Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome

Journal of Molecular and Cellular Cardiology

Volumn 37, Issue 6, 2004, Pages 1225-1233

  Gong, Qiuming ^a   Keeney, David R ^a   Robinson, Jeffrey C ^a   Zhou, Zhengfeng ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Arrhythmia; Ion channels; Mutations; Patch clamp; Protein trafficking

Indexed keywords

MONOMER; MUTANT PROTEIN; POTASSIUM CHANNEL HERG; TETRAMER;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KIDNEY CELL; LONG QT SYNDROME; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN STRUCTURE; SUCROSE DENSITY GRADIENT CENTRIFUGATION; WESTERN BLOTTING; WILD TYPE;

BLOTTING, WESTERN; CENTRIFUGATION, DENSITY GRADIENT; CODON, NONSENSE; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; LONG QT SYNDROME; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN TRANSPORT;

EID: 9644290757     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2004.10.002     Document Type: Article

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