메뉴 건너뛰기




Volumn 6, Issue 2, 2004, Pages

Transforming growth factor-β induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein

Author keywords

cyclin dependent kinase 2; localization; p21; p27; transforming growth factor

Indexed keywords

CDK2 PROTEIN, HUMAN; CDK2 PROTEIN, MOUSE; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HRAS PROTEIN, HUMAN; PROTEIN P21; RAPAMYCIN; RETINOBLASTOMA PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN;

EID: 9144271919     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr762     Document Type: Article
Times cited : (23)

References (46)
  • 1
    • 0023110029 scopus 로고
    • Transforming growth factors and control of neoplastic cell growth
    • 1:CAS:528:DyaL2sXhsFCjsL0%3D, 3553215
    • J. Keski-Oja E.B. Leof R.M. Lyons R.J. Coffey Jr H.L. Moses Transforming growth factors and control of neoplastic cell growth J Cell Biochem 1987 33 95 107 1:CAS:528:DyaL2sXhsFCjsL0%3D 10.1002/jcb.240330204 3553215
    • (1987) J Cell Biochem , vol.33 , pp. 95-107
    • Keski-Oja, J.1    Leof, E.B.2    Lyons, R.M.3    Coffey, R.J.4    Moses, H.L.5
  • 2
    • 0029010734 scopus 로고
    • Mammary tumor suppression by transforming growth factor β1 transgene expression
    • 1:CAS:528:DyaK2MXls1altbo%3D, 7753792, 41922
    • D.F. Pierce Jr A.E. Gorska A. Chytil K.S. Meise D.L. Page R.J. Coffey Jr H.L. Moses Mammary tumor suppression by transforming growth factor β1 transgene expression Proc Natl Acad Sci USA 1995 92 4254 4258 1:CAS:528:DyaK2MXls1altbo%3D 10.1073/pnas.92.10.4254 7753792 41922
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 4254-4258
    • Pierce, D.F.1    Gorska, A.E.2    Chytil, A.3    Meise, K.S.4    Page, D.L.5    Coffey, R.J.6    Moses, H.L.7
  • 3
    • 0031441041 scopus 로고    scopus 로고
    • Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
    • 1:CAS:528:DyaK2sXotVGnt78%3D, 9407968
    • E.P. Bottinger J.L. Jakubczak D.C. Haines K. Bagnall L.M. Wakefield Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene Cancer Res 1997 57 5564 5570 1:CAS:528:DyaK2sXotVGnt78%3D 9407968
    • (1997) Cancer Res , vol.57 , pp. 5564-5570
    • Bottinger, E.P.1    Jakubczak, J.L.2    Haines, D.C.3    Bagnall, K.4    Wakefield, L.M.5
  • 4
    • 0034785348 scopus 로고    scopus 로고
    • TGF-β signaling in tumor suppression and cancer progression
    • 1:CAS:528:DC%2BD3MXnsFKgt7c%3D, 11586292
    • R. Derynck R.J. Akhurst A. Balmain TGF-β signaling in tumor suppression and cancer progression Nat Genet 2001 29 117 129 1:CAS:528:DC%2BD3MXnsFKgt7c%3D 10.1038/ng1001-117 11586292
    • (2001) Nat Genet , vol.29 , pp. 117-129
    • Derynck, R.1    Akhurst, R.J.2    Balmain, A.3
  • 5
    • 0033376724 scopus 로고    scopus 로고
    • Growth regulatory factors and carcinogenesis: the roles played by transforming growth factor beta, its receptors and signaling pathways
    • 1:CAS:528:DC%2BD3cXhsFaiu7Y%3D, 10697593
    • D.L. Kelly A. Rizzino Growth regulatory factors and carcinogenesis: the roles played by transforming growth factor beta, its receptors and signaling pathways AntiCancer Res 1999 19 4791 4807 1:CAS:528:DC%2BD3cXhsFaiu7Y%3D 10697593
    • (1999) AntiCancer Res , vol.19 , pp. 4791-4807
    • Kelly, D.L.1    Rizzino, A.2
  • 6
    • 0034469045 scopus 로고    scopus 로고
    • Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer
    • 1:CAS:528:DC%2BD3cXlsF2qsLY%3D, 11250700, 139432
    • M. Kretzschmar Transforming growth factor-beta and breast cancer: Transforming growth factor-beta/SMAD signaling defects and cancer Breast Cancer Res 2000 2 107 115 1:CAS:528:DC%2BD3cXlsF2qsLY%3D 10.1186/bcr42 11250700 139432
    • (2000) Breast Cancer Res , vol.2 , pp. 107-115
    • Kretzschmar, M.1
  • 7
    • 0035853883 scopus 로고    scopus 로고
    • Association between the T29→C polymorphism in the transforming growth factor β1 gene and breast cancer among elderly white women: the study of osteoporotic fractures
    • 1:CAS:528:DC%2BD3MXkvVOntrY%3D, 11401606
    • E. Ziv J. Cauley P.A. Morin R. Saiz W.S. Browner Association between the T29→C polymorphism in the transforming growth factor β1 gene and breast cancer among elderly white women: the study of osteoporotic fractures JAMA 2001 285 2859 2863 1:CAS:528:DC%2BD3MXkvVOntrY%3D 10.1001/jama.285.22.2859 11401606
    • (2001) JAMA , vol.285 , pp. 2859-2863
    • Ziv, E.1    Cauley, J.2    Morin, P.A.3    Saiz, R.4    Browner, W.S.5
  • 9
    • 0025329363 scopus 로고
    • Transforming growth factor β1 suppression of c-mycgene transcription: role in inhibition of keratinocyte proliferation
    • 1:CAS:528:DyaK3cXkslWrsrs%3D, 2187192, 53982
    • J.A. Pietenpol J.T. Holt R.W. Stein H.L. Moses Transforming growth factor β1 suppression of c-mycgene transcription: role in inhibition of keratinocyte proliferation Proc Natl Acad Sci USA 1990 87 3758 3762 1:CAS:528:DyaK3cXkslWrsrs%3D 10.1073/pnas.87.10.3758 2187192 53982
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 3758-3762
    • Pietenpol, J.A.1    Holt, J.T.2    Stein, R.W.3    Moses, H.L.4
  • 10
    • 0028910316 scopus 로고
    • Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor β1
    • 1:CAS:528:DyaK2MXltFSnt7c%3D, 7724545, 42141
    • M.G. Alexandrow M. Kawabata M. Aakre H.L. Moses Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor β1 Proc Natl Acad Sci USA 1995 92 3239 3243 1:CAS:528:DyaK2MXltFSnt7c%3D 10.1073/pnas.92.8.3239 7724545 42141
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3239-3243
    • Alexandrow, M.G.1    Kawabata, M.2    Aakre, M.3    Moses, H.L.4
  • 11
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-β-induced cell cycle arrest
    • 1:CAS:528:DyaK2cXmsVOqsbk%3D, 8078588
    • G.J. Hannon D. Beach p15INK4B is a potential effector of TGF-β-induced cell cycle arrest Nature 1994 371 257 261 1:CAS:528:DyaK2cXmsVOqsbk%3D 10.1038/371257a0 8078588
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 12
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • 1:CAS:528:DyaK2cXktVWku7c%3D, 8288131
    • K. Polyak J.Y. Kato M.J. Solomon C.J. Sherr J. Massague J.M. Roberts A. Koff p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest Genes Dev 1994 8 9 22 1:CAS:528:DyaK2cXktVWku7c%3D 10.1101/gad.8.1.9 8288131
    • (1994) Genes Dev , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 13
    • 0032563872 scopus 로고    scopus 로고
    • Insensitivity to growth inhibition by TGF-β1 correlates with a lack of inhibition of the CDK2 activity in prostate carcinoma cells
    • 1:CAS:528:DyaK1cXms1Ogtrg%3D, 9794232
    • S.C. Cipriano Y.Q. Chen Insensitivity to growth inhibition by TGF-β1 correlates with a lack of inhibition of the CDK2 activity in prostate carcinoma cells Oncogene 1998 17 1549 1556 1:CAS:528:DyaK1cXms1Ogtrg%3D 10.1038/sj.onc.1202069 9794232
    • (1998) Oncogene , vol.17 , pp. 1549-1556
    • Cipriano, S.C.1    Chen, Y.Q.2
  • 14
    • 0028873133 scopus 로고
    • Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression
    • 1:CAS:528:DyaK2MXjt12qtrs%3D, 7831315, 42765
    • J.K. Schwarz C.H. Bassing I. Kovesdi M.B. Datto M. Blazing S. George X.F. Wang J.R. Nevins Expression of the E2F1 transcription factor overcomes type β transforming growth factor-mediated growth suppression Proc Natl Acad Sci USA 1995 92 483 487 1:CAS:528:DyaK2MXjt12qtrs%3D 10.1073/pnas.92.2.483 7831315 42765
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 483-487
    • Schwarz, J.K.1    Bassing, C.H.2    Kovesdi, I.3    Datto, M.B.4    Blazing, M.5    George, S.6    Wang, X.F.7    Nevins, J.R.8
  • 15
    • 0030946933 scopus 로고    scopus 로고
    • E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor β through E2F binding sites
    • 1:CAS:528:DyaK2sXjtlegtrw%3D, 9144170, 24611
    • J.M. Li P.P. Hu X. Shen Y. Yu X.F. Wang E2F4-RB and E2F4-p107 complexes suppress gene expression by transforming growth factor β through E2F binding sites Proc Natl Acad Sci USA 1997 94 4948 4953 1:CAS:528:DyaK2sXjtlegtrw%3D 10.1073/pnas.94.10.4948 9144170 24611
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 4948-4953
    • Li, J.M.1    Hu, P.P.2    Shen, X.3    Yu, Y.4    Wang, X.F.5
  • 16
    • 0032933352 scopus 로고    scopus 로고
    • E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest
    • 1:CAS:528:DyaK1MXhvFyhsg%3D%3D, 9858615, 83949
    • A. Iavarone J. Massague E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest Mol Cell Biol 1999 19 916 922 1:CAS:528:DyaK1MXhvFyhsg%3D%3D 10.1128/MCB.19.1.916 9858615 83949
    • (1999) Mol Cell Biol , vol.19 , pp. 916-922
    • Iavarone, A.1    Massague, J.2
  • 17
    • 0032514376 scopus 로고    scopus 로고
    • Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway
    • 1:CAS:528:DyaK1cXls1Smsbs%3D, 9715279
    • M.J. West M. Stoneley A.E. Willis Translational induction of the c-myc oncogene via activation of the FRAP/TOR signalling pathway Oncogene 1998 17 769 780 1:CAS:528:DyaK1cXls1Smsbs%3D 10.1038/sj.onc.1201990 9715279
    • (1998) Oncogene , vol.17 , pp. 769-780
    • West, M.J.1    Stoneley, M.2    Willis, A.E.3
  • 18
    • 0027371861 scopus 로고
    • Rapamycin inhibition of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes
    • 1:CAS:528:DyaK3sXlslersrY%3D, 8226784
    • W.G. Morice G. Wiederrecht G.J. Brunn J.J. Siekierka R.T. Abraham Rapamycin inhibition of interleukin-2-dependent p33cdk2 and p34cdc2 kinase activation in T lymphocytes J Biol Chem 1993 268 22737 22745 1:CAS:528:DyaK3sXlslersrY%3D 8226784
    • (1993) J Biol Chem , vol.268 , pp. 22737-22745
    • Morice, W.G.1    Wiederrecht, G.2    Brunn, G.J.3    Siekierka, J.J.4    Abraham, R.T.5
  • 19
    • 0033000334 scopus 로고    scopus 로고
    • s6kintegrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes
    • 1:CAS:528:DyaK1MXktVCgsLY%3D, 10373522, 84271
    • s6kintegrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes Mol Cell Biol 1999 19 4729 4738 1:CAS:528:DyaK1MXktVCgsLY%3D 10.1128/MCB.19.7.4729 10373522 84271
    • (1999) Mol Cell Biol , vol.19 , pp. 4729-4738
    • Brennan, P.1    Babbage, J.W.2    Thomas, G.3    Cantrell, D.4
  • 20
    • 0036888908 scopus 로고    scopus 로고
    • Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
    • 1:CAS:528:DC%2BD38Xos1yhs7Y%3D, 12417722, 134072
    • B.K. Law A. Chytil N. Dumont E.G. Hamilton M.E. Waltner-Law M.E. Aakre C. Covington H.L. Moses Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells Mol Cell Biol 2002 22 8184 8198 1:CAS:528:DC%2BD38Xos1yhs7Y%3D 10.1128/MCB.22.23.8184-8198.2002 12417722 134072
    • (2002) Mol Cell Biol , vol.22 , pp. 8184-8198
    • Law, B.K.1    Chytil, A.2    Dumont, N.3    Hamilton, E.G.4    Waltner-Law, M.E.5    Aakre, M.E.6    Covington, C.7    Moses, H.L.8
  • 21
    • 0035131425 scopus 로고    scopus 로고
    • HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression
    • 1:CAS:528:DC%2BD3MXhtlGhtro%3D, 11238922, 86753
    • C. Hall D.M. Nelson X. Ye K. Baker J.A. DeCaprio S. Seeholzer M. Lipinski P.D. Adams HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression Mol Cell Biol 2001 21 1854 1865 1:CAS:528:DC%2BD3MXhtlGhtro%3D 10.1128/MCB.21.5.1854-1865.2001 11238922 86753
    • (2001) Mol Cell Biol , vol.21 , pp. 1854-1865
    • Hall, C.1    Nelson, D.M.2    Ye, X.3    Baker, K.4    DeCaprio, J.A.5    Seeholzer, S.6    Lipinski, M.7    Adams, P.D.8
  • 22
    • 0032999336 scopus 로고    scopus 로고
    • BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site
    • 1:CAS:528:DyaK1MXktVCgtr4%3D, 10373534, 84283
    • H. Ruffner W. Jiang A.G. Craig T. Hunter I.M. Verma BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site Mol Cell Biol 1999 19 4843 4854 1:CAS:528:DyaK1MXktVCgtr4%3D 10.1128/MCB.19.7.4843 10373534 84283
    • (1999) Mol Cell Biol , vol.19 , pp. 4843-4854
    • Ruffner, H.1    Jiang, W.2    Craig, A.G.3    Hunter, T.4    Verma, I.M.5
  • 23
    • 0032994432 scopus 로고    scopus 로고
    • Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6
    • 1:CAS:528:DyaK1MXksFKksL8%3D, 10339564, 26858
    • W. Jiang N.J. Wells T. Hunter Multistep regulation of DNA replication by Cdk phosphorylation of HsCdc6 Proc Natl Acad Sci USA 1999 96 6193 6198 1:CAS:528:DyaK1MXksFKksL8%3D 10.1073/pnas.96.11.6193 10339564 26858
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 6193-6198
    • Jiang, W.1    Wells, N.J.2    Hunter, T.3
  • 24
    • 0034665757 scopus 로고    scopus 로고
    • NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription
    • 1:CAS:528:DC%2BD3cXntVSksrw%3D, 10995386, 316937
    • J. Zhao B.K. Kennedy B.D. Lawrence D.A. Barbie A.G. Matera J.A. Fletcher E. Harlow NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription Genes Dev 2000 14 2283 2297 1:CAS:528:DC%2BD3cXntVSksrw%3D 10.1101/gad.827700 10995386 316937
    • (2000) Genes Dev , vol.14 , pp. 2283-2297
    • Zhao, J.1    Kennedy, B.K.2    Lawrence, B.D.3    Barbie, D.A.4    Matera, A.G.5    Fletcher, J.A.6    Harlow, E.7
  • 25
    • 0035877719 scopus 로고    scopus 로고
    • 199by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication
    • 1:CAS:528:DC%2BD3MXksFGlu7s%3D, 11278991
    • 199by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication J Biol Chem 2001 276 21529 21537 1:CAS:528:DC%2BD3MXksFGlu7s%3D 10.1074/jbc.M100014200 11278991
    • (2001) J Biol Chem , vol.276 , pp. 21529-21537
    • Tokuyama, Y.1    Horn, H.F.2    Kawamura, K.3    Tarapore, P.4    Fukasawa, K.5
  • 26
    • 0030849455 scopus 로고    scopus 로고
    • Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation
    • 1:CAS:528:DyaK2sXmtlOjtLk%3D, 9315635, 232425
    • E.S. Knudsen J.Y. Wang Dual mechanisms for the inhibition of E2F binding to RB by cyclin-dependent kinase-mediated RB phosphorylation Mol Cell Biol 1997 17 5771 5783 1:CAS:528:DyaK2sXmtlOjtLk%3D 10.1128/MCB.17.10.5771 9315635 232425
    • (1997) Mol Cell Biol , vol.17 , pp. 5771-5783
    • Knudsen, E.S.1    Wang, J.Y.2
  • 27
    • 0033037035 scopus 로고    scopus 로고
    • Rescue of cyclin D1 deficiency by knockin cyclin E
    • 1:CAS:528:DyaK1MXjvFOju7g%3D, 10380928
    • Y. Geng W. Whoriskey M.Y. Park R.T. Bronson R.H. Medema T. Li R.A. Weinberg P. Sicinski Rescue of cyclin D1 deficiency by knockin cyclin E Cell 1999 97 767 777 1:CAS:528:DyaK1MXjvFOju7g%3D 10.1016/S0092-8674(00)80788-6 10380928
    • (1999) Cell , vol.97 , pp. 767-777
    • Geng, Y.1    Whoriskey, W.2    Park, M.Y.3    Bronson, R.T.4    Medema, R.H.5    Li, T.6    Weinberg, R.A.7    Sicinski, P.8
  • 29
    • 0041854279 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
    • 1:CAS:528:DC%2BD3sXmslelsrw%3D, 12923533
    • S. Ortega I. Prieto J. Odajima A. Martin P. Dubus R. Sotillo J.L. Barbero M. Malumbres M. Barbacid Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice Nat Genet 2003 35 25 31 1:CAS:528:DC%2BD3sXmslelsrw%3D 10.1038/ng1232 12923533
    • (2003) Nat Genet , vol.35 , pp. 25-31
    • Ortega, S.1    Prieto, I.2    Odajima, J.3    Martin, A.4    Dubus, P.5    Sotillo, R.6    Barbero, J.L.7    Malumbres, M.8    Barbacid, M.9
  • 30
    • 0142116249 scopus 로고    scopus 로고
    • Cdk2 knockout mice are viable
    • 1:CAS:528:DC%2BD3sXot12itbk%3D, 14561402
    • C. Berthet E. Aleem V. Coppola L. Tessarollo P. Kaldis Cdk2 knockout mice are viable Curr Biol 2003 13 1775 1785 1:CAS:528:DC%2BD3sXot12itbk%3D 10.1016/j.cub.2003.09.024 14561402
    • (2003) Curr Biol , vol.13 , pp. 1775-1785
    • Berthet, C.1    Aleem, E.2    Coppola, V.3    Tessarollo, L.4    Kaldis, P.5
  • 31
    • 0041327168 scopus 로고    scopus 로고
    • Proliferation of cancer cells despite CDK2 inhibition
    • 1:CAS:528:DC%2BD3sXislOrtb0%3D, 12676582
    • O. Tetsu F. McCormick Proliferation of cancer cells despite CDK2 inhibition Cancer Cell 2003 3 233 245 1:CAS:528:DC%2BD3sXislOrtb0%3D 10.1016/S1535-6108(03)00053-9 12676582
    • (2003) Cancer Cell , vol.3 , pp. 233-245
    • Tetsu, O.1    McCormick, F.2
  • 32
    • 0029827323 scopus 로고    scopus 로고
    • Cyclin E/Cdk2 activity is controlled by different mechanisms in the G0 and G1 phases of the cell cycle
    • 1:STN:280:DyaK2s%2Fks1Cisw%3D%3D, 8891332
    • W.A. Bresnahan I. Boldogh T. Ma T. Albrecht E.A. Thompson Cyclin E/Cdk2 activity is controlled by different mechanisms in the G0 and G1 phases of the cell cycle Cell Growth Differ 1996 7 1283 1290 1:STN:280:DyaK2s%2Fks1Cisw%3D%3D 8891332
    • (1996) Cell Growth Differ , vol.7 , pp. 1283-1290
    • Bresnahan, W.A.1    Boldogh, I.2    Ma, T.3    Albrecht, T.4    Thompson, E.A.5
  • 33
    • 0030839599 scopus 로고    scopus 로고
    • Human cytomegalovirus infection results in altered Cdk2 subcellular localization
    • 1:CAS:528:DyaK2sXkvFCjtrk%3D, 9266999
    • W.A. Bresnahan E.A. Thompson T. Albrecht Human cytomegalovirus infection results in altered Cdk2 subcellular localization J Gen Virol 1997 78 1993 1997 1:CAS:528:DyaK2sXkvFCjtrk%3D 10.1099/0022-1317-78-8-1993 9266999
    • (1997) J Gen Virol , vol.78 , pp. 1993-1997
    • Bresnahan, W.A.1    Thompson, E.A.2    Albrecht, T.3
  • 34
    • 0344012519 scopus 로고    scopus 로고
    • Vitamin D inhibits G1 to S phase progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm
    • E.S. Yang K.L. Burnstein Vitamin D inhibits G1 to S phase progression in LNCaP prostate cancer cells through p27Kip1 stabilization and Cdk2 mislocalization to the cytoplasm J Biol Chem 2003 78 46862 46868 10.1074/jbc.M306340200
    • (2003) J Biol Chem , vol.78 , pp. 46862-46868
    • Yang, E.S.1    Burnstein, K.L.2
  • 35
    • 0034682818 scopus 로고    scopus 로고
    • Kip1, increases its protein stability
    • 1:CAS:528:DC%2BD3cXmtVeiurw%3D, 10831586
    • Kip1, increases its protein stability J Biol Chem 2000 275 25146 25154 1:CAS:528:DC%2BD3cXmtVeiurw%3D 10.1074/jbc.M001144200 10831586
    • (2000) J Biol Chem , vol.275 , pp. 25146-25154
    • Ishida, N.1    Kitagawa, M.2    Hatakeyama, S.3    Nakayama, K.4
  • 36
    • 0035803593 scopus 로고    scopus 로고
    • p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis
    • 1:CAS:528:DC%2BD3MXptVaqtLw%3D, 11726503, 125773
    • G. Rodier A. Montagnoli L. Di Marcotullio P. Coulombe G.F. Draetta M. Pagano S. Meloche p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis EMBO J 2001 20 6672 6682 1:CAS:528:DC%2BD3MXptVaqtLw%3D 10.1093/emboj/20.23.6672 11726503 125773
    • (2001) EMBO J , vol.20 , pp. 6672-6682
    • Rodier, G.1    Montagnoli, A.2    Di Marcotullio, L.3    Coulombe, P.4    Draetta, G.F.5    Pagano, M.6    Meloche, S.7
  • 41
    • 1542677089 scopus 로고    scopus 로고
    • Kip1at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization
    • 1:CAS:528:DC%2BD3sXptlGrsb8%3D, 14504289
    • Kip1at threonine 198 by p90 ribosomal protein S6 kinases promotes its binding to 14-3-3 and cytoplasmic localization J Biol Chem 2003 278 49254 49260 1:CAS:528:DC%2BD3sXptlGrsb8%3D 10.1074/jbc.M306614200 14504289
    • (2003) J Biol Chem , vol.278 , pp. 49254-49260
    • Fujita, N.1    Sato, S.2    Tsuruo, T.3
  • 42
    • 0037047268 scopus 로고    scopus 로고
    • Kip1promotes binding to 14-3-3 and cytoplasmic localization
    • 1:CAS:528:DC%2BD38XmsVGqtbw%3D, 12042314
    • Kip1promotes binding to 14-3-3 and cytoplasmic localization J Biol Chem 2002 277 28706 28713 1:CAS:528:DC%2BD38XmsVGqtbw%3D 10.1074/jbc.M203668200 12042314
    • (2002) J Biol Chem , vol.277 , pp. 28706-28713
    • Fujita, N.1    Sato, S.2    Katayama, K.3    Tsuruo, T.4
  • 43
    • 0037304898 scopus 로고    scopus 로고
    • New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?
    • 1:CAS:528:DC%2BD3sXmt1akuw%3D%3D, 12559756
    • O. Coqueret New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 2003 13 65 70 1:CAS:528:DC%2BD3sXmt1akuw%3D%3D 10.1016/S0962-8924(02)00043-0 12559756
    • (2003) Trends Cell Biol , vol.13 , pp. 65-70
    • Coqueret, O.1
  • 44
    • 0036049861 scopus 로고    scopus 로고
    • Cell cycling? Check your brakes
    • 1:CAS:528:DC%2BD38Xls1Ort7k%3D, 12149634
    • S.I. Reed Cell cycling? Check your brakes Nat Cell Biol 2002 4 E199 E201 1:CAS:528:DC%2BD38Xls1Ort7k%3D 10.1038/ncb0802-e199 12149634
    • (2002) Nat Cell Biol , vol.4 , pp. E199-E201
    • Reed, S.I.1
  • 45
    • 0037216528 scopus 로고    scopus 로고
    • kip1C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions
    • 1:CAS:528:DC%2BD3sXhtVOktA%3D%3D, 12482975, 140659
    • kip1C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions Mol Cell Biol 2003 23 216 228 1:CAS:528:DC%2BD3sXhtVOktA%3D%3D 10.1128/MCB.23.1.216-228.2003 12482975 140659
    • (2003) Mol Cell Biol , vol.23 , pp. 216-228
    • McAllister, S.S.1    Becker-Hapak, M.2    Pintucci, G.3    Pagano, M.4    Dowdy, S.F.5
  • 46
    • 0037405203 scopus 로고    scopus 로고
    • Sequence requirement for nuclear localization and growth inhibition of p27Kip1R, a degradation-resistant isoform of p27Kip1
    • 1:CAS:528:DC%2BD3sXjt1Wmtbo%3D, 12682919
    • K. Hirano Y. Zeng M. Hirano J. Nishimura H. Kanaide Sequence requirement for nuclear localization and growth inhibition of p27Kip1R, a degradation-resistant isoform of p27Kip1 J Cell Biochem 2003 89 191 202 1:CAS:528:DC%2BD3sXjt1Wmtbo%3D 10.1002/jcb.10499 12682919
    • (2003) J Cell Biochem , vol.89 , pp. 191-202
    • Hirano, K.1    Zeng, Y.2    Hirano, M.3    Nishimura, J.4    Kanaide, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.