Effect of the Mdr1a P-glycoprotein gene disruption on the tissue distribution of SDZ PSC 833, a multidrug resistance-reversing agent, in mice

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 2, 1998, Pages 438-443

  Desrayaud, S ^a,b   De Lange, E C M ^c   Lemaire, M ^a   Bruelisauer, A ^a   De Boer, A G ^c   Breimer, D D ^c  

^a NOVARTIS PHARMA AG   (Switzerland)

^b HÔPITAL FERNAND WIDAL   (France)

^c LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN DERIVATIVE; GLYCOPROTEIN P; INULIN; VALSPODAR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CANCER RESISTANCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG PROTEIN BINDING; INTRAVENOUS DRUG ADMINISTRATION; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CYCLOSPORINS; DRUG RESISTANCE, MULTIPLE; MALE; MICE; MICE, KNOCKOUT; P-GLYCOPROTEIN; TISSUE DISTRIBUTION;

EID: 0031834184     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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