Molecular simulation of dynorphin A-(1-10) binding to extracellular loop 2 of the κ-opiod receptor. A model for receptor activation

Journal of Medicinal Chemistry

Volumn 40, Issue 20, 1997, Pages 3254-3262

  Paterlini, Germana ^a   Portoghese, Philip S ^a   Ferguson, David M ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNORPHIN A DERIVATIVE; DYNORPHIN[1-10]; KAPPA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; MOLECULAR MODEL; PROTEIN SECONDARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; COMPUTER SIMULATION; DYNORPHINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, OPIOID, KAPPA; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030769046     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970252j     Document Type: Article

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