Gene expression in the limbless mutant: Polarized gene expression in the absence of Shh and an AER

Developmental Biology

Volumn 179, Issue 2, 1996, Pages 339-346

  Noramly, Selina ^a,b   Pisenti, Jacqueline ^c   Abbott, Ursula ^c   Morgan, Bruce ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Weill Cornell Medical Center   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CHICKEN; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMIS; GENE EXPRESSION; HOX GENE; LIMB BUD; MUTANT; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; GALLUS GALLUS;

EID: 0030297469     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1996.0265     Document Type: Article

References (36)

1. Carrington, J. L., and Fallon, J. F. (1988). Initial limb budding is independent of apical ectodermal ridge activity: Evidence from a limbless mutant. Development 104, 361-367.
2. Coelho, C. N. D., Krabbenhoft, K., Upholt, W. B., Fallon, J. F., and Kosher, R. A. (1991a). Altered expression of the chicken homeo-box-containing genes GHox-7 and GHox-8 in the limb buds of Limbless mutant chick embryos. Development 113, 1487-1493.
3. Cohn, M. J., Izpisua-Belmonte, J. C., Abud, H., and Heath, J. K. (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.
4. Crossley, P., and Martin, G. R. (1995). The mouse FGF-8 gene encodes a family of polypepetides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
5. Crossley, P. H., Minowada, G., MacArthur, C. A., and Martin, G. R. (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.
6. Davis, C., Holmyard, H., Millen, K., and Joyner, A. L. (1991). Examining pattern formation in mouse chicken and frog embryos with an En-specific antiserum. Development 111, 287-298.
7. Dealy, C. N., and Kosher, R. A. (1996). IGF-I, insulin and FGFs induce out growth of the limb buds of amelic mutant chick embryos. Development 122, 1323-1330.
8. Duprez, D., Kostakopoulo, K., Francis-West, P., Tickle, C., and Brickel, P. (1996). Activation of FGF-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb. Development 122, 1821-1828.
9. Fallon, J., Lopez, A., Ros, M., Savage, M., Olwin, B., and Simandl, B. (1994). FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107.
10. Francis, P. H., Richardson, M. K., Brickell, P. M., and Tickle, C. (1994). Bone morphogenetic proteins and a signaling pathway that controls patterning in the developing chick limb. Development 120, 209-218.
11. Francis-West, P. H., Robertson, K. E., Ede, D. A., Rodriquez, C., Izpisua-Belmonte, J. C., Houston, B., Burt, D. W., Gribbin, C., Brickell, P. M., and Tickle, C. (1995). Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3)limb buds: Their relationships in the signaling cascade involved in limb patterning. Dev. Dynamics 203, 187-197.
12. Gastrop, J., Hoevenagel, R., Young, J. R., and Clevers, H. C. (1992). A common ancestor of the mammalian transcription factors TCF-1 and TCF-1 alpha/LEF-1 expressed in chicken T cells. Eur. J. Immunol. 22, 1327-1330.
13. Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A., and Scott, M. P. (1996). Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev. 10, 301-312.
14. Hamburger, V., and Hamilton, H. L. (1951). A series of normal stages in the development of the chick embryo. J. Exp. Morphol. 88, 49-92.
15. Hayamizu, T. F., Wanek, N., Taylor, G., Trevino, C., Shi, C., Anderson, R., Gardiner, D. M., Muneoka, K., and Bryant, S. (1994). Regeneration of HoxD expression domains during pattern regulation in chick wing buds. Dev. Biol. 61, 504-512.
16. Heikinheimo, M., Lawshe, A., Shackleford, G., Wisol, D., and MacArthur, C. (1994). FGF-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs, and central nervous system. Mech. Dev. 48, 129-138.
17. Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A., and Tabin, C. (1994). Sonic hedgehog amd Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.
18. Marigo, V., Scott, M. P., Johnson, R. L., Goodrich, L. V., and Tabin, C. J. (1996). Conservation in hedgehog signaling: Induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233.
19. Morgan, B., and Fekete, D. (1996). Manipulating gene expression with replication competent retroviral vectors. In "Methods in Avian Embryology" (M. Bronner Frasier, Ed.), Methods in Cell Biology, Vol. 51, Academic Press, San Diego.
20. Nelson, C., Morgan, B., Burke, A., Laufer, E., Murtaugh, C., Di Mambro, E., Gonzales, E., Tessarollo, L., Parada, L., and Tabin, C. (1996). Analysis of Hox gene expression in the chick limb. Development 122, 1449-1466.
21. Niswander, L., Jeffrey, S., Martin, G. R., and Tickle, C. (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.
22. Niswander, L., and Martin, G. R. (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.
23. Niswander, L., Tickle, C., Vogel, A., Booth, I., and Martin, G. R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.
24. Parr, B. A., and McMahon, A. P. (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.
25. Parr, B. A., Shea, M. J., Vassileva, G., and McMahon, A. P. (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.
26. Patstone, G., Pasquale, E. B., and Maher, P. A. (1993). Different members of the fibroblast growth factor receptor family are specific to distinct cell types in the developing chicken embryo. Dev. Biol. 155, 107-123.
27. Prahlad, R., Skala, G., Jones, D., and Briles, W. (1979). Limbless: A new genetic mutant in the chick. J. Exp. Zool. 209, 427-434.
28. Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M., and Tabin, C. (1995). Induction of the LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.
29. Riddle, R. D., Johnson, R. L., Laufer, E., and Tabin, C. (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.
30. Robert, B., Lyons, G., Simandl, B. K., Kuroiwa, A., and Buckingham, M. (1991). The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes. Dev. 5, 2363-2374.
31. Ros, M. A., Lyons, G., Kosher, R. A., Upholt, W. B., Coelho, C. N. D., and Fallon, U. F. (1992). Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds. Development 116, 811-818.
32. Savage, M., Hart, C., Riley, B., Sasse, J., Olwin, B., and Fallon, J. (1993). The distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev. Dyn. 198, 159-170.
33. Vogel, A., Roberts-Clarke, D., and Niswander, L. (1995). Effect of FGF on gene expression in chick limb bud cells in vivo and in vitro. Dev. Biol. 171, 507-520.
34. Vogel, A., Rodriguez, C., Warnken, W., and Izipsua-Belmonte, J. C. (1995). Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720.
35. Wurst, W., Auerbach, A. B., and Joyner, A. L. (1994). Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hind-brain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.
36. Yang, Y., and Niswander, L. (1995). Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: Dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.