Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 12, 2000, Pages 2327-2337

  Ficker, Eckhard ^a   Dennis, Adrienne T ^a   Obejero Paz, Carlos A ^a,c   Castaldo, Pasqualina ^b   Taglialatela, Maurizio ^b   Brown, Arthur M ^c  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Arrhythmia; ER retention; HERG; K+ channel; Trafficking

Indexed keywords

POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; COMPLEX FORMATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE MUTATION; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; LONG QT SYNDROME; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SUDDEN DEATH; SYNCOPE;

EID: 0034502477     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1263     Document Type: Article

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