J.L. (1989), Distinction between immunogenicity and tolerogenicity among HBcAg T cell determinants, influence of peptide-MHC interaction. J. Immunol., 143, 3148-56.
    • (1989) J. Immunol. , vol.143 , pp. 3148-3156
    • Milich, D.R.1    Jones, J.E.2    McLachlan, A.3    Houghton, R.4    Thornton, G.B.5    Hughes, J.L.6
  • 48
    • 0028861576 scopus 로고
    • Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription
    • Muir, A., Peck, A., Clare-Salzler, M., Song, Y.H., Cornelius, J., Luchetta, R., Krischer, J. & MacLaren, N. (1995), Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-γ transcription. J. Clin. Invest., 95, 628-634.
    • (1995) J. Clin. Invest. , vol.95 , pp. 628-634
    • Muir, A.1    Peck, A.2    Clare-Salzler, M.3    Song, Y.H.4    Cornelius, J.5    Luchetta, R.6    Krischer, J.7    Maclaren, N.8
  • 49
    • 0029838995 scopus 로고    scopus 로고
    • Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice
    • Mueller, R., Krahl, T. & Sarvetnick, N. (1996), Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice. J. Exp. Med., 184, 1093-1099.
    • (1996) J. Exp. Med. , vol.184 , pp. 1093-1099
    • Mueller, R.1    Krahl, T.2    Sarvetnick, N.3
  • 50
    • 0030006733 scopus 로고    scopus 로고
    • CD28 costimulation prevents cell death during primary T cell activation
    • Noel, P.J., Boise, L.H., Green, J.M. & Thompson, C.B. (1996), CD28 costimulation prevents cell death during primary T cell activation. J. Immunol., 157, 636-642.
    • (1996) J. Immunol. , vol.157 , pp. 636-642
    • Noel, P.J.1    Boise, L.H.2    Green, J.M.3    Thompson, C.B.4
  • 52
    • 0028222756 scopus 로고
    • Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse
    • Pennline, K.J., Roque-Gaffney, E. & Monahan, M. (1994), Recombinant human IL-10 prevents the onset of diabetes in the nonobese diabetic mouse. Clin. Immunol. Immunopathol., 11, 169-175.
    • (1994) Clin. Immunol. Immunopathol. , vol.11 , pp. 169-175
    • Pennline, K.J.1    Roque-Gaffney, E.2    Monahan, M.3
  • 53
    • 0028603421 scopus 로고
    • Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice
    • Petersen, J.S., Karlsen, A.E., Markholst, H., Worsaae, A., Dyrberg, T. & Michelsen, B. (1994), Neonatal tolerization with glutamic acid decarboxylase but not with bovine serum albumin delays the onset of diabetes in NOD mice. Diabetes, 43, 1478-1484.
    • (1994) Diabetes , vol.43 , pp. 1478-1484
    • Petersen, J.S.1    Karlsen, A.E.2    Markholst, H.3    Worsaae, A.4    Dyrberg, T.5    Michelsen, B.6
  • 54
    • 0028971717 scopus 로고
    • Demonstration of a Th1 cytokine profile in the late phase of NOD insulitis
    • Pilstrom, B., Bjork, L. & Bohme, J. (1995), Demonstration of a Th1 cytokine profile in the late phase of NOD insulitis. Cytokine, 7, 806-814.
    • (1995) Cytokine , vol.7 , pp. 806-814
    • Pilstrom, B.1    Bjork, L.2    Bohme, J.3
  • 55
    • 0029146498 scopus 로고
    • Prevention of autoimmune diabetes in nonobese diabetic female mice by treatment with recombinant glutamic acid decarboxylase (GAD 65)
    • Pleau, J.M., Fernandez-Saravia, F., Esling, A., Homo-Delarche, F. & Dardenne, M. (1995), Prevention of autoimmune diabetes in nonobese diabetic female mice by treatment with recombinant glutamic acid decarboxylase (GAD 65). Clin. Immunol. Immunopathol., 76, 90-95.
    • (1995) Clin. Immunol. Immunopathol. , vol.76 , pp. 90-95
    • Pleau, J.M.1    Fernandez-Saravia, F.2    Esling, A.3    Homo-Delarche, F.4    Dardenne, M.5
  • 56
    • 0027314785 scopus 로고
    • Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice
    • Qin, H.Y., Sadelain, M.W.J., Hitchon, C., Lauzon, J. & Singh, B. (1993), Complete Freund's adjuvant-induced T cells prevent the development and adoptive transfer of diabetes in nonobese diabetic mice. J. Immunol., 150, 2072-2080.
    • (1993) J. Immunol. , vol.150 , pp. 2072-2080
    • Qin, H.Y.1    Sadelain, M.W.J.2    Hitchon, C.3    Lauzon, J.4    Singh, B.5
  • 57
    • 0028989087 scopus 로고
    • IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlate with autoimmune diabetes in nonobese diabetic mice
    • Rabinovitch, A., Suarez-Pinzon, W.L., Sorensen, O., Bleackley, R.C. & Power, R.F. (1995), IFN-γ gene expression in pancreatic islet-infiltrating mononuclear cells correlate with autoimmune diabetes in nonobese diabetic mice. J. Immunol., 154, 4874-4882.
    • (1995) J. Immunol. , vol.154 , pp. 4874-4882
    • Rabinovitch, A.1    Suarez-Pinzon, W.L.2    Sorensen, O.3    Bleackley, R.C.4    Power, R.F.5
  • 60
    • 0029955719 scopus 로고    scopus 로고
    • T cell-mediated maintenance of natural self-tolerance: Its breakdown as a possible cause of various autoimmune diseases
    • Sakaguchi, S., Toda, M., Asano, M., Itoh, M., Morse, S.S. & Sakaguchi, N. (1996), T cell-mediated maintenance of natural self-tolerance: its breakdown as a possible cause of various autoimmune diseases. J. Autoimmun., 9, 211-220.
    • (1996) J. Autoimmun. , vol.9 , pp. 211-220
    • Sakaguchi, S.1    Toda, M.2    Asano, M.3    Itoh, M.4    Morse, S.S.5    Sakaguchi, N.6
  • 63
    • 0023879559 scopus 로고
    • Defective activation of T suppressor cell function in nonobese diabetic mice
    • Serreze, D.V. & Leiter, E.H. (1988), Defective activation of T suppressor cell function in nonobese diabetic mice. J. Immunol., 140, 3801-3807.
    • (1988) J. Immunol. , vol.140 , pp. 3801-3807
    • Serreze, D.V.1    Leiter, E.H.2
  • 64
    • 0027217801 scopus 로고
    • Autoimmune diabetes results from genetic defects manifested by antigen presenting cells
    • Serreze, D.V. (1993), Autoimmune diabetes results from genetic defects manifested by antigen presenting cells. FASEB J., 7, 1092-1096.
    • (1993) FASEB J. , vol.7 , pp. 1092-1096
    • Serreze, D.V.1
  • 65
    • 0027173029 scopus 로고
    • Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice
    • Serreze, D.V., Gaskins, H.R. & Leiter, E.H. (1993), Defects in the differentiation and function of antigen presenting cells in NOD/Lt mice. J. Immunol., 150, 2534-2543.
    • (1993) J. Immunol. , vol.150 , pp. 2534-2543
    • Serreze, D.V.1    Gaskins, H.R.2    Leiter, E.H.3
  • 66
    • 0023879559 scopus 로고
    • Defective activation of T suppressor cell function in nonobese diabetic mice
    • Serreze, D.V. & Leiter, E.H. (1988), Defective activation of T suppressor cell function in nonobese diabetic mice. J. Immunol., 140, 3801-3807.
    • (1988) J. Immunol. , vol.140 , pp. 3801-3807
    • Serreze, D.V.1    Leiter, E.H.2
  • 67
    • 0028603590 scopus 로고
    • Genetic and pathogenic basis of autoimmune diabetes in NOD mice
    • Serreze, D.V. & Leiter, E.H. (1994), Genetic and pathogenic basis of autoimmune diabetes in NOD mice. Curr. Opin. Immunol., 6, 900-906.
    • (1994) Curr. Opin. Immunol. , vol.6 , pp. 900-906
    • Serreze, D.V.1    Leiter, E.H.2
  • 68
    • 0030068383 scopus 로고    scopus 로고
    • + cells correlates with cytokine profiles in the spontaneously autoimmune diabetic mouse
    • + cells correlates with cytokine profiles in the spontaneously autoimmune diabetic mouse. Diabetes, 45, 71-78.
    • (1996) Diabetes , vol.45 , pp. 71-78
    • Shimada, A.1    Rohane, P.2    Fathman, C.G.3    Charlton, B.4
  • 69
    • 0030293443 scopus 로고    scopus 로고
    • CD28/B7 interactions deliver a unique signal to naive t cells that regulates cell survival but not early proliferation
    • Sperling, A., Auger, J.A., Ehst, B.D., Rulifson, I.C., Thompson, C.B. & Bluestone, J.A. (1996), CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation. J. Immunol., 157, 3909-3917.
    • (1996) J. Immunol. , vol.157 , pp. 3909-3917
    • Sperling, A.1    Auger, J.A.2    Ehst, B.D.3    Rulifson, I.C.4    Thompson, C.B.5    Bluestone, J.A.6
  • 70
    • 0028007467 scopus 로고
    • Cholera toxin B subunit: An efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance
    • Sun, J.B., Holmgren, J. & Czerkinsky, C. (1994), Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance. Proc. Natl. Acad. Sci. USA, 891, 10795-10799.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.891 , pp. 10795-10799
    • Sun, J.B.1    Holmgren, J.2    Czerkinsky, C.3
  • 72
    • 0025803954 scopus 로고
    • Insulin prevents adoptive cell transfer of diabetes in the autoimmune nonobese diabetic mouse
    • Thivolet, C.H., Goulot, E., Bedossa, P., Durand, A., Bonnard, M. & Orgiazzi, J. (1991), Insulin prevents adoptive cell transfer of diabetes in the autoimmune nonobese diabetic mouse. Diabetologia, 34, 314-319.
    • (1991) Diabetologia , vol.34 , pp. 314-319
    • Thivolet, C.H.1    Goulot, E.2    Bedossa, P.3    Durand, A.4    Bonnard, M.5    Orgiazzi, J.6
  • 73
    • 0029073090 scopus 로고
    • Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation?
    • Thompson, C.B. (1995), Distinct roles for the costimulatory ligands B7-1 and B7-2 in T helper cell differentiation? Cell, 81, 979-982.
    • (1995) Cell , vol.81 , pp. 979-982
    • Thompson, C.B.1
  • 75
    • 0027908753 scopus 로고
    • Immune response to glutamic acid decarboxylase correlates with insulitis in nonobese diabetic mice
    • Tisch, R., Yang, X.D., Singer, S.M., Liblau, R.S., Fugger, L. & McDevitt, H.O. (1993), Immune response to glutamic acid decarboxylase correlates with insulitis in nonobese diabetic mice. Nature (Lond.), 366, 72-75.
    • (1993) Nature (Lond.) , vol.366 , pp. 72-75
    • Tisch, R.1    Yang, X.D.2    Singer, S.M.3    Liblau, R.S.4    Fugger, L.5    McDevitt, H.O.6
  • 78
    • 0031051747 scopus 로고    scopus 로고
    • Interferon-γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus
    • Von Herrath, M.G. & Oldstone, M.B.A. (1997), Interferon-γ is essential for destruction of β cells and development of insulin-dependent diabetes mellitus. J. Exp. Med., 185, 531-540.
    • (1997) J. Exp. Med. , vol.185 , pp. 531-540
    • Von Herrath, M.G.1    Oldstone, M.B.A.2
  • 80
    • 0022492875 scopus 로고
    • Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice
    • Wicker, L.S., Miller, B.J. & Mullen, Y. (1986), Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice. Diabetes, 35, 855-860.
    • (1986) Diabetes , vol.35 , pp. 855-860
    • Wicker, L.S.1    Miller, B.J.2    Mullen, Y.3
  • 81
    • 0028346888 scopus 로고
    • Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in non obese diabetic mice
    • Wogensen, L., Lee, M.S. & Sarvetnick, N. (1994), Production of interleukin 10 by islet cells accelerates immune-mediated destruction of β cells in non obese diabetic mice. J. Exp. Med., 179, 1379-1384.
    • (1994) J. Exp. Med. , vol.179 , pp. 1379-1384
    • Wogensen, L.1    Lee, M.S.2    Sarvetnick, N.3
  • 82
    • 0028035382 scopus 로고
    • Quantitation of glutamic acid decarboxylase autoantibody levels in prospectively evaluated relatives of patients with type diabetes
    • Yu, L., Gianani, B. & Eisenbarth, G.S. (1994), Quantitation of glutamic acid decarboxylase autoantibody levels in prospectively evaluated relatives of patients with type diabetes. Diabetes, 43, 1229-1233.
    • (1994) Diabetes , vol.43 , pp. 1229-1233
    • Yu, L.1    Gianani, B.2    Eisenbarth, G.S.3
  • 83
    • 0025837184 scopus 로고
    • Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin
    • Zhang, Z.J., Davidson, L., Eisenbarth, G. & Weiner, H.L. (1991), Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin. Proc. Natl. Acad. Sci. USA, 88, 10252-10256.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 10252-10256
    • Zhang, Z.J.1    Davidson, L.2    Eisenbarth, G.3    Weiner, H.L.4
  • 84
    • 0028314298 scopus 로고
    • Lymphocyte subsets in thymus and peripheral lymphoid tissues of aging and diabetic NOD mice
    • Zhang, Z.L., Constantinou, D., Mandel, T.E. & Georgiou, H.M. (1994), Lymphocyte subsets in thymus and peripheral lymphoid tissues of aging and diabetic NOD mice. Autoimmunity, 17, 41-48.
    • (1994) Autoimmunity , vol.17 , pp. 41-48
    • Zhang, Z.L.1    Constantinou, D.2    Mandel, T.E.3    Georgiou, H.M.4
  • 85
    • 0025875068 scopus 로고
    • Altered thymic and peripheral T-lymphocyte repertoire preceding onset of diabetes in NOD mice
    • Zipris, D., Crow, A.R. & Delovitch, T.L. (1991a), Altered thymic and peripheral T-lymphocyte repertoire preceding onset of diabetes in NOD mice. Diabetes, 40, 429-435.
    • (1991) Diabetes , vol.40 , pp. 429-435
    • Zipris, D.1    Crow, A.R.2    Delovitch, T.L.3
  • 86
    • 0025735437 scopus 로고
    • Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice
    • Zipris, D., Lazarus, A.H., Crow, A.R., Hadzija, M. & Delovitch, T.L. (1991b), Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. J. Immunol., 146, 3763-3771.
    • (1991) J. Immunol. , vol.146 , pp. 3763-3771
    • Zipris, D.1    Lazarus, A.H.2    Crow, A.R.3    Hadzija, M.4    Delovitch, T.L.5


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