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1542528892
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note
-
A sample of ligand 3a was recovered from two successive stoichiometric reactions and it was used to set up a catalytic (0.50 equiv of 3a) addition reaction to the imine 1a. The expected product was isolated in 79% yield and 81% ee, a value that is only slightly lower than the one obtained in the same catalytic reaction but using fresh ligand (Table 2, entry 1).
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1542424175
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We are grateful to Dr. Adolf Gogoll for helping to set up the experiment and to interpret the data
-
We are grateful to Dr. Adolf Gogoll for helping to set up the experiment and to interpret the data.
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-
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57
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1542528888
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The product was very hygroscopic
-
The product was very hygroscopic.
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