CD40 but not CD154 knockout mice have reduced inflammatory response in polymicrobial sepsis: A potential role for Escherichia coli heat shock protein 70 in CD40-mediated inflammation in vivo

Shock

Volumn 22, Issue 6, 2004, Pages 538-542

  Nolan, Anna ^a   Weiden, Michael D ^a   Hoshino, Yoshihiko ^a   Gold, Jeffrey A ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BELLEVUE HOSPITAL CENTER   (United States)

Author keywords

Cecal ligation and puncture; DnaK; IL 12; LPS; Macrophage

Indexed keywords

CD40 ANTIGEN; CD40 LIGAND; HEAT SHOCK PROTEIN 70; INTERLEUKIN 12; INTERLEUKIN 6; PROTEIN DNAK; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ESCHERICHIA COLI; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; KNOCKOUT MOUSE; MORTALITY; MOUSE; NONHUMAN; PROTEIN FUNCTION; SEPSIS; STRAIN DIFFERENCE; SURVIVAL;

ANIMALS; ANTIGENS, CD40; CD40 LIGAND; CECUM; ESCHERICHIA COLI; FEMALE; GENE DELETION; HSP70 HEAT-SHOCK PROTEINS; INFLAMMATION; INTERLEUKIN-12; INTERLEUKIN-6; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SEPSIS;

EID: 9644310303     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000143416.20649.30     Document Type: Article

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