Synthesis of chiral N-aryl-α-amino acids by Pd-Cu catalyzed couplings of chiral α-amino acids with aryl halides

Tetrahedron Asymmetry

Volumn 7, Issue 11, 1996, Pages 3075-3078

  Ma, Dawei ^a   Yao, Jiangchao ^a  

^a SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE;

ARTICLE; CATALYSIS; CHIRALITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; TECHNIQUE;

EID: 0030575791     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/0957-4166(96)00401-6     Document Type: Article

References (19)

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17. +), 150, 148, 132, 104, 77.
18. +), 146, 117, 104, 77.
19. 3) for 6: δ 7.22 (m, 3H), 6.80 (t, J = 7.5 Hz, 1H), 6.67 (d, J = 7.8 Hz, 2H), 6.36 (s, 1H), 4.60 (m, 1H), 3.66 (s, 3H), 3.59 (d, J = 4.2 Hz, 1H), 2.38 (m, 1H), 1.39 (d, J = 7.3 Hz, 3H), 1.10 (d, J = 7.4 Hz, 3H), 1.04 (d, J = 7.4 Hz, 3H); for 7: δ 7.20 (m, 3H), 6.80 (t, J = 7.5 Hz, 1H), 6.62 (d, J = 7.8 Hz, 2H), 6.37 (s, 1H), 4.63 (m, 1H), 3.72 (s, 3H), 3.60 (d, J = 4.1 Hz, 1H), 2.40 (m, 1H), 1.26 (d, J = 7.4 Hz, 3H), 1.07 (d, J = 7.5 Hz, 3H), 1.03 (d, J = 7.5 Hz, 3H).