-
1
-
-
0000315780
-
Opioid analgesics and antagonists
-
Gilman, A. G., Rall, T. W., Nies, A. W., and Taylor, P. (eds.), Pergamon Press, New York
-
Jaffe, J. H., and Martin, W. R. 1990. Opioid analgesics and antagonists. Pages 485-521, in Gilman, A. G., Rall, T. W., Nies, A. W., and Taylor, P. (eds.), The Pharmacological Basis of Therapeutics, Pergamon Press, New York.
-
(1990)
The Pharmacological Basis of Therapeutics
, pp. 485-521
-
-
Jaffe, J.H.1
Martin, W.R.2
-
2
-
-
0004215151
-
-
Springer-Verlag, Berlin
-
Herz, A., Akil, H. A., and Simon, E. J. (eds.) 1993. Opioids I. Springer-Verlag, Berlin.
-
(1993)
Opioids I
-
-
Herz, A.1
Akil, H.A.2
Simon, E.J.3
-
4
-
-
0027050144
-
Cloning of a delta opioid receptor by functional expression
-
Evans, C. E., Keith, D. E., Morrison, H., Magendzo, K., and Edwards, R. H. 1992. Cloning of a delta opioid receptor by functional expression. Science 258:1952-1955.
-
(1992)
Science
, vol.258
, pp. 1952-1955
-
-
Evans, C.E.1
Keith, D.E.2
Morrison, H.3
Magendzo, K.4
Edwards, R.H.5
-
5
-
-
0027052952
-
The δ-opioid receptor: Isolation of a cDNA by expression cloning and pharmacological characterization
-
Kieffer, B. L., Befort, K., Gaveriaux-Ruff, C., and Hirth, C. G. 1992. The δ-opioid receptor: isolation of a cDNA by expression cloning and pharmacological characterization. Proc. Natl. Acad. Sci. USA 89:12048-12052.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 12048-12052
-
-
Kieffer, B.L.1
Befort, K.2
Gaveriaux-Ruff, C.3
Hirth, C.G.4
-
6
-
-
0027168912
-
Cloning and functional comparison of κ and δ opioid receptors from mouse brain
-
Yasuda, K., Raynor, K., Kong, H., Breder, C. D., Takeda, J., Reisine, T., and Bell, G. I. 1993. Cloning and functional comparison of κ and δ opioid receptors from mouse brain. Proc. Natl. Acad. Sci. USA 90:6736-6740.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 6736-6740
-
-
Yasuda, K.1
Raynor, K.2
Kong, H.3
Breder, C.D.4
Takeda, J.5
Reisine, T.6
Bell, G.I.7
-
7
-
-
0027441941
-
μ opiate receptor: cDNA cloning and expression
-
Wang, J. B., Imai, Y., Eppler, C. P., Gregor, P., Spivak, C. E., and Uhl, G. R. 1993. μ opiate receptor: cDNA cloning and expression. Proc. Natl. Acad. Sci. USA 90:10230-10234.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10230-10234
-
-
Wang, J.B.1
Imai, Y.2
Eppler, C.P.3
Gregor, P.4
Spivak, C.E.5
Uhl, G.R.6
-
8
-
-
0027202213
-
Molecular cloning and functional expression of a μ opiate receptor from rat brain
-
Chen, Y., Mestek, A., Liu, J., Hurley, J. A., and Yu, L. 1993. Molecular cloning and functional expression of a μ opiate receptor from rat brain. Molecular Pharmacology 44:8-12.
-
(1993)
Molecular Pharmacology
, vol.44
, pp. 8-12
-
-
Chen, Y.1
Mestek, A.2
Liu, J.3
Hurley, J.A.4
Yu, L.5
-
9
-
-
0027275029
-
Primary structures and expression from cDNAs of rat opioid δ and μ subtypes
-
Fukuda, K., Kato, S., Mon, K., Nishi, M., and Takeshima, H. 1993. Primary structures and expression from cDNAs of rat opioid δ and μ subtypes. FEBS Lett. 327:311-314.
-
(1993)
FEBS Lett.
, vol.327
, pp. 311-314
-
-
Fukuda, K.1
Kato, S.2
Mon, K.3
Nishi, M.4
Takeshima, H.5
-
10
-
-
0027381434
-
Cloning and pharmacological characterization of a rat κ opioid receptor
-
Meng, F., Xie, G.-X., Thompson, R. C., Mansour, A., Goldstein, A., Watson, S. J., Akil, H. 1993. Cloning and pharmacological characterization of a rat κ opioid receptor. Proc. Natl. Acad. Sci. USA 90:9954-9958.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 9954-9958
-
-
Meng, F.1
Xie, G.-X.2
Thompson, R.C.3
Mansour, A.4
Goldstein, A.5
Watson, S.J.6
Akil, H.7
-
11
-
-
0027504836
-
Cloning and pharmacological characterization of a rat μ opioid receptor
-
Thompson, R. C., Mansour, A., Akil, H., and Watson, S. J. 1993 Cloning and pharmacological characterization of a rat μ opioid receptor. Neuron 11:903-913.
-
(1993)
Neuron
, vol.11
, pp. 903-913
-
-
Thompson, R.C.1
Mansour, A.2
Akil, H.3
Watson, S.J.4
-
12
-
-
0026681102
-
Three-dimensional Structure for the β2 Adrenergic Receptor Protein Based on Computer Modeling Studies
-
Maloneyhuss, K., and Lybrand, T. P. 1992. Three-dimensional Structure for the β2 Adrenergic Receptor Protein Based on Computer Modeling Studies. J. Mol. Biol. 225:859-871.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 859-871
-
-
Maloneyhuss, K.1
Lybrand, T.P.2
-
13
-
-
0025881062
-
Three-Dimensional Models of Neurotransmitter Binding G-Protein-Coupled Receptors
-
Hibert, M. F., Trumpp-Kallmeyer, S., Bruinvels, A., and Bruinvels, A. 1991. Three-Dimensional Models of Neurotransmitter Binding G-Protein-Coupled Receptors. Molecular Pharmacology. 40:8-15.
-
(1991)
Molecular Pharmacology
, vol.40
, pp. 8-15
-
-
Hibert, M.F.1
Trumpp-Kallmeyer, S.2
Bruinvels, A.3
Bruinvels, A.4
-
14
-
-
0026660322
-
Modeling of G-Protein-Coupled Receptors: Application to Dopamine, Adrenaline, Serotonin Acetylcholine, and Mammalian Opsin Receptors
-
Trumpp-Kallmeyer, S., Hoflack, J., Bruinvels, A., and Hibert, M. 1992. Modeling of G-Protein-Coupled Receptors: Application to Dopamine, Adrenaline, Serotonin Acetylcholine, and Mammalian Opsin Receptors. J. Med. Chem. 35:3448-3462.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 3448-3462
-
-
Trumpp-Kallmeyer, S.1
Hoflack, J.2
Bruinvels, A.3
Hibert, M.4
-
16
-
-
11944268922
-
Molecular Mechanism of Action in Non-peptide Ligands for Peptide Receptors
-
Schwartz, T. W., Gether, U., Schambye, H. T., and Hjorth, S. A. 1995 Molecular Mechanism of Action in Non-peptide Ligands for Peptide Receptors. Current Pharmaceutical Design 1:355-372.
-
(1995)
Current Pharmaceutical Design
, vol.1
, pp. 355-372
-
-
Schwartz, T.W.1
Gether, U.2
Schambye, H.T.3
Hjorth, S.A.4
-
17
-
-
0027933763
-
Locating ligand-binding sites in 7TM receptors by protein engineering
-
Schwartz, T. W. Locating ligand-binding sites in 7TM receptors by protein engineering. 1994. Curr. Opin. Biotech. 5:434-444.
-
(1994)
Curr. Opin. Biotech.
, vol.5
, pp. 434-444
-
-
Schwartz, T.W.1
-
18
-
-
85035184602
-
Structural Model of the κ-Opioid Receptor Transmembrane Domain and Proposed Docking Mode for Non-selective and Selective Antagonists
-
manuscript in preparation
-
Metzger, T. G., Paterlini, M. G., Portoghese, P. S., and Ferguson, D. M. 1996. Structural Model of the κ-Opioid Receptor Transmembrane Domain and Proposed Docking Mode for Non-selective and Selective Antagonists. J. Med. Chem. manuscript in preparation.
-
(1996)
J. Med. Chem.
-
-
Metzger, T.G.1
Paterlini, M.G.2
Portoghese, P.S.3
Ferguson, D.M.4
-
19
-
-
0028071564
-
The SWISS-PROT protein sequence data bank: Current Status
-
Bairoch, A. and Boeckmann, B. The SWISS-PROT protein sequence data bank: Current Status. Nucleic Acids Res., 1994, 22, 3578-3580.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 3578-3580
-
-
Bairoch, A.1
Boeckmann, B.2
-
20
-
-
0027160197
-
Backbone-dependent rotamer library for proteins: Application to sidechain prediction
-
Dunbrack, R. L. Jr. and Karplus, M. 1993. Backbone-dependent rotamer library for proteins: Application to sidechain prediction. J. Mol. Biol. 230:543-574.
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 543-574
-
-
Dunbrack Jr., R.L.1
Karplus, M.2
-
21
-
-
0004279414
-
-
University of California, San Francisco
-
Pearlman, D. A., Case, D. A., Caldwell, J. W., Ross, W. S., Cheatham III, T. E., Ferguson, D. M., Seibel, G., Singh, U. C., Weiner, P. K., and Kollman, P. A. 1995. AMBER4.1, University of California, San Francisco.
-
(1995)
AMBER4.1
-
-
Pearlman, D.A.1
Case, D.A.2
Caldwell, J.W.3
Ross, W.S.4
Cheatham III, T.E.5
Ferguson, D.M.6
Seibel, G.7
Singh, U.C.8
Weiner, P.K.9
Kollman, P.A.10
-
22
-
-
0029011701
-
A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules
-
Cornell, W. D., Cieplak, P., Bayly, C. I., Gould, I. R., Merz, K. M., Ferguson, D. M., Spellmeyer, D. C., Fox, T., Caldwell, J. W., and Kollman, P. A. 1995. A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules. J. Am. Chem. Soc. 117:5179-5197.
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.I.3
Gould, I.R.4
Merz, K.M.5
Ferguson, D.M.6
Spellmeyer, D.C.7
Fox, T.8
Caldwell, J.W.9
Kollman, P.A.10
-
23
-
-
84880653336
-
-
Gaussian Inc. Pittsburgh PA
-
Frisch, M. J., Trucks, G. W., Schlegel, H. B., Gill, P. M. W., Johnson, B. G., Wong, M. W., Foresman, J. B., Robb, M. A., Head-Gordon, M., Replogle, E. S., Gomperts, R., Andres, J. L., Raghavachari, K., Binkley, J. S., Gonzalez, C., Wolfram, J., Martin, R. L., Fox, J., Defrees, D. J., Baker, J., Stewart, J. J. P., and Pople, J. A. 1993. Gaussian 92/DFT, Gaussian Inc. Pittsburgh PA.
-
(1993)
Gaussian 92/DFT
-
-
Frisch, M.J.1
Trucks, G.W.2
Schlegel, H.B.3
Gill, P.M.W.4
Johnson, B.G.5
Wong, M.W.6
Foresman, J.B.7
Robb, M.A.8
Head-Gordon, M.9
Replogle, E.S.10
Gomperts, R.11
Andres, J.L.12
Raghavachari, K.13
Binkley, J.S.14
Gonzalez, C.15
Wolfram, J.16
Martin, R.L.17
Fox, J.18
Defrees, D.J.19
Baker, J.20
Stewart, J.J.P.21
Pople, J.A.22
more..
-
24
-
-
85035186617
-
-
note
-
Molecular graphics images were produced using the MidasPlus program from the Computer Graphics Laboratory, University of California, San Francisco (supported by NIH RR-01081).
-
-
-
-
25
-
-
0029013360
-
Analysis of Selective Binding Epitopes for the κ-Opioid Receptor Antagonist Nor-binaltorphimine
-
Hjorth, S. A., Thirstrup, K., Grandy, D. K.., and Schwartz, T. W. 1995. Analysis of Selective Binding Epitopes for the κ-Opioid Receptor Antagonist Nor-binaltorphimine. Molecular Pharmacology 47:1089-1094.
-
(1995)
Molecular Pharmacology
, vol.47
, pp. 1089-1094
-
-
Hjorth, S.A.1
Thirstrup, K.2
Grandy, D.K.3
Schwartz, T.W.4
-
26
-
-
0029017044
-
Chimeric Study of the Molecular Basis of Affinity and Selectivity of the κ and the δ Opioid Receptors
-
Meng, F., Hoversten, M. T., Thompson, R. C., Taylor, L., Watson, S. J., and Akil, H. A. 1995. Chimeric Study of the Molecular Basis of Affinity and Selectivity of the κ and the δ Opioid Receptors. J. Biol. Chem. 270:12730-12736.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 12730-12736
-
-
Meng, F.1
Hoversten, M.T.2
Thompson, R.C.3
Taylor, L.4
Watson, S.J.5
Akil, H.A.6
-
27
-
-
0029586680
-
Studies on μ and δ-opioid receptor selectivity utilizing chimeric and site-mutagenized receptors
-
Wang, W. W., Shahrestanifar, M., Jin, J., and Howells, R. D. 1995. Studies on μ and δ-opioid receptor selectivity utilizing chimeric and site-mutagenized receptors. Proc. Natl. Acad. Sci. USA 92:12436-12440.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 12436-12440
-
-
Wang, W.W.1
Shahrestanifar, M.2
Jin, J.3
Howells, R.D.4
-
28
-
-
0028170438
-
μ-Opioid Receptor: Charged Transmembrane Domain Amino Acids Are Critical for Agonist Recognition and Intrinsic Activity
-
Surratt, C. K., Johnson, P. S., Moriwaki, A., Seidleck, B. K., Blaschak, C. J., Wang, J. B., and Uhl, G. R. 1994. μ-Opioid Receptor: Charged Transmembrane Domain Amino Acids Are Critical for Agonist Recognition and Intrinsic Activity. J. Biol. Chem. 269: 20548-20553.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 20548-20553
-
-
Surratt, C.K.1
Johnson, P.S.2
Moriwaki, A.3
Seidleck, B.K.4
Blaschak, C.J.5
Wang, J.B.6
Uhl, G.R.7
-
29
-
-
0029937609
-
Role of Aromatic Transmembrane Residues of the δ-Opioid Receptor in Ligand Recognition
-
Befort, K., Tabbara, L., Kling, D., Maigret, B., Kieffer, B. L. 1996. Role of Aromatic Transmembrane Residues of the δ-Opioid Receptor in Ligand Recognition. J. Biol. Chem. 271:10161-10168.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 10161-10168
-
-
Befort, K.1
Tabbara, L.2
Kling, D.3
Maigret, B.4
Kieffer, B.L.5
-
30
-
-
0030194704
-
-
in press
-
Metzger, T. M., Paterlini, M. G., Portoghese, P. S., Ferguson, D. M. 1996. J. Chem. Inf. Comp. Sci., 36:0000 (in press).
-
(1996)
J. Chem. Inf. Comp. Sci.
, vol.36
-
-
Metzger, T.M.1
Paterlini, M.G.2
Portoghese, P.S.3
Ferguson, D.M.4
-
31
-
-
0026057332
-
Allele Specific Activation of Genetically Engineered Receptors
-
Strader, C. D., Gaffrey, T., Sugg, E. E., Candelore, M. R., Key, R., Patchett, A. A., and Dixon, R. A. F. 1991. Allele Specific Activation of Genetically Engineered Receptors. J. Biol. Chem. 266:5-8.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 5-8
-
-
Strader, C.D.1
Gaffrey, T.2
Sugg, E.E.3
Candelore, M.R.4
Key, R.5
Patchett, A.A.6
Dixon, R.A.F.7
-
32
-
-
0024344941
-
Identification of Two Serine Residues Involved in Agonist Activation of Allele Specific Activation of β-adrenergic Receptor
-
Strader, C. D., Candelore, M. R., Hill, W. S., Sigal, I. S., Dixon, R. A. F. 1989. Identification of Two Serine Residues Involved in Agonist Activation of Allele Specific Activation of β-adrenergic Receptor. J. Biol. Chem. 264:13572-13578.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 13572-13578
-
-
Strader, C.D.1
Candelore, M.R.2
Hill, W.S.3
Sigal, I.S.4
Dixon, R.A.F.5
-
33
-
-
0024519931
-
Structural Basis of β-adrenergic Receptor Function
-
Strader, C. D., Sigal, I. S., and Dixon, R. A. F. Structural Basis of β-adrenergic Receptor Function. FASEB J. 1989, 3, 1825-1832.
-
(1989)
FASEB J.
, vol.3
, pp. 1825-1832
-
-
Strader, C.D.1
Sigal, I.S.2
Dixon, R.A.F.3
-
34
-
-
0030040907
-
The Conserved Aspartate Residue in the Third Putative Transmembrane Domain of the δ-Opioid Receptor Is not the Anionic Counterpart for Cationic Opiate Binding but Is a Constituent of the Receptor Binding Site
-
Befort, K., Tabbara, L., Bausch, S., Chavkin, C., Evans, C. E., and Kieffer, B. L. 1996. The Conserved Aspartate Residue in the Third Putative Transmembrane Domain of the δ-Opioid Receptor Is not the Anionic Counterpart for Cationic Opiate Binding but Is a Constituent of the Receptor Binding Site. Molecular Pharmacology. 49:216-223.
-
(1996)
Molecular Pharmacology
, vol.49
, pp. 216-223
-
-
Befort, K.1
Tabbara, L.2
Bausch, S.3
Chavkin, C.4
Evans, C.E.5
Kieffer, B.L.6
-
35
-
-
0028099965
-
Amino Acids in the Cloned Mouse κ Receptor that Are Necessary for the High Afinity Agonist Binding but Not Antagonist Binding
-
Kong, U., Raynor, K., and Reisine, T. 1994. Amino Acids in the Cloned Mouse κ Receptor that Are Necessary for the High Afinity Agonist Binding but Not Antagonist Binding. Regulatory Peptides 54:155-156.
-
(1994)
Regulatory Peptides
, vol.54
, pp. 155-156
-
-
Kong, U.1
Raynor, K.2
Reisine, T.3
-
36
-
-
0028104682
-
Differential Binding Domains of Peptide and Non-peptide Ligands in the Cloned Rat κ-Opioid Receptor
-
Xue, J.-C., Chen, C., Zhu, J., Kunapuli, S. P., de Riel, J. K., Yu, L., and Liu-Chen, L.-Y. 1994. Differential Binding Domains of Peptide and Non-peptide Ligands in the Cloned Rat κ-Opioid Receptor. J. Biol. Chem. 269:30195-30199.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30195-30199
-
-
Xue, J.-C.1
Chen, C.2
Zhu, J.3
Kunapuli, S.P.4
De Riel, J.K.5
Yu, L.6
Liu-Chen, L.-Y.7
-
37
-
-
0027329030
-
Synthesis and κ Opioid Antagonist Selectivity of a Norbinaltorphimine Congener. Identification of the Address Moiety Required for κ Antagonist Activity
-
Lin, C.-E., Takemori, A. E., and Portoghese, P. S. 1993. Synthesis and κ Opioid Antagonist Selectivity of a Norbinaltorphimine Congener. Identification of the Address Moiety Required for κ Antagonist Activity. J. Med. Chem. 36:2412-2415.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 2412-2415
-
-
Lin, C.-E.1
Takemori, A.E.2
Portoghese, P.S.3
-
38
-
-
0027402575
-
A Remarkable Change of Opioid Receptor Selectivity on the Attachment of a Peptidomimetic κ Address Element to the δ Antagonist, Naltrindole: 5′-[(N2-Alkylamidino) methyl]naltrindole Derivatives as a Novel Class of κ Opioid Receptor Antagonists
-
Olmstead, S. L., Takemori, A. E., and Portoghese, P. S. 1993. A Remarkable Change of Opioid Receptor Selectivity on the Attachment of a Peptidomimetic κ Address Element to the δ Antagonist, Naltrindole: 5′-[(N2-Alkylamidino) methyl]naltrindole Derivatives as a Novel Class of κ Opioid Receptor Antagonists. J. Med. Chem. 36:179-180.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 179-180
-
-
Olmstead, S.L.1
Takemori, A.E.2
Portoghese, P.S.3
-
39
-
-
0030568457
-
δ-Opioid Receptor: The third extracellular loop determines naltrindole selectivity
-
Li, X., Varga, E. V., Stropva, D., Zalewska, T., Malatynska, E., Knapp, R. J., Roeske, W. R., and Yamamura, U. I. 1996. δ-Opioid Receptor: the third extracellular loop determines naltrindole selectivity. Eur. J. Pharmacol. 300:R1-R2.
-
(1996)
Eur. J. Pharmacol.
, vol.300
-
-
Li, X.1
Varga, E.V.2
Stropva, D.3
Zalewska, T.4
Malatynska, E.5
Knapp, R.J.6
Roeske, W.R.7
Yamamura, U.I.8
-
40
-
-
0028143479
-
Human κ Opiate Receptor Second Extracellular Loop Elevates Dynorphin's Affinity for Human μ/κ Chimeras
-
Wang, J. B., Johnson, P. S., Wu, J. M., Wang, W. F., and Uhl, G. R. 1994. Human κ Opiate Receptor Second Extracellular Loop Elevates Dynorphin's Affinity for Human μ/κ Chimeras. J. Biol. Chem. 269:25966-25969.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 25966-25969
-
-
Wang, J.B.1
Johnson, P.S.2
Wu, J.M.3
Wang, W.F.4
Uhl, G.R.5
|