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Volumn 63, Issue 22, 1998, Pages 7727-7737

Synthesis of N-Alkylated and N-Arylated Derivatives of 2-Amino-2′-hydroxy-l, 1′-binaphthyl (NOBIN) and 2,2′-Diamino-1, 1′'-binaphthyl and Their Application in the Enantioselective Addition of Diethylzinc to Aromatic Aldehydes a

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EID: 0001757279     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9807565     Document Type: Article
Times cited : (152)

References (126)
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    • Iphosphino-l,l'-binaphthyl (MAP) was used as the ligand instead of BINAP, the reaction was complete at 60 °C in 5 min, suggesting that aminophosphines may become the ligands of choice for the Hartwig-Buchwald coupling
    • note
    • Interestingly, when 2-amino-2'-diphenyIphosphino-l,l'-binaphthyl (MAP) was used as the ligand instead of BINAP, the reaction was complete at 60 °C in 5 min, suggesting that aminophosphines may become the ligands of choice for the Hartwig-Buchwald coupling. For the preparation of MAP, see the adjacent paper.
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    • note
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    • note
    • 28b,c
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    • note
    • 41b (note that a similar effect is known in cuprate chemistry). The latter approach is awaiting its chiral version, thereby opening an exciting new avenue to our NOBIN-derived ligands.
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