Novel gain-of-function mechanism in K+ channel-related long-QT syndrome: Altered gating and selectivity in the HERG1 N629D mutant

Circulation Research

Volumn 86, Issue 5, 2000, Pages 507-513

  Lees Miller, James P ^a   Duan, Yanjun ^a   Teng, Guo Qi ^a   Thorstad, Kelly ^a   Duff, Henry J ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Gain of function; HERG1; K+ channel; Long QT syndrome

Indexed keywords

CESIUM; DOFETILIDE; MEGLUMINE; MONOVALENT CATION; POTASSIUM CHANNEL; POTASSIUM ION; SODIUM ION;

ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; LONG QT SYNDROME; POTASSIUM CURRENT; PRIORITY JOURNAL; REPOLARIZATION; SODIUM CURRENT; STRUCTURE ACTIVITY RELATION;

EID: 0034677902     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.86.5.507     Document Type: Article

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