메뉴 건너뛰기




Volumn 2, Issue 1, 1998, Pages 9-19

Molecular Events and Mechanisms of Apoptosis

Author keywords

[No Author keywords available]

Indexed keywords


EID: 0002043234     PISSN: 13850229     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009742830264     Document Type: Article
Times cited : (4)

References (121)
  • 1
    • 0015383455 scopus 로고
    • Apoptosis, a basic biological phenomenon with wider implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AH. Apoptosis, a basic biological phenomenon with wider implications in tissue kinetics. Br J Cancer 1972;26:239-245.
    • (1972) Br J Cancer , vol.26 , pp. 239-245
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.H.3
  • 3
    • 2342573607 scopus 로고
    • Cell death and disease process. The role of calcium
    • Bowen ID, Lockshin RA, eds. New York: Chapman and Hall
    • Trump BF, Berezesky IK, Osornio-Vargas AR. Cell death and disease process. The role of calcium. In: Cell death in biology and pathology. Bowen ID, Lockshin RA, eds. New York: Chapman and Hall, 1989:1-25.
    • (1989) Cell Death in Biology and Pathology , pp. 1-25
    • Trump, B.F.1    Berezesky, I.K.2    Osornio-Vargas, A.R.3
  • 5
    • 0021367846 scopus 로고
    • Glucocorticoid activation of a calcium-dependant endonuclease in thymocyte nuclei leads to cell death
    • Cohen JJ, Duke RC. Glucocorticoid activation of a calcium-dependant endonuclease in thymocyte nuclei leads to cell death. J Immunol 1984;132:38-42.
    • (1984) J Immunol , vol.132 , pp. 38-42
    • Cohen, J.J.1    Duke, R.C.2
  • 6
    • 0027217084 scopus 로고
    • Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50kb fragments prior to or in the absence of internucleosomal fragmentation
    • Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR, Sikorska M. Apoptotic death in epithelial cells: Cleavage of DNA to 300 and/or 50kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 1993;12:3670-3684.
    • (1993) EMBO J , vol.12 , pp. 3670-3684
    • Oberhammer, F.1    Wilson, J.W.2    Dive, C.3    Morris, I.D.4    Hickman, J.A.5    Wakeling, A.E.6    Walker, P.R.7    Sikorska, M.8
  • 7
    • 0027479655 scopus 로고
    • Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation
    • Brown DG, Sun XM, Cohen GM. Dexamethasone-induced apoptosis involves cleavage of DNA to large fragments prior to internucleosomal fragmentation. J Biol Chem 1993;268: 3037-3039.
    • (1993) J Biol Chem , vol.268 , pp. 3037-3039
    • Brown, D.G.1    Sun, X.M.2    Cohen, G.M.3
  • 10
    • 0022453954 scopus 로고
    • Modulation of the sensitivity of chromatin to exogenous nucleases: Implications for the apparent increased sensitivity of transcriptionally active genes
    • Walker PR, Sikorska M. Modulation of the sensitivity of chromatin to exogenous nucleases: Implications for the apparent increased sensitivity of transcriptionally active genes. Biochemistry 1986;25:3839-3845.
    • (1986) Biochemistry , vol.25 , pp. 3839-3845
    • Walker, P.R.1    Sikorska, M.2
  • 11
    • 0027164993 scopus 로고
    • Identification of deoxyribonuclease II as an endonuclease involved in apoptosis
    • Barry MA, Eastman A. Identification of deoxyribonuclease II as an endonuclease involved in apoptosis. Arc Biochem Biophys 1993;300:440-450.
    • (1993) Arc Biochem Biophys , vol.300 , pp. 440-450
    • Barry, M.A.1    Eastman, A.2
  • 12
    • 0028137453 scopus 로고
    • Apoptotic DNA degradation: Evidence for novel enzymes
    • Hughes FM, Cidlowski JA. Apoptotic DNA degradation: Evidence for novel enzymes. Cell Death Differ 1994;1: 11-17.
    • (1994) Cell Death Differ , vol.1 , pp. 11-17
    • Hughes, F.M.1    Cidlowski, J.A.2
  • 13
    • 0027145720 scopus 로고
    • Activation of a calcium and magnesium independent endonuclease in human leukemic cell apoptosis
    • Fernandes RS, Cotter TG. Activation of a calcium and magnesium independent endonuclease in human leukemic cell apoptosis. Anticancer Res 1993;13:1253-1260.
    • (1993) Anticancer Res , vol.13 , pp. 1253-1260
    • Fernandes, R.S.1    Cotter, T.G.2
  • 15
    • 0026505081 scopus 로고
    • Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumour cells undergoing apoptosis
    • Cotter TG, Lennon SV, Glynn JM, Green DR. Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumour cells undergoing apoptosis. Cancer Res 1992; 52:997-1005.
    • (1992) Cancer Res , vol.52 , pp. 997-1005
    • Cotter, T.G.1    Lennon, S.V.2    Glynn, J.M.3    Green, D.R.4
  • 16
    • 0025651121 scopus 로고
    • Disruption of micro tubules induces an endogenous suicide pathway in human leukemia HL60 cells
    • Martin SJ, Cotter TG. Disruption of micro tubules induces an endogenous suicide pathway in human leukemia HL60 cells. Cell Tiss Kinet 1991;23:545-559.
    • (1991) Cell Tiss Kinet , vol.23 , pp. 545-559
    • Martin, S.J.1    Cotter, T.G.2
  • 17
    • 0023159034 scopus 로고
    • Induction and activation of tissue transglutaminase during programmed cell death
    • Fesus L, Thomazy V, Falus A. Induction and activation of tissue transglutaminase during programmed cell death. FEBS Lett 1987;224:104-108.
    • (1987) FEBS Lett , vol.224 , pp. 104-108
    • Fesus, L.1    Thomazy, V.2    Falus, A.3
  • 18
    • 0024436687 scopus 로고
    • Phagocytosis of aged human neutrophils by a novel charge sensitive recognition mechanism
    • Savill JS, Henson PM, Haslett C. Phagocytosis of aged human neutrophils by a novel charge sensitive recognition mechanism. J Clin Invest 1989;90:1518-1527.
    • (1989) J Clin Invest , vol.90 , pp. 1518-1527
    • Savill, J.S.1    Henson, P.M.2    Haslett, C.3
  • 19
    • 0027485199 scopus 로고
    • Particle digestibility is required for induction of phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells
    • Fadok VA, Lazslo DJ, Noble PW, Weinstein L, Riches DWH, Henson PM. Particle digestibility is required for induction of phosphatidylserine recognition mechanism used by murine macrophages to phagocytose apoptotic cells. J Immunol 1993;151:4274-4285.
    • (1993) J Immunol , vol.151 , pp. 4274-4285
    • Fadok, V.A.1    Lazslo, D.J.2    Noble, P.W.3    Weinstein, L.4    Riches, D.W.H.5    Henson, P.M.6
  • 20
    • 0027057502 scopus 로고
    • Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognise and remove apoptotic cells
    • Fadok VA, Savill JS, Haslett C, Bratton DL, Doherty DE, Campbell PA, Henson PM. Different populations of macrophages use either the vitronectin receptor or the phosphatidylserine receptor to recognise and remove apoptotic cells. J Immunol 1992;149:4029-4035.
    • (1992) J Immunol , vol.149 , pp. 4029-4035
    • Fadok, V.A.1    Savill, J.S.2    Haslett, C.3    Bratton, D.L.4    Doherty, D.E.5    Campbell, P.A.6    Henson, P.M.7
  • 21
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin SJ, Reutlingsperger CP, McGahon AJ, Rader AJ, van-Schie RC, LaFace DM, Green DR. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. J Exp Med 1995; 182:1545-1556.
    • (1995) J Exp Med , vol.182 , pp. 1545-1556
    • Martin, S.J.1    Reutlingsperger, C.P.2    McGahon, A.J.3    Rader, A.J.4    Van-Schie, R.C.5    LaFace, D.M.6    Green, D.R.7
  • 22
    • 0002358317 scopus 로고
    • Ion signalling in apoptosis
    • Schimke RT, Mihich E, eds. New York: Plenum Press
    • Nicotera P, Zhirotovsky B, Bellamo G, Orrenius S. Ion signalling in apoptosis. In: Apoptosis. Schimke RT, Mihich E, eds. New York: Plenum Press, 1994:97-126.
    • (1994) Apoptosis , pp. 97-126
    • Nicotera, P.1    Zhirotovsky, B.2    Bellamo, G.3    Orrenius, S.4
  • 23
    • 0028670387 scopus 로고
    • Signalling and chromatin fragmentation in thymocyte apoptosis
    • McConkey DJ, Nicoterra P, Orrenius S. Signalling and chromatin fragmentation in thymocyte apoptosis. Immunol Rev 1994;142:343-363.
    • (1994) Immunol Rev , vol.142 , pp. 343-363
    • McConkey, D.J.1    Nicoterra, P.2    Orrenius, S.3
  • 24
  • 25
    • 0026504367 scopus 로고
    • Tumour necrosis factor a induces apoptosis in mammery adenocarcinoma cells by an increase in intracellular free calcium concentrations and DNA fragmentation
    • Bellomo G, Perotti M, Taddei F. Tumour necrosis factor a induces apoptosis in mammery adenocarcinoma cells by an increase in intracellular free calcium concentrations and DNA fragmentation. Cancer Res 1992;52:1342-1346.
    • (1992) Cancer Res , vol.52 , pp. 1342-1346
    • Bellomo, G.1    Perotti, M.2    Taddei, F.3
  • 26
    • 0025948955 scopus 로고
    • Evidence of early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid mediated apoptosis
    • Dowd DR, MacDonald PN, Kemm BS, Maussler MR, Miesfeld R. Evidence of early induction of calmodulin gene expression in lymphocytes undergoing glucocorticoid mediated apoptosis. J Biol Chem 1991;266:18423-18426.
    • (1991) J Biol Chem , vol.266 , pp. 18423-18426
    • Dowd, D.R.1    MacDonald, P.N.2    Kemm, B.S.3    Maussler, M.R.4    Miesfeld, R.5
  • 27
    • 0028827264 scopus 로고
    • Calpain inhibitor induced apoptosis in human prostate adenocarcinoma cells
    • Zhu W, Murtha PE, Toung CYF. Calpain inhibitor induced apoptosis in human prostate adenocarcinoma cells. Biochem Biophys Res Comm 1995;214:1130-1137.
    • (1995) Biochem Biophys Res Comm , vol.214 , pp. 1130-1137
    • Zhu, W.1    Murtha, P.E.2    Toung, C.Y.F.3
  • 28
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstrom PA. Oxidative stress as a mediator of apoptosis. Immunol Today 1994;15:7-10.
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 30
    • 0030565418 scopus 로고    scopus 로고
    • Reactive oxygen intermediates (ROI): Common mediator(s) of poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis
    • McGowan AJ, Ruiz-Ruiz MC, Gorman AM, Lopez Rivas A, Cotter TG. Reactive oxygen intermediates (ROI): Common mediator(s) of poly(ADP-ribose) polymerase (PARP) cleavage and apoptosis. FEBS Lett 1996;392:299-303.
    • (1996) FEBS Lett , vol.392 , pp. 299-303
    • McGowan, A.J.1    Ruiz-Ruiz, M.C.2    Gorman, A.M.3    Lopez Rivas, A.4    Cotter, T.G.5
  • 31
    • 0028837221 scopus 로고
    • The early intracellular production of a reactive oxygen intermediate mediates apoptosis in dexamethasone-treated thymocytes
    • Tores-Roca JF, Lecoeur H, Amatore C, Gougeon ML. The early intracellular production of a reactive oxygen intermediate mediates apoptosis in dexamethasone-treated thymocytes. Cell Death Differ 1995;2:309-319.
    • (1995) Cell Death Differ , vol.2 , pp. 309-319
    • Tores-Roca, J.F.1    Lecoeur, H.2    Amatore, C.3    Gougeon, M.L.4
  • 32
    • 0028815621 scopus 로고
    • Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
    • Nobel CSI, Kimland M, Lind B, Orrenius S, Slater AFG. Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. J Biol Chem 1995;270:26202-26208.
    • (1995) J Biol Chem , vol.270 , pp. 26202-26208
    • Nobel, C.S.I.1    Kimland, M.2    Lind, B.3    Orrenius, S.4    Slater, A.F.G.5
  • 35
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • Behl C, Davis JB, Lesley R, Schubert D. Hydrogen peroxide mediates amyloid beta protein toxicity. Cell 1994;77:817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 38
    • 0027990215 scopus 로고
    • Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death
    • Fernandes RS, Cotter TG. Apoptosis or necrosis: Intracellular levels of glutathione influence mode of cell death. Biochem Pharmacol 1994;48:675-681.
    • (1994) Biochem Pharmacol , vol.48 , pp. 675-681
    • Fernandes, R.S.1    Cotter, T.G.2
  • 39
    • 0028912676 scopus 로고
    • Proteolysis in cultured liver epithelial cells during oxidative stress
    • Grune T, Reinheckel T, Joshi M, Davies KJA. Proteolysis in cultured liver epithelial cells during oxidative stress. J Biol Chem 1995;270:2344-2351
    • (1995) J Biol Chem , vol.270 , pp. 2344-2351
    • Grune, T.1    Reinheckel, T.2    Joshi, M.3    Davies, K.J.A.4
  • 40
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoetic cell survival and cooperates with c-myc to immortalise pre-B cells
    • Vaux P, Cory S, Adams JM. Bcl-2 gene promotes haemopoetic cell survival and cooperates with c-myc to immortalise pre-B cells. Nature 1988;335:440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, P.1    Cory, S.2    Adams, J.M.3
  • 41
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerises in vivo with a conserved homolog Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL, Korsmeyer S. Bcl-2 heterodimerises in vivo with a conserved homolog Bax, that accelerates programmed cell death. Cell 1993;74:609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.3
  • 42
    • 0029318670 scopus 로고
    • A sticky buisness
    • Hacker G, Vaux DL. A sticky buisness. Curr Biol 1995; 5:622-624.
    • (1995) Curr Biol , vol.5 , pp. 622-624
    • Hacker, G.1    Vaux, D.L.2
  • 43
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the bcl-2 family
    • Reed JC. Double identity for proteins of the bcl-2 family. Nature 1997;387:773-776.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 45
    • 0027523461 scopus 로고
    • Apoptosis induced by withdrawal of interleukin-3 from an IL-3 dependent hematopoetic cell line is associated with a repartitioning of intracellular calcium and is blocked by enforced bcl-2 oncoprotein production
    • Baffy G, Miyashita T, Wiliamson TR, Reed JC. Apoptosis induced by withdrawal of interleukin-3 from an IL-3 dependent hematopoetic cell line is associated with a repartitioning of intracellular calcium and is blocked by enforced bcl-2 oncoprotein production. J Biol Chem 1993;268: 6511-6519.
    • (1993) J Biol Chem , vol.268 , pp. 6511-6519
    • Baffy, G.1    Miyashita, T.2    Wiliamson, T.R.3    Reed, J.C.4
  • 46
    • 0028216444 scopus 로고
    • Evidence that bcl-2 represses apoptosis by regulating endoplasmic recticulum associated calcium fluxes
    • Lam M, Dubyak G, Chen L, Nunez G, Miesfeld RL, Distelhorst CW. Evidence that bcl-2 represses apoptosis by regulating endoplasmic recticulum associated calcium fluxes. Proc Natl Acad Sci USA 1994;91:6569-6573.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6569-6573
    • Lam, M.1    Dubyak, G.2    Chen, L.3    Nunez, G.4    Miesfeld, R.L.5    Distelhorst, C.W.6
  • 50
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta converting enzyme
    • Yuan J, Shaham S, Ledoux S, Ellis HM, Horvitz HR. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta converting enzyme. Cell 1993;75:641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 52
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly (ADP-ribose) polymerse: An early marker for chemotherapy induced apoptosis
    • Kaufmann Sh, Desndyer S, Ottaviano Y, Davidson NE, Poirier GG. Specific proteolytic cleavage of poly (ADP-ribose) polymerse: An early marker for chemotherapy induced apoptosis. Cancer Res 1993;53:3976-3985.
    • (1993) Cancer Res , vol.53 , pp. 3976-3985
    • Kaufmann, Sh.1    Desndyer, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 53
    • 0028881847 scopus 로고
    • DNA dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis
    • Casciola-Rosen LA, Anhalt GJ, Rosen A. DNA dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. J Exp Med 1995;182: 1625-1634.
    • (1995) J Exp Med , vol.182 , pp. 1625-1634
    • Casciola-Rosen, L.A.1    Anhalt, G.J.2    Rosen, A.3
  • 54
    • 0028307171 scopus 로고
    • Split genes and RNA splicing
    • Sharp PA. Split genes and RNA splicing. Cell 1994;77: 805-815.
    • (1994) Cell , vol.77 , pp. 805-815
    • Sharp, P.A.1
  • 55
    • 0027999537 scopus 로고
    • Specific cleavage of the 70Kdal protein component of the small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death
    • Casciola-Rosen LA, Miller DK, Anhalt GJ, Rosen A. Specific cleavage of the 70Kdal protein component of the small nuclear ribonucleoprotein is a characteristic biochemical feature of apoptotic cell death. J Biol Chem 1994;269: 30757-30760.
    • (1994) J Biol Chem , vol.269 , pp. 30757-30760
    • Casciola-Rosen, L.A.1    Miller, D.K.2    Anhalt, G.J.3    Rosen, A.4
  • 57
    • 0027989510 scopus 로고
    • Chromatin condensation during apoptosis is accompanied by degradation of Lamin A+B, without enhanced activation of cdc-2 kinase
    • Oberhammer FA, Hochegger K, Froschl G, Tietenbacher R, Parelka M. Chromatin condensation during apoptosis is accompanied by degradation of Lamin A+B, without enhanced activation of cdc-2 kinase. J Biol Chem 1994; 126:827-837.
    • (1994) J Biol Chem , vol.126 , pp. 827-837
    • Oberhammer, F.A.1    Hochegger, K.2    Froschl, G.3    Tietenbacher, R.4    Parelka, M.5
  • 58
    • 0028788309 scopus 로고
    • Microfilament reorganisation during apoptosis: The role of Gas2, a possible substrate for ICE like proteases
    • Brancolini C, Benedetti M, Scheider C. Microfilament reorganisation during apoptosis: The role of Gas2, a possible substrate for ICE like proteases. EMBO J 1995;14: 5179-5190.
    • (1995) EMBO J , vol.14 , pp. 5179-5190
    • Brancolini, C.1    Benedetti, M.2    Scheider, C.3
  • 59
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997;89:175-184.
    • (1997) Cell , vol.89 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4
  • 60
    • 0028873964 scopus 로고
    • Fas and tumor necrosis factor induced apoptosis is inhibited by the poxvirus crmA gene product
    • Tewari M, Dixit VM. Fas and tumor necrosis factor induced apoptosis is inhibited by the poxvirus crmA gene product. J Biol Chem 1995;270:3255-3260.
    • (1995) J Biol Chem , vol.270 , pp. 3255-3260
    • Tewari, M.1    Dixit, V.M.2
  • 61
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1beta converting enzyme, a mammalian homologue of the C. elegans cell death gene ced-3
    • Miura M, Zhu H, Rotello R, Hartwieg EA, Yuan J. Induction of apoptosis in fibroblasts by IL-1beta converting enzyme, a mammalian homologue of the C. elegans cell death gene ced-3. Cell 1993;75:653-660.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 63
  • 64
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko LJ, Prives C. p53: puzzle and paradigm. Genes & Dev 1996;10:1054-1072.
    • (1996) Genes & Dev , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 65
    • 0021616838 scopus 로고
    • U.V. irradiation stimulates levels of p53 cellular tumour antigen in nontransformed mouse cells
    • Maltzman W, Czyzyk L. U.V. irradiation stimulates levels of p53 cellular tumour antigen in nontransformed mouse cells. Mol Cell Biol 1984;4:1689-1694.
    • (1984) Mol Cell Biol , vol.4 , pp. 1689-1694
    • Maltzman, W.1    Czyzyk, L.2
  • 66
    • 0029007316 scopus 로고
    • Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression
    • Sun X, Shimizu H, Yamamoto K. Identification of a novel p53 promoter element involved in genotoxic stress-inducible p53 gene expression. Mol Cell Biol 1995;15:4489-4496.
    • (1995) Mol Cell Biol , vol.15 , pp. 4489-4496
    • Sun, X.1    Shimizu, H.2    Yamamoto, K.3
  • 68
    • 0027332996 scopus 로고
    • Differential induction of transcriptionally active p53 following U.V. or ionising radiation: Defects in chromosome instability syndromes?
    • Lu X, Lane DP. Differential induction of transcriptionally active p53 following U.V. or ionising radiation: Defects in chromosome instability syndromes? Cell 1993;75:765-778.
    • (1993) Cell , vol.75 , pp. 765-778
    • Lu, X.1    Lane, D.P.2
  • 69
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan Q, Carrier F, Forance AJ. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol Cell Biol 1993;13:4242-4250.
    • (1993) Mol Cell Biol , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Forance, A.J.3
  • 71
    • 0029964158 scopus 로고    scopus 로고
    • A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage
    • Linke SP, Clarkin KC, DiLeonardo A, Tsou A, Wahl GM. A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. Genes & Dev 1996;10:934-947.
    • (1996) Genes & Dev , vol.10 , pp. 934-947
    • Linke, S.P.1    Clarkin, K.C.2    Dileonardo, A.3    Tsou, A.4    Wahl, G.M.5
  • 73
    • 0030910037 scopus 로고    scopus 로고
    • p53 and ATM: Cell cycle, cell death, and cancer
    • Morgan SE, Kastan MB. p53 and ATM: Cell cycle, cell death, and cancer. Adv Cancer Res 1997;71:1-25.
    • (1997) Adv Cancer Res , vol.71 , pp. 1-25
    • Morgan, S.E.1    Kastan, M.B.2
  • 74
    • 0029862307 scopus 로고    scopus 로고
    • The p53 tumour supressor gene: A mediator of G1 growth arrest and of apoptosis
    • Yonish-Rouach E. The p53 tumour supressor gene: A mediator of G1 growth arrest and of apoptosis. Experientia 1996;52:1001-1007.
    • (1996) Experientia , vol.52 , pp. 1001-1007
    • Yonish-Rouach, E.1
  • 75
    • 0027319521 scopus 로고
    • p53 is required for radiation induced apotosis in mouse thymocytes
    • Lowe SW, Schmidt SM, Smith SW, Osborne BA, Jacks T. p53 is required for radiation induced apotosis in mouse thymocytes. Nature 1993;362:847-849.
    • (1993) Nature , vol.362 , pp. 847-849
    • Lowe, S.W.1    Schmidt, S.M.2    Smith, S.W.3    Osborne, B.A.4    Jacks, T.5
  • 76
    • 0028883179 scopus 로고
    • Tumour supressor p53 is a direct transcription activator of the human bax gene
    • Miyashita T, Reed JC. Tumour supressor p53 is a direct transcription activator of the human bax gene. Cell 1995; 80:293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 79
    • 0029023560 scopus 로고
    • Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: Blocking p53 induced apoptosis unmasks G1 arrest
    • Guillouf C, Grana X, Selvakumaran M, De Luca XA, Giordano A, Hoffman B, Liebermann DA. Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: Blocking p53 induced apoptosis unmasks G1 arrest. Blood 1995;85:2691-2698.
    • (1995) Blood , vol.85 , pp. 2691-2698
    • Guillouf, C.1    Grana, X.2    Selvakumaran, M.3    De Luca, X.A.4    Giordano, A.5    Hoffman, B.6    Liebermann, D.A.7
  • 80
    • 0028882511 scopus 로고
    • DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective
    • Allday MJ, Inman GJ, Crawford DH, Farrell PJ. DNA damage in human B cells can induce apoptosis, proceeding from G1/S when p53 is transactivation competent and G2/M when it is transactivation defective. EMBO J 1995;14:4994-5005.
    • (1995) EMBO J , vol.14 , pp. 4994-5005
    • Allday, M.J.1    Inman, G.J.2    Crawford, D.H.3    Farrell, P.J.4
  • 81
    • 0028958705 scopus 로고
    • Growth factor modulation of p53-mediated growth arrest versus apoptosis
    • Canman CE, Gilmer TM, Coutts SB, Kastan MB. Growth factor modulation of p53-mediated growth arrest versus apoptosis. Genes & Dev 1995;9:600-611.
    • (1995) Genes & Dev , vol.9 , pp. 600-611
    • Canman, C.E.1    Gilmer, T.M.2    Coutts, S.B.3    Kastan, M.B.4
  • 82
    • 0030021748 scopus 로고    scopus 로고
    • Specific loss of apoptotic but not cell cycle arrest function in a human tumour derived p53 mutant
    • Rowan S, Ludwig RL, Haupt YH, Bates S, Lu X, Oren M, Vousden KH. Specific loss of apoptotic but not cell cycle arrest function in a human tumour derived p53 mutant. EMBO J 1996;15:827-838.
    • (1996) EMBO J , vol.15 , pp. 827-838
    • Rowan, S.1    Ludwig, R.L.2    Haupt, Y.H.3    Bates, S.4    Lu, X.5    Oren, M.6    Vousden, K.H.7
  • 83
    • 0028859541 scopus 로고
    • Bax-deficient mice with lymphoid hyperplasia and male germ cell death
    • Knudson C, Tunk K, Tourtellotte W, Brown G, Korsmeyer S. Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 1995;270:96-99.
    • (1995) Science , vol.270 , pp. 96-99
    • Knudson, C.1    Tunk, K.2    Tourtellotte, W.3    Brown, G.4    Korsmeyer, S.5
  • 86
    • 0028070989 scopus 로고
    • p53-dependant apoptosis in the absence of transcriptional activation of p53-target genes
    • Caelles C, Helmberg A, Karin M. p53-dependant apoptosis in the absence of transcriptional activation of p53-target genes. Nature 1994;370:220-223.
    • (1994) Nature , vol.370 , pp. 220-223
    • Caelles, C.1    Helmberg, A.2    Karin, M.3
  • 87
    • 0029092356 scopus 로고
    • Induction of apoptosis in HeLa cells by transactivation deficient p53
    • Haupt Y, Rowan S, Shaulian E, Vousden KH, Oren M. Induction of apoptosis in HeLa cells by transactivation deficient p53. Genes & Dev 1995;9:2170-2183.
    • (1995) Genes & Dev , vol.9 , pp. 2170-2183
    • Haupt, Y.1    Rowan, S.2    Shaulian, E.3    Vousden, K.H.4    Oren, M.5
  • 88
    • 0028978183 scopus 로고
    • Mice lacking p21PCII/WAF1 undergo normal development, but are defective in G1 checkpoint control
    • Deng C, Zhang P, Harrper JW, Elledge SJ, Leder P. Mice lacking p21PCII/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell 1995;82:675-684.
    • (1995) Cell , vol.82 , pp. 675-684
    • Deng, C.1    Zhang, P.2    Harrper, J.W.3    Elledge, S.J.4    Leder, P.5
  • 90
    • 0024596722 scopus 로고
    • A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumour necrosis factor
    • Yonehara S, Ishii A, Ynehara M. A cell-killing monoclonal antibody (anti-Fas) to a cell surface antigen co-downregulated with the receptor of tumour necrosis factor. J Exp Med 1989;169:1747-1756.
    • (1989) J Exp Med , vol.169 , pp. 1747-1756
    • Yonehara, S.1    Ishii, A.2    Ynehara, M.3
  • 91
    • 0028600059 scopus 로고
    • The Apo-1/Fas(CD95) receptor is expressed in homozygous Mrl/lpr mice
    • Mariani SM, Matiba B, Armanola EA, Krammer PH. The Apo-1/Fas(CD95) receptor is expressed in homozygous Mrl/lpr mice. Eur J Immunol 1994;24:3119-3123.
    • (1994) Eur J Immunol , vol.24 , pp. 3119-3123
    • Mariani, S.M.1    Matiba, B.2    Armanola, E.A.3    Krammer, P.H.4
  • 92
    • 0026568919 scopus 로고
    • Lymphoproliferative disorder in mice explained by defects in Fas antigen that mediates apotosis
    • Watanabe-Fukunga R, Brannan CI, Jenkins NA, Copeland NG, Suda T, Nagata S. Lymphoproliferative disorder in mice explained by defects in Fas antigen that mediates apotosis. Nature 1992;356:314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunga, R.1    Brannan, C.I.2    Jenkins, N.A.3    Copeland, N.G.4    Suda, T.5    Nagata, S.6
  • 95
    • 0027281373 scopus 로고
    • A novel protein domain required for apotosis. Mutational analysis of human Fas antigen
    • Itoh N, Nagata S. A novel protein domain required for apotosis. Mutational analysis of human Fas antigen. J Biol Chem 1993;268:10932-10937.
    • (1993) J Biol Chem , vol.268 , pp. 10932-10937
    • Itoh, N.1    Nagata, S.2
  • 96
    • 0028979548 scopus 로고
    • The death domain motif in Fas (Apo-1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance
    • Hofmann K, Tschoppp J. The death domain motif in Fas (Apo-1) and TNF receptor is present in proteins involved in apoptosis and axonal guidance. FEBS Lett 1995;371:321-323.
    • (1995) FEBS Lett , vol.371 , pp. 321-323
    • Hofmann, K.1    Tschoppp, J.2
  • 97
    • 0028883850 scopus 로고
    • Cytotoxicity dependent Apo1(Fas/CD95)-associated proteins (CAP) form a death inducing signal complex (DISC) with the receptor
    • Kischkel FC, Hellbardt S, Behrmann I, Germer M, Pawlita M, Krammer PH, Peter ME. Cytotoxicity dependent Apo1(Fas/CD95)-associated proteins (CAP) form a death inducing signal complex (DISC) with the receptor. EMBO J 1995;14:5579-5588.
    • (1995) EMBO J , vol.14 , pp. 5579-5588
    • Kischkel, F.C.1    Hellbardt, S.2    Behrmann, I.3    Germer, M.4    Pawlita, M.5    Krammer, P.H.6    Peter, M.E.7
  • 98
    • 85030199089 scopus 로고    scopus 로고
    • TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor-1 signaling complexes
    • Hsu H, Shu H-B, Pan MP, Goeddel DV. TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor-1 signaling complexes. Immunity 1996;4:387-396.
    • (1996) Immunity , vol.4 , pp. 387-396
    • Hsu, H.1    Shu, H.-B.2    Pan, M.P.3    Goeddel, D.V.4
  • 102
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 1997;88:355-365.
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 104
    • 0029022365 scopus 로고
    • Involvement of an ICE-like protease in Fas-mediated apoptosis
    • Enari M, Hug H, Nagata S. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 1995;375:78-81.
    • (1995) Nature , vol.375 , pp. 78-81
    • Enari, M.1    Hug, H.2    Nagata, S.3
  • 105
    • 0030044324 scopus 로고    scopus 로고
    • ICE-Lap3, a novel mammalian homologue of the C. elegans death protein CED-3, is activated during Fas and tumour necrosis factor induced apoptosis
    • Duan H, Chinnaiyan AM, Hudson PL, Wing JP, He W, Dixit VM. ICE-Lap3, a novel mammalian homologue of the C. elegans death protein CED-3, is activated during Fas and tumour necrosis factor induced apoptosis. J Biol Chem 1996;271:35013-35035.
    • (1996) J Biol Chem , vol.271 , pp. 35013-35035
    • Duan, H.1    Chinnaiyan, A.M.2    Hudson, P.L.3    Wing, J.P.4    He, W.5    Dixit, V.M.6
  • 108
    • 0030934465 scopus 로고    scopus 로고
    • Fas-associated death domain protein interleukin-1b-converting enzyme 2 (FLICE2), an ICE/ Ced-3 homologue is proximally involved in CD95-and p55-mediated death signalling
    • Vincenz C, Dixit VM. Fas-associated death domain protein interleukin-1b-converting enzyme 2 (FLICE2), an ICE/ Ced-3 homologue is proximally involved in CD95-and p55-mediated death signalling. Biol Chem 1997;272: 6578-6583.
    • (1997) Biol Chem , vol.272 , pp. 6578-6583
    • Vincenz, C.1    Dixit, V.M.2
  • 109
    • 0030024114 scopus 로고    scopus 로고
    • Fas mediated apoptosis and sphingomyelinase signal transduction: The role of ceramide as a second messenger for apoptosis
    • Skowronski EW, Kolesnick RN, Green DR. Fas mediated apoptosis and sphingomyelinase signal transduction: The role of ceramide as a second messenger for apoptosis. Cell Death Differ 1996;3:171-176.
    • (1996) Cell Death Differ , vol.3 , pp. 171-176
    • Skowronski, E.W.1    Kolesnick, R.N.2    Green, D.R.3
  • 110
    • 0025204548 scopus 로고
    • Bel-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery DM, Nuniz G, Milliman C Scheiber RD, Korsmeyer SJ. -Bel-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 1990;348: 334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.M.1    Nuniz, G.2    Milliman, C.3    Scheiber, R.D.4    Korsmeyer, S.J.5
  • 111
    • 0028019746 scopus 로고
    • Cell free apoptosis in Xenopus egg extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria
    • Newmeyer DD, Farschan DM, Reed JC. Cell free apoptosis in Xenopus egg extracts: Inhibition by bcl-2 and requirement for an organelle fraction enriched in mitochondria. Cell 1994;79:353-364.
    • (1994) Cell , vol.79 , pp. 353-364
    • Newmeyer, D.D.1    Farschan, D.M.2    Reed, J.C.3
  • 112
    • 14044251695 scopus 로고    scopus 로고
    • Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
    • Kroemer G. Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution. Cell Death Differ 1997;4:443-456.
    • (1997) Cell Death Differ , vol.4 , pp. 443-456
    • Kroemer, G.1
  • 114
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome-c from motochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck RM, Bossy-Wetzel E, Green DR, Newmeyer DD. The release of cytochrome-c from motochondria: A primary site for Bcl-2 regulation of apoptosis. Science 1997;275: 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 115
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell free extracts: Requirement for dATP and cytochrome c
    • Liu K, Kim NC, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell free extracts: Requirement for dATP and cytochrome c. Cell 1996;86:147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, K.1    Kim, N.C.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 116
  • 117
    • 0011374490 scopus 로고
    • Genetic control of programmed cell death in the nematode C. elegans
    • Ellis HM, Horvitz HR. Genetic control of programmed cell death in the nematode C. elegans. Cell 1986;75:641-652.
    • (1986) Cell , vol.75 , pp. 641-652
    • Ellis, H.M.1    Horvitz, H.R.2
  • 118
    • 0027525104 scopus 로고
    • The C. elegans death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta converting enzyme
    • Yuan JY, Shaham S, Ledoux S, Ellis HM, Horvitz HR. The C. elegans death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta converting enzyme. Cell 1993;75:641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.Y.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 119
    • 0027050145 scopus 로고
    • Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2
    • Vaux DL, Weissman IL, Kim SK. Prevention of programmed cell death in Caenorhabditis elegans by human bcl-2. Science 1992;258:1955-1957.
    • (1992) Science , vol.258 , pp. 1955-1957
    • Vaux, D.L.1    Weissman, I.L.2    Kim, S.K.3
  • 120
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED 4, participates in cytochrome-c dependent activation of caspase-3
    • Zou H, Henzel WJ, Liu X, Lutschg A, Wang X. Apaf-1, a human protein homologous to C. elegans CED 4, participates in cytochrome-c dependent activation of caspase-3. Cell 1997;90:405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3    Lutschg, A.4    Wang, X.5
  • 121
    • 0031034997 scopus 로고    scopus 로고
    • Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death
    • Chinnaiyan AM, O'Rourke K, Lane BR, Dixit VM. Interaction of CED-4 with CED-3 and CED-9: A molecular framework for cell death. Science 1997;275:1122-1126.
    • (1997) Science , vol.275 , pp. 1122-1126
    • Chinnaiyan, A.M.1    O'Rourke, K.2    Lane, B.R.3    Dixit, V.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.