Natural killer T cells: A potent cytokine-producing cell population

European Cytokine Network

Volumn 8, Issue 3, 1997, Pages 229-237

  Leite De Moraes, Maria C ^a,b   Dy, Michel ^a  

^a CNRS   (France)

^b HÔPITAL NECKER ENFANTS MALADES   (France)

Author keywords

Fas; IFN ; IL 4; Immunoregulation; NK T cells

Indexed keywords

CYTOKINE; FAS ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 4; RECEPTOR SUBTYPE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; CELL KILLING; CELL STIMULATION; HELPER CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PHYSIOLOGY; REVIEW; T LYMPHOCYTE; TARGET CELL;

ANIMALS; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CYTOKINES; HUMANS; INTERFERON TYPE II; INTERLEUKIN-4; KILLER CELLS, NATURAL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; T-LYMPHOCYTE SUBSETS; TH1 CELLS; TH2 CELLS;

ANIMALIA;

EID: 0030773757     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (108)

1. Fowlkes B J, Kruisbeek A M, Ton-That H, Weston M A, Coligan J E, Schwartz R H, Pardoll D M. 1987. A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family. Nature 329: 251.
2. Budd R C, Miescher G C, Howe R C, Lees R K, Bron C, Mac Donald H R. 1987. Developmentally regulated expression of T cell receptor β chain variable domains in immature thymocytes. J. Exp. Med. 166: 577.
3. + subset. J. Immunol. 145: 1039.
4. + thymocytes. J. Immunol. 146: 1113.
5. - thymocytes by class I molecules expressed by hematopoietic cells. J. Exp. Med. 178: 901.
6. + thymocytes selected by MHC class I molecules. Science 263: 1774.
7. - T cells in mice and humans. J. Exp. Med. 180: 1097.
8. + Tcell populations. Int. Immunol. 7: 1157.
9. + T lymphocytes. Science 268: 863.
10. +CD8 thymocytes with specific lymphokine secretion. Eur. J. Immunol. 23: 307.
11. Yoshimoto T, Paul W E. 1994. CD4pos, NK1.1pos Tcells promptly produce interleukin-4 in response to in vivo challenge with anti-CD3. J. Exp. Med. 179: 1285.
12. + T cells are a potential source of IL-4 during primary immune response. J. Immunol. 155: 4544.
13. + thymocytes. J. Exp. Med. 180: 395.
14. - single-positive thymocyte subpopulation that expresses a highly skewed T cell antigen receptor Vβ family. Proc. Natl. Acad. Sci. USA 89: 6506.
15. +-like thymocytes in the NOD mouse. Eur. J. Immunol. 26: 2989.
16. - cells. J. Exp. Med. 179: 1957.
17. -α/β T cells demonstrates preferential use of several Vβ genes and an invariant TCR α chain. J. Exp. Med. 178: 1.
18. - T cells. J. Exp. Med. 180: 1171.
19. + thymocytes. Eur. J. Immunol. 26: 1424.
20. Azuara V, Levraud J P, Lembezat M P, Pereira P. 1997. A novel subset of adult gamma delta thymocytes that secretes a distinct pattern of cytokines and expresses a very restricted T cell receptor repertoire. Eur. J. Immunol. 27: 544.
21. -CD8 thymocytes. Int. Immunol. 7: 213.
22. Herron L R, Eisenberg R A, Roper E, Kakkanaiah V N, Cohen P L, Kotzin B L. 1993. Selection of the T cell receptor repertoire in lpr mice. J. Immunol. 151: 3450.
23. Cohen P L, Eisenberg R A. 1991. lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. (Review) Annu. Rev. Immunol. 57: 243.
24. Watanabe-Fukunaga R, Brannan C I, Copeland N G, Jenkins N A, Nagata S. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356: 314.
25. Takahashi T, Tanaka M, Brannan C I, Jenkins N A, Copeland N G, Suda T, Nagata S. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76: 969.
26. + cells. J. Immunol. 145: 3209.
27. + T cells are present within a population of intermediate TCR cells. J. Immunol. 155: 2972.
28. Guy-Grand D, Cuénod-Jabri B, Malassis-Seris M, Selz F, Vassalli P. 1996. Complexy of the mouse gut T cell immune system: identification of two distinct natural killer T cell intraepithelial lineages. Eur. J. Immunol. 26: 2248.
29. +CD8 murine thymocytes positively selected by class I molecules. J. Exp. Med. 180: 653.
30. + T cells in major histocompatibility complex class II-deficient mice. J. Exp. Med. 182: 993.
31. Brutkiewicz R R, Bennink J R, Yewdell J W, Bendelac A. 1995. TAP-independent, β2-microglobulin-dependent surface expression of functional mouse CD1.1 J. Exp. Med. 182: 1913.
32. Yewdell J W, Bennink J R. 1992. Cell biology of antigen processing and presentation to major histocompatibility complex class I molecule-restricted T lymphocytes. (Review) Adv. Immunol. 52: 1.
33. Porcelli S A. 1995. The CD1 family: a third lineage of antigen presentation molecules. (Review) Adv. Immunol. 59: 1.
34. + T cells by CD1-expressing cortical thymocytes. J. Exp. Med. 182: 2091.
35. Sieling P A, Chatterjee D, Porcelli S A, Prigozy T I, Mazzaccaro R J, Soriano T, Bloom B R, Brenner M B, Kronenberg M, Brennan P J, Modlin R L. 1995. CD1-restricted T cell recognition of microbial lypoglycan antigens. Science 269: 227.
36. Castaño A R, Tangri S, Miller J E, Holcombe H R, Jackson M R, Huse W D, Kronenberg M, Peterson P A. 1995. Peptide binding and presentation by mouse CD1. Science 269: 223.
37. Smiley S T, Kaplan M H, Grusby M J. 1997. Immunoglobulin E production in the absence of interleukin-4-secreting CD1-dependent cells. Science 275: 977.
38. + cells responsible for acute marrow graft rejection are present in thymus-deficient mice. J. Immunol. 149: 403.
39. Ohteki T, Okuyama R, Seki S, Abo T, Sugiura K, Kusumi A, Ohmori T, Watanabe H, Kumagai K. 1992. Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice. J. Immunol. 149: 1562.
40. Makino Y, Yamagata N, Sasho T, Adachi Y, Kanno R, Koseki H, Kanno M, Taniguchi M. 1993. Extrathymic development of Vα14-positive T cells. J. Exp. Med. 177: 1399.
41. + T lymphocytes: thymic selection by self antigen. J. Immunol. 157: 4379.
42. + cells in the liver of mice. J. Exp. Med. 180: 699.
43. + thymocytes. J. Immunol. 151: 546.
44. + thymocyte population associated with intact Fas antigen expression on the target. J. Exp. Med. 180: 423.
45. + αβ T cells activated by IL-12 as a major effector in inhibition of experimental tumor metastasis. J. Immunol. 156: 3366.
46. + thymocytes. Int. Immunol. 9: 73.
47. Yokoyama W M, Seaman W E. 1993. The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killers cells: the NK gene complex. (Review) Annu. Rev. Immunol. 11: 613.
48. Brown M G, Scalzo A A, Matsumoto K, Yokoyama W M. 1997. The natural killer gene complex: a genetic basis for understanding natural killer cell function and innate immunity. Immunol. Rev. 155: 53.
49. Bezouska K, Yuen C T, O'Brien J, Childs R A, Chai W, Lawson A M, Drbal K, Fiserova A, Pospisil M, Feizi T. 1994. Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity. Nature 372: 150.
50. Bezouska K, Yuen C T, O'Brien J, Childs R A, Chai W, Lawson A M, Drbal K, Fiserova A, Pospisil M, Feizi T. 1996. Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity. Corrections. Nature 380: 559.
51. Long E O, Burshtyn D N, Clark W P, Peruzzi M, RajagopalanS, Rojo S, Wagtmann N, Winter C C. 1997. Killer cell inhibitory receptors: diversity, specificity, and function. Immunol. Rev. 155: 135.
52. Scharton-Kersten T M, Sher A. 1997. Role of natural killer cells in innate resistance to protozoan infections. (Review) Curr. Opin. Immunol. 9: 44.
53. + αβ T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells. J. Immunol. 156: 2436.
54. Herbelin A, Machavoine F, Schneider E, Papiernik M, Dy M. 1992. IL-7 is requisite for IL-1-induced thymocyte proliferation. Involvement of IL-7 in the synergic effects of granulocyte-macrophage colony stimulating factor of tumor necrosis factor with IL-1. J. Immunol. 148: 99.
55. Herbelin A, Machavoine F, Vicari A, Schneider E, Papiernik M, Ziltener H, Pénit C, and Dy M. 1994. Endogenous granulocyte-macrophage colony-stimulating factor is involved in IL-1- and IL-7-induced murine thymocyte proliferation. J. Immunol. 153: 1973.
56. Nagata S, Golstein P. 1995. The Fas death factor. (Review) Science 267: 1449.
57. Nagata S. 1997. Apoptosis by death factor. (Review) Cell 88: 355.
58. Suda T, Okazaki T, Naito Y, Yokota T, Arai N, Ozaki S, Nakao K, Nagata S. 1995. Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154: 3806.
59. Castro J E, Listman J A, Jacobson B A, Wang Y, Lopez P A, Ju S, Finn P W, Perkins D L. 1996. Fas modulation of apoptosis during negative selection of thymocytes. Immunity 5: 617.
60. Singer G G, Abbas A K. 1994. The Fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice. Immunity 1: 365.
61. + NK T cells associated with disease development in autoimmune-prone mice. J. Immunol. 156: 4035.
62. Sumida T, Sakamoto A, Murata H, Makino Y, Takahashi H, Yoshida S, Nishioka K, Iwamoto I, Taniguchi M. 1995. Selective reduction of T cells bearing invariant Vα24JαQ antigen receptor in patients with systemic sclerosis. J. Exp. Med. 182: 1163.
63. Ogasawara J, Watanabe-Fukunaga R, Adachi M, Matsuzawa A, Kasugai T, Kitamura Y, Itoh N, Suda T, Nagata S. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364: 806.
64. - T cells associated with abnormal Fas expression and hypereosinophilia. J. Exp. Med. 183: 1071.
65. Takenada K, Nagafugi K, Harada M, Mizuno S, Miyamoto T, Makino S, Gondo H, Okamura T, Niho Y. 1996. In vitro expansion of hematopoietic progenitor cells induces functional expression of Fas antigen (CD95). Blood 8: 2871.
66. Keiner G S, Kennedy J, Bacon K B, Kleyensteuber S, Largaespada D A, Jenkins N A, Copeland N G, Bazan J F, Moore K W, Schall T J, Zlotnik A. 1994. Lymphotactin: a novel cytokine which represents a new class of chemokine. Science 266: 1395.
67. Kopf M, Le Gros G, Bachmann M, Lamers M C, Bluethmann H, Kohler G. 1993. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 362: 245.
68. Kaplan M H, Schindler U, Smiley S T, Grusby M J. 1996. STAT6 is required for mediating responses to IL-4 and for development of Th2 cells. Immunity 4: 313.
69. + T cells. (Review) Annu. Rev. Immunol. 12: 635.
70. Mosmann T R, Coffman R L. 1989. Th1 and Th2 cells: different patterns of lymphokine secretion lead to different functional properties. (Review) Annu. Rev. Immunol. 7: 145.
71. Abbas A K, Murphy K M, Sher A. 1996. Functional diversity of helper T lymphocytes. (Review) Nature 383: 787.
72. Reiner S L, Locksle R M. 1995. The regulation of immunity to Leishmania major. (Review) Annu. Rev. Immunol. 13: 151.
73. Sher A, Coffman R L. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. (Review) Ann. Rev. Immunol. 10: 385.
74. Locksley R M. 1994. Th2 cells: help for helminths. (Review) J. Exp. Med. 179: 1405.
75. + T cells in the pathogenesis of organ-specific autoimmune diseases. (Review) Immunol. Today 16: 34.
76. Magram J, Connaughton S E, Warrier R R, Carjaval D M, Wu C Y, Ferrante J, Stewart C, Sarmiento U, Faherty D A, Gately M K. 1996. IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses. Immunity 4: 471.
77. Kaplan M H, Sun Y L, Hoey T, Grusby M J. 1996. Impaired IL-12 responses and enhanced development of Th2 cells in STAT4-deficent mice. Nature 382: 174.
78. Bradley L M, Dalton D K, Croft M. 1996. A direct role for IFN-γ in regulation of Th1 cell development. J. Immunol. 157: 1350.
79. Pernis A, Gupta S, Gollob K J, Garfein E, Coffman R L, Schindler C, Rothman P. 1995. Lack of interferon-γ receptor β chain and the prevention of interferon-γ signaling in TH1 cells. Science 269: 245.
80. Trinchieri G. 1995. Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptative immunity. (Review) Annu. Rev. Immunol. 13: 251.
81. Hunter C A, Subauste C S, Van Cleave V H, Remington J S. 1994. Production of gamma interferon by natural killer cells from Toxoplasma gondii-infected SCID mice: regulation by interleukin-10, interleukin-12, and tumor necrosis factor alpha. Infect. Immunol. 62: 2818.
82. Dy M, Jankovic D, Ploemacher R, Theze J, Schneider E. 1991. Concomitant histamine, IL-4 and IL-6 production by hematopoietic progenitor subsets in response to IL-3. Exp. Hematol. 19: 934.
83. + cells. (Review) Adv. Immunol. 53: 1.
84. Sabin E A, Kopf M A, Pearce E J. 1996. Schistosoma mansoni egg-induced early IL-4 production is dependent upon IL-5 and eosinophils. J. Exp. Med. 184: 1871.
85. + T cells that promptly produce interleukin- 4. Proc. Natl. Acad. Sci USA 92: 11931.
86. + T cells in a TH2 response and in immunoglobulin E production. Science 270: 1845.
87. - T cells with a skewed variable region repertoire after infection with Listeria monocytogenes. Eur. J. Immunol. 25: 1985.
88. + TCRα/β intermediate liver lymphocytes are down-regulated by Listeria monocytogenes. Eur. J. Immunol. 25: 3321.
89. + T cells which are NK1.1 . Eur. J. Immunol. 25: 3298.
90. - T cell population. J. Immunol. 157: 4421.
91. + effector function against intracellular infection. J. Exp. Med. 184: 131.
92. Guéry J C, Galbiati F, Smiroldo S, Adorini L. 1996. Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and β2-microglobulin-deficient BALB/c mice. J. Exp. Med. 183: 485.
93. + T cells are not essential for T helper cell 2 immune responses. J. Exp. Med. 184: 1295.
94. Zhang Y, Rogers K H, Lewis D B. 1996. β2-microglobulin-dependent T cells are dispensable for allergen-induced T helper 2 responses. J. Exp. Med. 184: 1507.
95. + T cells from interleukin-7 deficient mice have a normal distribution and selection but exhibit impaired cytokine production. Int. Immunol. 8: 1759.
96. + T cell defective IL-4 production in the non-obese diabetic mouse. Int. Immunol. 8: 1751.
97. Trinchieri G, Gerosa F. 1996. Immunoregulation by IL-12. (Review) J. Leukoc. Biol. 54: 505.
98. Leite-de-Moraes M C, Moreau G, Arnould A, Machavoine F, Garcia C, Papiernik M, Dy M. 1997. The IL-4-producing NK T cells are biased toward IFN-γ production by IL-12. Submitted.
99. + T cells upon NKR-P1 cross-linking. J. Exp. Med 183: 2391.
100. + T cells with potent cytotoxicity in the liver of mice via production of IL-12 from Kupffer cells. J. Immunol. 156: 2436.
101. + T cells during initiation of infection. J. Exp. Med. 179: 447.
102. + T-cells through IL-12 produced by Listeria-induced macrophages. Science 260: 547.
103. Conboy I M, De Kruyff R H, Tate K M, Cao Z A, Moore T A, Umetsu D T, Jones P P. 1997. Novel genetic regulation of T helper 1 (Th1)/Th2 cytokine production and encephalitogenicity in imbred mouse strains. J. Exp. Med. 185: 439.
104. Cause W C, Halvorson M J, Lu P, Greenwald R, Linsley P, Urban J F, Finkelman F D. 1997. The function of costimulatory molecules and the development of IL-4-producing T cells. Immunol. Today 18: 115.
105. Coffman R L, von de Weid T. 1997. Multiple pathways for the initiation of T helper 2 (Th2) responses. J. Exp. Med. 185: 373.
106. Hsieh C S, Macatonia S E, O'Garra A, Murphy K M. 1995. T cell helper background determines default T helper phenotype in vitro. J. Exp. Med. 181: 713.
107. Guler M L, Gorham J D, Hsieh C S, Mackey A J, Steen R G, Dietrich W F, Murphy K M. 1996. Genetic susceptibility to Leishmania: IL-12 responsiveness in Th1 cell development. Science 271: 984.
108. + T cells. J. Exp. Med. 185: 461.