A facile synthesis of the enantiopure, nitrogen-substituted 2,2′-diamino-1,1′-binaphthyls as potential ligands for catalytic asymmetric reactions

Collection of Czechoslovak Chemical Communications

Volumn 63, Issue 4, 1998, Pages 515-519

  Vyskočil, Štěpǎn ^a,b   Smrčina, Martin ^a   Kočovský, Pavel ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Amine arylation: Palladium catalysis; Axial chirality; Biaryls; Binaphthyls; Chiral ligands: Amine reductive alkylation

Indexed keywords

EID: 0042941294     PISSN: 00100765     EISSN: None     Source Type: Journal    
DOI: 10.1135/cccc19980515     Document Type: Article

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16. All yields refer to "isolated" yields rather than "GC yields". All new compounds gave satisfactory analytical data.
17. 2 requires 326.1783).
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21. 3c.
22. 2 requires 360.1626).
23. R = 5.5 min). After prolonged reaction times, the results were as follows: ca 50% conversion of (±)-1 (60 °C. 2 h) gave 10% e.e.. ca 75% conversion (60 °C, 3 h) furnished 5% e.e., whereas ca 100% conversion (60 °C. 4 h) inevitably led to the racemic product.