Efficient gene transfer into primary and immortalized human fetal glial cells using adeno-associated virus vectors: Establishment of a glial cell line with a functional CD4 receptor

Journal of NeuroVirology

Volumn 3, Issue 5, 1997, Pages 322-330

  Keir, Stuart D ^a   Miller, Jeffrey ^b   Yu, Gang ^b   Hamilton, Rebecca ^a   Samulski, Richard J ^c   Xiao, Xiao ^c,d   Tornatore, Carlo ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d CELL GENESYS INC   (United States)

Author keywords

Adeno associated virus; Dependovirus; Gene expression; Glia

Indexed keywords

BETA GALACTOSIDASE; CD4 ANTIGEN; VIRUS ANTIGEN;

ADENO ASSOCIATED VIRUS; ARTICLE; CELL IMMORTALIZATION; CELL LINE; CONTROLLED STUDY; EXPRESSION VECTOR; FETUS; FETUS CELL; FLOW CYTOMETRY; GENE TRANSFER; GENETIC TRANSDUCTION; GLIA CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; REPORTER GENE; SYNCYTIUM; VIRUS RECOMBINANT;

ADENO-ASSOCIATED VIRUS; DEPENDOVIRUS; HUMAN IMMUNODEFICIENCY VIRUS; PARVOVIRUS;

EID: 0030671240     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: 10.3109/13550289709030746     Document Type: Article

References (28)

1. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA (1996). CC CKR5: A RANTES, MIP-1 alpha, MIP-1 beta receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958.
2. Anderson SM, Yu G, Giattina M, Miller JL (1996). Intercellular transfer of a glycosylphosphatidylinositol (GPI)-linked protein: release and uptake of CD4-GPI from recombinant adeno-associated virus transduced HeLa cells. Proc Natl Acad Sci USA 93: 5894-5898.
3. Byrnes AP, Rusby JE, Wood MJA, Charlton HM (1995). Adonovirus gene transfer causes inflammation in the brain. Neuroscience 66: 1015-1024.
4. Carter BJ (1992). Adeno-associated virus vectors. Curr Opin Biotechnol 3: 533-539.
5. Du B, Wu P, Boldt-Houle DM, Terwilligier EF (1996). Efficient transduction of human neurons with an adeno-associated virus vector. Gene Therapy 3: 254-261.
6. Flotte TR, Afione SA, Zeitlin PL (1994). Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration. Am J Respir Cell Mol Biol 11: 517-521.
7. Halbert CL, Alexander IE, Wolgamot GM, Miller AD (1995). Adeno-associated virus vectors transduce primary cell much less efficiently than immortalized cells. J Virol 69: 1473-1479.
8. Kaplitt MG, Leone P, Samulski RJ, Xiao X, Pfaff DW, O'Malley KL, During MJ (1994a). Long term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nature Genetics 8: 148-154.
9. Kaplitt MG, Kwong AD, Kleopoulos SP, Mobbs CV, Rabkin SD, Pfaff DW (1994b). Preproenkephalin promoter yields region-specific and long term expression in adult brain after direct in vivo gene transfer via a defective herpes simplex viral vector. Proc Natl Acad Sci USA 19: 8979-8983.
10. Keir SD, Mitchell WJ, Feldman LT, Martin JR (1995). Targeting and gene expression in spinal cord motor neurons following intramuscular inoculation of an HSV-1 vector. J Neurovirol 1: 259-267.
11. Major EO, Miller AE, Mourrain P, Traub RG, De Widt E (1985). Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proc Natl Acad Sci USA 82: 1257-1261.
12. Major EO and Vacante DA (1989). Human fetal astrocytes in culture support the growth of the neurotropic human polyomavirus, JCV. J Neuropathol Exp Neurol 48: 425-436.
13. Major EO, Amemiya K, Elder G, Houff SA (1990). Glial cells of the human developing brain and B cells of the immune system share a common DNA binding factor for recognition of the regulatory sequences of the human polyomavirus, JCV. J Neurosci Res 27: 461-471.
14. McCown TJ, Xiao X, Li J, Breese GR, Samulski RJ (1996). Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector. Brain Res 713: 99-107.
15. Neumann M, Felber BK, Kleinschmidt A, Froese B, Erfle V, Pavlakis GN, Brack-Werner R (1995). Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol 69: 2159-2167.
16. Peel AL, Zolotukhin S, Schrimsher GW, Muzyczka N, Reier PJ (1997). Efficient transduction of green fluorescent protein in spinal cord neurons using adeno-associated virus vectors containing cell type-specific promoters. Gene Therapy 4: 16-24.
17. Podsakoff G, Wong KK, Chatterjee S (1994). Efficient gene transfer into nondividing cells by adeno-associated virus based vectors. J Virol 68: 5656-5665.
18. Renfranz PJ, Cunningham MG, McKay RDG (1991). Region specific differentiation of the hippocampal stem cell line HiB5 upon implantation into the developing mammalian brain. Cell 66: 713-719.
19. Russell DW, Miller AD, Alexander IE (1994). Adeno-associated virus vectors preferentially transduce cells in S phase. Proc Natl Acad Sci USA 91: 8915-8919.
20. Sabate O, Horellou P, Vigene E, Colin P, Perricaudet M, Buc-Caron M, Mallet J (1995). Transplantation of human neural progenitors that were genetically modified using adenoviruses. Nature Genet 9: 256-260.
21. Samulski RJ, Chang LS, Shenk T (1987). A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol 61: 3096-3101.
22. Samulski RJ, Chang LS, Shenk T (1989). Helper free stocks of recombinant adeno-associated viruses: Normal integration does not require viral gene expression. J Virol 63: 3822-3828.
23. Snyder EY, Deitcher DL, Walsh C, Arnold-Aldea S, Hartweig EA, Cepko CL (1992). Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell 68: 33-51.
24. Snyder EY, Taylor RM, Wolfe JH (1995). Neural progenitor cell engraftment corrects lysosomal storage throughout the MPS VII mouse brain. Nature 374: 367-370.
25. Tornatore C, Meyers K, Atwood W, Conant K, Major E (1994). Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J Virol 68: 93-102.
26. Tornatore C, Baker-Cairns B, Yadid G, Hamilton R, Meyers K, Atwood W, Cummins A, Tanner V, Major E (1996). Expression of tyrosine hydroxylase in an immortalized human fetal astrocyte cell line; In vitro characterization and engraftment into the rodent striatum. Cell Transplantation 5: 145-163.
27. Volsky B, Sakai K, Reddy M, Volsky D (1992). A system for the high efficiency replication of HIV-1 in neural cells and its application to anti-viral evaluation. Virology 186: 303-308.
28. Whittemore SR, Neary JT, Kleitman N, Sanon HR, Benigno A, Donahue RP, Norenberg MD (1994). Isolation and characterization of conditionally immortalized astrocyte cell lines derived from adult human spinal cord. Glia 10: 211-226.