Effect of ζ-globin substitution on the O 2-transport properties of Hb S in vitro and in vivo

Biochemical and Biophysical Research Communications

Volumn 325, Issue 4, 2004, Pages 1376-1382

  He, Zhenning ^a   Russell, J Eric ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Embryonic; Globin; Hemoglobin; O 2 affinity; Sickle cell disease therapy; Transgenic mice

Indexed keywords

GLOBIN; HEMOGLOBIN; OXYGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; ERYTHROCYTE; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OXYGEN TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PURIFICATION; SICKLE CELL ANEMIA; TISSUE OXYGENATION; TRANSGENIC MOUSE;

ANEMIA, SICKLE CELL; ANIMALS; BINDING SITES; BIOLOGICAL TRANSPORT, ACTIVE; GLOBINS; HEMOGLOBIN, SICKLE; HUMANS; HYDROGEN-ION CONCENTRATION; KINETICS; MICE; MICE, TRANSGENIC; OXYGEN; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRUCTURE-ACTIVITY RELATIONSHIP;

MUS MUSCULUS;

EID: 9144235948     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2004.10.180     Document Type: Article

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