Drug equilibration across the blood-brain barrier - Pharmacokinetic considerations based on the microdialysis method

Pharmaceutical Research

Volumn 14, Issue 2, 1997, Pages 128-134

  Hammarlund Udenaes, Margareta ^a   Paalzow, Lennart K ^a   De Lange, Elizabeth C M ^b  

^a UPPSALA UNIVERSITY   (Sweden)

^b LEIDEN UNIVERSITY   (Netherlands)

Author keywords

Blood brain barrier transport; Drug equilibration; Microdialysis; Pharmacokintics

Indexed keywords

ATENOLOL; CAFFEINE; CARBAMAZEPINE; CYCLOSPORIN A; ETOPOSIDE; GLYCOPROTEIN P; PROBENECID; RHODAMINE 123; ZIDOVUDINE;

ACTIVE TRANSPORT; BLOOD BRAIN BARRIER; COMPUTER SIMULATION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG HALF LIFE; DRUG TRANSPORT; HYDROPHILICITY; INTRAVENOUS DRUG ADMINISTRATION; KINETICS; MICRODIALYSIS; PASSIVE TRANSPORT; PRIORITY JOURNAL; PROPRIOCEPTION; RABBIT; RAT; REVIEW; THEORY;

BIOLOGICAL TRANSPORT, ACTIVE; BLOOD-BRAIN BARRIER; BRAIN; HUMANS; MICRODIALYSIS; MODELS, THEORETICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS;

EID: 0030898087     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012080106490     Document Type: Review

References (38)

1. B. B. Brodie, H. Kurz, and L. S. Schanker. J. Pharmacol. Exp. Ther. 130:20-25 (1960).
2. E. C. M. De Lange, M. Danhof, A. G. de Boer, and D. D. Breimer. Brain Res. 666:1-8 (1994).
3. S. L. Wong, Y. Wang, and R. J. Sawchuk. Pharm. Res. 9:332-38 (1992).
4. E. Ljungdahl-Ståhle, E. Guzenda, D. Böttiger, B. Wahren, B. Öberg, and L. Ståhle. Antimicrob. Agents Chemother. 36:2418-22 (1992).
5. P. Sjöberg, I.-M. Olofsson, and T. Lundqvist. Pharm. Res. 9:1592-98 (1992).
6. K. Van Belle, S. Sarre, G. Ebinger, and Y. Michotte. J. Pharmacol. Exp. Ther. 272:1217-22 (1995).
7. C. Van Amsterdam and M. Lemaire. Eur. J. Pharm. Sci. in press (1996).
8. L. Ståhle, E. Guzenda, and E. Ljungdahl-Ståhle. J. Acquir. Immune Defic. Syndr. 6:435-439 (1993).
9. Y. Deguchi, K. Inabe, K. Tomiyasu, K. Nozawa, S. Yamada, and R. Kimura. Pharm. Res. 12:1838-44 (1995).
10. L. Ståhle, S. Segersvärd, and U. Ungerstedt. Life Sci. 49:1843-1852 (1991).
11. B. K. Malhotra, M. Lemaire, and R. J. Sawchuk. Pharm. Res. 11:1223-1232 (1994).
12. Y. Wang and D. F. Welty. Pharm. Res. 13:398-403 (1996).
13. E. C. M. de Lange, J. D. de Vries, C. Zurcher, M. Danhof, A. G. de Boer, and D. D. Breimer. Pharm. Res. 12:1924-31 (1995).
14. Q. Wang, H. Yang, D. W. Miller, and W. F. Elmquist. Biochem Biophys Res Commun. 211:719-26 (1995).
15. R. K. Dubey, C. B. McAllister, M. Inoue, and G. R. Wilkinson. J. Clin. Invest. 84:1155-1159 (1989).
16. E. P. Wala, W. R. Martin, and J. W. Sloan. Psychopharmacology. 105:535-540 (1991).
17. M. Telting-Diaz and C. E. Lunte. Pharm. Res. 10:44-48 (1993).
18. M. Rowland and T. N. Tozer. Clinical Pharmacokinetics: Concepts and Applications, 3rd ed. Williams & Wilkins, Media, USA, 1995.
19. T. Nakazono, T. Murakami, S. Sakai, Y. Higashi, and N. Yata. Chem. Pharm. Bull. 40:2510-15 (1992).
20. Y. Wang and R. J. Sawchuk. J. Pharm. Sci. 84:871-6 (1995).
21. W. H. Oldendorf. Proc Soc Exp Biol Med. 147:813-816 (1974).
22. V. Levin. J Med Chem. 23:682-684 (1980).
23. A. Gjedde, In M. W. B. Bradbury, Editor, Handbook of experimental pharmacology vol 103, Physiology and pharmacology of the blood-brain barrier., Springer-Verlag, Berlin, 1992, p. 65-115.
24. P. Agon, P. Goethals, D. Van Haver, and J.-M. Kaufman. J Pharm Pharmacol. 43:597-600 (1991).
25. S. L. Wong, K. van Belle, and R. J. Sawchuk. J. Pharmacol. Exp. Ther. 264:899-909 (1993).
26. J. M. Gallo, Y. Sanzgiri, E. W. Howerth, T. S. Finco, J. Wilson, J. Johnston, R. Tackett, and S. C. Budsberg. [published erratum appears in J Pharm Sci 1992 Mar;81(3):314]. J Pharm Sci. 81:11-5 (1992).
27. S. L. Wong, M. A. Hedaya, and R. J. Sawchuk. Pharm. Res. 9:228-235 (1992).
28. K. H. Dykstra, A. Arya, D. M. Arriola, P. M. Bungay, P. F. Morrison, and R. L. Dedrick. J. Pharmacol. Exp. Ther. 267:1227-1236 (1993).
29. K. D. K. Adkison, A. A. Artru, K. M. Powers, and D. D. Shen. J. Pharmacol. Exp. Ther. 268:797-805 (1994).
30. C. Cordon-Cardo, J. P. O'Brien, D. Casals, L. Rittman-Grauer, J. L. Biedler, M. R. Melamed, and J. R. Bertino. Proc Natl Acad Sci USA. 86:695-8 (1989).
31. I. Sugawara, H. Hirofumi, T. Tsuruo, and S. Mon. Jpn J Cancer Res. 81:727-30 (1990).
32. F. Thiebaut, T. Tsuruo, H. Hamada, M. M. Gottesman, I. Pastan, and M. C. Willingham. J Histochem Cytochem. 37:159-64 (1989).
33. A. H. Schinkel, J. J. M. Smit, O. Van Tellingen, J. H. Beijnen, E. Wagenaar, L. Van Deemter, C. A. A. M. Mol, M. A. Van Der Valk, E. C. Robanus-Maandag, H. P. J. Te Riele, A. J. M. Berns, and P. Borst. Cell. 77:491-502 (1994).
34. D. E. Burgio, M. P. Gosland, and P. J. McNamara. Biochem Pharmacol. 51:937-92 (1996).
35. D. F. Welty, G. P. Schielke, M. G. Vartanian, and C. P. Taylor. Epilepsy Res. 16:175-81 (1993).
36. M. Warner, A. Wyss, S. Yoshida, and J.-Å. Gustafsson. Meth Neurosci. 22:51-66 (1994).
37. L. B. Sheiner, D. R. Stanski, S. Vozeh, R. D. Miller, and J. Ham. Clin Pharmacol Ther. 25:358-371 (1979).
38. M. Gibaldi and D. Perrier. Pharmacokinetics, 2nd ed. Drugs and the pharmaceutical sciences; v. 15. Marcel Dekker, Inc., New York, 1982.