Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector

Journal of Virology

Volumn 71, Issue 4, 1997, Pages 3031-3038

  Caley, Ian J ^a   Betts, Michael R ^a   Irlbeck, David M ^a   Davis, Nancy L ^a   Swanstrom, Ronald ^a   Frelinger, Jeffrey A ^a   Johnston, Robert E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL CULTURE; CELLULAR IMMUNITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; IMMUNIZATION; IMMUNOGENETICS; IN SITU HYBRIDIZATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; VENEZUELAN EQUINE ENCEPHALOMYELITIS ALPHAVIRUS; VIRUS INFECTION;

EID: 0030891509     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.4.3031-3038.1997     Document Type: Article

References (54)

1. Altmeyer, R., N. Escriou, M. Girard, A. Palmenberg, and S. van der Werf. 1994. Attenuated Mengo virus as a vector for immunogenic human immunodeficiency virus type 1 glycoprotein 120. Proc. Natl. Acad. Sci. USA 91: 9775-9779.
2. Berglund, P., M. Sjöberg, H. Garoff, G. J. Atkins, B. J. Sheahan, and P. Liljeström. 1993. Semliki Forest virus expression system: production of conditionally infectious recombinant particles. Bio/Technology 11:916-920.
3. Berman, P. W., T. J. Gregory, L. Riddle, G. R. Nakumura, M. A. Champe, J. P. Porter, F. M. Wurm, R. D. Hershberg, E. K. Cobb, and J. W. Eichberg. 1990. Protection of chimpanzees from infection by HIV-1 after vaccination with recombinant glycoprotein gp120 but not gp160. Nature (London) 345: 622-625.
4. Burke, D. S., H. H. Ramsburg, and R. Edelman. 1977. Persistence in humans of antibody to subtypes of Venezuelan equine encephalomyelitis (VEE) virus after immunization with attenuated (TC-83) VEE virus vaccine. J. Infect. Dis. 136:354-359.
5. Caley, I. J., N. L. Davis, and R. E. Johnston. Unpublished results.
6. Charles, P. C., K. W. Brown, N. L. Davis, M. K. Hart, and R. E. Johnston. Mucosal-immunity induced by parenteral immunization with a live attenuated Venezuelan equine encephalitis virus vaccine candidate. Virology, in press.
7. Davis, N. L., K. W. Brown, G. F. Greenwald, A. J. Zajac, V. L. Zacny, J. F. Smith, and R. E. Johnston. 1995. Attenuated mutants of Venezuelan encephalitis virus containing lethal mutations in PE2 cleavage signal combined with a second-site suppressor mutation in E1. Virology 212:102-110.
8. Davis, N. L., K. W. Brown, and R. E. Johnston. 1966. A viral vaccine vector that expresses foreign genes in lymph nodes and protects against mucosal challenge. J. Virol. 70:3781-3787.
9. Davis, N. L., N. Powell, G. F. Greenwald, L. V. Willis, B. J. B. Johnson, J. F. Smith, and R. E. Johnston. 1991. Attenuating mutations in the E2 glycoprotein gene of Venezuelan equine encephalitis virus: construction of single and multiple mutants in a full-length cDNA clone. Virology 183:20-31.
10. Davis, N. L., L. V. Willis, J. F. Smith, and R. E. Johnston. 1989. In vitro synthesis of infectious Venezuelan equine encephalitis virus RNA from a cDNA clone: analysis of a viable deletion mutant. Virology 171:189-204.
11. Girard, M., M.-P. Kieny, A. Pinter, F. Barré-Sinoussi, P. Nara, H. Kolbe, K. Kisumi, A. Chaput, T. Rienhart, E. Muchmore, J. Ronco, M. Kaczorek, E. Gomard, J.-C. Gluckman, and P. N. Fultz. 1991. Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 88:542-546.
12. Girard, M., B. Meignier, F. Barré-Sinoussi, M.-P. Kieny, T. Matthews, E. Muchmore, P. L. Nara, Q. Wei, L. Rimsky, K. Weinhold, and P. N. Fultz. 1995. Vaccine-induced protection of chimpanzees against infection by a heterologous human immunodeficiency virus type 1. J. Virol. 69:6239-6248.
13. Grieder, F. B., N. L. Davis, J. A. Aronson, P. C. Charles, D. C. Sellon, K. Suzuki, and R. E. Johnston. 1995. Specific restrictions in the progression of Venezuelan equine encephalitis virus-induced disease resulting from single amino acid changes in the glycoproteins. Virology 206:994-1006.
14. Hahn, C. S., Y. S. Hahn, T. J. Braciale, and C. M. Rice. 1992. Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation. Proc. Natl. Acad. Sci. USA 89:2679-2683.
15. Haigwood, N. L., A. Watson, J. McClure, W. F. Sutton, J. Ranchalis, B. Travis, S.-L. Hu, V. M. Hirsch, G. Voss, N. L. Letvin, A. Lewis, and P. R. Johnson. 1995. Passive immune globulin therapy in the SIV/Macaque model reduces viremia and delays disease. Vaccines 95:149-158.
16. Harlow, E., and D. Lane. 1988. Immunoblotting, p. 479-504. In Antibodies: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
17. Haynes, B. F., G. Pantaleo, and A. S. Fauci. 1996. Towards an understanding of the correlates of protective immunity to HIV infection. Science 271:324-328.
18. Hirsch, M. S., and J. Curran. 1996. Human immunodeficiency viruses, p. 1953-1975. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
19. Honda, M., K. Matsuo, T. Nakasone, Y. Okamoto, H. Yoshizaki, K. Kitamura, W. Sugiura, K. Watanabe, Y. Fukushima, S. Haga, Y. Katsura, H. Tasaka, K. Komuro, T. Yamada, T. Asano, A. Yamazaki, and S. Yamazaki. 1995. Protective immune responses induced by secretion of a chimeric soluble protein from a recombinant Mycobacterium bovis bacillus Calmette-Guérin vector candidate vaccine for human immunodeficiency virus type 1 in small animals. Proc. Natl. Acad. Sci. USA 92:10693-10697.
20. Hu, S.-L., K. Abrams, G. N. Barber, P. Moran, J. M. Zarling, A. J. Langlois, L. Kuller, W. R. Morton, and R. E. Benveniste. 1992. Protection of macaques against SIV infection by subunit vaccines of SIV envelope glycoprotein gp160. Science 255:456-459.
21. Huang, H. V., C. M. Rice, C. Xiong, and S. Schlesinger. 1989. RNA viruses as gene expression vectors. Virus Genes 3:85-91.
22. Jahrling, P. B., and E. H. Stephenson. 1984. Protective efficacies of live attenuated and formaldehyde-inactivated Venezuelan equine encephalitis virus vaccines against aerosol challenge in hamsters. J. Clin. Microbiol. 19:429-431.
23. Javaherian, K., A. J. Langlois, G. J. LaRosa, A. T. Profy, D. P. Bolognesi, W. C. Herlihy, S. D. Putney, and T. J. Matthews. 1990. Broadly neutralizing antibodies elicited by the hypervariable neutralizing determinant of HIV-1. Science 250:1590-1593.
24. Johnston, R. E., and C. J. Peters. 1996. Alphaviruses, p. 843-894. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven, Philadelphia, Pa.
25. Kaplan, A. H., M. Manchester, and R. Swanstrom. 1994. Analysis of the role of the HIV-1 protease in virion assembly. Methods Enzymol. 241:58-69.
26. Karacostas, V., K. Nagashima, M. A. Gonda, and B. Moss. 1989. Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector. Proc. Natl. Acad. Sci. USA 86:8964-8967.
27. Kinney, R. M., J. J. Esposito, J. H. Matthews, B. J. B. Johnson, J. T. Roehrig, A. D. T. Barret, and D. W. Trent. 1988. Recombinant-vaccinia virus/Venezuelan equine encephalitis (VEE) virus protects mice from peripheral VEE virus challenge. J. Virol. 62:4697-4702.
28. Koup, R. A., J. T. Safrit, Y. Cao, C. A. Andrews, G. McLeod, W. Borkowsky, C. Farthing, and D. D. Ho. 1994. Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome. J. Virol. 68:4650-4655.
29. Kündig, T. M., M. F. Bachmann, C. DiPaolo, J. J. L. Simard, M. Battegay, H. Lother, A. Gessner, K. Kühlcke, P. S. Ohashi, H. Hengarter, and R. M. Zinkernagel.1995. Fibroblasts as efficient antigen-presenting cells in lymphoid organs. Science 268:1343-1347.
30. Laemmli, U. K. 1970. Cleavage of structural: proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
31. Lehner, T., L. A. Bergmeier, L. Tao, C. Panagiotidi, L. S. Klavinskis, L. Hussain, R. G. Ward, N. Meyers, S. E. Adams, A. J. H. Gearing, and R. Brookes. 1994. Targeted lymph node immunization with simian immunodeficiency virus p27 antigen to elicit genital, rectal, and urinary immune responses in nonhuman primates. J. Immunol. 153:1858-1868.
32. Lehner, T., Y. Wang, M. Cranage, L. A. Bergmeier, E. Mitchell, L. Tao, G. Hall, M. Dennis, N. Cook, R. Brookes, L. Klavinskis, I. Jones, C. Doyle, and R. Ward. 1996. Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat. Med. 2:767-775.
33. Liljeström, P., and H. Garoff. 1991. A new generation of animal cell expression vectors based on the Semliki Forest virus replicon. Bio/Technology 9: 1356-1361.
34. Lovett, A. E., C. S. Hahn, C. M. Rice, T. K. Frey, and J. S. Wolinsky. 1993. Rubella virus-specific cytotoxic T-lymphocyte responses: identification of the capsid as a target of major histocompatibility complex class I-restricted lysis and definition of two epitopes. J. Virol. 67:5849-5858.
35. Martin, S., A. Vyakarnam, R. Cheingsong-Popov, D. Callow, K. L. Jones, J. M. Senior, S. E. Adams, A. J. Kingsman, P. Matear, F. M. Gotch, A. J. McMichael, I. M. Roitt, and J. N. Weber. 1993. Immunization of human HIV-seronegative volunteers with recombinant p17/p24:Ty virus-like particles elicits p24-specific cellular and humoral immune responses. AIDS 7: 1315-1323.
36. Matsui, M., C. E. Hioe, and J. A. Frelinger. 1993. Roles of the six peptide-binding pockets of the HLA-A2 molecule in allorecognition by human cytotoxic T-cell clones. Proc. Natl. Acad. Sci. USA 90:674-678.
37. Moore, J. P., Y. Cao, J. Leu, L. Qin, B. Korber, and D. D. Ho. 1996. Inter-and intraclade neutralization of human immunodeficiency virus type 1: genetic clades do not correspond to neutralization serotypes but partially correspond to gp120 antigenic serotypes. J. Virol. 70:427-444.
38. Mossman, S. P., F. Bex, P. Berglund, J. Arthos, S. P. O'Neil, D. Riley, D. H. Maul, C. Bruck, P. Momin, A. Burny, P. N. Fultz, J. I. Mullins, P. Liljeström, and E. A. Hoover. 1996. Protection against lethal simian immunodeficiency virus SIVsmmPBj14 disease by a recombinant Semliki Forest virus gp160 vaccine and by a gp120 subunit vaccine. J. Virol. 70:1953-1960.
39. Murphy, B. R. 1995. Mucosal immunity to viruses, p. 333-343. In P. L. Ogra, et al. (ed.), Mucosal immunology, vol. 1. Cellular basis of mucosal immunity. Academic Press, San Diego, Calif.
40. Muster, T., B. Ferko, A. Klima, M. Purtscher, A. Trkola, P. Schulz, A. Grassauer, O. G. Engelhardt, A. García-Sástre, P. Palese, and H. Katinger. 1995. Mucosal model of immunization against human immunodeficiency virus type 1 with 3 chimeric influenza virus. 3. Virol. 69:6678-6686.
41. Newton, S. M., T. M. Joys, S. A. Anderson, R. C. Kennedy, M. E. Hovi, and B. A. Stocker. 1995. Expression and immunogenicity of an 18-residue epitope of HIV1 gp41 inserted in the flagellar protein Salmonella live vaccine. Res. Microbiol. 146:203-216.
42. Paul, W. E. 1995. Can the immune response control HIV infection?. Cell 82:177-182.
43. Porter, D. C., L. R. Melsen, R. W. Compans, and C. D. Morrow. 1996. Release of virus-like particles from cells infected with replicons which express human immunodeficiency virus type 1 Gag. J. Virol. 70:2643-2649.
44. Pratt, W. D., N. L. Davis, R. E. Johnston, and J. F. Smith. Unpublished results.
45. Ratner, L., A. Fisher, L. L. Jagodzinski, H. Mitsuya, R. C. Gallo, and F. Wong-Staal. 1987. Complete nucleotide sequences of functional clones of the AIDS virus. AIDS Res. Hum. Retroviruses 3:57-69.
46. Rice, C. M. 1992. Animal virus expression vectors. Semin. Virol. 3:237-310.
47. Salk, J., P. A. Bretscher, P. L. Salk, M. Clerici, and G. M. Shearer. 1993. A strategy for prophylactic vaccination against HIV. Science 260:1270-1272.
48. Sanmartine, C. 1972. Diseased hosts: man, p. 186-188. In Proceedings of the Workshop Symposium on Venezuelan Encephalitis Virus 1972. Pan American Health Organization, Washington, D.C.
49. Shafferman, A., P. B. Jahrling, R. E. Benveniste, M. G. Lewis, T. J. Phillips, F. Eden-McCutchan, J. Sadoff, G. A. Eddy, and D. S. Burke. 1991. Protection of macaques with a simian immunodeficiency virus envelope peptide vaccine based on conserved human immunodeficiency virus type 1 sequences. Proc. Natl. Acad. Sci. USA 88:7126-7130.
50. Staats, H. F., R. J. Jackson, M. Marinaro, I. Takahashi, H. Kiyono, and J. R. McGhee. 1994. Mucosal immunity to infection with implications for vaccine development. Curr. Opin. Immunol. 6:572-583.
51. Strauss, J. H., and E. G. Strauss. 1994. The alphaviruses: gene expression, replication, and evolution. Microbiol. Rev. 58:491-562.
52. Xiong, C., R. Levis, P. Shen, S. Schlesinger, C. M. Rice, and H. Huang. 1989. Sindbis virus: an efficient, broad host range vector for gene expression in animal cells. Science 243:1188-1191.
53. Zhou, X., P. Berglund, G. Rhodes, S. E. Parker, M. Jondal, and P. Liljeström. 1994. Self-replicating Semliki Forest virus RNA as recombinant vaccine. Vaccine 12:1510-1514.
54. Zhou, X., P. Berglund, H. Zhao, P. Liljeström, and M. Jondal. 1995. Generation of cytotoxic and humoral immune responses by nonreplicative recombinant Semliki Forest virus. Proc. Natl. Acad. Sci. USA 92:3009-3013.