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Volumn 13, Issue 5, 2004, Pages 565-571

Efficient early and sustained transduction of human fetal mesencephalon using adeno-associated virus type 2 vectors

Author keywords

Adeno associated virus (AAV); Dopaminergic grafts; Fetal mesencephalon; Parkinson's disease; Transplantation

Indexed keywords

ADENOVIRUS VECTOR; CASPASE INHIBITOR; GREEN FLUORESCENT PROTEIN; GROWTH FACTOR;

EID: 9344264643     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/000000004783983684     Document Type: Article
Times cited : (5)

References (45)
  • 2
    • 0030248550 scopus 로고    scopus 로고
    • The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum
    • Barker, R. A.; Dunnett, S. B.; Faissner, A.; Fawcett, J. W. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum. Exp. Neurol. 141:79-93; 1996.
    • (1996) Exp. Neurol. , vol.141 , pp. 79-93
    • Barker, R.A.1    Dunnett, S.B.2    Faissner, A.3    Fawcett, J.W.4
  • 3
    • 0033492260 scopus 로고    scopus 로고
    • Functional integration of neural grafts in Parkinson's disease
    • Barker, R. A.; Dunnett, S. B. Functional integration of neural grafts in Parkinson's disease. Nat. Neurosci. 2:1047-1048; 1999.
    • (1999) Nat. Neurosci. , vol.2 , pp. 1047-1048
    • Barker, R.A.1    Dunnett, S.B.2
  • 4
    • 0032550793 scopus 로고    scopus 로고
    • Selective and rapid uptake of adeno-associated virus type 2 in brain
    • Bartlett, J. S.; Samulski, R. J.; McCown, T. J. Selective and rapid uptake of adeno-associated virus type 2 in brain. Hum. Gene Ther. 9:1181-1186; 1998.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 1181-1186
    • Bartlett, J.S.1    Samulski, R.J.2    McCown, T.J.3
  • 5
    • 0030795798 scopus 로고    scopus 로고
    • Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioural impairment in a rat model of Parkinson disease
    • Bilang-Bleuel, A.; Revah, F.; Colin, P.; Locquet, I.; Robert, J. J.; Mallet, J.; Horellou, P. Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioural impairment in a rat model of Parkinson disease. Proc. Natl. Acad. Sci. USA 94:8818-8823; 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8818-8823
    • Bilang-Bleuel, A.1    Revah, F.2    Colin, P.3    Locquet, I.4    Robert, J.J.5    Mallet, J.6    Horellou, P.7
  • 6
    • 0025814934 scopus 로고
    • Neural transplantation: An experimental tool with clinical possibilities
    • Björklund, A. Neural transplantation: An experimental tool with clinical possibilities. Trends Neurosci. 14:319-322; 1991.
    • (1991) Trends Neurosci. , vol.14 , pp. 319-322
    • Björklund, A.1
  • 7
    • 0023281057 scopus 로고
    • Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host striatum
    • Bolam, J. P.; Freund, T. F.; Björklund, A.; Dunnett, S. B.; Smith, A. D. Synaptic input and local output of dopaminergic neurons in grafts that functionally reinnervate the host striatum. Exp. Brain Res. 68:131-146; 1987.
    • (1987) Exp. Brain Res. , vol.68 , pp. 131-146
    • Bolam, J.P.1    Freund, T.F.2    Björklund, A.3    Dunnett, S.B.4    Smith, A.D.5
  • 8
    • 0023933288 scopus 로고
    • Survival and function of dissociated rat dopamine neurons grafted at different developmental stages or after being cultured in vitro
    • Brundin, P.; Barbin, G.; Strecker, R. E.; Isacson, O.; Prochiantz, A.; Björklund, A. Survival and function of dissociated rat dopamine neurons grafted at different developmental stages or after being cultured in vitro. Dev. Brain Res. 39:233-243; 1988.
    • (1988) Dev. Brain Res. , vol.39 , pp. 233-243
    • Brundin, P.1    Barbin, G.2    Strecker, R.E.3    Isacson, O.4    Prochiantz, A.5    Björklund, A.6
  • 9
    • 0026584525 scopus 로고
    • Transplantation of fetal dopamine neurons in Parkinson's disease: One-year clinical and neurophysiological observations in two patients with putaminal implants
    • Brundin, P.; Odin, P.; Gustavii, B.; Frackowiak, R.; Leenders, K. L.; Sawle, G.; Rothwell, J. C. Transplantation of fetal dopamine neurons in Parkinson's disease: One-year clinical and neurophysiological observations in two patients with putaminal implants. Ann. Neurol. 31:155-165; 1992.
    • (1992) Ann. Neurol. , vol.31 , pp. 155-165
    • Brundin, P.1    Odin, P.2    Gustavii, B.3    Frackowiak, R.4    Leenders, K.L.5    Sawle, G.6    Rothwell, J.C.7
  • 10
    • 0036212994 scopus 로고    scopus 로고
    • Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system
    • Buchet, D.; Serguera, C.; Zennou, V.; Chameau, P.; Mallet, J. Long-term expression of beta-glucuronidase by genetically modified human neural progenitor cells grafted into the mouse central nervous system. Mol. Cell. Neurosci. 19:389-401; 2002.
    • (2002) Mol. Cell. Neurosci. , vol.19 , pp. 389-401
    • Buchet, D.1    Serguera, C.2    Zennou, V.3    Chameau, P.4    Mallet, J.5
  • 11
    • 0033168820 scopus 로고    scopus 로고
    • Diminished viability, growth, and behavioural efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: An argument for neurotrophic supplementation
    • Collier, T. J.; Sortwell, C. E.; Daley, B. F. Diminished viability, growth, and behavioural efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: An argument for neurotrophic supplementation. J. Neurosci. 19:5563-5573; 1999.
    • (1999) J. Neurosci. , vol.19 , pp. 5563-5573
    • Collier, T.J.1    Sortwell, C.E.2    Daley, B.F.3
  • 12
    • 0030000767 scopus 로고    scopus 로고
    • Efficient transduction of human neurons with an adeno-associated virus vector
    • Du, B.; Wu, P.; Boldt-Houle, D. M.; Terwilliger, E. F. Efficient transduction of human neurons with an adeno-associated virus vector. Gene Ther. 3:254-261; 1996.
    • (1996) Gene Ther. , vol.3 , pp. 254-261
    • Du, B.1    Wu, P.2    Boldt-Houle, D.M.3    Terwilliger, E.F.4
  • 14
    • 0030872521 scopus 로고    scopus 로고
    • Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: Implications for a gene therapy approach to epilepsy
    • Freese, A.; Kaplitt, M. G.; O'Connor, W. M.; Abbey, M.; Langer, D.; Leone, P.; O'Connor, M. J.; During, M. J. Direct gene transfer into human epileptogenic hippocampal tissue with an adeno-associated virus vector: Implications for a gene therapy approach to epilepsy. Epilepsia 38:759-766; 1997.
    • (1997) Epilepsia , vol.38 , pp. 759-766
    • Freese, A.1    Kaplitt, M.G.2    O'Connor, W.M.3    Abbey, M.4    Langer, D.5    Leone, P.6    O'Connor, M.J.7    During, M.J.8
  • 15
    • 0021916279 scopus 로고
    • Efferent connections of grafted dopaminergic neurons reinnervating the host neostriatum: A tyrosine hydroxylase immunocytochemical study
    • Freund, T. F.; Bolam, J. P.; Björklund, A.; Stenevi, U.; Dunnett, S. B.; Powell, J. F.; Smith, A. D. Efferent connections of grafted dopaminergic neurons reinnervating the host neostriatum: A tyrosine hydroxylase immunocytochemical study. J. Neurosci. 5:603-616; 1985.
    • (1985) J. Neurosci. , vol.5 , pp. 603-616
    • Freund, T.F.1    Bolam, J.P.2    Björklund, A.3    Stenevi, U.4    Dunnett, S.B.5    Powell, J.F.6    Smith, A.D.7
  • 16
    • 0034526673 scopus 로고    scopus 로고
    • The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture
    • Goggi, J.; Theofilopoulos, S.; Riaz, S. S.; Jauniaux, E.; Stern, G. M.; Bradford, H. F. The neuronal survival effects of rasagiline and deprenyl on fetal human and rat ventral mesencephalic neurones in culture. Neuroreport 11:3937-3941; 2000.
    • (2000) Neuroreport , vol.11 , pp. 3937-3941
    • Goggi, J.1    Theofilopoulos, S.2    Riaz, S.S.3    Jauniaux, E.4    Stern, G.M.5    Bradford, H.F.6
  • 17
    • 0032506752 scopus 로고    scopus 로고
    • Novel tools for production and purification of recombinant adeno-associated virus vectors
    • Grimm, D.; Kern, A.; Rittner, K.; Kleinschmidt, J. A. Novel tools for production and purification of recombinant adeno-associated virus vectors. Hum. Gene Ther. 9:2745-2760; 1998.
    • (1998) Hum. Gene Ther. , vol.9 , pp. 2745-2760
    • Grimm, D.1    Kern, A.2    Rittner, K.3    Kleinschmidt, J.A.4
  • 19
    • 0033550918 scopus 로고    scopus 로고
    • Effects of anaestehetics and lazaroid U-83836E on survival of transplanted rat dopaminergic neurones
    • Karlsson, J.; Love, R. M.; Clarke, D. J.; Brundin, P. Effects of anaestehetics and lazaroid U-83836E on survival of transplanted rat dopaminergic neurones. Brain Res. 13:546-550; 1999.
    • (1999) Brain Res. , vol.13 , pp. 546-550
    • Karlsson, J.1    Love, R.M.2    Clarke, D.J.3    Brundin, P.4
  • 20
    • 0030671240 scopus 로고    scopus 로고
    • Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: Establishment of a glial cell line with a functional CD4 receptor
    • Keir, S. D.; Miller, J.; Yu, G.; Hamilton, R.; Samulski, R. J.; Xiao, X.; Tornatore, C. Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: Establishment of a glial cell line with a functional CD4 receptor. J. Neurovirol. 3(5): 322-330; 1997.
    • (1997) J. Neurovirol. , vol.3 , Issue.5 , pp. 322-330
    • Keir, S.D.1    Miller, J.2    Yu, G.3    Hamilton, R.4    Samulski, R.J.5    Xiao, X.6    Tornatore, C.7
  • 21
    • 0034659835 scopus 로고    scopus 로고
    • Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: Intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system
    • Kirik, D.; Rosenblad, C.; Björklund, A.; Mandel, R. J. Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: Intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system J. Neurosci. 20:4686-4700; 2000.
    • (2000) J. Neurosci. , vol.20 , pp. 4686-4700
    • Kirik, D.1    Rosenblad, C.2    Björklund, A.3    Mandel, R.J.4
  • 22
    • 0032051603 scopus 로고    scopus 로고
    • Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors
    • Klein, R. L.; Meyer, E. M.; Peel, A. L.; Zolotukhin, S.; Meyers, C.; Muzyczka, N.; King, M. A. Neuron-specific transduction in the rat septohippocampal or nigrostriatal pathway by recombinant adeno-associated virus vectors. Exp. Neurol. 150:183-194; 1998.
    • (1998) Exp. Neurol. , vol.150 , pp. 183-194
    • Klein, R.L.1    Meyer, E.M.2    Peel, A.L.3    Zolotukhin, S.4    Meyers, C.5    Muzyczka, N.6    King, M.A.7
  • 23
    • 0028911848 scopus 로고
    • Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease
    • Kordower, J. H.; Freeman, T. B.; Snow, B. J.; Vingerhoets, F. J.; Mufson, E. J.; Sanberg, P. R.; Hauser, R. A.; Smith, D. A.; Nauert, G. M.; Perl, D. P. Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease. N. Engl. J. Med. 332:1118-1124; 1995.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 1118-1124
    • Kordower, J.H.1    Freeman, T.B.2    Snow, B.J.3    Vingerhoets, F.J.4    Mufson, E.J.5    Sanberg, P.R.6    Hauser, R.A.7    Smith, D.A.8    Nauert, G.M.9    Perl, D.P.10
  • 27
    • 0033585514 scopus 로고    scopus 로고
    • Adeno-associated virus-mediated gene transfer to the brain: Duration and modulation of expression
    • Lo, W. D.; Qu, G.; Sferra, T. J.; Clark, R.; Chen, R.; Johnson, P. R. Adeno-associated virus-mediated gene transfer to the brain: Duration and modulation of expression. Hum. Gene Ther. 20:201-213; 1999.
    • (1999) Hum. Gene Ther. , vol.20 , pp. 201-213
    • Lo, W.D.1    Qu, G.2    Sferra, T.J.3    Clark, R.4    Chen, R.5    Johnson, P.R.6
  • 28
    • 0027944626 scopus 로고
    • Programmed cell death in developing grafts of fetal substantia nigra
    • Mahalik, T. J.; Hahn, W. E.; Clayton, G. H.; Owens, G. P. Programmed cell death in developing grafts of fetal substantia nigra. Exp. Neurol. 129:27-36; 1994.
    • (1994) Exp. Neurol. , vol.129 , pp. 27-36
    • Mahalik, T.J.1    Hahn, W.E.2    Clayton, G.H.3    Owens, G.P.4
  • 29
    • 0031456051 scopus 로고    scopus 로고
    • Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
    • Mandel, R. J.; Spratt, S. K.; Snyder, R. O.; Leff, S. E. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc. Natl. Acad. Sci. USA 94:14083-14088; 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 14083-14088
    • Mandel, R.J.1    Spratt, S.K.2    Snyder, R.O.3    Leff, S.E.4
  • 30
    • 0036315299 scopus 로고    scopus 로고
    • Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain
    • Mastakov, M. Y.; Baer, K.; Symes, C. W.; Leichtlein, C. B.; Kotin, R. M.; During, M. J. Immunological aspects of recombinant adeno-associated virus delivery to the mammalian brain. J. Virol. 16:8446-8454; 2002.
    • (2002) J. Virol. , vol.16 , pp. 8446-8454
    • Mastakov, M.Y.1    Baer, K.2    Symes, C.W.3    Leichtlein, C.B.4    Kotin, R.M.5    During, M.J.6
  • 31
    • 0030003480 scopus 로고    scopus 로고
    • Differential and persistent expression patterns of CNS gene transfer by adeno-associated virus (AAV) vector
    • McCown, T. J.; Xiao, X.; Li, J.; Breese, G. R.; Samulski, R. J. Differential and persistent expression patterns of CNS gene transfer by adeno-associated virus (AAV) vector. Brain Res. 713:99-107; 1996.
    • (1996) Brain Res. , vol.713 , pp. 99-107
    • McCown, T.J.1    Xiao, X.2    Li, J.3    Breese, G.R.4    Samulski, R.J.5
  • 32
    • 0029981856 scopus 로고    scopus 로고
    • An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease
    • Morrish, P. K.; Sawle, G. V.; Brooks, D. J. An [18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease. Brain 119:585-591; 1996.
    • (1996) Brain , vol.119 , pp. 585-591
    • Morrish, P.K.1    Sawle, G.V.2    Brooks, D.J.3
  • 33
    • 0037106092 scopus 로고    scopus 로고
    • Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons
    • Ostenfeld, T.; Tai, Y. T.; Martin, P.; Deglon, N.; Aebischer, P.; Svendsen, C. N. Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons. J. Neurosci. Res. 69:955-965; 2002.
    • (2002) J. Neurosci. Res. , vol.69 , pp. 955-965
    • Ostenfeld, T.1    Tai, Y.T.2    Martin, P.3    Deglon, N.4    Aebischer, P.5    Svendsen, C.N.6
  • 34
    • 0028360518 scopus 로고
    • Bilateral motor improvement and alteration of L-DOPA effect in two patients with Parkinson's disease following intrastriatal transplantation of fetal ventral mesencephalon
    • Peschanski, M.; Defer, G.; N'Guyen, J. P.; Ricolfi, F.; Monfort, J. C.; Remy, P.; Geny, C.; Samson, Y.; Hantraye, P.; Jeny, R. Bilateral motor improvement and alteration of L-DOPA effect in two patients with Parkinson's disease following intrastriatal transplantation of fetal ventral mesencephalon. Brain 117:487-499; 1994.
    • (1994) Brain , vol.117 , pp. 487-499
    • Peschanski, M.1    Defer, G.2    N'Guyen, J.P.3    Ricolfi, F.4    Monfort, J.C.5    Remy, P.6    Geny, C.7    Samson, Y.8    Hantraye, P.9    Jeny, R.10
  • 37
    • 0031950832 scopus 로고    scopus 로고
    • Adeno-associated virus type 2-mediated gene transfer: Correlation of tyrosine phosphorylation of the cellular single-stranded D sequence-binding protein with transgene expression in human cells in vitro and murine tissues in vivo
    • Qing, K.; Khuntirat, B.; Mah, C.; Kube, D. M.; Wang, X. S.; Ponnazhagan, S.; Zhou, S.; Dwarki, V. J.; Yoder, M. C.; Srivastava, A. Adeno-associated virus type 2-mediated gene transfer: Correlation of tyrosine phosphorylation of the cellular single-stranded D sequence-binding protein with transgene expression in human cells in vitro and murine tissues in vivo. J. Virol. 72:1593-1599; 1998.
    • (1998) J. Virol. , vol.72 , pp. 1593-1599
    • Qing, K.1    Khuntirat, B.2    Mah, C.3    Kube, D.M.4    Wang, X.S.5    Ponnazhagan, S.6    Zhou, S.7    Dwarki, V.J.8    Yoder, M.C.9    Srivastava, A.10
  • 38
    • 0028220834 scopus 로고    scopus 로고
    • Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat
    • Sauer, H.; Oertel, W. H. Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: A combined retrograde tracing and immunocytochemical study in the rat. Neuroscience 59:401-415; 1996.
    • (1996) Neuroscience , vol.59 , pp. 401-415
    • Sauer, H.1    Oertel, W.H.2
  • 39
    • 0033008216 scopus 로고    scopus 로고
    • Caspase inhibition reduces apoptosis and increases survival of nigral transplants
    • Schierle, G. S.; Hansson, O.; Leist, M.; Nicotera, P.; Widner, H.; Brundin, P. Caspase inhibition reduces apoptosis and increases survival of nigral transplants. Nat. Med. 5:97-100; 1999.
    • (1999) Nat. Med. , vol.5 , pp. 97-100
    • Schierle, G.S.1    Hansson, O.2    Leist, M.3    Nicotera, P.4    Widner, H.5    Brundin, P.6
  • 41
    • 0014954436 scopus 로고
    • Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system
    • Ungerstedt, U.; Arbuthnott, G. W. Quantitative recording of rotational behavior in rats after 6-hydroxy-dopamine lesions of the nigrostriatal dopamine system. Brain Res. 24:485-493; 1970.
    • (1970) Brain Res. , vol.24 , pp. 485-493
    • Ungerstedt, U.1    Arbuthnott, G.W.2
  • 43
    • 0031779697 scopus 로고    scopus 로고
    • Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets
    • Wu, P.; Phillips, M. I.; Bui, J.; Terwilliger, E. F. Adeno-associated virus vector-mediated transgene integration into neurons and other nondividing cell targets. J. Virol. 72:5919-5926; 1998.
    • (1998) J. Virol. , vol.72 , pp. 5919-5926
    • Wu, P.1    Phillips, M.I.2    Bui, J.3    Terwilliger, E.F.4
  • 44
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-liter recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao, X.; Li, J.; Samulski, R. J. Production of high-liter recombinant adeno-associated virus vectors in the absence of helper adenovirus. J. Virol. 72:2224-2232; 1998.
    • (1998) J. Virol. , vol.72 , pp. 2224-2232
    • Xiao, X.1    Li, J.2    Samulski, R.J.3


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